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1.
10 p, 694.0 KB The ACROSS study : Long-term efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis / Derfuss, Tobias (University Hospital Basel (Basilea, Suïssa)) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron) ; Rodegher, M. (Fondazione Don Carlo Gnocchi) ; Wuerfel, J. (Medical Image Analysis Center Basel) ; Gaetano, Laura (Medical Image Analysis Center Basel) ; Tomic, D. (Novartis Pharma, Basel) ; Azmon, Amin (Novartis Pharma, Basel) ; Wolf, C. (Lycalis sprl) ; Kappos, Ludwig (University Hospital Basel (Basilea, Suïssa)) ; Universitat Autònoma de Barcelona
In chronic diseases such as multiple sclerosis requiring lifelong treatment, studies on long-term outcomes are important. To assess disability and magnetic resonance imaging-related outcomes in relapsing multiple sclerosis patients from a Phase 2 study of fingolimod 10 or more years after randomization and to compare outcomes in patients who had a higher fingolimod exposure versus those with a lower fingolimod exposure. [...]
2020 - 10.1177/2055217320907951
Multiple Sclerosis Journal - Experimental, Translational and Clinical, Vol. 6 (march 2020)  
Detailed record - Creative Commons
2.
10 p, 1.6 MB International sentinel site surveillance of patients with transfusional hemosiderosis treated with deferasirox in actual practice setting / El-Beshlawy, Amal (Cairo University) ; Inusa, Baba (Evelina Children's Hospital) ; Beneitez Pastor, David (Hospital Universitari Vall d'Hebron) ; Xicoy, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Duran Nieto, Maria Soledad (Hospital Materno Infantil de Jaén) ; Bruederle, Andreas (Novartis Pharma AG) ; Azmon, Amin (Novartis Pharma AG, Switzerland) ; Gilotti, Geralyn (Novartis Pharmaceuticals Corporation, USA) ; Elalfy, Mohsen (Ain Shams University (El Caire, Egipte)) ; Universitat Autònoma de Barcelona
Objective:The study evaluates the long-term deferasirox treatment of adult and pediatricpatients with chronic transfusional iron overload in clinical practice. Methods:In this non-interventional study, patients were observed for up to 3 years frominitiation of deferasirox treatment both prospectively and retrospectively for up to 1 yearprior to enrollment. [...]
2019 - 10.1080/16078454.2018.1558758
Hematology, 2019  
Detailed record - Creative Commons

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