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UAB Digital Repository of Documents 2 records found  Search took 0.00 seconds. 
1.
17 p, 2.8 MB Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism / Hasel, Philip (University of Edinburgh) ; Dando, Owen (University of Edinburgh) ; Jiwaji, Zoeb (University of Edinburgh) ; Baxter, Paul (University of Edinburgh) ; Todd, Alison C. (University of Edinburgh) ; Heron, Samuel (University of Edinburgh) ; Márkus, Nóra M. (University of Edinburgh) ; McQueen, Jamie (University of Edinburgh) ; Hampton, David W. (University of Edinburgh) ; Torvell, Megan (University of Edinburgh) ; Tiwari, Sachin S. (University of Edinburgh) ; McKay, Sean (University of Edinburgh) ; Eraso-Pichot, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Zorzano Olarte, Antonio (Universitat de Barcelona) ; Masgrau, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Galea, Elena (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Chandran, Siddharthan (University of Edinburgh) ; Wyllie, David J. A. (University of Edinburgh) ; Simpson, T. Ian (University of Edinburgh) ; Hardingham, Giles E. (University of Edinburgh)
The influence that neurons exert on astrocytic function is poorly understood. To investigate this, we first developed a system combining cortical neurons and astrocytes from closely related species, followed by RNA-seq and in silico species separation. [...]
2017 - 10.1038/ncomms15132
Nature communications, Vol. 8 (may 2017)  
Detailed record - Creative Commons
2.
14 p, 6.3 MB CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons / Pardo Fernández, Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Valor, Luis Miguel (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; Eraso-Pichot, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barco, Ángel (Universidad Miguel Hernández de Elche. Instituto de Neurociencias) ; Golbano Rodríguez, Arantxa (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hardingham, Giles E. (University of Edinburgh. Dementia Research Institute) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Galea, Elena (Universitat Autònoma de Barcelona. Institut de Neurociències)
The cyclic AMP response element binding protein (CREB) is a primary hub of a activity-driven genetic programs in neurons controlling plasticity, neurogenesis and survival. By contrast, the gene networks coordinated by CREB in astrocytes are Unknown despite the fact that the astrocytic CREB is a also activity-driven and neuroprotective. [...]
2017 - 10.1038/s41598-017-06231-x
Scientific reports, Vol. 7(2017) , art. 6390  
Detailed record - Creative Commons

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