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UAB Digital Repository of Documents	2 records found	Search took 0.00 seconds.

35 p, 10.2 MB

Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders / Segal, Ashlea (Monash University) ; Parkes, Linden (Rutgers University. Department of Psychiatry) ; Aquino, Kevin (BrainKey (Estats Units d'Amèrica)) ; Kia, Seyed Mostafa (Tilburg University. Department of Cognitive Science and Artificial Intelligence) ; Wolfers, Thomas (University of Tübingen. Department of Psychiatry and Psychotherapy) ; Franke, Barbara (Radboud University Medical Center. Department of Human Genetics) ; Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics) ; Beckmann, Christian F. (University of Oxford. Nuffield Department of Clinical Neurosciences) ; Westlye, Lars T. (University of Oslo) ; Andreassen, Ole A. (University of Oslo) ; Zalesky, Andrew (The University of Melbourne. Department of Biomedical Engineering) ; Harrison, Ben J. (The University of Melbourne. Department of Psychiatry) ; Davey, Christopher (University of Melbourne. Department of Psychiatry) ; Soriano-Mas, Carles (Universitat de Barcelona. Department of Social Psychology and Quantitative Psychology) ; Cardoner, N. (Narcís) (Universitat Autònoma de Barcelona) ; Tiego, Jeggan (Monash University) ; Yücel, Murat (QIMR Berghofer Medical Research Institute (Austràlia)) ; Braganza, Leah (Monash University) ; Suo, Chao (Monash eResearch Centre (Austràlia)) ; Berk, Michael (Florey Institute for Neuroscience and Mental Health) ; Cotton, Sue (University of Melbourne. Centre for Youth Mental Health) ; Bellgrove, Mark A. (Monash University) ; Marquand, Andre F. (King's College London. Department of Neuroimaging) ; Fornito, Alex (Monash University)
The substantial individual heterogeneity that characterizes people with mental illness is often ignored by classical case-control research, which relies on group mean comparisons. Here we present a comprehensive, multiscale characterization of the heterogeneity of gray matter volume (GMV) differences in 1,294 cases diagnosed with one of six conditions (attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, depression, obsessive-compulsive disorder and schizophrenia) and 1,465 matched controls. [...]
2023 - DOI (Digital Object Identifier)

10.1038/s41593-023-01404-6
Nature Neuroscience, Vol. 26 (august 2023) , p. 1613-1629

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28 p, 14.2 MB

Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state / Padilla, Stephanie L. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Qiu, Jian (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Soden, Marta E. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nestor, Casey C. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Barker, Forrest D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Zweifel, Larry S. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Rønnekleiv, Oline K. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Kelly, Martin J. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica))
In the face of starvation, animals will engage in high-risk behaviors that would normally be considered maladaptive. Starving rodents, for example, will forage in areas that are more susceptible to predators and will also modulate aggressive behavior within a territory of limited or depleted nutrients. [...]
2016 - DOI (Digital Object Identifier)

10.1038/nn.4274
Nature neuroscience, Vol. 19, Num. 5 (May 2016) , p. 734-741

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