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178 p, 3.0 MB Circulating ACE2 and kidney disease: modulation of expression and value as a biomarker of atheromatosis progression / Anguiano Gómez, Lidia ; Pascual, Julio, (Pascual Santos), dir. ; Soler, María José, (Soler Romeo), dir. ; Riera Oliva, Marta, dir. ; Bosch, Assumpció, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
L'enzim convertidor d'angiotensina (ECA) 2 és una carboxipeptidasa que degrada l'angiotensina (Ang) II en Ang 1-7, contrarestant els efectes vasoconstrictors i deleteris de l'Ang II. L'activitat circulant de l'ECA2 està augmentada en pacients amb malaltia cardiovascular (CV) i en models experimentals de nefropatia diabètica (ND). [...]
Angiotensin-converting enzyme (ACE) 2 is a carboxypeptidase that degrades angiotensin (Ang) II to Ang 1-7, thus counteracting the vasoconstrictor and deleterious effects of Ang II. Circulating ACE2 activity is increased in patients with cardiovascular (CV) disease and in experimental models of diabetic nephropathy (DN). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

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