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17 p, 921.2 KB |
Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes
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Sauta, Elisabetta (Humanitas Clinical and Research Center (Itàlia)) ;
Robin, Marie (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis (França)) ;
Bersanelli, Mateo (Department of Biomedical Sciences. Humanitas University) ;
Travaglino, Erica (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Meggendorfer, Manje (Mll Munich Leukemia Laboratory) ;
Zhao, Lin-Pierre (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis (França)) ;
Caballero Berrocal, Juan Carlos (Hematology Department. Hospital Universitario de Salamanca) ;
Sala, Claudia (Experimental. Diagnostic and Specialty Medicine. Dimes) ;
Maggioni, Giulia (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Bernardi, Massimo (University Vita-Salute San Raffaele (Itàlia)) ;
Di Grazia, Carmen (Irccs Ospedale Policlinico San Martino) ;
Vago, Luca (University Vita-Salute San Raffaele (Itàlia)) ;
Rivoli, Giulia (Irccs Ospedale Policlinico San Martino) ;
Borin, Lorenza (Ospedale San Gerardo) ;
D'Amico, Saverio (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Tentori, Cristina Astrid (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Ubezio, Marta (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Campagna, Alessia (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Russo, Antonio (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Mannina, Daniele (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Lanino, Luca (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Chiusolo, Patrizia (Università Cattolica Del Sacro Cuore) ;
Giaccone, Luisa (Department of Molecular Biotechnology and Health Sciences. University of Turin) ;
Voso, Maria Teresa (Tor Vergata University) ;
Riva, Maria (Asst Grande Ospedale Metropolitano Niguarda) ;
Oliva, Esther Natalie (Grande Ospedale Metropolitano Bianchi Melacrino Morelli) ;
Zampini, Matteo (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Riva, Elena (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Nibourel, Olivier (Chu Lille) ;
Bicchieri, Marinela (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Bolli, Niccolo (Department of Oncology and Hemato-Oncology. University of Milan) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni Xxiii) ;
Passamonti, Francesco (Department of Medicine and Surgery. University of Insubria) ;
Savevski, Victor (IRCCS Humanitas Clinical and Research Center (Milà, Itàlia)) ;
Santoro, Armando (Department of Biomedical Sciences. Humanitas University) ;
Germing, Ulrich (Department of Hematology. Heinrich-Heine-University. University Clinic) ;
Kordasti, Shahram (Hematology Department. DISCLIMO-Università Politecnica Delle Marche) ;
Santini, Valeria (University of Florence) ;
Diez-Campelo, María (Hospital Universitario de Salamanca) ;
Sanz, Guillermo (Hospital Universitari i Politècnic La Fe (València)) ;
Sole, F (Institut de Recerca Contra la Leucèmia Josep Carreras) ;
Kern, Wolfgang (Mll Munich Leukemia Laboratory) ;
Platzbecker, Uwe (University Hospital Leipzig) ;
Arenillas, Leonor (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis) ;
Fenaux, Pierre (Department of Hematology and Bone Marrow Transplantation. Hôpital Saint-Louis) ;
Haferlach, Torsten (Mll Munich Leukemia Laboratory) ;
Castellani, Gastone (Experimental. Diagnostic and Specialty Medicine. Dimes) ;
Della Porta, Matteo Giovanni (Department of Biomedical Sciences. Humanitas University)
PURPOSEMyelodysplastic syndromes (MDS) are heterogeneous myeloid neoplasms in which a risk-adapted treatment strategy is needed. Recently, a new clinical-molecular prognostic model, the Molecular International Prognostic Scoring System (IPSS-M) was proposed to improve the prediction of clinical outcome of the currently available tool (Revised International Prognostic Scoring System [IPSS-R]). [...]
2023 -  10.1200/JCO.22.01784
Journal of Clinical Oncology, Vol. 41 Núm. 15 (20 2023) , p. 2827-2842
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16 p, 3.8 MB |
Genetic and phenotypic attributes of splenic marginal zone lymphoma
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Bonfiglio, Ferdinando (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bruscaggin, Alessio (Institute of Oncology Research, Bellinzona, Switzerland) ;
Guidetti, Francesca (Institute of Oncology Research, Bellinzona, Switzerland) ;
Terzi di Bergamo, Lodovico (Institute of Oncology Research, Bellinzona, Switzerland) ;
Faderl, Martin (Institute of Oncology Research, Bellinzona, Switzerland) ;
Spina, Valeria (Institute of Oncology Research, Bellinzona, Switzerland) ;
Condoluci, Adalgisa (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bonomini, Luisella (International Extranodal Lymphoma Study Group, Bellinzona, Switzerland) ;
Forestieri, Gabriela (Institute of Oncology Research, Bellinzona, Switzerland) ;
Koch, Ricardo (Institute of Oncology Research, Bellinzona, Switzerland) ;
Piffaretti, Deborah (Institute of Oncology Research, Bellinzona, Switzerland) ;
Pini, Katia (Institute of Oncology Research, Bellinzona, Switzerland) ;
Pirosa, Maria Cristina (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Cittone, Micol Giulia (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Arribas, Alberto (Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland) ;
Lucioni, Marco (Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Pavia, Italy) ;
Ghilardi, Guido (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.) ;
Wu, Wei (Institute of Oncology Research, Bellinzona, Switzerland) ;
Arcaini, Luca (University of Pavia, Pavia, Italy.) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bastidas-Mora, Gabriela (Hospital Clínic i Provincial de Barcelona) ;
Bea, Sílvia (Hospital Clínic i Provincial de Barcelona) ;
Boldorini, Renzo (University of Eastern Piedmont, Novara, Italy) ;
Broccoli, Alessandro (IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy.) ;
Buehler, Marco Matteo (University Hospital Zurich, Switzerland) ;
Canzonieri, Vincenzo (Pathology Unit, CRO Aviano National Cancer Institute, Aviano, Italy) ;
Cascione, Luciano (Institute of Oncology Research, Bellinzona, Switzerland) ;
Ceriani, Luca (Clinic of Nuclear Medicine and PET-CT Centre, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Cogliatti, Sergio (Institute of Pathology, Kantonsspital St Gallen, St Gallen, Switzerland) ;
Corradini, Paolo (Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy) ;
Derenzini, Enrico (European Institute of Oncology (IEO) IRCCS, Milan, Italy) ;
Devizzi, Liliana (Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Italy) ;
Dietrich, Sascha (University Hospital Heidelberg, Germany) ;
Elia, Angela Rita (Institute of Oncology Research, Bellinzona, Switzerland) ;
Facchetti, Fabio (Pathology Unit, Spedali Civili, Brescia, Italy) ;
Gaidano, Gianluca (University of Eastern Piedmont, Novara, Italy) ;
Garcia, Juan Fernando (MD Anderson Cancer Center, Madrid) ;
Gerber, Bernhard (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Ghia, Paolo (IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy) ;
Gomes da Silva, Maria (Instituto Português de Oncologia de Lisboa, Portugal) ;
Gritti, Giuseppe (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy) ;
Guidetti, Anna (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Italy) ;
Hitz, Felicitas (Kantonsspital St Gallen, St Gallen, Switzerland) ;
Inghirami, Giorgio (Weill Cornell Medical College, New York) ;
Ladetto, Marco (Azienda Ospedaliera SS Antonio e Biagio, Alessandria, Italy) ;
Lopez-Guillermo, Armando (Hospital Clínic i Provincial de Barcelona) ;
Lucchini, Elisa (Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy) ;
Maiorana, Antonino (Universitá degli Studi di Modena e Reggio Emilia, Modena, Italy) ;
Marasca, Roberto (University of Modena and Reggio Emilia, Modena, Italy) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Meignin, Veronique (Saint Louis Hospital, Paris, France) ;
Merli, Michele (University of Insubria and ASST Sette Laghi, Ospedale di Circolo of Varese, Varese, Italy) ;
Moccia, Alden (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Mollejo, Manuela (Hospital Virgen de la Salud (Toledo)) ;
Montalban, Carlos (MD Anderson Cancer Center, Madrid) ;
Novak, Urban (University of Bern, Bern, Switzerland) ;
Oscier, David Graham (University Hospitals Dorset, Bournemouth, United Kingdom) ;
Passamonti, Francesco (University of Insubria) ;
Piazza, Francesco (Ospedale Universitario di Padova, Italy) ;
Pizzolitto, Stefano (General Hospital S Maria della Misericordia, Udine, Italy) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy) ;
Sabattini, Elena (University of Bologna, Italy) ;
Salles, Gilles (Université de Lyon, France) ;
Santambrogio, Elisa (Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy) ;
Scarfò, Lydia (IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy) ;
Stathis, Anastasios (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Stüssi, Georg (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Geyer, Julia T. (Weill Cornell Medical College, New York) ;
Tapia, G. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tarella, Corrado (European Institute of Oncology (IEO) IRCCS, Milan, Italy) ;
Thieblemont, Catherine (Université de Paris, France) ;
Tousseyn, Thomas (University Hospitals Leuven, Belgium) ;
Tucci, Alessandra (Spedali Civili, Brescia, Italy.) ;
Vanini, Giorgio (University of Bern, Switzerland) ;
Visco, Carlo (University of Verona, Italy) ;
Vitolo, Umberto (Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy) ;
Walewska, Renata (University Hospitals Dorset, Bournemouth, United Kingdom) ;
Zaja, Francesco (Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy) ;
Zenz, Thorsten (University Hospital Zurich, Switzerland) ;
Zinzani, Pier Luigi (Università di Bologna, Italy) ;
Khiabanian, Hossein (Rutgers University, New Brunswick) ;
Calcinotto, Arianna (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bertoni, Francesco (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bhagat, Govind (Columbia University, New York, USA) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
de Leval, Laurence (Institut Universitaire de Pathologie, Lausanne, Switzerland) ;
Dirnhofer, Stefan (University Hospital Basel (Basilea, Suïssa)) ;
Pileri, Stefano A. (European Institute of Oncology IRCCS, Milan, Italy) ;
Piris, Miguel Angel (Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Madrid) ;
Traverse-Glehen, Alexandra (Centre Hospitalier Lyon Sud, Lyon, France) ;
Tzankov, Alexander (University Hospital Basel (Basilea, Suïssa)) ;
Paulli, Marco (Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Italy) ;
Ponzoni, Maurilio (Ateneo Vita-Salute San Raffaele University and Pathology Unit San Raffaele Scientific Institute, Milan, Italy) ;
Mazzucchelli, Luca (antonal Institute of Pathology, Locarno, Switzerland) ;
Cavalli, Franco (Institute of Oncology Research, Bellinzona, Switzerland; and.) ;
Zucca, Emanuele (International Extranodal Lymphoma Study Group, Bellinzona, Switzerland) ;
Rossi, Davide (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Universitat Autònoma de Barcelona
Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity. The clinical course is variable, multiple genes are mutated with no unifying mechanism, and essential regulatory pathways and surrounding microenvironments are diverse. [...]
2022 - 10.1182/blood.2021012386
Blood, Vol. 139 Núm. 5 (february 2022) , p. 732-747
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10 p, 786.4 KB |
Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation : An EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine
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Giannotti, Federica (Saint-Antoine Hospital) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Shouval, Roni (Chaim Sheba Medical Center (Israel)) ;
Sanz, Jaime (Instituto de Salud Carlos III) ;
Arcese, William (Rome Transplant Network tor Vergatä) ;
Angelucci, Emanuele (Ospedale Policlinico San Martino) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santarone, Stella (Ospedale Civile) ;
Benedetto, Bruno (S.S.C.V.D Trapianto di Cellule Staminali A.O.U Citta della Salute e della Scienza di Torino) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII) ;
Saccardi, Riccardo (Azienda Ospedaliera Universitaria Careggi) ;
Blaise, Didier (Institut Paoli Calmettes) ;
Carella, Michele Angelo (IRCCS) ;
Rocha, Vanderson (Universidade de São Paulo) ;
Baron, Frederic (University of Liege) ;
Mohty, Mohamad (Hospital Saint- Antoine) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (Tel-Aviv University) ;
Universitat Autònoma de Barcelona
Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the setting of non-T cell depleted haploidentical stem cell transplantation (NTD-Haplo). [...]
2018 - 10.1186/s13045-018-0655-8
Journal of hematology & oncology, Vol. 11 Núm. 1 (30 2018) , p. 110
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6 p, 790.6 KB |
Breakthrough infections in MPN-COVID vaccinated patients
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Barbui, Tiziano (Papa Giovanni XXIII Hospital) ;
Carobbio, Alessandra (Papa Giovanni XXIII Hospital) ;
Ghirardi, Arianna (Papa Giovanni XXIII Hospital) ;
Iurlo, Alessandra (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
De Stefano, Valerio (Università Cattolica del Sacro Cuore) ;
Sobas, Marta Anna (Wroclaw Medical University) ;
Rumi, Elisa (University of Pavia) ;
Elli, Elena Maria (Ospedale San Gerardo (Itàlia)) ;
Lunghi, Francesca (IRCCS Ospedale San Raffaele) ;
Gasior Kabat, Mercedes (Hospital Universitario La Paz (Madrid)) ;
Cuevas, Beatriz (Hospital Universitario de Burgos) ;
Guglielmelli, Paola (University of Florence) ;
Bonifacio, Massimiliano (University of Verona (Itàlia)) ;
Marchetti, Monia (AOU SS.Antonio e Biagio e C.Arrigo, Alessandria, Italy) ;
Alvarez-Larran, Alberto (Hospital Clínic i Provincial de Barcelona) ;
Fox, Maria Laura (Vall d'Hebron Institut d'Oncologia) ;
Bellini, Marta (ASST Papa Giovanni XXIII) ;
Daffini, Rosa (ASST-Spedali Civili) ;
Benevolo, Giulia (AOU Città della Salute e della Scienza di Torino) ;
Carreño-Tarragona, Gonzalo (Hospital Universitario 12 de Octubre (Madrid)) ;
Patriarca, Andrea (AOU Maggiore della Carità (Itàlia)) ;
Al-Ali, Haifa Kathrin (University Hospital Halle) ;
Andrade-Campos, Marcio Miguel (Hospital del Mar (Barcelona, Catalunya)) ;
Palandri, Francesca (IRCCS Azienda Ospedaliero-Universitaria di Bologna) ;
Harrison, Claire (Guy's and St. Thomas' NHS Foundation Trust) ;
Foncillas, Maria Angeles (Hospital Universitario Infanta Leonor) ;
Osorio, Santiago (Hospital General Universitario Gregorio Marañón) ;
Koschmieder, Steffen (RWTH Aachen University) ;
Magro Mazo, Elena (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Kiladjian, Jean-Jacques (Hospital Saint-Louis) ;
Bolaños Calderón, Estefanía (Hospital Clínico San Carlos (Madrid)) ;
Heidel, Florian H. (University Medicine Greifswald - Hematology) ;
Quiroz Cervantes, Keina (Hospital Universitario de Móstoles (Madrid)) ;
Griesshammer, Martin (University Clinic for Hematology (Alemanya)) ;
Garcia-Gutierrez, Valentin (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Sanchez, Alberto Marin (Complejo Hospitalario Universitario de Albacete) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Lopez Abadia, Emma (Hospital General Universitario de Elche) ;
Carli, Giuseppe (Ospedale San Bortolo) ;
Sagues Serrano, Miguel (Hospital de Sant Joan Despí Moisès Broggi) ;
Kusec, Rajko (University Hospital Dubrava-School of Medicine University of Zagreb) ;
Xicoy, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Guenova, Margarita (National Specialised Hospital for Active Treatment of Hematological Diseases (Bulgària)) ;
Navas Elorza, Begona (Hospital Moncloa (Madrid)) ;
Angona, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Cichocka, Edyta (Nicolaus Copernicus Hospital (Polònia)) ;
Kulikowska de Nałęcz, Anna (Department of Hematology and Internal Diseases, State Hospital, Opole, Poland) ;
Cattaneo, Daniele (Università degli Studi di Milano) ;
Bucelli, Cristina (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Betti, Silvia (Università Cattolica del Sacro Cuore - Policlinico Universitario Agostino Gemelli IRCCS) ;
Borsani, Oscar (University of Pavia) ;
Cavalca, Fabrizio (Ospedale San Gerardo (Itàlia)) ;
Carbonell Curralo, Sara (Hospital Clínic i Provincial de Barcelona) ;
Curto-Garcia, Natalia (Guy's and St. Thomas' NHS Foundation Trust) ;
Benajiba, Lina (Hospital Saint-Louis) ;
Rambaldi, Alessandro (Università degli Studi di Milano) ;
Vannucchi, Alessandro Maria (University of Florence) ;
Universitat Autònoma de Barcelona
2022 - 10.1038/s41408-022-00749-8
Blood Cancer Journal, Vol. 12 (november 2022)
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9 p, 906.5 KB |
Real-world use of blinatumomab in adult patients with B-cell acute lymphoblastic leukemia in clinical practice : results from the NEUF study
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Boissel, Nicolas (Saint-Louis Hospital. Division of Hematology, EA3518 Saint-Louis Institute for Research) ;
Chiaretti, Sabina ("Sapienza" University. Hematology Department of Translational and Precision Medicine) ;
Papayannidis, Cristina (Institute of Hematology "Seràgnoli". IRCCS, Azienda Ospedaliero Universitaria di Bologna) ;
Ribera, Jose-Maria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Bassan, Renato (Complex Operative Unit of Hematology, dell'Angelo Hospital and Santissimi Giovanni and Paolo Hospital, Mestre and Venice, Venezia-Mestre, Italy) ;
Sokolov, Andrey N. (National Research Center for Hematology, Moscow) ;
Alam, Naufil (Amgen Ltd, Uxbridge, United Kingdom) ;
Brescianini, Alessandra (Amgen (Europe) GmbH, Rotkreuz, Switzerland) ;
Pezzani, Isabella (Amgen (Europe) GmbH, Rotkreuz, Switzerland) ;
Kreuzbauer, Georg (Amgen (Europe) GmbH, Rotkreuz, Switzerland) ;
Zugmaier, Gerhard (Amgen Research (Munich) GmbH, Munich, Germany) ;
Foà, Robin ("Sapienza" University. Hematology Department of Translational and Precision Medicine) ;
Rambaldi, Alessandro (University of Milan and Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII. Department of Oncology and Haematology)
This retrospective observational study (NEUF) included adult patients with B-cell acute lymphoblastic leukemia (B-cell ALL) who had received blinatumomab for the treatment of minimal residual disease-positive (MRD+) or relapsed/refractory (R/R) B-cell ALL via an expanded access program (EAP). [...]
2023 - 10.1038/s41408-022-00766-7
Blood Cancer Journal, Vol. 13 (january 2023)
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4 p, 973.0 KB |
Long-term follow-up of recovered MPN patients with COVID-19
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Barbui, Tiziano (Papa Giovanni XXIII Hospital) ;
Iurlo, Alessandra (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Masciulli, Arianna (Papa Giovanni XXIII Hospital) ;
Carobbio, Alessandra (Papa Giovanni XXIII Hospital) ;
Ghirardi, Arianna (Papa Giovanni XXIII Hospital) ;
Rossi, Giuseppe (Spedali Civili) ;
Harrison, Claire (Guy's and St. Thomas' NHS Foundation Trust) ;
Alvarez-Larran, Alberto (Hospital Clínic i Provincial de Barcelona) ;
Elli, Elena María (Ospedale San Gerardo (Itàlia)) ;
Kiladjian, Jean-Jaques (Hospital Saint-Louis) ;
Gasior Kabat, Mercedes (Hospital Universitario La Paz (Madrid)) ;
Marin Sanchez, Alberto (Complejo Hospitalario Universitario de Albacete) ;
Palandri, Francesca (IRCCS Azienda Ospedaliero-Universitaria di Bologna) ;
Andrade-Campos, Marcio Miguel (Hospital del Mar (Barcelona, Catalunya)) ;
Vannucchi, Alessandro Maria (University of Florence) ;
Carreño-Tarragona, Gonzalo (Hospital Universitario 12 de Octubre (Madrid)) ;
Papadopoulos, Petros (Hospital Clínico San Carlos (Madrid)) ;
Quiroz Cervantes, Keina (Hospital Universitario de Móstoles (Madrid)) ;
Foncillas, Maria Angeles (Hospital Universitario Infanta Leonor) ;
Fox, Maria Laura (Vall d'Hebron Institut d'Oncologia) ;
Sagues Serrano, Miguel (Hospital de Sant Joan Despí Moisès Broggi) ;
Rumi, Elisa (University of Pavia) ;
Osorio, Santiago (Hospital General Universitario Gregorio Marañón) ;
Benevolo, Giulia (AOU Città della Salute e della Scienza di Torino) ;
Patriarca, Andrea (AOU Maggiore della Carità) ;
Navas Elorza, Begoña (Hospital Moncloa) ;
Garcia-Gutierrez, Valentín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Magro Mazo, Elena (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Lunghi, Francesca (IRCCS Ospedale San Raffaele) ;
Bonifacio, Massimiliano (Ospedale Policlinico "G.B. Rossi". Borgo Roma) ;
De Stefano, Valerio (Fondazione Policlinico "A. Gemelli" IRCCS) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Lopez Abadia, Emma (Hospital General de Elche (Alicante)) ;
Angona, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Xicoy Cirici, Blanca (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ruggeri, Marco (Ospedale San Bortolo) ;
Koschmieder, Steffen (RWTH Aachen University) ;
Sobas, Marta Anna (Wroclaw Medical University) ;
Cuevas, Beatriz (Hospital Universitario de Burgos) ;
Cattaneo, Daniele (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Daffini, Rosa (Spedali Civili) ;
Bellini, Marta (ASST Papa Giovanni XXIII) ;
Curto-Garcia, Natalia (Guy's and St. Thomas' NHS Foundation Trust) ;
Garrote, Marta (Hospital Clínic i Provincial de Barcelona) ;
Cavalca, Fabrizio (Hematology Division and Bone Marrow Transplant Unit. San Gerardo Hospital. ASST Monza) ;
Benajiba, Lina (Hospital Saint-Louis) ;
Bellosillo Paricio, Beatriz (Hospital del Mar (Barcelona, Catalunya)) ;
Guglielmelli, Paola (University of Florence) ;
Borsani, Oscar (University of Pavia) ;
Betti, Silvia (Fondazione Policlinico "A. Gemelli" IRCCS) ;
Salmoiraghi, Silvia (ASST Papa Giovanni XXIII) ;
Rambaldi, Alessandro (Università degli Studi di Milano) ;
Universitat Autònoma de Barcelona
2021 - 10.1038/s41408-021-00509-0
Blood Cancer Journal, Vol. 11 Núm. 6 (june 2021) , p. 115
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7 p, 820.3 KB |
Blinatumomab for Acute Lymphoblastic Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
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Stein, A. S. (Gehr Family Center for Leukemia Research. City of Hope) ;
Kantarjian, H. (The University of Texas M.D. Anderson Cancer Center) ;
Gökbuget, N. (Department of Medicine II. Goethe University) ;
Bargou, R. C. (Comprehensive Cancer Center Mainfranken. University Hospital Würzburg) ;
Litzow, Mark R (Mayo Clinic) ;
Rambaldi, Alessandro (Department of Oncology and Hemato-Oncology. University of Milan and Azienda Pope John XXIII Hospital) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Zhang, A. (Amgen Inc.) ;
Zimmerman, Z. (Amgen Inc.) ;
Zugmaier, Gerhard (Amgen Research Munich) ;
Topp, M. S. (Medical Clinic and Polyclinic II. University Hospital Würzburg) ;
Universitat Autònoma de Barcelona
Patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) following allogeneic hematopoietic stem cell transplantation (alloHSCT) have a poor prognosis, and alternative therapies are needed for this patient population. [...]
2019 - 10.1016/j.bbmt.2019.04.010
Biology of blood and marrow transplantation, Vol. 25 Núm. 8 (august 2019) , p. 1498-1504
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11 p, 1.4 MB |
Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19
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Barbui, Tiziano (Papa Giovanni XXIII Hospital. FROM Research Foundation) ;
De Stefano, Valerio (Fondazione Policlinico "A. Gemelli" IRCCS. Section of Hematology, Department of Radiological and Hematological Sciences, Catholic University) ;
Alvarez-Larran, Alberto (Hospital Clínic i Provincial de Barcelona) ;
Iurlo, Alessandra (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico. Hematology Division) ;
Masciulli, Arianna (Papa Giovanni XXIII Hospital. FROM Research Foundation) ;
Carobbio, Alessandra (Papa Giovanni XXIII Hospital. FROM Research Foundation) ;
Ghirardi, Arianna (Papa Giovanni XXIII Hospital. FROM Research Foundation) ;
Ferrari, Alberto (Papa Giovanni XXIII Hospital. FROM Research Foundation) ;
Cancelli, Valeria (Spedali Civili) ;
Elli, Elena Maria (Ospedale San Gerardo (Itàlia)) ;
Andrade-Campos, Marcio Miguel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kabat, Mercedes Gasior (Hospital Universitario La Paz (Madrid)) ;
Kiladjian, Jean-Jaques (Hospital Saint-Louis) ;
Palandri, Francesca (Azienda Ospedaliero-Universitaria di Bologna) ;
Benevolo, Giulia (AOU Città della Salute e della Scienza di Torino) ;
Garcia-Gutierrez, Valentin (Hospital Universitario Ramón y Cajal (Madrid)) ;
Fox, Maria Laura (Vall d'Hebron Institut d'Oncologia) ;
Foncillas, Maria Angeles (Hospital Universitario Infanta Leonor) ;
Morcillo, Carmen Montoya (Complejo Hospitalario Universitario de Albacete) ;
Rumi, Elisa (University of Pavia. Department of molecular medicine) ;
Osorio, Santiago (Hospital General Universitario Gregorio Marañón) ;
Papadopoulos, Petros (Hospital Clínico San Carlos (Madrid)) ;
Bonifacio, Massimiliano (Ospedale Policlinico "G.B. Rossi", Borgo Roma) ;
Quiroz Cervantes, Keina (Hospital Universitario de Móstoles (Madrid)) ;
Serrano, Miguel Sagues (Hospital de Sant Joan Despí Moisès Broggi) ;
Carreño-Tarragona, Gonzalo (Hospital Universitario 12 de Octubre (Madrid)) ;
Sobas, Marta Anna (Wroclaw Medical University. Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation) ;
Lunghi, Francesca (IRCCS Ospedale San Raffaele) ;
Patriarca, Andrea (AOU Maggiore della Carità, Novara, Italy) ;
Elorza, Begoña Navas (Hospital Moncloa, Madrid, Spain) ;
Angona, Anna (Hospital Universitari de Girona Doctor Josep Trueta) ;
Mazo, Elena Magro (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Koschmieder, Steffen (RWTH Aachen University. Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine) ;
Carli, Giuseppe (Ospedale San Bortolo) ;
Cuevas, Beatriz (Hospital Universitario de Burgos) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Abadia, Emma Lopez (Hospital General Universitario de Elche) ;
Xicoy, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Guglielmelli, Paola (University of Florence. Center Research and Innovation of Myeloproliferative Neoplasms (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi) ;
Garrote, Marta (Hospital Clínic i Provincial de Barcelona) ;
Cattaneo, Daniele (Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico. Hematology Division) ;
Daffini, Rosa (Spedali Civili) ;
Cavalca, Fabrizio (Ospedale San Gerardo (Itàlia)) ;
Bellosillo Paricio, Beatriz (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Benajiba, Lina (Hospital Saint-Louis) ;
Curto-Garcia, Natalia (Guy's and St. Thomas' NHS Foundation Trust) ;
Bellini, Marta (ASST Papa Giovanni XXIII, Bergamo, Italy) ;
Betti, Silvia (Fondazione Policlinico "A. Gemelli" IRCCS. Section of Hematology, Department of Radiological and Hematological Sciences, Catholic University) ;
Harrison, Claire (Guy's and St. Thomas' NHS Foundation Trust) ;
Rambaldi, Alessandro (Università degli Studi di Milano) ;
Vannucchi, Alessandro Maria (University of Florence. Center Research and Innovation of Myeloproliferative Neoplasms (CRIMM), Department of Experimental and Clinical Medicine, Azienda Ospedaliera Universitaria Careggi) ;
Universitat Autònoma de Barcelona
In a multicenter European retrospective study including 162 patients with COVID-19 occurring in essential thrombocythemia (ET, n = 48), polycythemia vera (PV, n = 42), myelofibrosis (MF, n = 56), and prefibrotic myelofibrosis (pre-PMF, n = 16), 15 major thromboses (3 arterial and 12 venous) were registered in 14 patients, of whom all, but one, were receiving LMW-heparin prophylaxis. [...]
2021 - 10.1038/s41408-021-00417-3
Blood Cancer Journal, Vol. 11 (february 2021)
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Blinatumomab compared with standard of care for the treatment of adult patients with relapsed/refractory Philadelphia chromosome-positive B-precursor acute lymphoblastic leukemia
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Rambaldi, Alessandro (Department of Oncology and Hematology. University of Milan) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Kantarjian, H. M. (Department of Leukemia. University of Texas MD Anderson Cancer Center) ;
Dombret, Hervé (Department of Hematology. Hopital Saint-Louis. Paris Diderot University) ;
Ottmann, O. G. (Division of Cancer and Genetics. School of Medicine. Cardiff University) ;
Stein, A. S. (Gehr Family Center for Leukemia Research. City of Hope) ;
Tuglus, C. A. (Amgen. Inc) ;
Zhao, X. (Amgen. Inc) ;
Kim, C. (Amgen. Inc) ;
Martinelli, Giovanni (Scientific Institute of Romagna for the Study and Treatment of Cancer) ;
Universitat Autònoma de Barcelona
Background: A single-arm, phase 2 trial demonstrated the efficacy and safety of blinatumomab, a bispecific T-cell-engaging antibody construct, in patients with relapsed/refractory (r/r) Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL), a rare hematologic malignancy with limited treatment options. [...]
2020 - 10.1002/cncr.32558
Cancer, Vol. 126 Núm. 2 (15 2020) , p. 304-310
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13 p, 2.7 MB |
Minimal residual disease level predicts outcome in adults with Ph-negative Bprecursor acute lymphoblastic leukemia
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Gökbuget, Nicola (University Hospital of Frankfurt (Alemanya)) ;
Dombret, Hervé (Hôpital Saint-Louis, Université Paris Diderot) ;
Giebel, Sebastian (Maria Sklodowska Curie Memorial Cancer Center, Gliwice) ;
Bruggemann, Monika (Universitätsklinikum Schleswig-Holstein (Alemanya)) ;
Doubek, Michael (University Hospital Brno (República Txeca)) ;
Foà, Robin (Sapienza University of Rome) ;
Hoelzer, Dieter (University Hospital of Frankfurt (Alemanya)) ;
Kim, Christopher (Amgen Inc, Thousand Oaks, CA, USA) ;
Martinelli, Giovanni (Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS) ;
Parovichnikova, Elena (National Research Center for Hematology, Moscow) ;
Rambaldi, Alessandro (Dipartimento di Oncologia ed Ematologia, Università degli Studi di Milano and Ospedale Papa Giovanni XXIII) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Schoonen, Marieke (Amgen Ltd, London) ;
Stieglmaier, Julia M. (Amgen GmBH, Munich) ;
Zugmaier, Gerhard (Amgen GmBH, Munich) ;
Bassan, Renato (Ospedale dell'Angelo, Mestre-Venezia) ;
Universitat Autònoma de Barcelona
Objectives: Detectable minimal residual disease (MRD) after therapy for acute lymphoblastic leukemia (ALL) is the strongest predictor of hematologic relapse. This study evaluated outcomes of patients with B-cell precursor ALL with MRD of ≥10−4. [...]
2019 - 10.1080/16078454.2019.1567654
Hematology, Vol. 24 Núm. 1 (2019) , p. 337-348
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