Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.01 segons. 
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12 p, 2.4 MB Mutations at the hydrophobic core affect Hal3 trimer stability, reducing its Ppz1 inhibitory capacity but not its PPCDC moonlighting function / Santolaria Bello, Carlos (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Velázquez, Diego (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Strauss, Erick (Stellenbosch University. Department of Biochemistry) ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
S. cerevisiae Hal3 (ScHal3) is a moonlighting protein that, is in its monomeric state, regulates the Ser/Thr protein phosphatase Ppz1, but also joins ScCab3 (and in some instances the Hal3 paralog Vhs3) to form an unusual heterotrimeric phosphopantothenoylcysteine decarboxylase (PPCDC) enzyme. [...]
2018 - 10.1038/s41598-018-32979-x
Scientific reports (Nature Publishing Group), Vol. 8 (2018) , art. 14701  
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17 p, 1.6 MB Complex stability and dynamic subunit interchange modulates the disparate activities of the yeast moonlighting proteins Hal3 and Vhs3 / Abrie, J. Albert (Stellenbosch University. Department of Biochemistry) ; Molero Merinero, Cristina (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Strauss, Erick (Stellenbosch University. Department of Biochemistry) ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Saccharomyces cerevisiae Hal3 and Vhs3 are moonlighting proteins, acting both as inhibitors of the serine/threonine protein phosphatase Ppz1 and as subunits (together with Cab3) of the unique heterotrimeric phosphopantothenoylcysteine decarboxylase (PPCDC) enzyme of Hemiascomycetous yeast. [...]
2015 - 10.1038/srep15774
Scientific reports (Nature Publishing Group), Vol. 5 (October 2015) , art. 15774  
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32 p, 2.8 MB Moonlighting Proteins Hal3 and Vhs3 Form a Heteromeric PPCDC with Ykl088w in Yeast CoA Biosynthesis / Ruiz, Amparo (Universitat Autonòma de Barcelona. Departament de Bioquimica i Biologia Molecular) ; González Seviné, Asier (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Muñoz, Ivan (Universitat Autonòma de Barcelona. Departament de Bioquimica i Biologia Molecular) ; Serrano Cánovas, Raquel (Universitat Autonòma de Barcelona. Departament de Bioquimica i Biologia Molecular) ; Abrie, J. Albert (Stellenbosch University (South Africa). Department of Biochemistry) ; Strauss, Erick (Stellenbosch University (South Africa). Department of Biochemistry) ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Unlike most other organisms, the essential five-step Coenzyme A biosynthetic pathway has not been fully resolved in yeast. Specifically, the gene(s) encoding the phosphopantothenoylcysteine decarboxylase (PPCDC) activity still remains unidentified. [...]
2009 - 10.1038/nchembio.243
Nature chemical biology, Vol. 5, Núm. 12 (2009) , p. 920-928  

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