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11 p, 1.8 MB Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis / Annibali, Daniela (University of California) ; Whitfield, Jonathan R. (Vall d'Hebron Institut d'Oncologia) ; Favuzzi, Emilia (Università La Sapienza) ; Jauset, Toni (Universitat Autònoma de Barcelona) ; Serrano, Erika (Universitat Autònoma de Barcelona) ; Cuartas, Isabel (Universitat Autònoma de Barcelona) ; Redondo Campos, Sara (Universitat Autònoma de Barcelona) ; Folch, Gerard (Universitat Autònoma de Barcelona) ; Gonzàlez Juncà, Alba (Universitat Autònoma de Barcelona) ; Sodir, Nicole M. (University of Cambridge) ; Massó Vallés, Daniel (Universitat Autònoma de Barcelona) ; Beaulieu, Marie-Eve (Universitat Autònoma de Barcelona) ; Swigart, Lamorna B. (University of California) ; Mc Gee, Margaret M. (University College Dublin) ; Somma, Maria Patrizia (Università La Sapienza) ; Nasi, Sergio (Università La Sapienza) ; Seoane Suárez, Joan (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Evan, Gerard I. (University of Cambridge) ; Soucek, Laura (Universitat Autònoma de Barcelona)
Gliomas are the most common primary tumours affecting the adult central nervous system and respond poorly to standard therapy. Myc is causally implicated in most human tumours and the majority of glioblastomas have elevated Myc levels. [...]
2014 - 10.1038/ncomms5632
Nature Communications, Vol. 5 (August 2014) , art. 4632  

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