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15 p, 3.9 MB A Transcriptome Analysis : Various Reasons of Adverse Pregnancy Outcomes Caused by Acute Toxoplasma gondii Infection / Zhou, Xue (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs) ; Zhang, Xiu-Xiang (South China Agricultural University. College of Agriculture) ; Mahmmod, Yasser (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ; Hernandez, Jorge A. (University of Florida. College of Veterinary Medicine) ; Li, Gui-Feng (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs) ; Huang, Wan-Yi (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs) ; Wang, Ya-Pei (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs) ; Zheng, Yu-Xiang (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs) ; Li, Xiu-Ming (Heilongjiang Bayi Agricultural University. College of Animal Science and Technology) ; Yuan, Zi-Guo (South China Agricultural University. Key Laboratory of Zoonosis of Ministry of Agriculture and Rural Affairs)
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite, which can affect the pregnancy outcomes in infected females by damaging the uterus, and the intrauterine environment as well as and the hypothalamus resulting in hormonal imbalance. [...]
2020 - 10.3389/fphys.2020.00115
Frontiers in physiology, Vol. 11 (february 2020)  
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11 p, 1.6 MB Transcriptomic analysis of reproductive damage in the epididymis of male Kunming mice induced by chronic infection of Toxoplasma gondii PRU strain / Zheng, Yu-Xiang (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province) ; Zhang, Xiu-Xiang (South China Agricultural University. College of Plant) ; Hernandez, Jorge A. (University of Florida. College of Veterinary Medicine) ; Mahmmod, Yasser (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ; Huang, Wan Yi (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province) ; Li, Gui-Feng (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province) ; Wang, Ya-Pei. (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province) ; Zhou, Xue (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province) ; Li, Xiu-Ming (Heilongjiang BaYi Agricultural University. College of Animal Science and Technology) ; Yuan, Zi-Guo (Key Laboratory of Zoonosis Prevention and Control of Guangdong Province)
According to results of a bioinformatics analysis, Gene Ontology (GO) function is divided into three categories: Cellular component, molecular function and biological process. Upon performing GO analysis, we found that some DEGs correlated with an integral part of membrane, protein complex, cell surface, ATP binding, immune system process, signal transduction and metabolic process which are responsible for the epididymal injury. [...]
Background: Some researchers have reported that Toxoplasma gondii can cause serious reproductive impairment in male animals. Specifically, T. gondii destroy the quality of sperm in the epididymis, which affects their sexual ability. [...]

2019 - 10.1186/s13071-019-3783-2
Parasites & vectors, Vol. 12 Núm. 1 (august 2019) , p. 529  

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2 Zhou, X.
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1 Zhou, Xuancheng
1 Zhou, Xudong
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