UAB Digital Repository of Documents 2 records found  Search took 0.01 seconds. 
1.
10 p, 1.1 MB Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI : Randomized, Placebo-Controlled Phase II Clinical Trial in Patients with Latent Tuberculosis Infection / Nell, Andre S. (PAREXEL Early Phase Clinical Unit, Bloemfontein, South Africa) ; D'lom, Eva (PAREXEL International, Madrid, Spain) ; Bouic, Patrick (Synexa Life Sciences, Cape Town, South Africa) ; Sabaté, Montserrat (TFS Develop, Barcelona, Catalonia, Spain) ; Bosser, Ramon (Janus Developments (Barcelona, Catalunya)) ; Picas, Jordi (Archivel Farma) ; Amat, Mercè (Archivel Farma) ; Churchyard, Gavin (The Aurum Institute, Johannesburg, South Africa) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
To evaluate the safety, tolerability and immunogenicity of three different doses (5, 25 and 50 µg) of the novel antituberculous vaccine RUTI compared to placebo in subjects with latent tuberculosis infection. [...]
2014 - 10.1371/journal.pone.0089612
PloS one, Vol. 9 (february 2014)  
2.
7 p, 774.5 KB Expanding the recombinant protein quality in Lactococcus lactis / Cano-Garrido, Olivia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rueda, Fabián L. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Sánchez-García, Laura (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ruiz-Ávila, Luis (Spherium Biomed S.L.) ; Bosser, Ramon (Spherium Biomed S.L.) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: Escherichia coli has been a main host for the production of recombinant proteins of biomedical interest, but conformational stress responses impose severe bottlenecks that impair the production of soluble, proteolytically stable versions of many protein species. [...]
2014 - 10.1186/s12934-014-0167-3
Microbial cell factories, Vol. 13 (2014) , p. 167  

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