Home > Search Results: Kelly, John M.
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UAB Digital Repository of Documents 3 records found  Search took 0.00 seconds. 
1.
8 p, 812.8 KB Tetrasubstituted imidazolium salts as potent antiparasitic agents against African and American trypanosomiases / Ghashghaei, Ouldouz (Universitat de Barcelona. Laboratori de Química Orgànica) ; Kielland, Nicola (Universitat de Barcelona. Laboratori de Química Orgànica) ; Revés, Marc (Universitat de Barcelona. Laboratori de Química Orgànica) ; Taylor, Martin C. (Department of Pathogen Molecular Biology. London School of Hygiene and Tropical Medicine) ; Kelly, John M. (Department of Pathogen Molecular Biology. London School of Hygiene and Tropical Medicine) ; Pietro, Ornella Di (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Pérez, Belén. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lavilla, Rodolfo (Universitat de Barcelona. Laboratori de Química Orgànica)
Imidazolium salts are privileged compounds in organic chemistry, and have valuable biological properties. Recent studies show that symmetric imidazolium salts with bulky moieties can display antiparasitic activity against T. [...]
2018 - 10.3390/molecules23010177
Molecules, Vol. 23 Núm. 1 (2018) , p. 177  
Detailed record - Creative Commons
2.
10 p, 748.9 KB Synthesis and biological evaluation of N -cyanoalkyl-, N -aminoalkyl-, and N -guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents / Sola, Irene (Universitat de Barcelona. Institut de Biomedicina) ; Artigas, Albert (Universitat de Barcelona. Institut de Biomedicina) ; Taylor, Martin C. (London School of Hygiene and Tropical Medicine) ; Pérez-Areales, Francisco Javier (Universitat de Barcelona. Institut de Biomedicina) ; Viayna, Elisabet (Universitat de Barcelona. Institut de Biomedicina) ; Clos, M. Victoria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pérez, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Wright, Colin W. (University of Bradford. Bradford School of Pharmacy) ; Kelly, John M. (London School of Hygiene and Tropical Medicine) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Institut de Biomedicina)
Current drugs against human African trypanosomiasis (HAT) suffer from several serious drawbacks. The search for novel, effective, brain permeable, safe, and inexpensive antitrypanosomal compounds is therefore an urgent need. [...]
2016 - 10.1016/j.bmc.2016.08.036
Bioorganic & Medicinal Chemistry, Vol. 24 (november 2016) , p. 5162-5171  
Detailed record - Creative Commons
3.
18 p, 797.6 KB Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity / Di Pietro, Ornella (Universitat de Barcelona. Institut de Biomedicina) ; Vicente-García, Esther (Barcelona Science Park) ; Taylor, Martin C. (Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine) ; Berenguer, Diana (Universitat de Barcelona. Departament de Microbiologia i Parasitologia Sanitàries) ; Viayna, Elisabet (Universitat de Barcelona. Institut de Biomedicina) ; Lanzoni, Anna (Universitat de Barcelona. Institut de Biomedicina) ; Sola, Irene (Universitat de Barcelona. Institut de Biomedicina) ; Sayago, Helena (Barcelona Science Park) ; Riera, Cristina (Universitat de Barcelona. Departament de Microbiologia i Parasitologia Sanitàries) ; Fisa, Roser (Universitat de Barcelona. Departament de Microbiologia i Parasitologia Sanitàries) ; Clos, M. Victoria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pérez, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Kelly, John M. (Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine) ; Lavilla, Rodolfo (Universitat de Barcelona. Laboratori de Química Orgànica) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Institut de Biomedicina) ; Universitat Autònoma de Barcelona. Institut de Neurociències
Human African trypanosomiasis (HAT), Chagas disease and leishmaniasis, which are caused by the trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania species, are among the most deadly neglected tropical diseases. [...]
2015 - 10.1016/j.ejmech.2015.10.007
European Journal of Medicinal Chemistry, Vol. 105 (november 2015) , p. 120-137  
Detailed record - Creative Commons

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