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12 p, 1.2 MB Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21 / Carreras Sureda, Amado, 1986- (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Rubio Moscardo, Fanny (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Argilaguet, Jordi 1977- (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Kiefer, Kerstin (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Meyerhans, Andreas (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vicente, Rubén (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut)
Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression levels of ORMDL3, GSDMB and ZPBP2 genes. [...]
2016 - 10.1371/journal.pone.0166414
PloS one, Vol. 11 Núm. 11 (November 2016)  
Detailed record - Creative Commons

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