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12 p, 840.2 KB |
Hypoxic burden to guide CPAP treatment allocation in patients with obstructive sleep apnoea : a post hoc study of the ISAACC trial
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Pinilla, Lucía (University Hospital Arnau de Vilanova and Santa María) ;
Esmaeili, Neda (Isfahan University of Medical Sciences, Isfahan, Iran.) ;
Labarca, Gonzalo (Brigham and Women's Hospital and Harvard Medical School, Boston, USA) ;
Martinez-Garcia, Miguel Ángel (Hospital Universitario y Politécnico La Fe, Valencia) ;
Torres, Gerard (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Gracia-Lavedan, Esther (Institut de Recerca Biomèdica de Lleida) ;
Mínguez, Olga (Institut de Recerca Biomèdica de Lleida) ;
Martínez López, Dolores (Institut de Recerca Biomèdica de Lleida) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Masdeu, Maria José (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Mediano, Olga (Pneumology Department, University Hospital of Guadalajara) ;
Muñoz, Carmen (Hospital Universitario de Burgos) ;
Cabriada, Valentín (University Hospital of Cruces, Bizkaia) ;
Duran-Cantolla, Joaquín (University Hospital of Araba, Vitoria) ;
Mayos, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Coloma, Ramón (Complejo Hospitalario Universitario de Albacete) ;
Montserrat, Josep María (Hospital Clínic i Provincial de Barcelona) ;
de la Peña, Mónica (University Hospital Son Espases, Palma de Mallorca) ;
Hu, Wen-Hsin (Brigham and Women's Hospital and Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Messineo, Ludovico (Brigham and Women's Hospital and Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Sehhati, Mohammadreza (Isfahan University of Medical Sciences, Isfahan, Iran) ;
Wellman, Andrew (Brigham and Women's Hospital and Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Redline, Susan (Brigham and Women's Hospital and Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Sands, Scott (Brigham and Women's Hospital and Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Barbé, Ferran (Institut de Recerca Biomèdica de Lleida) ;
Sánchez-de-la-Torre, Manuel (University Hospital Arnau de Vilanova and Santa María) ;
Azarbarzin, Ali (Brigham and Women's Hospital and Harvard Medical School, Boston, USA) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Hypoxic burden (HB) has emerged as a strong predictor of cardiovascular risk in obstructive sleep apnoea (OSA). We aimed to assess the potential of HB to predict the cardiovascular benefit of treating OSA with continuous positive airway pressure (CPAP). [...]
2023 -  10.1183/13993003.00828-2023
European respiratory journal, Vol. 62, Num. 6 (december 2023)
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16 p, 1.1 MB |
Characterization and Factors Associated with Poor Asthma Control in Adults with Severe Eosinophilic Asthma
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Padró-Casas, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Basagaña, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rivera-Ortún, María Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-Olivé, Ignasi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pollan-Guisasola, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teniente-Serra, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Cáceres, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Navarro, José Tomás (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rosell, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roger, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
A study was conducted in 98 adult patients diagnosed with severe eosinophilic asthma (73. 5% women, mean age 47. 2 years) and followed prospectively for 1 year. The aim of the study was to characterize this population and to identify factors associated with poor prognosis at 1 year of follow-up. [...]
2023 - 10.3390/jpm13071173
Journal of personalized medicine, Vol. 13 Núm. 7 (july 2023)
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7 p, 1.1 MB |
Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency
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Marin-Bejar, Oskar (Institut d'Investigació Biomèdica de Bellvitge) ;
Romero-Moya, Damia (Institut d'Investigació Biomèdica de Bellvitge) ;
Rodriguez-Ubreva, Javier (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Distefano, Maximiliano (Hospital Sant Joan de Déu (Manresa)) ;
Lessi, Francesca (Fondazione Pisana Per la Scienza ONLUS (FPS)) ;
Aretini, Paolo (Fondazione Pisana Per la Scienza ONLUS (FPS)) ;
Liquori, Alessandro (Instituto de Salud Carlos III) ;
Castaño, Julio (Banc de Sang i Teixits) ;
Kozyra, Emilia (University of Freiburg) ;
Kotmayer, Lili (Semmelweis University. Budapest, Hungary) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Cervera, José (Hospital Universitari i Politècnic La Fe (València)) ;
Rodriguez-Gallego, José Carlos (University of Las Palmas de Gran Canaria) ;
Nomdedeu, Josep Francisco (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Murillo- Sanjuán, Laura (Vall d'Hebron Institut d'Oncologia) ;
de Heredia, Cristina Díaz (Vall d'Hebron Institut d'Oncologia) ;
Pérez-Martinez, Antonio (Universidad Autónoma de Madrid) ;
López-Cadenas, Félix (Instituto Biosanitario de Salamanca (IBSAL)) ;
Martínez-Laperche, Carolina (Hospital Gregorio Marañón. Instituto de Investigación Sanitaria) ;
Dorado-Herrero, Nieves (Hospital Gregorio Marañón. Instituto de Investigación Sanitaria) ;
Marco, Francisco M. (Institute for Health and Biomedical Research (ISABIAL)) ;
Prósper, Felipe (Instituto de Salud Carlos III) ;
Menendez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Valcárcel, David (Vall d'Hebron Institut d'Oncologia) ;
Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bödör, Csaba (Semmelweis University. Budapest, Hungary) ;
Bigas Salvans, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Catalá, Albert (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Wlodarski, Marcin W. (St. Jude Children's Research Hospital, Memphis, TN) ;
Giorgetti, Alessandra (Institut d'Investigació Biomèdica de Bellvitge) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
2023 - 10.3324/haematol.2022.282305
Haematologica, Vol. 108 Núm. 9 (september 2023) , p. 2551-2557
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16 p, 4.7 MB |
BCL3 rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases
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Carbo-Meix, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Guijarro, Francesca (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Wang, Luojun (Hospital Clínic i Provincial de Barcelona) ;
Grau, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Royo, Romina (Barcelona Supercomputing Center) ;
Frigola, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Playa-Albinyana, Heribert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Buhler, Marco M. (University Hospital Zurich (Suïssa)) ;
Clot, Guillem (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Duran-Ferrer, Marti (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lu, Junyan (European Molecular Biology Laboratory, Heidelberg) ;
Granada, Isabel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Navarro, Jose Tomas (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bandiera, Laura (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
De Canal, Gabriella (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
Bonoldi, Emanuela (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
Climent, Fina (Institut d'Investigació Biomèdica de Bellvitge) ;
Ribera-Cortada, Inmaculada (Hospital Nostra Senyora de Meritxell. Escaldes-Engordany. Principat d'Andorra) ;
Fernandez-Caballero, Mariana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
De la Banda, Esmeralda (Institut d'Investigació Biomèdica de Bellvitge) ;
Do Nascimento, Janilson (Hospital Joan XXIII, Institut Català d'Oncologia, Tarragona) ;
Pineda, Alberto (Fundació Hospital de l'Esperit Sant) ;
Vela, Dolors (Hematologia Clínica. Hospital General de Granollers) ;
Rozman, Maria (Hospital Clínic i Provincial de Barcelona) ;
Aymerich, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Syrykh, Charlotte (Cancer Institute University of Toulouse-Oncopole, France) ;
Brousset, Pierre (Cancer Institute University of Toulouse-Oncopole, France) ;
Perera, Miguel (Hospital Dr Negrín, Las Palmas de Gran Canaria) ;
Yanez, Lucrecia (Hematology Department. Hospital Universitario Marqués de Valdecilla-Instituto de Investigación Valdecilla) ;
Ortin, Jesus Xavier (Hematology Department. Hospital Verge de la Cinta) ;
Tuset, Esperanza (Institut d'Investigació Biomèdica de Girona) ;
Zenz, Thorsten (University Hospital and University of Zürich) ;
Cook, James R. (Pathology and Laboratory Medicine Institute. Cleveland Clinic) ;
Swerdlow, Steven H. (University of Pittsburgh School of Medicine) ;
Martin-Subero, Jose I. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Colomer, Dolors (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Bea, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Costa, Dolors (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Nadeu, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Campo, Elias (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The t(14;19)(q32;q13) often juxtaposes BCL3 with immunoglobulin heavy chain (IGH) resulting in overexpression of the gene. In contrast to other oncogenic translocations, BCL3 rearrangement (BCL3-R) has been associated with a broad spectrum of lymphoid neoplasms. [...]
2024 - 10.3324/haematol.2023.283209
Haematologica, Vol. 109 Núm. 2 (february 2024) , p. 493-508
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11 p, 767.6 KB |
Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS
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Trebicka, Jonel (Institut de Bioenginyeria de Catalunya) ;
Gu, Wenyi (Shanghai Jiao Tong University) ;
Ibáñez-Samaniego, Luis (Hospital General Universitario Gregorio Marañón) ;
Hernández-Gea, Virginia (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Pitarch, Carla (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García López, Elisabet (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Procopet, Bogdan ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Giráldez-Gallego, Álvaro (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Amitrano, Lucio (Ospedale A Cardarelli) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Thabut, Dominique (Paris Sorbonne Université) ;
Silva-Junior, Gilberto (Hospital Clínic i Provincial de Barcelona) ;
Martinez, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bureau, Cristophe (University Paul Sabatier of Toulouse) ;
Llop, Elba (Universidad Autónoma de Madrid) ;
Laleman, Wim (University Hospitals Leuven (Bèlgica)) ;
Palazon, Jose Maria (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Castellote, Jose (Hospital Universitari de Bellvitge) ;
Rodrigues, Susana G. (Centro Hospitalar São João) ;
Gluud, Lise Lotte (University of Copenhagen) ;
Ferreira, Carlos Noronha (Hospital de Santa Maria - Centro Hospitalar Lisboa Norte) ;
Barcelo, Rafael (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cañete Hidalgo, Nuria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez, Manuel (Hospital Universitario Central de Asturias) ;
Ferlitsch, Arnulf (Medical University of Vienna) ;
Mundi Sánchez-Ramade, Jose Luis (Hospital Universitario San Cecilio (Granada)) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Hernandez-Guerra, Manuel (Hospital Universitario de Canarias (La Laguna)) ;
Sassatelli, Romano (Arcispedale Santa Maria Nuova-IRCCS) ;
Dell'Era, Alessandra (University of the Studies of Milan) ;
Senzolo, Marco (University Hospital of Padova (Pàdua, Itàlia)) ;
Abraldes, Juan G. (University of Alberta) ;
Romero-Gómez, Manuel (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Zipprich, Alexander (Martin Luther University Halle-Wittenberg) ;
Casas, Meritxell (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Primignani, Massimo (CRC "A.M.and A.Miglaivacca" Center for Liver Disease) ;
Weiss, Emmanuel (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Catalina, María-Vega (Hospital General Universitario Gregorio Marañón) ;
Erasmus, Hans Peter (University of Frankfurt) ;
Uschner, Frank Erhard (University of Frankfurt) ;
Schulz, Martin (University of Frankfurt) ;
Brol, Maximilian Joseph (University of Bonn) ;
Praktiknjo, Michael (University of Bonn) ;
Chang, Johannes (University of Bonn) ;
Krag, Aleksander (Odense University Hospital (Dinamarca)) ;
Nevens, Frederik (University Hospitals Leuven (Bèlgica)) ;
Calleja, Jose Luis (Universidad Autónoma de Madrid) ;
Robic, Marie Angèle (University Paul Sabatier of Toulouse) ;
Conejo, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Rudler, Marika (Paris Sorbonne Université) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Guardascione, Maria Anna (Ospedale A Cardarelli) ;
Tantau, Marcel ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Bosch, Jaime (Bern University) ;
Torres, Ferran (Hospital Clínic i Provincial de Barcelona) ;
Pavesi, Marco (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García-Pagán, JC (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Jansen, Christian (University of Bonn) ;
Bañares, Rafael (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, the prevalence and prognosis of ACLF in the context of AVB is unclear, while the role of transjugular intrahepatic portosystemic shunt (TIPS) in the management in patients with ACLF has not been described to date. [...]
2020 - 10.1016/j.jhep.2020.04.024
Journal of Hepatology, Vol. 73 Núm. 5 (november 2020) , p. 1082-1091
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12 p, 1.2 MB |
Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes : A Systematic Review and Meta-Analysis
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Xie, Suyi (The Chinese University of Hong Kong) ;
Li, Qi (The Chinese University of Hong Kong) ;
Luk, Andrea O. Y. (The Chinese University of Hong Kong) ;
Lan, Hui-Yao (The Chinese University of Hong Kong) ;
Chan, Paul K. S. (The Chinese University of Hong Kong) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Chan, Francis K. L. (The Chinese University of Hong Kong) ;
Fung, Erik (The Chinese University of Hong Kong) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: Growth differentiation factor 15 (GDF-15) is a homeostatic cytokine that regulates neural and cardio-metabolic functions, and its release is increased in response to stress, injury, and inflammation. [...]
2022 - 10.3390/biom12070934
Biomolecules, Vol. 12, Num. 7 (july 2022)
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13 p, 446.0 KB |
Do Sex/Gender and Menopause Influence the Psychopathology and Comorbidity Observed in Delusional Disorders?
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González-Rodríguez, Alexandre (Universitat de Barcelona) ;
Seeman, Mary (University of Toronto, Canada) ;
Díaz-Pons, Alexandre (University of Cantabria) ;
Ayesa-Arriola, Rosa (University of Cantabria) ;
Natividad, Mentxu (Universitat de Barcelona) ;
Calvo-Sánchez, Eva (Universitat de Barcelona) ;
Monreal, José Antonio (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background : While sex differences and gonadal hormone levels are taken seriously in the understanding and treatment of schizophrenia, their influence in the psychopathology of delusional disorders (DD) remains unknown. [...]
2022 - 10.3390/jcm11154550
Journal of clinical medicine, Vol. 11 (august 2022)
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12 p, 2.6 MB |
Traffic Lights Intervention Reduces Therapeutic Inertia : A Randomized Controlled Trial in Multiple Sclerosis Care
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Saposnik, Gustavo (St. Michael's Hospital, Toronto) ;
Mamdani, Muhammad (Li Ka Shing Centre for Healthcare Analytics Research and Training (LKS-CHART)) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron) ;
Terzaghi, Maria (St. Michael's Hospital, Toronto) ;
Silva, Berenice (Institute of Neuroscience Buenos Aires (INEBA)) ;
Saladino, Maria Laura (Institute of Neuroscience Buenos Aires (INEBA)) ;
Tobler, Philippe N. (University of Zurich) ;
Caceres, Fernando (Institute of Neuroscience Buenos Aires (INEBA)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: Therapeutic inertia (TI) is a common phenomenon among physicians who care for patients with chronic conditions. We evaluated the efficacy of the traffic light system (TLS) educational intervention to reduce TI among neurologists with MS expertise. [...]
2019 - 10.1177/2381468319855642
MDM Policy and Practice, Vol. 4 Núm. 1 (2019) , p. 1-12
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