Home > Search Results: Bioorganic
  Search Tips
Advanced Search
Search collections:
Sort by: Display results: Output format:
UAB Digital Repository of Documents 4 records found  Search took 0.01 seconds. 
1.
6 p, 2.3 MB Bioconjugated technetium carbonyls by transmetalation reaction with zinc derivatives / Borràs, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Lecina Vicente, Joan (Universitat Autònoma de Barcelona. Departament de Química) ; Foster, Julie (Queen Mary University of London. John Vane Science Centre) ; Kashani, Roxana (Queen Mary University of London. John Vane Science Centre) ; Melendez-Alafort, L. (Istituto Oncologico Veneto IRCCS) ; Sosabowski, Jane (Queen Mary University of London. John Vane Science Centre) ; Suades Ortuño, Joan (Universitat Autònoma de Barcelona. Departament de Química)
The transmetalation reaction between zinc dithiocarbamates functionalized with organic groups and the cation fac-[Tc(HO)(CO)] has been studied as a new strategy to bind biomolecules to this radionuclide for preparing radiopharmaceuticals with high molar activity. [...]
2021 - 10.1016/j.bmcl.2021.127840
Bioorganic and Medicinal Chemistry Letters, Vol. 37 (April 2021) , art. 127840  
Detailed record - Creative Commons
2.
10 p, 748.9 KB Synthesis and biological evaluation of N -cyanoalkyl-, N -aminoalkyl-, and N -guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents / Sola, Irene (Universitat de Barcelona. Institut de Biomedicina) ; Artigas, Albert (Universitat de Barcelona. Institut de Biomedicina) ; Taylor, Martin C. (London School of Hygiene and Tropical Medicine) ; Pérez-Areales, Francisco Javier (Universitat de Barcelona. Institut de Biomedicina) ; Viayna, Elisabet (Universitat de Barcelona. Institut de Biomedicina) ; Clos, M. Victoria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pérez, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Wright, Colin W. (University of Bradford. Bradford School of Pharmacy) ; Kelly, John M. (London School of Hygiene and Tropical Medicine) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Institut de Biomedicina)
Current drugs against human African trypanosomiasis (HAT) suffer from several serious drawbacks. The search for novel, effective, brain permeable, safe, and inexpensive antitrypanosomal compounds is therefore an urgent need. [...]
2016 - 10.1016/j.bmc.2016.08.036
Bioorganic & Medicinal Chemistry, Vol. 24 (november 2016) , p. 5162-5171  
Detailed record - Creative Commons
3.
70 p, 2.1 MB Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors / Di Pietro, Ornella (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Alencar, Nelson (Universitat de Barcelona. Facultat de Farmàcia) ; Esteban, Gerard (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Viayna, Elisabet (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Szałaj, Natalia (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Vázquez, Javier (Universitat de Barcelona. Facultat de Farmàcia) ; Juárez-Jiménez, Jordi (Universitat de Barcelona. Facultat de Farmàcia) ; Sola, Irene (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Pérez, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Solé Piñol, Montserrat (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Luque Garriga, F. Xavier (Universitat de Barcelona. Facultat de Farmàcia) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Different azides and alkynes have been coupled via Cu-catalyzed 1,3-dipolar Huisgen cycloaddition to afford a novel family of N1- and C5-substituted 1,2,3-triazole derivatives that feature the propargylamine group typical of irreversible MAO-B inhibitors at the C4-side chain of the triazole ring. [...]
2016 - 10.1016/j.bmc.2016.06.045
Bioorganic & medicinal chemistry, Vol. 24 Núm. 20 (October 2016) , p. 4835-4854  
Detailed record - Creative Commons
4.
36 p, 1.6 MB New rhenium complexes with ciprofloxacin as useful models for understanding the properties of [99mTc]-ciprofloxacin radiopharmaceutical / Lecina Vicente, Joan (Universitat Autònoma de Barcelona. Departament de Química) ; Cortés Garmendia, M. Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Llagostera Casas, Montserrat (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Piera, Carlos (Hospital Clínic i Provincial de Barcelona) ; Suades Ortuño, Joan (Universitat Autònoma de Barcelona. Departament de Química)
Rhenium complexes with the antibiotic ciprofloxacin have been prepared to be studied as models of technetium radiopharmaceuticals. With this aim, the new rhenium complexes 1 {[ReO(Cpf)2]Cl}, 2 {[ReO(CpfH)2]Cl3} and 3 {fac-[Re(CO)3(H2O)(Cpf)]} with ciprofloxacin (CpfH=ciprofloxacin; Cpf=conjugated base of ciprofloxacin) have been synthesised and characterised by elemental analyses, IR, NMR ((1)H, (19)F and (13)C CP-MAS) spectroscopy, as well as MS measurements. [...]
2014 - 10.1016/j.bmc.2014.04.058
Bioorganic & medicinal chemistry, Vol. 22, Issue 13 (July 2014) , p. 3262-3269  
Detailed record -

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.
UAB Digital Repository of Documents :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.6
Maintained by ddd.bib@uab.cat  :: Metadata license:
Working with