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11.
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14 p, 236.7 KB |
Clinical Variables and Genetic Risk Factors Associated with the Acute Outcome of Ischemic Stroke : A Systematic Review
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Torres-Aguila, Nuria P.. (Institut d'Investigació Biomèdica Sant Pau) ;
Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ;
Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Cullell, Natalia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
González-Sánchez, Jonathan (Institut d'Investigació Biomèdica Sant Pau) ;
Bustamante, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ibañez, Laura (Washington University School of Medicine. Department of Psychiatry) ;
Heitsch, Laura (Washington University School of Medicine. Department of Neurology) ;
Krupinski, Jerzy (The Manchester Metropolitan University of All Saints. Health Care Science Department) ;
Montaner, Joan (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Cruchaga, Carlos (Washington University School of Medicine. Department of Psychiatry) ;
Lee, Jin-Moo (Washington University School of Medicine. Department of Neurology) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Stroke is a complex disease and one of the main causes of morbidity and mortality among the adult population. A huge variety of factors is known to influence patient outcome, including demographic variables, comorbidities or genetics. [...]
2019 -  10.5853/jos.2019.01522
Journal of Stroke, Vol. 21 (september 2019) , p. 276-289
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12.
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28 p, 504.2 KB |
Action Plan for Stroke in Europe 2018-2030
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Norrving, Bo (Lund University. Department of Clinical Sciences) ;
Barrick, Jon (Stroke Alliance for Europe) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dichgans, Martin (Ludwig-Maximilians University) ;
Cordonnier, Charlotte (CHU Lille. Department of Neurology) ;
Guekht, Alla (Russian National Research Medical University) ;
Kutluk, Kursad (University of Dokuz Eylul. Department of Neurology) ;
Mikulik, Robert (Masaryk University) ;
Wardlaw, Joanna (University of Edinburgh) ;
Richard, Edo (Radboud University Medical Centre) ;
Nabavi, Darius (Vivantes Hospital Neukölln) ;
Molina, Carlos (Hospital Universitari Vall d'Hebron) ;
Bath, P. M. W (University of Nottingham) ;
Stibrant Sunnerhagen, Katharina (Sahlgrenska University Hospital (Suècia)) ;
Rudd, Anthony (Guy's and St Thomas' NHS Foundation Trust) ;
Drummond, Avril (School of Health Sciences, University of Nottingham) ;
Planas, Anna Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Caso, Valeria (University of Perugia. Department of Medicine and Cardiovascular Medicine) ;
Universitat Autònoma de Barcelona
Two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg meetings, were convened to review the scientific evidence and the state of current services to identify priorities for research and development and to set targets for the development of stroke care for the decade to follow. [...]
2018 - 10.1177/2396987318808719
European Stroke Journal, Vol. 3 Núm. 4 (october 2018) , p. 309-336
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13.
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6 p, 525.3 KB |
Long-Term Stroke Recurrence after Transient Ischemic Attack : Implications of Etiology
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Ois, Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cuadrado-Godia, Elisa (Hospital del Mar (Barcelona, Catalunya)) ;
Giralt Steinhauer, Eva (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Soriano-Tarraga, Carolina (Hospital del Mar (Barcelona, Catalunya)) ;
Rodríguez Campello, Ana (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Avellaneda-Gómez, C (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cascales, Diego (Hospital del Mar (Barcelona, Catalunya)) ;
Fernandez-Perez, Isabel (Hospital del Mar (Barcelona, Catalunya)) ;
Roquer, Jaume (Hospital del Mar (Barcelona, Catalunya))
To analyze long-term stroke recurrence (SR) characteristics after transient ischemic attack (TIA) according to initial etiological classification. A prospective cohort of 706 TIA patients was followed up in a single tertiary stroke center. [...]
2019 - 10.5853/jos.2018.03601
Journal of Stroke, Vol. 21 (april 2019) , p. 184-189
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14.
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20 p, 1.7 MB |
Timing of Recanalization and Functional Recovery in Acute Ischemic Stroke
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Tsivgoulis, Georgios (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Saqqur, Maher (Department of Neuroscience, Hamad General Hospital, Doha) ;
Sharma, Vijay K. (Division of Neurology, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore) ;
Brunser, Alejandro (Department of Emergency Medicine, Clinica Alemana of Santiago, University of Desarrollo, Santiago) ;
Eggers, Jürgen (Department of Neurology, Sana Hospital Lubeck, Lübeck) ;
Mikulik, Robert (Medical Faculty, Masaryk University, Brno) ;
Katsanos, Aristeidis H. (Department of Neurology, University of Ioannina School of Medicine, Ioannina) ;
Sergentanis, Theodore N. (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Vadikolias, Konstantinos (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Perren, Fabienne (Geneva University Hospitals (Suïssa)) ;
Rubiera Del Fueyo, Marta A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bavarsad Shahripour, Reza (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Nguyen, Huy Thang (Department of Cerebrovascular Disease, 115 The People Hospital, Ho Chi Minh) ;
Martínez-Sánchez, Patricia (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Safouris, Apostolos (Stroke Unit, Department of Neurology, Brugmann University Hospital, Brussels) ;
Heliopoulos, Ioannis (Department of Neurology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis) ;
Shuaib, Ashfaq (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Derksen, Carol (Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB) ;
Voumvourakis, Konstantinos (University General Hospital Attikon (Haidari, Grècia)) ;
Psaltopoulou, Theodora (Department of Hygiene, Epidemiology, and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens) ;
Alexandrov, Andrei V (Department of Neurology, University of Tennessee Health Science Center, Memphis, TN) ;
Alexandrov, Andrei V. (Department of Neurology, University of Alabama at Birmingham, Birmingham, AL) ;
Universitat Autònoma de Barcelona
Although onset-to-treatment time is associated with early clinical recovery in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (tPA), the effect of the timing of tPA-induced recanalization on functional outcomes remains debatable. [...]
2020 - 10.5853/jos.2019.01648
Journal of Stroke, Vol. 22 (january 2020) , p. 130-140
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15.
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9 p, 267.6 KB |
Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial
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van der Worp, H. B. (Department of Neurology and Neurosurgery. Brain Center. University Medical Center Utrecht) ;
Macleod, Malcolm R. (Centre for Clinical Brain Sciences. University of Edinburgh) ;
Bath, P. M. W. (Stroke Trials Unit. Division of Clinical Neuroscience. University of Nottingham) ;
Bathula, R. (Stroke Department. Northwick Park Hospital) ;
Christensen, Hanne (University of Copenhagen) ;
Colam, B. (Centre for Clinical Brain Sciences. University of Edinburgh) ;
Cordonnier, Charlotte (University of Lille. Inserm U1171. Degenerative and Vascular Cognitive Disorders. Centre Hospitalier Universitaire Lille) ;
Demotes-Mainard, J. (ECRIN) ;
Durand-Zaleski, I. (APHP URCEco. University Paris Est Creteil & INSERM. UMR 1123) ;
Gluud, C. (Copenhagen Trial Unit. Centre for Clinical Intervention Research. Rigshospitalet. Copenhagen University Hospital) ;
Jakobsen, J. C. (Holbæk Hospital (Dinamarca)) ;
Kallmünzer, B. (Department of Neurology. University Medical Centre Erlangen) ;
Kollmar, R. (Klinik für Neurologie und Neurointensivmedizin. Klinikum Darmstadt) ;
Krieger, D. W. (Mediclinic Middle East) ;
Lees, K. R. (School of Medicine. Dentistry & Nursing. University of Glasgow) ;
Michalski, D. (Department of Neurology. University of Leipzig) ;
Molina, Carlos (Hospital Universitari Vall d'Hebron) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roine, R. O. (Turku University Hospital (Finlàndia)) ;
Petersson, J. (Skåne University Hospital (Suècia)) ;
Perry, Richard (Stroke Service. National Hospital for Neurology & Neurosurgery) ;
Sprigg, N. (Stroke Trials Unit. Division of Clinical Neuroscience. University of Nottingham) ;
Staykov, D. (Department of Neurology. Hospital of the Brothers of St. John) ;
Szabo, I. (European Stroke Research Network for Hypothermia) ;
Vanhooren, G. (AZ Sint-Jan Brugge-Oostende) ;
Wardlaw, J. M. (Edinburgh Imaging. Centre for Clinical Brain Sciences. UK Dementia Research Institute. University of Edinburgh) ;
Winkel, P. (Copenhagen Trial Unit. Centre for Clinical Intervention Research. Rigshospitalet. Copenhagen University Hospital) ;
Schwab, S. (Department of Neurology. University Medical Centre Erlangen) ;
Universitat Autònoma de Barcelona
Introduction: We assessed whether modest systemic cooling started within 6 hours of symptom onset improves functional outcome at three months in awake patients with acute ischaemic stroke. Patients and methods: In this European randomised open-label clinical trial with blinded outcome assessment, adult patients with acute ischaemic stroke were randomised to cooling to a target body temperature of 34. [...]
2019 - 10.1177/2396987319844690
European Stroke Journal, Vol. 4 Núm. 3 (january 2019) , p. 254-262
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15 p, 517.3 KB |
GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke
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Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Nafría, Cristina (Hospital Universitari Vall d'Hebron) ;
Garcia, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Carrera, Caty (Hospital Universitari Vall d'Hebron) ;
Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mútua Terrassa) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Castellanos, María del Mar (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo, Mari Mar (Hospital de Basurto (Bilbao, Biscaia)) ;
Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Rubiera, Marta (Hospital Universitari Vall d'Hebron) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Font, Maria Angels (Hospital Universitari de Bellvitge) ;
Grau Olivares, Marta (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Palomeras, Ernest (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez Zabaleta, Maite (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Masjuan, Jaime (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moniche, Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Piñana, Carlos (Hospital Universitario Virgen de las Nieves (Granada)) ;
Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Cocho, Dolores (Hospital General de Granollers) ;
Navas, Inma (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Tejero, Carlos (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Aymerich, Nuria (Complejo Hospitalario de Navarra) ;
Cullell, Natalia (Fundació Docència i Recerca Mútua Terrassa) ;
Muiño, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubio, Francisco (Hospital Universitari de Bellvitge) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Keene, Keith (Center for Health Disparities. East Carolina University) ;
Chen, Wei-Min (University of Virginia) ;
Worrall, Bradford (University of Virginia) ;
Sale, Michele (Center for Public Health Genomics, University of Virginia) ;
Arboix, Adrià (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron) ;
GRECOSstudy group ;
Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153
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9 p, 561.3 KB |
Benefits of Emergency Departments' Contribution to Stroke Prophylaxis in Atrial Fibrillation
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Coll-Vinent, Blanca (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martín, Alfonso (Spanish Society of Emergency Medicine (SEMES)) ;
Sánchez, Juan (Spanish Society of Emergency Medicine (SEMES)) ;
Tamargo, Juan (Universidad Complutense de Madrid) ;
Suero, Coral (Spanish Society of Emergency Medicine (SEMES)) ;
Malagón, Francisco (Spanish Society of Emergency Medicine (SEMES)) ;
Varona, Mercedes (Spanish Society of Emergency Medicine (SEMES)) ;
Cancio, Manuel (Spanish Society of Emergency Medicine (SEMES)) ;
Sánchez, Susana (Spanish Society of Emergency Medicine (SEMES)) ;
Carbajosa, José (Spanish Society of Emergency Medicine (SEMES)) ;
Ríos, José (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Casanovas Mateu, Georgina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ràfols, Carles (Spanish Society of Emergency Medicine (SEMES)) ;
del Arco, Carmen (Spanish Society of Emergency Medicine (SEMES))
Supplemental Digital Content is available in the text. Long-term benefits of initiating stroke prophylaxis in the emergency department (ED) are unknown. We analyzed the long-term safety and benefits of ED prescription of anticoagulation in atrial fibrillation patients. [...]
2017 - 10.1161/STROKEAHA.116.014855
Stroke, Vol. 48 (april 2017) , p. 1344-1352
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18.
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9 p, 730.3 KB |
Safety and Efficacy of Solitaire Stent Thrombectomy
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Campbell, Bruce C.V ;
Hill, M. D ;
Rubiera Del Fueyo, Marta A ;
Menon, Bijoy K. ;
Demchuk, Andrew ;
Donnan, Geoffrey A. ;
Roy, Daniel ;
Thornton, John ;
Dorado Bouix, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bonafe, Alain ;
Levy, Elad I. ;
Diener, Hans-Christoph ;
Hernández-Pérez, María ;
Pereira, Vitor Mendes ;
Blasco, Jordi ;
Quesada, Helena ;
Rempel, Jeremy ;
Jahan, Reza ;
Davis, Stephen M. ;
Stouch, Bruce C. ;
Mitchell, Peter J. ;
Jovin, Tudor G. ;
Saver, Jeffrey L.. ;
Goyal, Mayank ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is available in the text. Patient-level data were pooled from trials in which the Solitaire was the only or the predominant device used in a prespecified meta-analysis (SEER Collaboration): Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME), Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times (ESCAPE), Extending the Time for Thrombolysis in Emergency Neurological Deficits-Intra-Arterial (EXTEND-IA), and Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset (REVASCAT). [...]
2016 - 10.1161/STROKEAHA.115.012360
Stroke, Vol. 47 (february 2016) , p. 798-806
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10 p, 562.8 KB |
Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients
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Nafría, Cristina. (Hospital Universitari Vall d'Hebron) ;
Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendioroz, Maite (Hospital Universitari Vall d'Hebron) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Hernandez Guillamon, Maria Mar (Hospital Universitari Vall d'Hebron) ;
Fernández-Morales, Jessica (Hospital Universitari Vall d'Hebron) ;
Río-Espínola, Alberto del (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Deu, L. (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ;
Rosell, A. (Hospital Universitari Vall d'Hebron) ;
Montaner, J. (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
An accurate understanding of the mechanisms underlying an individual's response to rt-PA treatment is critical to improve stroke patients' management. We thus reviewed the literature in order to identify biochemical and genetic factors that have been associated with safety and efficacy of rt-PA administration after stroke.
2011 - 10.4061/2011/182783
Stroke Research and Treatment, Vol. 2011 (june 2011)
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