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264 p, 5.4 MB |
Graphene microtransistors : a wide-bandwidth technology for recording brain field potentials
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Masvidal Codina, Eduard ;
Guimerà Brunet, Anton, dir. ;
Garrido, Jose, dir. ;
Serra Graells, Francesc, dir.
En aquesta tesi doctoral es desenvolupen interfícies neuronals basades en transistors de grafè d'efecte de camp modulats per electròlit (gSGFETs), s'avalua la seva viabilitat per al registre in vivo de potencials de camp cerebral i es compara amb tecnologies de registre d'última generació. [...]
En esta tesis doctoral, se desarrollan interfaces neuronales basadas en transistores de efecto de campo modulados por solución de grafeno (gSGFET) y se evalúa su viabilidad para el registro del potencial de campo cerebral in vivo. [...]
High density recordings of neural activity within and across brain regions are vital in research focused to uncover the underlying processes of complex brain functions and pathophysiology; have applications in medical diagnosis, prognosis and treatment monitoring and are the base of assistive neuroprosthesis. [...]
2021
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278 p, 21.8 MB |
High-Bandwidth Graphene Neural Interfaces
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Garcia Cortadella, Ramon ;
Garrido, Jose, dir. ;
Guimerà Brunet, Anton, dir. ;
Jiménez Jiménez, David, dir.
El funcionament del cervell es basa en processos complexos, que encara no s'han descrit i comprès detalladament. En les últimes dècades, la neurociència ha experimentat un desenvolupament accelerat, impulsat per noves neurotecnologías que permeten monitoritzar les dinàmiques de l'activitat elèctrica al cervell amb una major resolució espai-temporal i una àrea de cobertura més àmplia. [...]
El funcionamiento del cerebro se basa en procesos complejos, que aún no se han descrito y comprendido detalladamente. En las últimas décadas, la neurociencia ha experimentado un desarrollo acelerado, impulsado por nuevas neurotecnologías que permiten monitorear la dinámica de la actividad eléctrica en el cerebro con una mayor resolución espacio-temporal y un área de cobertura más amplia. [...]
2021
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1 p, 361.3 KB |
Author correction : Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity
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Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia) ;
Schwesig, G. (Ludwig-Maximilians-Universität München. Bernstein Center for Computational Neuroscience Munich) ;
Jeschke, C. (Multi Channel Systems GmbH) ;
Illa, Xavi (Institut de Microelectrònica de Barcelona) ;
Gray, Anna L. (University of Manchester. National Graphene Institute. Nanomedicine Lab) ;
Savage, S. (University of Manchester. National Graphene Institute. Nanomedicine Lab) ;
Stamatidou, E. (University of Manchester. National Graphene Institute. Nanomedicine Lab) ;
Schiessl, I. (University of Manchester. Division of Neuroscience and Experimental Psychology) ;
Masvidal Codina, Eduard (Institut de Microelectrònica de Barcelona) ;
Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Sirota, Anton (Ludwig-Maximilians-Universität München. Bernstein Center for Computational Neuroscience Munich) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia)
The original version of this article included an incorrectly named funding source "Graphene Flagship", and omitted the names of GrapheneCore 2 and GrapheneCore3 as funding sources, from the Acknowledgements. [...]
2021 -  10.1038/s41467-021-23078-z
Nature communications, Vol. 12 (April 2021) , art. 2568
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20 p, 3.5 MB |
Characterization of optogenetically-induced cortical spreading depression in awake mice using graphene micro-transistor arrays
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Masvidal Codina, Eduard (Institut de Microelectrònica de Barcelona) ;
Smith, Trevor M. (University College London. Queen Square Institute of Neurology. Department of Clinical and Experimental Epilepsy) ;
Rathore, Daman (University College London. Queen Square Institute of Neurology. Department of Clinical and Experimental Epilepsy) ;
Gao, Yunan (University College London. Queen Square Institute of Neurology. Department of Clinical and Experimental Epilepsy) ;
Illa, Xavi (Institut de Microelectrònica de Barcelona) ;
Prats-Alfonso, Elisabet (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Del Corro, Elena (Institut Català de Nanociència i Nanotecnologia) ;
Bonaccini Calia, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Rius, Gemma (Institut de Microelectrònica de Barcelona) ;
Martin-Fernandez, Iñigo (Institut de Microelectrònica de Barcelona) ;
Guger, Christoph (Guger Technologies OG. G.tec Medical Engineering GmbH (Austria)) ;
Reitner, Patrick (Guger Technologies OG. G.tec Medical Engineering GmbH (Austria)) ;
Villa, Rosa (Institut de Microelectrònica de Barcelona) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Wykes, Robert C (University of Manchester. Geoffrey Jefferson Brain Research Centre)
Objective. The development of experimental methodology utilizing graphene micro-transistor arrays to facilitate and advance translational research into cortical spreading depression (CSD) in the awake brain. [...]
2021 - 10.1088/1741-2552/abecf3
Journal of Neural Engineering, Vol. 18, Issue 5 (October 2021) , art. 055002
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129 p, 4.0 MB |
High-density cortical implant for brain-machine interfaces based on two-dimensional materials
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Schaefer, Nathan ;
Garrido, Jose, dir. ;
Guimerà Brunet, Anton, dir. ;
Jiménez Jiménez, David, dir.
El descobriment experimental del grafè el 2004 va suposar l'aparició d'un nou camp de recerca basat en materials bidimensionals, que investiga les seves propietats per a aplicacions en electrònica, fotònica i optoelectrònica i, recentment, també en tecnologia biomèdica. [...]
El descubrimiento experimental del grafeno en 2004 marcó el nacimiento de un nuevo campo de investigación basado en materiales bidimensionales, investigando sus propiedades para aplicaciones en electrónica, fotónica y optoelectrónica y, recientemente, también en tecnología biomédica. [...]
The experimental discovery of graphene in 2004 marked the advent of a new research field based on two-dimensional materials, investigating their properties for applications in electronics, photonics and optoelectronics and, recently, also biomedical technology. [...]
2021
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11 p, 805.0 KB |
Bias dependent variability of low-frequency noise in single-layer graphene FETs
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Mavredakis, Nikolaos (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia) ;
Illa, Xavi (Institut de Microelectrònica de Barcelona) ;
Schaefer, Nathan (Institut Català de Nanociència i Nanotecnologia) ;
Bonaccini Calia, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Jiménez Jiménez, David (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica)
Low-frequency noise (LFN) variability in graphene transistors (GFETs) is for the first time researched in this work under both experimental and theoretical aspects. LFN from an adequate statistical sample of long-channel solution-gated single-layer GFETs is measured in a wide range of operating conditions while a physics-based analytical model is derived that accounts for the bias dependence of LFN variance with remarkable performance. [...]
2020 - 10.1039/d0na00632g
Nanoscale advances, Vol. 2, issue 11 (Nov. 2020) , p. 5450-5460
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17 p, 7.1 MB |
Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity
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Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia) ;
Schwesig, G. (Ludwig-Maximilians-Universität München. Bernstein Center for Computational Neuroscience Munich) ;
Jeschke, C. (Multi Channel Systems GmbH (Germany)) ;
Illa, Xavi (Institut de Microelectrònica de Barcelona) ;
Gray, Anna L. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ;
Savage, S. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ;
Stamatidou, E. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ;
Schiessl, I. (University of Manchester. Division of Neuroscience and Experimental Psychology (UK)) ;
Masvidal Codina, Eduard (Institut de Microelectrònica de Barcelona) ;
Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Sirota, Anton (Ludwig-Maximilians-Universität München. Bernstein Center for Computational Neuroscience Munich) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia)
Graphene active sensors have demonstrated promising capabilities for the detection of electrophysiological signals in the brain. Their functional properties, together with their flexibility as well as their expected stability and biocompatibility have raised them as a promising building block for large-scale sensing neural interfaces. [...]
2021 - 10.1038/s41467-020-20546-w
Nature communications, Vol. 12 (January 2021) , art. 211
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6 p, 1.6 MB |
Effect of channel thickness on noise in organic electrochemical transistors
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Polyravas, Anastasios G. (University of Cambridge. Department of Engineering) ;
Schaefer, Nathan (Institut Català de Nanociència i Nanotecnologia) ;
Curto, Vicenzo Fabio (University of Cambridge. Department of Engineering) ;
Bonaccini Calia, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Malliaras, George (University of Cambridge. Department of Engineering)
Organic electrochemical transistors (OECTs) have been widely used as transducers in electrophysiology and other biosensing applications. Their identifying characteristic is a transconductance that increases with channel thickness, and this provides a facile mechanism to achieve high signal amplification. [...]
2020 - 10.1063/5.0019693
Applied physics letters, Vol. 117, issue 7 (August 2020) , art. 73302
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