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123 p, 2.1 MB Mechanisms of resistance to T-DM1 in HER2-positive breast cancer / Zhang, Junjie, autor. ; Arribas, Joaquín V. (Vicente), supervisor acadèmic. ; Rodilla Benito, Verónica, supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular.
El cáncer de mama HER2-positivo representa alrededor del 15-30% del total de pacientes con cáncer de mama. Este subtipo tiene un mal pronóstico, seguido del subtipo Triple-negativo (TNBC), que lo tiene aún peor. [...]
HER2-positive breast cancer represents around 15-30% of the breast cancer patients. This breast cancer subtype has poor prognosis, followed by the triple negative subtype, which has the worse. Several drugs are currently approved for HER2-positive breast cancer, such as Trastuzumab, Lapatinib and T-DM1. [...]

[Bellaterra] : Universitat Autònoma de Barcelona, 2018.  

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