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9 p, 4.2 MB |
Unleashing inkjet-printed nanostructured electrodes and battery-free potentiostat for the DNA-based multiplexed detection of SARS-CoV-2 genes
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Rossetti, Marianna (Institut Català de Nanociència i Nanotecnologia) ;
Srisomwat, Chawin (Chulalongkorn University. Department of Chemistry) ;
Urban, Massimo (Universitat Autònoma de Barcelona) ;
Rosati, Giulio (Institut Català de Nanociència i Nanotecnologia) ;
Maroli, Gabriel (Institut Català de Nanociència i Nanotecnologia) ;
Yaman Akbay, Hatice Gödze (Institut Català de Nanociència i Nanotecnologia) ;
Chailapakul, Orawon (Chulalongkorn University. Department of Chemistry) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Following the global COVID-19 pandemic triggered by SARS-CoV-2, the need for rapid, specific and cost-effective point-of-care diagnostic solutions remains paramount. Even though COVID-19 is no longer a public health emergency, the disease still poses a global threat leading to deaths, and it continues to change with the risk of new variants emerging causing a new surge in cases and deaths. [...]
2024 -  10.1016/j.bios.2024.116079
Biosensors & bioelectronics, Vol. 250 (April 2024) , art. 116079
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2.
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46 p, 703.3 KB |
Integrated optical devices for lab-on-a-chip biosensing applications
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Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ;
Alvarez, Mar (Institut Català de Nanociència i Nanotecnologia) ;
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
The application of portable, easy-to-use and highly sensitive lab-on-a-chip biosensing devices for real-time diagnosis could offer significant advantages over current analytical methods. Integrated optics-based biosensors have become the most suitable technology for lab-on-chip integration due to their ability for miniaturization, their extreme sensitivity, robustness, reliability, and their potential for multiplexing and mass production at low cost. [...]
2012 - 10.1002/lpor.201100025
Laser & photonics reviews, Vol. 6, Issue 4 (July 2012) , p. 463-487
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3.
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Development of molecular lateral flow biosensors for non-covered medical needs
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Rubio Monterde, Ana ;
Quesada Gonzalez, Daniel, dir. ;
Merkoçi, Arben, dir.
La pandèmia actual de SARS-CoV-2 ha ressaltat la importància de poder desenvolupar, produir i desplegar ràpidament proves de diagnòstic per a malalties infeccioses emergents, ja que el SARS-CoV-2 no serà l'última amenaça. [...]
La actual pandemia de SARS-CoV-2 ha resaltado la importancia de poder desarrollar, producir y desplegar rápidamente pruebas de diagnóstico para enfermedades infecciosas emergentes, ya que el SARS-CoV-2 no será la última amenaza. [...]
The ongoing SARS-CoV-2 pandemic has highlighted the importance of being able to develop, produce and deploy rapidly diagnostic tests for emerging infectious diseases, as SARS-CoV-2 will not be the last threat. [...]
2023
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4.
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8 p, 1.3 MB |
Fundamentals and application of voltammetric electronic tongues in quantitative analysis
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Cetó Alsedà, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ;
Pérez, Sandra (Centro Nacional de Microelectrónica) ;
Prieto-Simón, Beatriz (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica, Elèctrica i Automàtica)
Electronic tongues (ETs) are bioinspired analytical tools based on the synergies between (bio)sensors and chemometrics. Through the application of chemometrics, it is possible to infer underlying relationships between the measured analytical signals and the chemical properties of the samples, both for descriptive and predictive purposes, otherwise impossible to decipher. [...]
2022 - 10.1016/j.trac.2022.116765
Trends in analytical chemistry, Vol. 157 (December 2022) , art. 116765
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5.
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Novel methods for the detection of exosomes as biomarkers for non-communicable diseases
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Pallarès-Rusiñol, Arnau ;
Pividori, María Isabel, dir. ;
Martí Ripoll, Mercè, dir.
En aquesta tesi doctoral es presenta el desenvolupament de noves eines per al diagnòstic precoç i el seguiment de malalties no transmissibles. Tot i que existeixen metodologies d'alt rendiment disponibles al mercat per aquest objectiu, l'alt cost i la baixa disponibilitat en entorns de baixos recursos dificulten la seva implementació en centres d'atenció primària dels països en desenvolupament. [...]
En esta esta tesis doctoral se presenta el desarrollo de nuevas herramientas para el diagnóstico precoz y el seguimiento de enfermedades no transmisibles. Aunque existen metodologías de alto rendimiento disponibles en el mercado para conseguir este objetivo, el alto coste y la escasa disponibilidad en entornos de escasos recursos dificultan su implementación en centros de atención primaria de los países en vías de desarrollo. [...]
This doctoral dissertation aims to contribute to the development of new tools for the early diagnosis and monitoring of non-communicable diseases. To achieve this goal, high throughput methodologies are available in the market, but the high cost and low accessibility difficult their implementation in primary healthcare centers in low- and middle-income countries. [...]
2022
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6.
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43 p, 3.4 MB |
Electrochromic biosensors based on screen-printed Prussian Blue electrodes
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Aller Pellitero, Miguel (Institut de Microelectrònica de Barcelona) ;
Fremeau, Joséphine (Centre National de la Recherche Scientifique. Université Bourgogne Franche-Comté. Institut UTINAM) ;
Villa, Rosa (Institut de Microelectrònica de Barcelona) ;
Guirado López, Gonzalo (Universitat Autònoma de Barcelona. Departament de Química) ;
Lakard, Boris (Centre National de la Recherche Scientifique. Université Bourgogne Franche-Comté. Institut UTINAM) ;
Hihn, Jean Yves (Centre National de la Recherche Scientifique. Université Bourgogne Franche-Comté. Institut UTINAM) ;
del Campo, F. Javier (Institut de Microelectrònica de Barcelona)
Prussian Blue (PB)-modified graphite screen-printed electrodes are increasingly being used in electrochemical biosensors. However, they do not allow the observation of the electrochromism of PB. This work presents the construction of PB-based, electrochromic screen-printed biosensors. [...]
2019 - 10.1016/j.snb.2019.03.100
Sensors and actuators. B, Chemical, Vol. 290 (July 2019) , p. 591-597
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7.
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25 p, 6.0 MB |
A self-powered skin-patch electrochromic biosensor
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Santiago, Sara (Universitat Autònoma de Barcelona) ;
Río-Colín, Diego (Universidad del País Vasco) ;
Azizkhani, Haniyeh (Universitat Autònoma de Barcelona) ;
Aller Pellitero, Miguel (Johns Hopkins University School of Medicine) ;
Guirado López, Gonzalo (Universitat Autònoma de Barcelona) ;
del Campo, F. Javier (Institut de Microelectrònica de Barcelona)
One of the limitations of many skin-patch wearable sensors today is their dependence on silicon-based electronics, increasing their complexity and unit cost. Self-powered sensors, in combination with electrochromic materials, allow simplifying the construction of these devices, leading to powerful analytical tools that remove the need for external detection systems. [...]
2021 - 10.1016/j.bios.2020.112879
Biosensors & bioelectronics, Vol. 175 (March 2021) , art. 112879
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8.
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6.6 MB |
Nanophotonic point-of-care biosensors for innovative clinical diagnosis of respiratory diseases
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Calvo Lozano, Olalla ;
Lechuga, Laura M, dir. ;
Villaverde Corrales, Antonio, dir.
Els mètodes convencionals per al diagnòstic de les malalties respiratòries es basen principalment en les proves clíniques per imatge. Complementar aquesta anàlisi amb una avaluació molecular pot proporcionar un diagnòstic més adequat i complet. [...]
Los métodos convencionales para el diagnóstico de las enfermedades respiratorias se basan principalmente en las pruebas clínicas por imagen. Complementar este análisis con una evaluación molecular puede proporcionar un diagnóstico más adecuado y completo. [...]
The conventional methods for the diagnosis of respiratory diseases rely mainly on the clinical evidence by imaging. Complementing such analysis with a molecular evaluation can provide a more suitable and exhaustive diagnosis. [...]
2022
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10.
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12 p, 1.7 MB |
A Programmable electrochemical Y-shaped DNA scaffold sensor for the single-step detection of antibodies and proteins in untreated biological fluids
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Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Bonini, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Álvarez Diduk, Ruslan (Institut Català de Nanociència i Nanotecnologia) ;
Di Francesco, Fabio (Università degli Studi di Pisa. Dipartimento di Chimica e Chimica Industriale) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Proteins and antibodies are key biomarkers for diagnosing and monitoring specific medical conditions. Currently, gold standard techniques used for their quantification require laborious multi-step procedures, involving high costs and slow response times. [...]
2022 - 10.1002/adfm.202201881
Advanced functional materials, Vol. 32, issue 37 (Sep. 2022) , art. 2201881
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