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1.
16 p, 760.8 KB Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary ¹³C flux analysis / Jordà Murria, Joel (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Suárez, Camilo (Delft University of Technology. Department of Biotechnology) ; Carnicer Heras, Marc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; ten Pierick, Angela (Delft University of Technology. Department of Biotechnology) ; Heijnen, Joseph J. (Delft University of Technology. Department of Biotechnology) ; van Gulik, Walter (Delft University of Technology. Department of Biotechnology) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Wahl, Aljoscha (Delft University of Technology. Department of Biotechnology)
Background: Several studies have shown that the utilization of mixed carbon feeds instead of methanol as sole carbon source is beneficial for protein production with the methylotrophic yeast Pichia pastoris. [...]
2013 - 10.1186/1752-0509-7-17
BMC systems biology, Vol. 7, Num. 17 (2013) , p. 1-16
7 documents
Detailed record - Creative Commons
2.
10 p, 638.7 KB Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions / Carnicer Heras, Marc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Ten Pierick, Angela (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; van Dam, Jan (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Heijnen, Joseph J. (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; van Gulik, Walter (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Background: Environmental and intrinsic stress factors can result in the global alteration of yeast physiology, as evidenced by several transcriptional studies. Hypoxia has been shown to have a beneficial effect on the expression of recombinant proteins in Pichia pastoris growing on glucose. [...]
2012 - 10.1186/1475-2859-11-83
Microbial cell factories, Vol. 11, N. 83 (June 2012) , p. 1-10
4 documents
Detailed record - Creative Commons

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