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32 p, 9.6 MB |
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
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Duperron, Marie-Gabrielle (Bordeaux University Hospital(França)) ;
Knol, Maria J. (Erasmus MC University Medical Center) ;
Le Grand, Quentin (Bordeaux Population Health Research Center) ;
Evans, Tavia E. (Erasmus MC University Medical Center) ;
Mishra, Aniket (University of Bordeaux) ;
Tsuchida, Ami (University of Bordeaux) ;
Roshchupkin, Gennady V (Erasmus MC University Medical Center) ;
Konuma, Takahiro (Osaka University Graduate School of Medicine) ;
Trégouët, David-Alexandre (University of Bordeaux) ;
Romero, Jose Rafael (The Framingham Heart Study) ;
Frenzel, Stefan (University Medicine Greifswald) ;
Luciano, Michelle (University of Edinburgh) ;
Hofer, Edith (Medical University of Graz) ;
Bourgey, Mathieu (McGill University) ;
Dueker, Nicole D. (University of Miami) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hilal, Saima (National University of Singapore and National University Health System) ;
Tankard, Rick M. (Curtin University) ;
Dubost, Florian (Erasmus MC University Medical Center) ;
Shin, Jean (University of Toronto) ;
Saba, Yasaman (Medical University of Graz) ;
Armstrong, Nicola (Curtin University) ;
Bordes, Constance (Bordeaux Population Health Research Center) ;
Bastin, Mark E. (University of Edinburgh) ;
Beiser, Alexa (Boston University School of Public Health) ;
Brodaty, Henry (Dementia Collaborative Research Centre Assessment and Better Care) ;
Bülow, Robin (University Medicine Greifswald) ;
Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ;
Chen, Christopher (National University of Singapore) ;
Cheng, Ching-Yu (Duke-NUS Medical School) ;
Deary, Ian J. (University of Edinburgh) ;
Gampawar, Piyush G. (Medical University of Graz) ;
Himali, Jayandra J. (UT Health San Antonio) ;
Jiang, Jiyang (University of New South Wales) ;
Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ;
Li, Shuo (Boston University School of Public Health) ;
Macalli, Melissa (University of Bordeaux) ;
Marquis, Pascale (McGill University) ;
Morris, Zoe (Royal Infirmary of Edinburgh) ;
Muñoz Maniega, Susana (UK Dementia Research Institute Centre at the University of Edinburgh) ;
Miyamoto, Susumu (Kyoto University Hospital) ;
Okawa, Masakazu (Kyoto University Graduate School of Medicine) ;
Paradise, Matthew (University of New South Wales) ;
Parva, Pedram (Harvard Medical School) ;
Rundek, Tatjana (University of Miami) ;
Sargurupremraj, Muralidharan (University of Bordeaux) ;
Schilling, Sabrina (University of Bordeaux) ;
Setoh, Kazuya (Shizuoka Graduate University of Public Health) ;
Soukarieh, Omar (University of Bordeaux) ;
Tabara, Yasuharu (Shizuoka Graduate University of Public Health) ;
Teumer, Alexander (University Medicine Greifswald) ;
Thalamuthu, Anbupalam (University of New South Wales) ;
Trollor, Julian (UNSW) ;
Valdés Hernández, Maria C. (University of Edinburgh) ;
Vernooij, Meike W. (Erasmus MC University Medical Center) ;
Völker, Uwe (University Medicine Greifswald) ;
Wittfeld, Katharina (German Center for Neurodegenerative Diseases) ;
Wong, Tien Yin (Tsinghua University) ;
Wright, Margaret J. (University of Queensland) ;
Zhang, Junyi (Peking Union Medical College Hospital) ;
Zhao, Wanting (Duke-NUS Medical School) ;
Zhu, Yi-Cheng (Peking Union Medical College Hospital) ;
Schmidt, Helena (Medical University of Graz) ;
Sachdev, Perminder S. (the Prince of Wales Hospital) ;
Wen, Wei (University of New South Wales) ;
Yoshida, Kazumichi (Kyoto University Graduate School of Medicine) ;
Joutel, Anne (Université Paris Cité) ;
Satizabal, Claudia L. (UT Health San Antonio) ;
Sacco, Ralph L. (University of Miami) ;
Bourque, Guillaume (McGill University) ;
Lathrop, Mark (Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University) ;
Paus, Tomas (University of Toronto) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Yang, Qiong (Boston University School of Public Health) ;
Mazoyer, Bernard (Bordeaux University Hospital (França)) ;
Boutinaud, Philippe (Fealinx) ;
Okada, Yukinori (University of Tokyo) ;
Grabe, Hans J. (German Center for Neurodegenerative Diseases) ;
Mather, Karen A (Neuroscience Research Australia) ;
Schmidt, Reinhold (Medical University of Graz) ;
Joliot, Marc (University of Bordeaux) ;
Ikram, M. Arfan (Erasmus MC University Medical Center) ;
Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ;
Tzourio, Christophe (Bordeaux University Hospital(França)) ;
Wardlaw, Joanna (University of Edinburgh) ;
Seshadri, Sudha (UT Health San Antonio) ;
Adams, Hieab (Universidad Adolfo Ibáñez) ;
Debette, Stéphanie (Bordeaux University Hospital(França)) ;
Universitat Autònoma de Barcelona
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up to 40,095 participants (18 population-based cohorts, 66. [...]
2023 -  10.1038/s41591-023-02268-w
Nature Medicine, Vol. 29 (april 2023) , p. 950-962
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10 p, 736.9 KB |
Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage : a systematic review and meta-analysis of individual patient data
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Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences. University of Edinburgh) ;
Frantzias, Joseph (King's College Hospital NHS Foundation Trust) ;
Lee, Robert J. (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK) ;
Lyden, Patrick D. (Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA) ;
Battey, Thomas W. K. (Massachusetts General Hospital (Boston)) ;
Ayres, Alison M. (Massachusetts General Hospital (Boston)) ;
Goldstein, Joshua N. (Massachusetts General Hospital (Boston)) ;
Mayer, Stephan A. (Department of Neurology, Henry Ford Health System, Detroit, MI, USA) ;
Steiner, Thorsten (Heidelberg University Hospital (Alemanya)) ;
Wang, Xia (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ;
Arima, Hisatomi (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ;
Hasegawa, Hitoshi (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Oishi, Makoto (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Godoy, Daniel A. (Intensive Care Unit, Hospital Interzonal de Agudos "San Juan Bautista", Catamarca, Argentina) ;
Masotti, Luca (Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy) ;
Dowlatshahi, Dar (Department of Medicine (Neurology), University of Ottawa and Ottawa Hospital Research Institute, Ottawa, ON, Canada) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jang, Dong-Kyu (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castillo, José (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Yao, Xiaoying (Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China) ;
Claassen, Jan (Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ;
Volbers, Bastian (Bern University Hospital) ;
Kazui, Seiji (Kazui Medical Office, Ikeda, Osaka, Japan) ;
Okada, Yasushi (Department of Cerebrovascular Medicine and Neurology, National Hospital Organisation Kyushu Medical Centre, Fukuoka, Japan) ;
Fujimoto, Shigeru (Division of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan) ;
Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ;
Li, Qi (Department of Neurology, ThE First Affiliated Hospital of Chongqing Medical University, Chongqing, China) ;
Khoury, Jane (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Cai, Chunyan (Centre for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA) ;
Kate, Mahesh P. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
McCourt, Rebecca (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
Venkatasubramanian, Chitra (Division of Stroke and Neurocritical Care, Stanford University, Palo Alto, CA, USA) ;
Diringer, Michael N. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ;
Ikeda, Yukio (Department of Neurosurgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan) ;
Worthmann, Hans (Department of Neurology, Hannover Medical School, Hannover, Germany) ;
Ziai, Wendy C. (Johns Hopkins University School of Medicine, Department of Neurology, Anaesthesia and Critical Care Medicine, Division of Neurocritical Care, Baltimore, MD, USA) ;
d'Esterre, Christopher D. (Department of Radiology, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada) ;
Aviv, Richard I (Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada) ;
Raab, Peter (Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany) ;
Murai, Yasuo (Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan) ;
Zazulia, Allyson R. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ;
Butcher, Kenneth S. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
Seyedsaadat, Seyed Mohammad (Department of Radiology, Mayo Clinic, Rochester, MN, USA) ;
Grotta, James C. (Memorial Hermann Hospital (Houston, Estats Units d'Amèrica)) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Broderick, Joseph P (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ;
Yamamoto, Haruko (Center for Advanced Clinical and Translational Sciences, National Cerebral and Cerebrovascular Center, Suita, Osaka, Japan) ;
Staykov, Dimitre (Department of Neurology, Hospital of the Brothers of St John, Eisenstadt, Austria) ;
Connolly, E. Sander (Department of Neurosurgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ;
Selim, Magdy (Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ;
Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Moon, Byung Hoo (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ;
Demchuk, Andrew (Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada) ;
Di Napoli, Mario (Neurological Service, San Camillo de'Lellis General Hospital, Rieti, Italy) ;
Fujii, Yukihiko (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Anderson, Craig S.. (The George Institute for Global Health, China at Peking University Health Science Center, Beijing, China) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Universitat Autònoma de Barcelona
Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography. [...]
2018 - 10.1016/S1474-4422(18)30253-9
The Lancet neurology, Vol. 17 (october 2018) , p. 885-894
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