UAB Digital Repository of Documents 7 records found  Search took 0.01 seconds. 
1.
11 p, 4.2 MB Neuregulin 1 Reduces Motoneuron Cell Death and Promotes Neurite Growth in an in Vitro Model of Motoneuron Degeneration / Mòdol Caballero, Guillem (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos, Daniel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, Xavier (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Herrando-Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències)
Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with no effective treatment currently available. Although the mechanisms of motoneuron (MN) death are still unclear, glutamate excitotoxicity and neuroinflammatory reaction are two main features in the neurodegenerative process of ALS. [...]
2018 - 10.3389/fncel.2017.00431
Frontiers in cellular neuroscience, Vol. 11 (january 2018)  
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2 p, 165.1 KB Editorial - Glial Cells : Managers of Neuro-Immunity / Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Guillemin, Gilles J. (Macquarie University. Department of Biomedical Sciences) ; Curtin, James F. (Dublin Institute of Technology. School of Food Science & Environmental Health) ; Zirger, Jeffrey M. (U.S. Centers for Disease Control and Prevention) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
After many decades of study in the field of Neuroscience that were mostly centered on the neuron there is a mounting interest in the study of the function of the glial cells in many aspects and functions of the central nervous system. [...]
2016 - 10.3389/fncel.2016.00060
Frontiers in cellular neuroscience, Vol. 10 (March 2016) , art.60  
3.
10 p, 1.8 MB Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer's disease / González-Marrero, Ibrahim (Universidad de La Laguna. Departamento de Anatomía Humana) ; Giménez Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Johanson, Conrad E. (Alpert Medical School at Brown University. Department of Neurosurgery) ; Carmona-Calero, Emilia María (Universidad de La Laguna. Departamento de Anatomía Humana) ; Castañeyra-Ruiz, Leandro (Universidad de La Laguna. Departamento de Anatomía Humana) ; Brito-Armas, José Miguel (Universidad de La Laguna. Departamento de Psicología) ; Castañeyra-Perdomo, Agustín (Universidad de La Laguna. Departamento de Anatomía Humana) ; Castro-Fuentes, Rafael (Universidad de La Laguna. Departamento de Psicología) ; Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal
Compromised secretory function of choroid plexus (CP) and defective cerebrospinal fluid (CSF) production, along with accumulation of beta-amyloid (Aβ) peptides at the blood-CSF barrier (BCSFB), contribute to complications of Alzheimer's disease (AD). [...]
2015 - 10.3389/fncel.2015.00017
Frontiers in cellular neuroscience, Vol. 9 (February 2015) , art. 17  
4.
12 p, 418.6 KB Are microglial cells the regulators of lymphocyte responses in the CNS? / Almolda Ardid, Beatriz (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; González, Berta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Castellano López, Bernardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The infiltration of immune cells in the central nervous system is a common hallmark in different neuroinflammatory conditions. Accumulating evidence indicates that resident glial cells can establish a cross-talk with infiltrated immune cells, including T-cells, regulating their recruitment, activation and function within the CNS. [...]
2015 - 10.3389/fncel.2015.00440
Frontiers in cellular neuroscience, Vol. 16 Núm. 9 (November 2015) , Article ID 440  
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14 p, 2.8 MB Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's disease / Saura Antolín, Carlos A. (Carlos Alberto) (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Parra Damas, Arnaldo J. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Enríquez-Barreto, Lilian (Universitat Autònoma de Barcelona. Institut de Neurociències)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by abnormal accumulation of β-amyloid and tau and synapse dysfunction in memory-related neural circuits. Pathological and functional changes in the medial temporal lobe, a region essential for explicit memory encoding, contribute to cognitive decline in AD. [...]
2015 - 10.3389/fncel.2015.00318
Frontiers in cellular neuroscience, Vol. 9 Núm. 318 (2015)  
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10 p, 2.3 MB Imaging the microanatomy of astrocyte-T-cell interactions in immune-mediated inflammation / Barcia, Carlos (Consorci Hospital General Universitari (Valencia). Departament de Neurocirurgia) ; Mitxitorena, Izaskun (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Carrillo-de Sauvage, Maria A. (Institut d'Imagerie Biomédicale) ; Gallego, José Maria (Consorci Hospital General Universitari (Valencia). Departament de Neurocirurgia) ; Pérez-Vallés, Ana (Consorci Hospital General Universitari (Valencia). Departament de Patologia) ; Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències)
The role of astrocytes in the immune-mediated inflammatory response in the brain is more prominent than previously thought. Astrocytes become reactive in response to neuro-inflammatory stimuli through multiple pathways, contributing significantly to the machinery that modifies the parenchymal environment. [...]
2013 - 10.3389/fncel.2013.00058
Frontiers in cellular neuroscience, Vol. 7 (April 2013) , p. 1-10  
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11 p, 3.3 MB Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons / Mòdol, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Alé, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease manifested by progressive muscle atrophy and paralysis due to the loss of upper and lower motoneurons (MN). Spasticity appears in ALS patients leading to further disabling consequences. [...]
2014 - 10.3389/fncel.2014.00007
Frontiers in cellular neuroscience, Vol. 8 Núm. 7 (Jan. 2014) , p. 1-11  

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