UAB Digital Repository of Documents 10 records found  Search took 0.01 seconds. 
1.
24 p, 6.0 MB Using Single-Voxel Magnetic Resonance Spectroscopy Data Acquired at 1.5T to Classify Multivoxel Data at 3T : A Proof-of-Concept Study / Ungan, Gulnur Semahat (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pons-Escoda, Albert (Institut d'Investigació Biomèdica de Bellvitge) ; Ulinic, Daniel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Vellido, Alfredo (Centro de Investigación Biomédica en Red) ; Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
In vivo magnetic resonance spectroscopy (MRS) has two modalities, single-voxel (SV) and multivoxel (MV), in which one or more contiguous grids of SVs are acquired. Purpose: To test whether MV grids can be classified with models trained with SV. [...]
2023 - 10.3390/cancers15143709
Cancers, Vol. 15, Issue 14 (July 2023) , art. 3709  
2.
2 p, 1.4 MB Oncolytic virotherapies against glioblastoma multiforme / Montané Gil, Paula ; Universitat Autònoma de Barcelona. Facultat de Biociències
Currently, standard therapy for GBM consists of tumour resection followed by radiotherapy and concomitant TMZ which remains insufficient to mitigate the disease's deadly effects. Therefore, it has been promoted the development of alternate immunotherapies, such as oncolytic virotherapies, that are emerging as a safe and feasible treatments for a variety of malignancies.
2022
Grau en Biotecnologia [815]  
3.
1 p, 2.3 MB IMP2 targeting in notch-high glioblastoma stem cells as a therapteutic approach for glioblastoma multiforme / Khomenko Khomenko, Oleksandra ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Ciències Biomèdiques [832]  
4.
266 p, 7.0 MB Towards improvement of preclinical glioblastoma management : detection, therapy and assessment of response using magnetic resonance techniques / Arias-Ramos, Nuria ; Arús i Caraltó, Carles, dir. ; Candiota Silveira, Ana Paula, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
El Glioblastoma (GB) es el tumor primario agresivo más común, con mal pronóstico y sin cura actualmente. Aunque se aplique tratamiento agresivo (quimioterapia con Temozolamida, TMZ, y radioterapia) generalmente hay recidiva. [...]
Glioblastoma (GB) is the most common and aggressive primary brain tumour with poor prognosis and survival, with no cure available at present. Relapse usually takes place in a short time even after aggressive standard treatment (chemotherapy with Temozolomide, TMZ and radiotherapy). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  
5.
180 p, 5.6 MB Unraveling CK2 inhibition and temozolomide contribution to therapy response in preclinical GL261 glioblastoma: immune system implications and magnetic resonance based nosological imaging / Villamañán de Santiago, Lucía ; Candiota Silveira, Ana Paula, dir. ; Plana i Coll, Maria, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
El glioblastoma (GB) es el tumor primario más común en adultos. Debido a su mal prognóstico, es urgente encontrar mejoras en su tratamiento. El objetivo de esta tesis es estudiar el efecto de inhibidores de CK2 y del agente alquilante Temozolamida (TMZ) a la respuesta a terapia en el modelo de GB preclínico GL261 utilizando tanto métodos in vitro (línea celular GL261) como in vivo (ratones GL261 con tumores). [...]
Glioblastoma is the most common primary brain tumor in adults with a very poor prognosis, for which urgent improvements in treatment are needed. The aim of this thesis was to unravel the contribution of the CK2 inhibitors and the alkylating agent Temozolomide (TMZ) to therapy response in the preclinical glioblastoma (GB) murine model GL261 using in vitro (GL261 cell line) and in vivo (GL261 tumor bearing mice) approaches. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  
6.
184 p, 2.6 MB Efectos de los corticoides en el perfil metabólico, en la evolución y el pronóstico de los pacientes con glioblastoma / Narváez Martínez, Yislenz Yaderliz ; Balañá, Carmen, dir. ; Barco Berrón, Sonia del, dir. ; Feliu Frasnedo, Evarist, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Introducción El Glioblastoma (GBM) es el tumor maligno primario del Sistema Nervioso Central (SNC) más frecuente. La incidencia oscila entre 3 - 4 x 100. 000 habitantes/año. La supervivencia media es 6 a 16 meses. [...]
Introduction Glioblastoma (GBM) is the most common type of primary malignant tumor of the Central Nervous System (CNS). The Incidence ranges 3 - 4 x 100. 000 inhabitants/year. The mean survival is 6 to 16 months. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2018.  
7.
10 p, 2.5 MB A TRPV2 interactome-based signature for prognosis in glioblastoma patients / Doñate-Macian, Pablo (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Gómez Moruno, Antonio (Centre de Regulació Genòmica) ; Degano, Irene R. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Peralvarez-Marin, Alex (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Proteomics aids to the discovery and expansion of protein-protein interaction networks, which are key to understand molecular mechanisms in physiology and physiopathology, but also to infer protein function in a guilt-by-association fashion. [...]
2018 - 10.18632/oncotarget.24843
Oncotarget, Vol. 9, Num. 26 (April 2018) , p. 18400-18409  
8.
1 p, 2.9 MB From adult neurogenesis to the gliomagenic potential of the subventricular zone : glioma stem cell maintenance in the context of the hypoxic niche : the case of glioblastoma multiforme / Capdevila, Claudia ; Martí-Clúa, Joaquín, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
9.
14 p, 1.1 MB A Novel Semi-Supervised Methodology for Extracting Tumor Type-Specific MRS Sources in Human Brain Data / Ortega-Martorell, Sandra (Liverpool John Moores University. Department of Mathematics and Statistics) ; Ruiz, Héctor (Liverpool John Moores University. Department of Mathematics and Statistics) ; Vellido, Alfredo (Universitat Politècnica de Catalunya. Departament de Llenguatges i Sistemes Informàtics) ; Olier, Iván (University of Manchester. Institute of Population Health) ; Romero, Enrique (Universitat Politècnica de Catalunya. Departament de Llenguatges i Sistemes Informàtics) ; Julià Sapé, Ma. Margarita (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Martín, José D. (Universitat de València. Departament d'Enginyeria Electrònica) ; Jarman, Ian H. (Liverpool John Moores University. Department of Mathematics and Statistics) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Lisboa, Paulo J. G. (Liverpool John Moores University. Department of Mathematics and Statistics) ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Background: the clinical investigation of human brain tumors often starts with a non-invasive imaging study, providing information about the tumor extent and location, but little insight into the biochemistry of the analyzed tissue. [...]
2013 - 10.1371/journal.pone.0083773
PloS one, Vol. 8 Issue 12 (December 2013) , p. e83773  
10.
1 p, 4.6 MB Tractaments per al glioblastoma multiforme / Canals Florit, Ricard ; Saura Antolín, Carlos, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Bioquímica [814]  

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