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1.
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10 p, 482.9 KB |
Improved adipose tissue function with initiation of protease inhibitor-only ART
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Maughan, Robert T. (University College Dublin) ;
Feeney, Eoin R. (University College Dublin) ;
Capel, Emilie (Sorbonne Universities) ;
Capeau, Jacqueline (Sorbonne Universities) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Giralt, Marta (CIBER Fisiopatologia de la Obesidad y Nutrición) ;
Lange, Joep M.A. (Thai Red Cross Aids Research Center (TRCARC)) ;
Phanuphak, Praphan (Chulalongkorn University) ;
Cooper, David A. (University of New South Wales) ;
Reiss, Peter (Thai Red Cross Aids Research Center (TRCARC)) ;
Mallon, Patrick W.G. (University College Dublin) ;
Autar, Saskia R. ;
van der Lugt, Jasper ;
Avihingsanon, Anchalee ;
Klungklang, Supalak ;
Ubolyam, Sasiwimol ;
Universitat Autònoma de Barcelona
Use of ART containing HIV PIs has previously been associated with toxicity in subcutaneous adipose tissue (SAT), potentially contributing to the development of lipodystrophy and insulin resistance. However, the effect of PIs on SAT function in ART-naive patients independent of other ART classes is unknown. [...]
2016 -  10.1093/jac/dkw301
Journal of antimicrobial chemotherapy, Vol. 71 Núm. 11 (january 2016) , p. 3212-3221
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2.
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35 p, 396.5 KB |
Faecal phageome of healthy individuals : Presence of antibiotic resistance genes and variations caused by ciprofloxacin treatment
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Fernandez-Orth, Dietmar (Barcelona Institute for Global Health (ISGlobal)) ;
Miró, Elisenda (Institut d'Investigació Biomèdica Sant Pau) ;
Brown-Jaque, Maryury (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Rodríguez-Rubio, Lorena (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Espinal, Paula (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rodríguez-Navarro, Judith (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
González-López, Juanjo 1975- (Hospital Universitari Vall d'Hebron) ;
Muniesa, Maite (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Navarro Risueño, Ferran (Institut d'Investigació Biomèdica Sant Pau)
Objectives: Antimicrobial resistance genes (ARGs) can be transferred by means of mobile genetic elements, which play a critical role in the dissemination of resistance in the bacterial community. ARG transmission within mobile genetic elements has been reported in plasmids and transposons but less frequently in bacteriophages. [...]
2019 - 10.1093/jac/dky540
Journal of antimicrobial chemotherapy, Vol. 74, Issue 4 (April 2019) , p. 854-864
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3.
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8 p, 576.9 KB |
Increasing trend of antimicrobial resistance in Shigella associated with MSM transmission in Barcelona, 2020-21 : outbreak of XRD Shigella sonnei and dissemination of ESBL-producing Shigella flexneri
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Moreno-Mingorance, Albert (Hospital Universitari Vall d'Hebron) ;
Mir-Cros, Alba (Hospital Universitari Vall d'Hebron) ;
Goterris, Lidia (Hospital Universitari Vall d'Hebron) ;
Rodríguez Garrido, Virginia (Hospital Universitari Vall d'Hebron) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron) ;
Barberà, Maria Jesús (Hospital Universitari Vall d'Hebron) ;
Alberny, Mireia (Institut Català de la Salut) ;
Hoyos, Y. (Hospital Universitari Vall d'Hebron) ;
Descalzo, Vicente (Institut Català de la Salut) ;
Bravo, Albert (Hospital Universitari Vall d'Hebron) ;
Roca Grande, Josep (Hospital Universitari Vall d'Hebron) ;
Viñado, Belén (Hospital Universitari Vall d'Hebron) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Larrosa, María Nieves (Hospital Universitari Vall d'Hebron) ;
González-López, Juanjo 1975- (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Several countries have recently reported the detection of ESBL-producing Shigella sonnei associated with transmission among MSM. In a previous study by our group, 2. 8% of Shigella spp. obtained from MSM in Barcelona between 2015 and 2019 were ESBL producers. [...]
2023 - 10.1093/jac/dkad031
Journal of antimicrobial chemotherapy, Vol. 78 (february 2023) , p. 975-982
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4.
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8 p, 301.2 KB |
Macrolide resistance and molecular typing of Mycoplasma pneumoniae infections during a 4 year period in Spain
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Rivaya, Belén (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Jordana-Lluch, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Fernandez Rivas, Gema (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Molinos, Sònia (Laboratori Clìnic Metropolitana Nord) ;
Campos, Roi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Méndez-Hernández, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Matas, Lurdes (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Mycoplasma pneumoniae (MP) causes community-acquired pneumonia affecting mainly children, and tends to produce cyclic outbreaks. The widespread use of macrolides is increasing resistance rates to these antibiotics. [...]
2020 - 10.1093/jac/dkaa256
Journal of antimicrobial chemotherapy, Vol. 75 (july 2020) , p. 2752-2759
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5.
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12 p, 653.9 KB |
HIV-1 Gag mutations alone are sufficient to reduce darunavir susceptibility during virological failure to boosted PI therapy
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Blanch-Lombarte, Oscar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santos, José Ramón (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Peña, Ruth (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Jiménez Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Prado, Julia G. (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Virological failure (VF) to boosted PIs with a high genetic barrier is not usually linked to the development of resistance-associated mutations in the protease gene. From a cohort of 520 HIV-infected subjects treated with lopinavir/ritonavir or darunavir/ritonavir monotherapy, we retrospectively identified nine patients with VF. [...]
2020 - 10.1093/jac/dkaa228
Journal of antimicrobial chemotherapy, Vol. 75 (june 2020) , p. 2535-2546
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6.
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11 p, 635.6 KB |
P-glycoprotein (ABCB1) activity decreases raltegravir disposition in primary CD4+P-gp high cells and correlates with HIV-1 viral load
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Minuesa, Gerard (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Arimany-Nardi, Cristina (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Cedeño, Samandhy (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Moltó Marhuenda, José (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ;
Clotet Sala, Bonaventura (Institució Catalana de Recerca i Estudis Avançats) ;
Pastor-Anglada, Marçal (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Martínez Picado, Francisco Javier (Universitat de Vic - Universitat Central de Catalunya)
To evaluate the role of P-glycoprotein (P-gp) and multidrug-resistant-protein 1 (MRP1) on raltegravir intracellular drug disposition in CD4+ T cells, investigate the effect of HIV-1 infection on P-gp expression and correlate HIV-1 viraemia with P-gp activity in primary CD4+ T cell subsets. [...]
2016 - 10.1093/jac/dkw215
Journal of antimicrobial chemotherapy, Vol. 71 (june 2016) , p. 2782-2792
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7.
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11 p, 354.4 KB |
Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART : a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing
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Cozzi-Lepri, Alessandro (University College London) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Di Giallonardo, Francesca (University Hospital Zurich (Suïssa)) ;
Schuurman, Rob (Department of Virology. University Medical Centre, Utrecht) ;
Däumer, Martin (Institut für Immunologie und Genetik, Kaiserslautern, Germany) ;
Aitken, Sue (Department of Virology. University Medical Centre, Utrecht) ;
Ceccherini-Silberstein, Francesca (Department of Experimental Medicine and Surgery, University of Rome Tor Vergata) ;
D'Arminio Monforte, Antonella (Clinic of Infectious Diseases, 'San Paolo' Hospital) ;
Geretti, Anna Maria (Institute of Infection & Global Health, University of Liverpool) ;
Booth, Clare L. (Department of Virology, Royal Free London NHS Foundation Trust) ;
Kaiser, Rolf (Institute of Virology, University of Cologne) ;
Michalik, Claudia (Competence Network for HIV/AIDS, Bochum, Germany) ;
Jansen, Klaus (Competence Network for HIV/AIDS, Bochum, Germany) ;
Masquelier, Bernard (Université Bordeaux 2) ;
Bellecave, Pantxika (Université Bordeaux 2) ;
Kouyos, Roger D. (University Hospital Zurich (Suïssa)) ;
Castro, Erika (Centre Hospitalier Universitaire Vaudois (Lausanne, Suïssa). Service of Community Psychiatry) ;
Furrer, Hansjakob (Bern University Hospital) ;
Schultze, Anna (University College London) ;
Günthard, Huldrych F. (University Hospital Zurich (Suïssa)) ;
Brun-Vezinet, Francoise (Department of Virology, Bichat University Hospital, Paris) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Metzner, Karin J. (University Hospital Zurich (Suïssa)) ;
CHAIN Minority HIV-1 Variants Working Group
It is still debated if pre-existing minority drug-resistant HIV-1 variants (MVs) affect the virological outcomes of first-line NNRTI-containing ART. This Europe-wide case-control study included ART-naive subjects infected with drug-susceptible HIV-1 as revealed by population sequencing, who achieved virological suppression on first-line ART including one NNRTI. [...]
2014 - 10.1093/jac/dku426
Journal of antimicrobial chemotherapy, Vol. 70 (october 2014) , p. 930-940
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