UAB Digital Repository of Documents 4 records found  Search took 0.01 seconds. 
1.
25 p, 24.0 MB AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer / Muñoz-Lorente, Miguel A. (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO)) ; Martínez, Paula (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO)) ; Tejera, Águeda (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO)) ; Whittemore, Kurt (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO)) ; Moisés-Silva, Ana Carolina (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO)) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Blasco, María A. (Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre (CNIO))
Short and dysfunctional telomeres are sufficient to induce a persistent DNA damage response at chromosome ends, which leads to the induction of senescence and/or apoptosis and to various age-related conditions, including a group of diseases known as "telomere syndromes", which are provoked by extremely short telomeres owing to germline mutations in telomere genes. [...]
2018 - 10.1371/journal.pgen.1007562
PLoS Genetics, Vol. 14 (august 2018)  
2.
14 p, 5.0 MB Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis / González-García, Mary Paz (Centre de Recerca en Agrigenòmica) ; Pavelescu, Irina (Centre de Recerca en Agrigenòmica) ; Canela, Andrés (Centro Nacional de Investigaciones Oncológicas. Grupo de Telómeros y Telomerasa) ; Sevillano, Xavier (Universitat Ramon Llull. Grup de Recerca en Tecnologies Mèdia) ; Leehy, Katherine A. (Texas A&M University. Department of Biochemistry and Biophysics) ; Nelson, Andrew D.L. (Texas A&M University. Department of Biochemistry and Biophysics) ; Ibañes, Marta (Universitat de Barcelona. Departament d'Estructura i Constituents de la Matèria) ; Shippen, Dorothy E. (Texas A&M University. Department of Biochemistry and Biophysics) ; Blasco, María A. (Centro Nacional de Investigaciones Oncológicas. Grupo de Telómeros y Telomerasa) ; Caño Delgado, Ana I. (Centre de Recerca en Agrigenòmica)
Telomeres are specialized nucleoprotein caps that protect chromosome ends assuring cell division. Single-cell telomere quantification in animals established a critical role for telomerase in stem cells, yet, in plants, telomere-length quantification has been reported only at the organ level. [...]
2015 - 10.1016/j.celrep.2015.04.013
Cell reports, Vol. 11, issue 6 (May 2015) , p. 977-989  
3.
24 p, 5.3 MB Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres / Povedano, Juan Manuel ; Martinez, Paula ; Serrano, Rosa ; Tejera, Águeda ; Gómez-López, Gonzalo ; Bobadilla, Maria ; Flores, Juana Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Bosch, Fátima ; Blasco, María A
Pulmonary fibrosis is a fatal lung disease characterized by fibrotic foci and inflammatory infiltrates. Short telomeres can impair tissue regeneration and are found both in hereditary and sporadic cases. [...]
2018 - 10.7554/eLife.31299
eLife, Vol. 7 (january 2018)  
4.
16 p, 2.7 MB Gene therapy with the 1 telomere gene rescues decreased 1 levels with aging and prolongs mouse health span / Derevyanko, Aksinya (Spanish National Cancer Centre (CNIO)) ; Whittemore, Kurt (Spanish National Cancer Centre (CNIO)) ; Schneider, Ralph P. (Spanish National Cancer Centre (CNIO)) ; Jiménez, Verónica (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Bosch, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Blasco, María A. (Spanish National Cancer Centre (CNIO))
The shelterin complex protects telomeres by preventing them from being degraded and recognized as double-strand breaks. 1 is an essential component of shelterin, with important roles in telomere protection and telomere replication. [...]
2017 - 10.1111/acel.12677
Aging Cell, Vol. 16 (september 2017) , p. 1353-1368  

See also: similar author names
1 BLASCO, Mònica
5 Blasco, Maria A.
1 Blasco, Maria Pilar
1 Blasco, Mariví
1 Blasco, María
1 Blasco, María A
5 Blasco, María A.
1 Blasco, Mònica
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