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1.
20 p, 932.4 KB Drug-Drug Interactions with Antiretroviral Drugs in Pregnant Women Living with HIV : Are They Different from Non-Pregnant Individuals? / Bukkems, Vera E. (Radboud University Medical Center and Radboud Institute for Health Sciences (RIHS). Department of Pharmacy) ; Colbers, Angela (Radboud University Medical Center and Radboud Institute for Health Sciences (RIHS). Department of Pharmacy) ; Marzolini, Catia (University of Liverpool. Department of Molecular and Clinical Pharmacology) ; Molto, Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Burger, David M. (Radboud University Medical Center and Radboud Institute for Health Sciences (RIHS). Department of Pharmacy) ; Universitat Autònoma de Barcelona
Although the separate effects of drug-drug interactions and pregnancy on antiretroviral drug pharmacokinetics have been widely studied and described, their combined effect is largely unknown. Physiological changes during pregnancy may change the extent or clinical relevance of a drug-drug interaction in a pregnant woman. [...]
2020 - 10.1007/s40262-020-00914-x
Clinical Pharmacokinetics, Vol. 59 (july 2020) , p. 1217-1236  
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26 p, 1.1 MB A mixed finite element method for nonlinear diffusion equations / Burger, Martin (Institut für Numerische und Angewandte Mathematik (Munster, Alemanya)) ; Carrillo de la Plata, José Antonio (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Wolfram, Marie-Therese (University of Cambridge. Department of Applied Mathematics and Theoretical Physics) ; Universitat Autònoma de Barcelona. Centre de Recerca Matemàtica
We propose a mixed finite element method for a class of nonlinear diffusion equations, which is based on their interpretation as gradient flows in optimal transportation metrics. We introduce an appropriate linearization of the optimal transport problem, which leads to a mixed symmetric formulation. [...]
Centre de Recerca Matemàtica 2009 (Prepublicacions del Centre de Recerca Matemàtica ; 891)  

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1 Burger, Martin
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