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266.
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8 p, 343.3 KB |
The Relationship between social capital and quality management systems in European hospitals : A quantitative study
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Hammer, A (Institute for Medical Sociology, Health Services Research and Rehabilitation Science, Faculty of Human Science and Faculty of Medicine, University of Cologne) ;
Arah, Onyebuchi A.. (University of California Los Angeles Center for Health Policy Research) ;
Dersarkissian, Maral (Department of Epidemiology, University of California Los Angeles Fielding School of Public Health) ;
Thompson, Caroline A. (Department of Epidemiology, University of California Los Angeles Fielding School of Public Health) ;
Mannion, Russell (School of Social Policy, HSMC, University of Birmingham) ;
Wagner, Cordula (Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam) ;
Ommen, Oliver (Institute for Medical Sociology, Health Services Research and Rehabilitation Science, Faculty of Human Science and Faculty of Medicine, University of Cologne) ;
Suñol Sala, Rosa (Universitat Autònoma de Barcelona. Institut Universitari Avedis Donabedian) ;
Pfaff, Holger (Institute for Medical Sociology, Health Services Research and Rehabilitation Science, Faculty of Human Science and Faculty of Medicine, University of Cologne)
Strategic leadership is an important organizational capability and is essential for quality improvement in hospital settings. Furthermore, the quality of leadership depends crucially on a common set of shared values and mutual trust between hospital management board members. [...]
2013 -  10.1371/journal.pone.0085662
PloS one, Vol. 8 Num. 12 (december 2013)
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267.
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13 p, 470.0 KB |
Ultra-Deep Pyrosequencing (UDPS) Data Treatment to Study Amplicon HCV Minor Variants
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Gregori i Font, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteban Mur, Juan Ignacio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cubero, María Dolores (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garcia-Cehic, D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Perales Viejo, Celia (Centro de Biología Molecular Severo Ochoa) ;
Casillas, Rosario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alvarez-Tejado, Miguel (Roche Diagnostics, Sant Cugat del Vallès) ;
Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guardia Massó, Jaume (Universitat Autònoma de Barcelona) ;
Domingo, Esteban (Centro de Biología Molecular Severo Ochoa) ;
Quer, Josep 1963- (Universitat Autònoma de Barcelona)
We have investigated the reliability and reproducibility of HCV viral quasispecies quantification by ultra-deep pyrosequencing (UDPS) methods. Our study has been divided in two parts. First of all, by UDPS sequencing of clone mixes samples we have established the global noise level of UDPS and fine tuned a data treatment workflow previously optimized for HBV sequence analysis. [...]
2013 - 10.1371/journal.pone.0083361
PloS one, Vol. 8 (december 2013)
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268.
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7 p, 319.4 KB |
Risk Taking in Hospitalized Patients with Acute and Severe Traumatic Brain Injury
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Fecteau, Shirley (Harvard Medical School, Boston, Massachusetts, United States of America) ;
Levasseur-Moreau, Jean (Laval University, Quebec city, Canada) ;
García-Molina, Alberto (Institut Germans Trias i Pujol. Institut Guttmann) ;
Kumru, Hatice (Institut Germans Trias i Pujol. Institut Guttmann) ;
Vergara, Raúl Pelayo (Institut Germans Trias i Pujol. Institut Guttmann) ;
Bernabeu Guitart, Montserrat (Institut Germans Trias i Pujol. Institut Guttmann) ;
Roig, Teresa (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, José Maria (Institut Germans Trias i Pujol. Institut Guttmann)
Rehabilitation can improve cognitive deficits observed in patients with traumatic brain injury (TBI). However, despite rehabilitation, the ability of making a choice often remains impaired. Risk taking is a daily activity involving numerous cognitive processes subserved by a complex neural network. [...]
2013 - 10.1371/journal.pone.0083598
PloS one, Vol. 8 (december 2013)
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269.
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7 p, 420.4 KB |
Patterns of Anti-Osteoporosis Medication Use among Women at High Risk of Fracture : Findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)
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Gehlbach, Stephen (University of Massachusetts Medical School, Worcester, Massachusetts, United States of America) ;
Hooven, Frederick H. (University of Massachusetts Medical School, Worcester, Massachusetts, United States of America) ;
Wyman, Allison (University of Massachusetts Medical School, Worcester, Massachusetts, United States of America) ;
Díez Pérez, Adolfo (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Adachi, Jonathan D. (Saint Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada) ;
Luo, Xuemei (Pfizer, Groton, Connecticut, United States of America) ;
Bushmakin, Andrew G. (Pfizer, Groton, Connecticut, United States of America) ;
Anderson, Frederick A. (University of Massachusetts Medical School, Worcester, Massachusetts, United States of America)
To assess patterns of anti-osteoporosis medication (AOM) use over 3 years among women at high risk of major fracture. The GLOW registry follows a cohort of more than 40,000 women aged ≥55 from 615 primary care practices in 10 countries. [...]
2013 - 10.1371/journal.pone.0082840
PloS one, Vol. 8 (december 2013)
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270.
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28 p, 5.7 MB |
A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of Ca2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca 2+ Influx
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Bahamonde, María Isabel (Universitat Pompeu Fabra) ;
Serra, Selma Angèlica (Universitat Pompeu Fabra) ;
Drechsel, Oliver (Universitat Pompeu Fabra) ;
Rahman, Rubayte (Universitat Pompeu Fabra) ;
Marcé-Grau, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prieto, Marta (Universitat Pompeu Fabra) ;
Ossowski, Stephan (Universitat Pompeu Fabra) ;
Macaya Ruiz, Alfons (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernández-Fernández, José M. (Universitat Pompeu Fabra) ;
Universitat Autònoma de Barcelona
Mutations in the CACNA1A gene, encoding the pore-forming Ca2. 1 (P/Q-type) channel α subunit, result in heterogeneous human neurological disorders, including familial and sporadic hemiplegic migraine along with episodic and progressive forms of ataxia. [...]
2015 - 10.1371/journal.pone.0146035
PloS one, Vol. 10 (december 2015)
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271.
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19 p, 1.1 MB |
Mortality, Causes of Death and Associated Factors Relate to a Large HIV Population-Based Cohort
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Garriga, César (Instituto de Salud Carlos III) ;
García de Olalla, Patricia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Miró, Josep M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ocaña Rivera, Immaculada (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Knobel Freud, Hernando (Hospital del Mar (Barcelona, Catalunya)) ;
Barberà, Maria Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Humet, Victoria (Generalitat de Catalunya. Direcció General de Serveis Penitenciaris i de Rehabilitació) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Gatell, Josep M.. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ribera, Esteve (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gurguí, Mercè (Institut d'Investigació Biomèdica Sant Pau) ;
Marco, Andrés (Generalitat de Catalunya. Direcció General de Serveis Penitenciaris i de Rehabilitació) ;
Caylà, Joan A.. (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Antiretroviral therapy has led to a decrease in HIV-related mortality and to the emergence of non-AIDS defining diseases as competing causes of death. This study estimates the HIV mortality rate and their risk factors with regard to different causes in a large city from January 2001 to June 2013. [...]
2015 - 10.1371/journal.pone.0145701
PloS one, Vol. 10 (december 2015)
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272.
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15 p, 563.3 KB |
Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus
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Caballero, Andrea (Hospital Universitari Vall d'Hebron) ;
Gregori i Font, Josep (Roche Diagnostics S.L., Sant Cugat del Vallès) ;
Homs, Maria (Hospital Universitari Vall d'Hebron) ;
Tabernero, David (Hospital Universitari Vall d'Hebron) ;
González, Carolina (Hospital Universitari Vall d'Hebron) ;
Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Blasi, Maria (Hospital Universitari Vall d'Hebron) ;
Casillas, Rosario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nieto, Leonardo (Hospital Universitari Vall d'Hebron) ;
Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ;
Esteban, Rafael (Esteban Mur) (Hospital Universitari Vall d'Hebron) ;
Buti, Maria (Hospital Universitari Vall d'Hebron) ;
Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
This study assesses the presence and outcome of genotype mixtures in the polymerase/surface and X/preCore regions of the HBV genome in patients with chronic hepatitis B virus (HBV) infection. Thirty samples from ten chronic hepatitis B patients were included. [...]
2015 - 10.1371/journal.pone.0144816
PloS one, Vol. 10 (december 2015)
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273.
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20 p, 2.3 MB |
Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells
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Teichenne, Joan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Morró Larrubia, Meritxell (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Casellas, Alba (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Jimenez, Veronica (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Tellez, Noelia (Institut d'Investigació Biomèdica de Bellvitge) ;
Leger, Adrien (University of Nantes and Atlantic Gene Therapies) ;
Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Ayuso, Eduard (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG))
Reprogramming acinar cells into insulin producing cells using adenoviral (Ad)-mediated delivery of Pdx1, Ngn3 and MafA (PNM) is an innovative approach for the treatment of diabetes. Here, we aimed to investigate the molecular mechanisms involved in this process and in particular, the role of microRNAs. [...]
2015 - 10.1371/journal.pone.0145116
PloS one, Vol. 10, Issue 12 (December 2015) , art. e0145116
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274.
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21 p, 2.1 MB |
Transcriptome Analysis of Ullrich Congenital Muscular Dystrophy Fibroblasts Reveals a Disease Extracellular Matrix Signature and Key Molecular Regulators
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Paco, Sonia (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Casserras, Teresa (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rodríguez, Maria Angels (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Jou, Cristina (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Puigdelloses, Montserrat (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Ortez González, Carlos Ignacio (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Gallardo, Eduard (Institut d'Investigació Biomèdica Sant Pau) ;
Colomer, Jaume (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Nascimento, Andrés (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Kalko, Susana G. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Jiménez Mallebrera, Cecilia (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Universitat Autònoma de Barcelona
Collagen VI related myopathies encompass a range of phenotypes with involvement of skeletal muscle, skin and other connective tissues. They represent a severe and relatively common form of congenital disease for which there is no treatment. [...]
2015 - 10.1371/journal.pone.0145107
PloS one, Vol. 10 (december 2015)
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275.
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13 p, 274.5 KB |
HIV-1/HAART-Related Lipodystrophy Syndrome (HALS) Is Associated with Decreased Circulating sTWEAK Levels
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López-Dupla, Miguel (Hospital Universitari Joan XXIII de Tarragona) ;
Maymó-Masip, Elsa (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Martínez, Esteban (Hospital Clínic i Provincial de Barcelona) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Leal, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Peraire, Joaquim (Hospital Universitari Joan XXIII de Tarragona) ;
Viladés, Consuelo (Hospital Universitari Joan XXIII de Tarragona) ;
Veloso, Sergi (Hospital Universitari Joan XXIII de Tarragona) ;
Arnedo, Mireia (Hospital Clínic i Provincial de Barcelona) ;
Ferrando-Martínez, Sara (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Beltrán-Debón, Raúl (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Alba, Verónica (Hospital Universitari Joan XXIII de Tarragona. Institut d'Investigació Sanitària Pere Virgili) ;
Gatell, Josep Mª (Hospital Clínic i Provincial de Barcelona) ;
Vendrell, Joan (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Vidal, Francesc (Hospital Universitari Joan XXIII de Tarragona) ;
Chacón, Matilde R. (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Universitat Autònoma de Barcelona
Obesity and HIV-1/HAART-associated lipodystrophy syndrome (HALS) share clinical, pathological and mechanistic features. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a multifunctional cytokine that plays an important role in obesity and related diseases. [...]
2015 - 10.1371/journal.pone.0144789
PloS one, Vol. 10 (december 2015)
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