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15 p, 471.4 KB |
Prodromal phase : Differences in prodromal symptoms, risk factors and markers of vulnerability in first episode mania versus first episode psychosis with onset in late adolescence or adulthood
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Verdolini, Norma (Hospital Clínic i Provincial de Barcelona) ;
Borràs, Roger (Hospital Clínic i Provincial de Barcelona) ;
Sparacino, Giulio (Hospital Clínic i Provincial de Barcelona) ;
Garriga, Marina (Hospital Clínic i Provincial de Barcelona) ;
Sagué-Vilavella, Maria (Hospital Clínic i Provincial de Barcelona) ;
Madero, Santiago (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Palacios-Garrán, Roberto (Hospital Clínic i Provincial de Barcelona) ;
Serra, Maria (Hospital Clínic i Provincial de Barcelona) ;
Forte, Maria Florencia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Salagre, Estela (Hospital Clínic i Provincial de Barcelona) ;
Aedo, Alberto (Hospital Clínic i Provincial de Barcelona) ;
Salgado-Pineda, Pilar (FIDMAG Germanes Hospitalàries Research Foundation) ;
Salvatierra, Irene Montoro (Universitat Rovira i Virgili) ;
Sánchez Gistau, Vanessa (Universitat Rovira i Virgili) ;
Pomarol-Clotet, Edith (FIDMAG Germanes Hospitalàries Research Foundation) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Carvalho, Andre F. (Deakin University) ;
Garcia Rizo, Clemente (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Undurraga, Juan (Instituto Psiquiátrico Dr. J. Horwitz Barak) ;
Reinares, María (Hospital Clínic i Provincial de Barcelona) ;
Martínez-Àran, Anabel (Hospital Clínic i Provincial de Barcelona) ;
Bernardo, Miquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Pacchiarotti, Isabella (Hospital Clínic i Provincial de Barcelona) ;
Amoretti, Silvia (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
This study was aimed at identifying differences in the prodromal symptoms and their duration, risk factors and markers of vulnerability in patients presenting a first episode mania (FEM) or psychosis (FEP) with onset in late adolescence or adulthood in order to guide tailored treatment strategies. [...]
2022 -  10.1111/acps.13415
Acta psychiatrica Scandinavica, Vol. 146 (february 2022) , p. 36-50
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21 p, 2.6 MB |
Repurposing Disulfiram as an Antifungal Agent : Development of a New Disulfiram Vaginal Mucoadhesive Gel
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Lajarin-Reinares, Maria (Reig Jofre Laboratories) ;
Naveira-Souto, Iria (Reig Jofre Laboratories) ;
Mallandrich, Mireia (Universitat de Barcelona. Departament de Farmàcia) ;
Suñer-Carbó, Joaquim (Universitat de Barcelona. Departament de Farmàcia) ;
Llagostera Casas, Montserrat (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Calvo Torras, Ma. de los Ángeles (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Fernandez-Campos, Francisco (Labiana Pharmaceuticals)
Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative to treat vaginal candidiasis. [...]
2023 - 10.3390/pharmaceutics15051436
Pharmaceutics, Vol. 15 (may 2023)
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14 p, 982.6 KB |
Repurposing Disulfiram as an Antimicrobial Agent in Topical Infections
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Lajarin-Reinares, Maria (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pena-Rodríguez, Eloy (Topical & Oral Development. Research and Development Reig Jofre Laboratories) ;
Cañellas-Santos, Mariona (Biotechnology Department. Research and Development Reig Jofre Laboratories) ;
Rosell-Vives, E. (Biotechnology Department. Research and Development Reig Jofre Laboratories) ;
Cortés Garmendia, M. Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Casas, M.L. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Calvo Torras, Ma. de los Ángeles (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Fernandez-Campos, Francisco (Topical & Oral Development. Research and Development Reig Jofre Laboratories)
Antimicrobial drugs applied topically offer several advantages. However, the widespread use of antibiotics has led to increasing antimicrobial resistance. One interesting approach in the drug discovery process is drug repurposing. [...]
2022 - 10.3390/antibiotics11121752
Antibiotics, Vol. 11 Núm. 12 (december 2022) , p. 1752
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16 p, 337.3 KB |
High incidence of PTSD diagnosis and trauma-related symptoms in a trauma exposed bipolar I and II sample
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Hogg, Bridget (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Valiente-Gómez, Alicia (Centro de Investigación Biomédica en Red de Salud Mental) ;
Redolar-Ripoll, Diego (Universitat Oberta de Catalunya) ;
Gardoki-Souto, Itxaso (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fontana-McNally, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lupo, Walter (Parc de Salut MAR de Barcelona) ;
Jiménez, Esther (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Madre Rull, Mercè (FIDMAG Germanes Hospitalàries Research Foundation) ;
Blanco Presas, Laura (Universitat de Barcelona. Institut de Neurociències) ;
Reinares, María (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cortizo, Romina (Parc de Salut MAR de Barcelona) ;
Massó-Rodriguez, Anna (Parc de Salut MAR de Barcelona) ;
Castaño, Juan (Parc de Salut MAR de Barcelona) ;
Argila-Plaza, Isabel (FIDMAG Germanes Hospitalàries Research Foundation) ;
Castro-Rodríguez, José Ignacio (Parc de Salut MAR de Barcelona) ;
Comes, Mercè (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Doñate, Marta (Parc Sanitari Sant Joan de Deu) ;
Herrería, Elvira (Hospital Benito Menni-CASM, Sant Boi de Llobregat) ;
Macias, Cristina (Parc de Salut MAR de Barcelona) ;
Mur, Estanislao (Parc de Salut MAR de Barcelona) ;
Novo, Patricia (Parc de Salut MAR de Barcelona) ;
Rosa, Adriane R. (Federal University of Rio Grande doSul) ;
Vieta, Eduard (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Radua, Joaquim (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Padberg, Frank (Klinikum der Universität München) ;
Pérez-Solà, Victor (Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida) ;
Moreno Alcázar, Ana (Centro de Investigación Biomédica en Red de Salud Mental) ;
Amann, Benedikt L. (Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida)
Post-traumatic stress disorder (PTSD) is an established comorbidity in Bipolar Disorder (BD), but little is known about the characteristics of psychological trauma beyond a PTSD diagnosis and differences in trauma symptoms between BD-I and BD-II. [...]
2022 - 10.3389/fpsyt.2022.931374
Frontiers in psychiatry, Vol. 13 (october 2022)
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16 p, 1.6 MB |
The Efficacy and Biopharmaceutical Properties of a Fixed-Dose Combination of Disulfiram and Benzyl Benzoate
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Lajarin-Reinares, Maria (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Martinez-Esteve, Elia (Reig Jofre Laboratories) ;
Pena-Rodríguez, Eloy (Reig Jofre Laboratories) ;
Cañellas-Santos, Mariona (Reig Jofre Laboratories) ;
Bulut, Sanja (Bioglan AB) ;
Karabelas, Kostas (Bioglan AB) ;
Clauss, Adam (Bioglan AB) ;
Nieto, Carles (Reig Jofre Laboratories) ;
Mallandrich, Mireia (Universitat de Barcelona. Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica) ;
Fernandez-Campos, Francisco (Reig Jofre Laboratories)
Scabies and hair lice are parasitic diseases that affect human skin and hair, respectively. The incidence and resistances of these infections are increasing. Tenutex ® (disulfiram and benzyl benzoate emulsion) is an alternative to standard insecticides to avoid resistances. [...]
2022 - 10.3390/ijms231810969
International journal of molecular sciences, Vol. 23, Issue 18 (September 2022) , art. 10969
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10 p, 476.6 KB |
Eye movement desensitization and reprocessing therapy versus supportive therapy in affective relapse prevention in bipolar patients with a history of trauma : study protocol for a randomized controlled trial
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Moreno Alcázar, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Radua, Joaquim (FIDMAG Germanes Hospitalàries Research Foundation) ;
Landin-Romero, Ramon (Neuroscience Research Australia) ;
Blanco Presas, Laura (Benito Menni Complex Assistencial en Salut Mental, Sant Boi de Llobregat) ;
Madre Rull, Mercè (Benito Menni Complex Assistencial en Salut Mental, Sant Boi de Llobregat, Spain) ;
Reinares, María (Hospital Clínic i Provincial de Barcelona) ;
Comes, Mercè (Hospital Clínic i Provincial de Barcelona) ;
Jiménez, Esther (Hospital Clínic i Provincial de Barcelona) ;
Crespo, José Manuel (Centro de Investigación Biomédica en Red de Salud Mental) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Pérez Solà, Víctor (Centre Forum Research Unit, Institute of Neuropsychiatry and Addictions (INAD) Hospital del Mar) ;
Novo, Patricia (Centre Forum Research Unit, Institute of Neuropsychiatry and Addictions (INAD) Hospital del Mar) ;
Doñate, Marta (Centre Forum Research Unit, Institute of Neuropsychiatry and Addictions (INAD) Hospital del Mar) ;
Cortizo, Romina (Centre Forum Research Unit, Institute of Neuropsychiatry and Addictions (INAD) Hospital del Mar) ;
Valiente-Gómez, Alicia (Centre Forum Research Unit, Institute of Neuropsychiatry and Addictions (INAD) Hospital del Mar) ;
Lupo, Walter (Clínica Logos, Barcelona) ;
McKenna, Peter J. (FIDMAG Germanes Hospitalàries Research Foundation) ;
Pomarol-Clotet, Edith (FIDMAG Germanes Hospitalàries Research Foundation) ;
Amann, Benedikt L. (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Up to 60% of patients with bipolar disorder (BD) have a history of traumatic events, which is associated with greater episode severity, higher risk of comorbidity and higher relapse rates. Trauma-focused treatment strategies for BD are thus necessary but studies are currently scarce. [...]
2017 - 10.1186/s13063-017-1910-y
Trials, Vol. 18 (april 2017)
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