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1.
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22 p, 1.6 MB |
Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
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Weber, Minéia (Universitat de Barcelona) ;
Mera, Paula (Instituto de Salud Carlos III) ;
Casas, Josefina (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Salvador, Javier (Clínica Universidad de Navarra) ;
Rodríguez, Amaia (Clínica Universidad de Navarra) ;
Alonso, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sebastián, David (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Soler-Vázquez, MCarmen (Universitat de Barcelona) ;
Montironi, Carla (Hospital Clínic i Provincial de Barcelona) ;
Recalde, Sandra (Universitat de Barcelona) ;
Fucho, Raquel (Universitat de Barcelona) ;
Calderon-Dominguez, María (Universitat de Barcelona) ;
Mir, Joan Francesc (Universitat de Barcelona) ;
Bartrons, Ramon (Universitat de Barcelona) ;
Escolà-Gil, Joan Carles (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez-Infantes, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zorzano Olarte, Antonio (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Llorente-Cortes, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ;
Casals, Nuria (Universitat Internacional de Catalunya) ;
Valentí, Victor (Clínica Universidad de Navarra) ;
Frühbeck, Gema (Clínica Universidad de Navarra) ;
Herrero, Laura (Instituto de Salud Carlos III) ;
Serra, Dolors (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high-fat diet (HFD)-induced obesity and NAFLD in mice by enhancing liver fatty acid oxidation (FAO). [...]
2020 -  10.1096/fj.202000678R
FASEB Journal, Vol. 34 Núm. 9 (january 2020) , p. 11816-11837
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2 p, 74.0 KB |
Corrigendum : Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia: A cohort study and ecological analysis
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Català, Martí (University of Oxford) ;
Coma, Ermengol (Institut Català de la Salut) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya) ;
Andrés, Cristina (Hospital Universitari Vall d'Hebron) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Antón, Andrés (Hospital Universitari Vall d'Hebron) ;
Bordoy, Antoni E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fina, Francesc (Institut Català de la Salut) ;
Martró, Elisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Medina, Manuel (Institut Català de la Salut) ;
Mora, Núria (Institut Català de la Salut) ;
Saludes, Verónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prats, Clara (Universitat Politècnica de Catalunya) ;
Prieto-Alhambra, Daniel (University of Oxford) ;
Alvarez-Lacalle, Enrique (Universitat Politècnica de Catalunya) ;
Universitat Autònoma de Barcelona
We aim to compare the severity of infections between omicron and delta variants in 609,352 SARS-CoV-2 positive cases using local hospitalization, vaccination, and variants data from the Catalan Health Care System (which covers around 7. [...]
2022 - 10.3389/fpubh.2022.1060328
Frontiers in Public Health, Vol. 10 (november 2022)
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3.
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13 p, 588.5 KB |
Impact of the implementation of best practice guidelines on nurse's evidence-based practice and on nurses' work environment : Research protocol 实施最佳实践指南对护士循证实践和护士工作环境的影响:研究方案
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Esteban-Sepúlveda, Sílvia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Sesé-Abad, Albert (Universitat de les Illes Balears) ;
Lacueva-Pérez, Laia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Domingo-Pozo, Manuela (Instituto de Investigación Sanitaria y Biomédica de Alicante) ;
Alonso-Fernández, Sergio (Institut Germans Trias i Pujol) ;
Aquilue-Ballarin, Marta (Universitat Jaume I) ;
Barceló-Martínez, Ana Isabel (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
Cristobal-Dominguez, Estíbaliz (Osakidetza IHO Araba) ;
Bujalance-Hoyos, Jesús (Hospital Regional Universitario de Málaga) ;
Dossantos-Sánchez, Consuelo (Hospital Universitario Lucus Augusti (Lugo)) ;
Pascual-Pascual, Manuel Angel (Hospital de Guadarrama) ;
García-Arteaga, Elisabeth (Fundació Hospital de Puigcerdà) ;
Galisteo-Giménez, María (Hospital Clínic i Provincial de Barcelona) ;
Mas Dalmau, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Heredia-Reina, María Pilar (Hospital Universitario de Fuenlabrada ( Madrid)) ;
Roca-Martí, Sílvia (Consorci Sanitari de l'Anoia) ;
Pérez Riart, María (Parc de Salut MAR de Barcelona) ;
Albornos-Muñoz, Laura (Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC)) ;
González-Maria, Esther (Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable) ;
Fernández-Domínguez, Juan Carlos (Universitat de les Illes Balears)
Aim: To determine the impact of the Best Practice Spotlight Organization® initiative on nurses' perception of their work environment and their attitudes to evidence-based practice. Design: Quasi-experimental, multicentre study. [...]
2021 - 10.1111/jan.14598
Journal of Advanced Nursing, Vol. 77 Núm. 1 (january 2021) , p. 448-460
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4.
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22 p, 2.7 MB |
Somatic hypomethylation of pericentromeric sst1 repeats and tetraploidization in human colorectal cancer cells
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González Fernández, Beatriz (Institut Germans Trias i Pujol) ;
Navarro Jiménez, Maria (Institut Germans Trias i Pujol) ;
Alonso De Gennaro, María José (Institut Germans Trias i Pujol) ;
Jansen, Sanne Marcia (Institut Germans Trias i Pujol) ;
Granada, Isabel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Perucho, Manuel (Sanford Burnham Prebys Medical Discovery Institute (SBP)) ;
Alonso, Sergio (Institut Germans Trias i Pujol)
Somatic DNA hypomethylation and aneuploidy are hallmarks of cancer, and there is evidence for a causal relationship between them in knockout mice but not in human cancer. The non-mobile pericentromeric repetitive elements SST1 are hypomethylated in about 17% of human colorectal cancers (CRC) with some 5-7% exhibiting strong age-independent demethylation. [...]
2021 - 10.3390/cancers13215353
Cancers, Vol. 13 Núm. 21 (11-1 2021) , p. 5353
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10 p, 645.3 KB |
The PRISMA 2020 statement : an updated guideline for reporting systematic reviews Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas
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Yepes-Nuñez, J.J. (Hospital Universitario Fundación Santa Fe de Bogotá) ;
Urrútia, Gerard (Institut d'Investigació Biomèdica Sant Pau) ;
Romero-García, M. (Institut d'Investigació Biomèdica de Bellvitge) ;
Alonso-Fernández, Sergio (Institut d'Investigació Biomèdica de Bellvitge)
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. [...]
2021 - 10.1016/j.recesp.2021.06.016
Revista española de cardiología, Vol. 74 Núm. 9 (septiembre 2021) , p. 790-799
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6.
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0 p, 2.5 MB |
Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia : A cohort study and ecological analysis
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Català, Martí (University of Oxford. Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences) ;
Coma, Ermengol (Institut Català de la Salut) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya. Departament de Física) ;
Andrés, Cristina (Instituto de Salud Carlos III) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Antón, Andrés (Instituto de Salud Carlos III) ;
Bordoy, Antoni E. (Instituto de Salud Carlos III) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Fina, Francesc (Institut Català de la Salut) ;
Martró, Elisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Medina, Manuel (Institut Català de la Salut) ;
Mora, Núria (Institut Català de la Salut) ;
Saludes, Verónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prats, Clara (Universitat Politècnica de Catalunya. Departament de Física) ;
Prieto-Alhambra, Daniel (University of Oxford. Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences) ;
Alvarez-Lacalle, Enrique (Universitat Politècnica de Catalunya. Departament de Física)
We aim to compare the severity of infections between omicron and delta variants in 609,352 SARS-CoV-2 positive cases using local hospitalization, vaccination, and variants data from the Catalan Health Care System (which covers around 7. [...]
2022 - 10.3389/fpubh.2022.961030
Frontiers in Public Health, Vol. 10 (August 2022)
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25 p, 2.6 MB |
Modelling the dynamics of tuberculosis lesions in a virtual lung : Role of the bronchial tree in endogenous reinfection
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Català, Martí (Universitat Politècnica de Catalunya. Departament de Física) ;
Bechini Bernad, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tenesa, Montserrat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez Andrés, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Moya, Mariano (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valls, Joaquim (Universitat Politècnica de Catalunya. Departament de Física) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya. Departament de Física) ;
López, Daniel (Universitat Politècnica de Catalunya. Departament de Física) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Prats, Clara (Universitat Politècnica de Catalunya. Departament de Física)
Tuberculosis (TB) is an infectious disease that still causes more than 1. 5 million deaths annually. The World Health Organization estimates that around 30% of the world's population is latently infected. [...]
2020 - 10.1371/journal.pcbi.1007772
PLoS computational biology, Vol. 16 (may 2020)
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21 p, 1.4 MB |
Motherhood and decision-making among women living with HIV in developed countries : a systematic review with qualitative research synthesis
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Huertas-Zurriaga, Ariadna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Palmieri, Patrick A. (Universidad Norbert Wiener. South American Center for Qualitative Research) ;
Edwards, Joan E. (Texas Woman's University. Center for Global Nursing) ;
Cesario, Sandra K. (Texas Woman's University. Center for Global Nursing) ;
Alonso-Fernández, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pardell Dominguez, Lidia (Universitat Autònoma de Barcelona. Departament d'Infermeria) ;
Dominguez-Cancino, Karen A. (Universidad de Chile. Escuela de Salud Pública) ;
Leyva-Moral, Juan M. (Universitat Autònoma de Barcelona. Departament d'Infermeria)
Women living with HIV (WLH) lack evidence-based information about reproductive options while managing pressures from family, clinicians, and communities to give up the idea of having children. As the reproduction intentions of WLH are not well understood, stigmatizing behaviors force them to hide their disease to avoid rejection by their family, partner, and social networks. [...]
2021 - 10.1186/s12978-021-01197-6
Reproductive health, Vol. 18 (july 2021)
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18 p, 2.7 MB |
Empirical model for short-time prediction of COVID-19 spreading
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Català, Martí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya. Departament de Física) ;
Alvarez-Lacalle, Enrique (Universitat Politècnica de Catalunya. Departament de Física) ;
López, Daniel (Universitat Politècnica de Catalunya. Departament de Física) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol) ;
Prats, Clara (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
The appearance and fast spreading of Covid-19 took the international community by surprise. Collaboration between researchers, public health workers, and politicians has been established to deal with the epidemic. [...]
2020 - 10.1371/journal.pcbi.1008431
PLoS computational biology, Vol. 16 Núm. 12 (december 2020) , p. e1008431
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