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1.
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9 p, 1.3 MB |
Longitudinal deep learning clustering of Type 2 Diabetes Mellitus trajectories using routinely collected health records
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Manzini, Enrico (Institut de Recerca Sant Joan de Déu) ;
Vlacho, Bogdan (DAP-Cat Group. Unitat de Suport a la Recerca. Fundaciò Institut Universitari per a la recerca a l'Atenciò Primària de Salut Jordi Gol i Gurina (IDIAPJGol)) ;
Franch-Nadal, Josep (Primary Health Care Center Raval Sud. Institut Català de la Salut) ;
Escudero, J. (Grupo Pulso) ;
Génova, A. (Grupo Pulso) ;
Reixach, Elisenda (Fundació TIC Salut Social. Departament de Salut. Generalitat de Catalunya) ;
Andrés, E. (Fundació TIC Salut Social. Departament de Salut. Generalitat de Catalunya) ;
Pizarro, I. (Novo Nordisk) ;
Portero, J.L. (Novo Nordisk) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Perera Lluna, Alexandre (Institut de Recerca Sant Joan de Déu)
Type 2 diabetes mellitus (T2DM) is a highly heterogeneous chronic disease with different pathophysiological and genetic characteristics affecting its progression, associated complications and response to therapies. [...]
2022 -  10.1016/j.jbi.2022.104218
Journal of Biomedical Informatics, Vol. 135 (november 2022) , p. 104218
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2.
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14 p, 2.9 MB |
HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
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Brochado Kith, Óscar (Instituto de Salud Carlos III) ;
Martínez, Isidoro (Instituto de Salud Carlos III) ;
Berenguer, Juan (Hospital General Universitario Gregorio Marañón) ;
Medrano, Luz María (Instituto de Salud Carlos III) ;
González-García, Juan (Hospital Universitario La Paz (Madrid)) ;
Jiménez-Sousa, María Ángeles (Instituto de Salud Carlos III) ;
Carrero, Ana (Hospital General Universitario Gregorio Marañón) ;
Hontañón Antoñana, Víctor (Hospital Universitario La Paz (Madrid)) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guardiola Tey, Jose Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández-Rodríguez, Amanda (Instituto de Salud Carlos III) ;
Resino, Salvador (Instituto de Salud Carlos III) ;
Miralles, P. (GESIDA Study Group) ;
López, J.C. (GESIDA Study Group) ;
Parras, F. (GESIDA Study Group) ;
Padilla, B. (GESIDA Study Group) ;
Aldámiz-Echevarría, T (GESIDA Study Group) ;
Tejerina, F. (GESIDA Study Group) ;
Díez, C. (GESIDA Study Group) ;
Pérez-Latorre, L. (GESIDA Study Group) ;
Fanciulli, C. (GESIDA Study Group) ;
Gutiérrez, I. (GESIDA Study Group) ;
Ramírez, M. (GESIDA Study Group) ;
Carretero, S. (GESIDA Study Group) ;
Bellón, José-María (GESIDA Study Group) ;
Bermejo, Javier (GESIDA Study Group) ;
Arribas, Jose (GESIDA Study Group) ;
Montes, M.L. (GESIDA Study Group) ;
Bernardino, I. (GESIDA Study Group) ;
Pascual, J.F. (GESIDA Study Group) ;
Zamora, Francisco (GESIDA Study Group) ;
Peña, J.M. (GESIDA Study Group) ;
Arnalich, F. (GESIDA Study Group) ;
Díaz, M. (GESIDA Study Group) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Van den Eynde, E. (Hospital Universitari Vall d'Hebron) ;
Pérez, M. (GESIDA Study Group) ;
Ribera, E. (Hospital Universitari Vall d'Hebron) ;
Crespo Casal, Manuel (Hospital Universitari Vall d'Hebron) ;
Casado, José Luis (GESIDA Study Group) ;
Dronda, F. (GESIDA Study Group) ;
Moreno, A. (GESIDA Study Group) ;
Pérez-Elías, M.J. (GESIDA Study Group) ;
Sanfrutos, M.A. (GESIDA Study Group) ;
Moreno, S. (GESIDA Study Group) ;
Quereda, C. (GESIDA Study Group) ;
Arranz, A. (GESIDA Study Group) ;
Casas, E. (GESIDA Study Group) ;
de Miguel, J. (GESIDA Study Group) ;
Schroeder, S. (GESIDA Study Group) ;
Sanz, J. (GESIDA Study Group) ;
Santos, I. (GESIDA Study Group) ;
Bustinduy, M.J. (GESIDA Study Group) ;
Iribarren, J.A. (GESIDA Study Group) ;
Rodríguez-Arrondo, F. (GESIDA Study Group) ;
Von-Wichmann, M.A. (GESIDA Study Group) ;
Vergas, J. (GESIDA Study Group) ;
Téllez, M.J. (GESIDA Study Group) ;
Vinuesa, D. (GESIDA Study Group) ;
Muñoz, L. (GESIDA Study Group) ;
Hernández-Quero, J. (GESIDA Study Group) ;
Ferrer, A. (GESIDA Study Group) ;
Galindo, María José (GESIDA Study Group) ;
Ortiz, L. (GESIDA Study Group) ;
Ortega, E. (GESIDA Study Group) ;
Montero, M. (GESIDA Study Group) ;
Blanes, M. (GESIDA Study Group) ;
Cuellar, S. (GESIDA Study Group) ;
Lacruz, J. (GESIDA Study Group) ;
Salavert, M. (GESIDA Study Group) ;
López-Aldeguer, J. (GESIDA Study Group) ;
Pérez, G. (GESIDA Study Group) ;
Gaspar, G. (GESIDA Study Group) ;
Yllescas, M. (GESIDA Study Group) ;
Crespo, P. (GESIDA Study Group) ;
Aznar, E. (GESIDA Study Group) ;
Esteban, H. (GESIDA Study Group)
Objective: To evaluate the impact of hepatitis C virus (HCV) elimination via interferon (IFN)-based therapy on gene expression profiles related to the immune system in HIV/HCV-coinfected patients. Methods: We conducted a prospective study in 28 HIV/HCV-coinfected patients receiving IFN-based therapy at baseline (HIV/HCV-b) and week 24 after sustained virological response (HIV/HCV-f). [...]
2021 - 10.1186/s12929-021-00718-6
Journal of Biomedical Science, Vol. 28 Núm. 1 (december 2021) , p. 23
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18 p, 1.3 MB |
Machine learning in critical care : state-of-the-art and a sepsis case study
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Vellido, Alfredo (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Ribas, Vicent (Eurecat, Centre Tecnològic de Catalunya) ;
Morales, Carles (Universitat Politècnica de Catalunya. Centre de Recerca en Ciència de Dades Intel·ligents i Intel·ligència Artificial) ;
Ruiz Sanmartín, Adolfo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz Rodríguez, Juan Carlos (Universitat Autònoma de Barcelona. Departament de Medicina)
Like other scientific fields, such as cosmology, high-energy physics, or even the life sciences, medicine and healthcare face the challenge of an extremely quick transformation into data-driven sciences. [...]
2018 - 10.1186/s12938-018-0569-2
BioMedical Engineering OnLine, Vol. 17 (november 2018)
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41 p, 3.4 MB |
Polarization gating based on Mueller matrices
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Lizana Tutusaus, Ángel (Universitat Autònoma de Barcelona. Departament de Física) ;
Van Eeckhout, Albert (Universitat Autònoma de Barcelona. Departament de Física) ;
Adamczyk, Kamil (Universitat Autònoma de Barcelona. Departament de Física) ;
Rodríguez, Carla (Universitat Autònoma de Barcelona. Departament de Física) ;
Escalera Merino, Juan Carlos (Universitat Autònoma de Barcelona. Departament de Física) ;
Garcia-Caurel, Enric (Université Paris Saclay. Laboratoire de Physique des Interfaces et des Couches Minces) ;
Moreno, Ignacio (Universidad Miguel Hernández de Elche. Departamento de Ciencia de Materiales, Óptica y Tecnología Electrónica) ;
Campos Coloma, Juan (Universitat Autònoma de Barcelona. Departament de Física)
We present mathematical formulas generalizing polarization gating (PG) techniques. PG refers to a collection of imaging methods based on the combination of different controlled polarization channels. [...]
2017 - 10.1117/1.JBO.22.5.056004
Journal of biomedical optics, Vol. 22, issue 5 (May 2017) , p. 56004-1-56004-14
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30 p, 1.4 MB |
Cytocompatibility assessment of Ti-Zr-Pd-Si-(Nb) alloys with low Young's modulus, increased hardness and enhanced osteoblast differentiation for biomedical applications
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Blanquer Jerez, Andreu (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Musilkova, J. (Fyziologický ústav AV ČR) ;
Barrios, Leonardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ibáñez, Elena (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Vandrovcova, M. (Fyziologický ústav AV ČR) ;
Pellicer Vilà, Eva Maria (Universitat Autònoma de Barcelona. Departament de Física) ;
Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física) ;
Bacakova, L. (Fyziologický ústav AV ČR) ;
Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Ti-based alloys have increased importance for biomedical applications due to their excellent properties. In particular, the two recently developed TiZrPdSi(Nb) alloys, with a predominant β-Ti phase microstructure, have good mechanical properties, such as a relatively low Young's modulus and high hardness. [...]
2018 - 10.1002/jbm.b.33892
Journal of biomedical materials research: Part B - applied biomaterials, Vol. 106, issue 2 (Feb. 2018) , p. 834-842
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42 p, 4.5 MB |
Designing new biocompatible glass-forming Ti₇₅ˍₓ Zr₁₀ Nbₓ Si₁₅ (x = 0, 15) alloys : corrosion, passivity, and apatite formation
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Abdi, Somayeh (Institut für Festkörper- und Werkstofforschung Dresden) ;
Oswald, Steffen (Institut für Festkörper- und Werkstofforschung Dresden) ;
Gostin, Petre Flaviu (Institut für Festkörper- und Werkstofforschung Dresden) ;
Helth, Arne (Institut für Festkörper- und Werkstofforschung Dresden) ;
Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física) ;
Baró, M. D.. (Universitat Autònoma de Barcelona. Departament de Física) ;
Calin, Mariana (Institut für Festkörper- und Werkstofforschung Dresden) ;
Schultz, Ludwig (Institut für Festkörper- und Werkstofforschung Dresden) ;
Eckert, Jürgen (Institut für Festkörper- und Werkstofforschung Dresden) ;
Gebert, Annett (Institut für Festkörper- und Werkstofforschung Dresden)
Glass-forming Ti-based alloys are considered as potential new materials for implant applications. Ti75-xZr10NbxSi15 alloys (free cytotoxic elements) can be produced as melt-spun ribbons with glassy matrix and embedded single β-type macrocrystals. [...]
2016 - 10.1002/jbm.b.33332
Journal of biomedical materials research: Part B - applied biomaterials, Vol. 104 Issue 1 (Jan. 2016) , p. 27-38
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20 p, 3.0 MB |
Protective coatings for intraocular wirelessly controlled microrobots for implantation : corrosion, cell culture, and in vivo animal tests
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Pokki, Juho (ETH Zürich. Institute of Robotics and Intelligent Systems) ;
Ergeneman, Olgaç (ETH Zürich. Institute of Robotics and Intelligent Systems) ;
Chatzipirpiridis, George (ETH Zürich. Institute of Robotics and Intelligent Systems) ;
Lühmann, Tessa (University of Würzburg. Institute for Pharmacy and Food Chemistry) ;
Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física) ;
Pellicer Vilà, Eva Maria (Universitat Autònoma de Barcelona. Departament de Física) ;
Pot, Simon A. (University of Zurich. Vetsuisse Faculty) ;
Spiess, Bernhard M. (University of Zurich. Vetsuisse Faculty) ;
Pané i Vidal, Salvador (ETH Zürich. Institute of Robotics and Intelligent Systems) ;
Nelson, Bradley J. (ETH Zürich. Institute of Robotics and Intelligent Systems)
Diseases in the ocular posterior segment are a leading cause of blindness. The surgical skills required to treat them are at the limits of human manipulation ability, and involve the risk of permanent retinal damage. [...]
2016 - 10.1002/jbm.b.33618
Journal of Biomedical Materials Research Part B, Vol 104, Issue 1 (January 2016)
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