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17 p, 1.6 MB Late Onset of Estrogen Therapy Impairs Carotid Function of Senescent Females in Association with Altered Prostanoid Balance and Upregulation of the Variant ERα36 / Costa, Tiago J. (Universidade de São Paulo. Department of Pharmacology) ; Jiménez Altayó, Francesc (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Echem, Cinthya (Universidade de São Paulo. Department of Pharmacology) ; Akamine, Eliana Hiromi (Universidade de São Paulo. Department of Pharmacology) ; Tostes, Rita (Universidade de São Paulo. Department of Pharmacology) ; Vila Calsina, Elisabet (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dantas, A. P. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Catelli de Carvalho, Maria Helena (Universidade de São Paulo. Department of Pharmacology)
Recent analysis of clinical trials on estrogen therapy proposes the existence of a therapeutic window of opportunity for the cardiovascular benefits of estrogens, which depend on women's age and the onset of therapy initiation. [...]
2019 - 10.3390/cells8101217
Cells, Vol. 8 Núm. 10 (2019) , p. 1-17  
Detailed record - Creative Commons

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