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22 p, 4.2 MB A flexible count data model to fit the wide diversity of expression profiles arising from extensively replicated RNA-seq experiments / Esnaola, Mikel (Centre de Recerca en Epidemiologia Ambiental (Barcelona)) ; Puig Casado, Pedro (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; González Buisán, David (Centre de Regulació Genòmica (Barcelona)) ; Castelo, Robert (Universitat Pompeu Fabra. Department of Experimental and Health Sciences) ; González Ruiz, Juan Ramón (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
Background: High-throughput RNA sequencing (RNA-seq) offers unprecedented power to capture the real dynamics of gene expression. Experimental designs with extensive biological replication present a unique opportunity to exploit this feature and distinguish expression profiles with higher resolution. [...]
2013 - 10.1186/1471-2105-14-254
BMC bioinformatics, Vol. 14, N. 254 (August 2013) , p. 1-47
2 documents

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