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14 p, 11.1 MB Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis / Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Herrando-Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Manzano, Raquel (Universidad de Zaragoza) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Osta, Rosario (Universidad de Zaragoza) ; Navarro, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Sporadic and familiar amyotrophic lateral sclerosis (ALS) cases presented lower cholinergic activity than in healthy individuals in their still preserved spinal motoneurons (MNs) suggesting that cholinergic reduction might occur before MN death. [...]
2013 - 10.1002/brb3.104
Brain and behavior, Vol. 3, Núm. 2 (February 2013) , p. 145-158  

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