UAB Digital Repository of Documents 2 records found  Search took 0.00 seconds. 
1.
9 p, 801.8 KB PD-1 Blockade in Anaplastic Thyroid Carcinoma / Capdevila Castillón, Jaume (Vall d'Hebron Institut d'Oncologia) ; Wirth, Lori J. (Harvard Medical School) ; Ernst, Thomas (Universitätsklinikum Jena) ; Ponce Aix, Santiago (Hospital Universitario 12 de Octubre (Madrid)) ; Lin, Chia-Chi (National Taiwan University Hospital (Taipei, Taiwan)) ; Ramlau, Rodryg (Poznań University of Medical Sciences) ; Butler, Marcus O. (Princess Margaret Cancer Centre) ; Delord, Jean-Pierre (IUCT Oncopole) ; Gelderblom, Hans J (Leiden University Medical Center) ; Ascierto, Paolo A. (Istituto Nazionale Tumori IRCCS Fondazione G. Pascale) ; Fasolo, Angelica (San Raffaele Hospital) ; Führer, Dagmar (University Hospital Essen (Alemanya)) ; Hütter-Krönke, Marie Luise (University Hospital of Ulm (Alemanya)) ; Forde, Patrick M. (Sidney Kimmel Comprehensive Cancer Center) ; Wrona, Anna (Uniwersyteckie Centrum Kliniczne) ; Santoro, Armando (IRCCS Humanitas University) ; Sadow, Peter M. (Harvard Medical School) ; Szpakowski, Sebastian (Novartis Institutes for BioMedical Research) ; Wu, Hongqian (Novartis Pharmaceuticals) ; Bostel, Geraldine (Novartis Institutes for BioMedical Research) ; Faris, Jason (Novartis Institutes for BioMedical Research) ; Cameron, Scott (Novartis Institutes for BioMedical Research) ; Varga, Andreea (Gustave Roussy Cancer Campus) ; Taylor, Matthew (Oregon Health & Science University) ; Universitat Autònoma de Barcelona
Anaplastic thyroid carcinoma is an aggressive malignancy that is almost always fatal and lacks effective systemic treatment options for patients with BRAF -wild type disease. As part of a phase I/II study in patients with advanced/metastatic solid tumors, patients with anaplastic thyroid carcinoma were treated with spartalizumab, a humanized monoclonal antibody against the programmed death-1 (PD-1) receptor. [...]
2020 - 10.1200/JCO.19.02727
Journal of Clinical Oncology, Vol. 38 Núm. 23 (may 2020) , p. 2620-2627  
2.
6 p, 263.8 KB A multicentre phase II gene expression profiling study of putative relationships between tumour biomarkers and clinical response with erlotinib in non-small-cell lung cancer / Tan, E. H. (National Cancer Centre (Singapur). Department of Medical Oncology) ; Ramlau, Rodryg (Regional Lung Disease Centre (Poznan). Department of Oncology) ; Pluzanska, A. (Regional Oncology Centre (Lodz, Polònia). Oncological Chemotherapy Clinic) ; Kuo, H. -P. (Chang Gung Memorial Hospital (Linkou, Taiwan). Department of Thoracic Medicine) ; Reck, Martin (Hospital Grosshansdorf (Grosshansdorf, Alemanya). Department of Thoracic Oncology) ; Milanowski, J. (Akademia Medyczna w Lublinie (Lublin, Polònia). Department of Pneumology, Oncology and Allergology) ; Au, J. S. -K. (Queen Elizabeth Hospital (Hong Kong). Department of Clinical Oncology) ; Felip, Enriqueta (Hospital Universitari Vall d'Hebron) ; Yang, P. -C. (National Taiwan University Hospital (Taipei, Taiwan)) ; Damyanov, D. (Specialized Hospital for Active Treatment in Oncology (Sofia, Bulgaria)) ; Orlov, S. (Pavlov State Medical University. Research Institute of Pulmonology (Sant Petersburg, Rússia)) ; Akimov, Mikhail (Hoffmann-La Roche (Basel, Suïssa)) ; Delmar, P. (Hoffmann-La Roche (Basel, Suïssa)) ; Essioux, L. (Hoffmann-La Roche (Basel, Suïssa)) ; Hillenbach, C. (Hoffmann-La Roche (Basel, Suïssa)) ; Klughammer, B. (Hoffmann-La Roche (Basel, Suïssa)) ; McLoughlin, P. (Hoffmann-La Roche (Basel, Suïssa)) ; Baselga Torres, Josep, 1959-2021, (Hospital Universitari Vall d'Hebron)
Background: Identification of appropriate markers for predicting clinical benefit with erlotinib in non-small-cell lung cancer (NSCLC) may be able to guide patient selection for treatment. This open-label, multicentre, phase II trial aimed to identify genes with potential use as biomarkers for clinical benefit from erlotinib therapy. [...]
2010
Annals of oncology, Vol. 21, Issue 2 (2010) , p. 217-222  

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.