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16 p, 4.7 MB |
BCL3 rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases
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Carbo-Meix, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Guijarro, Francesca (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Wang, Luojun (Hospital Clínic i Provincial de Barcelona) ;
Grau, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Royo, Romina (Barcelona Supercomputing Center) ;
Frigola, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Playa-Albinyana, Heribert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Buhler, Marco M. (University Hospital Zurich (Suïssa)) ;
Clot, Guillem (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Duran-Ferrer, Marti (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lu, Junyan (European Molecular Biology Laboratory, Heidelberg) ;
Granada, Isabel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Navarro, Jose Tomas (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bandiera, Laura (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
De Canal, Gabriella (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
Bonoldi, Emanuela (Anatomia Istologia Patologica e Citogenetica. Dipartimento Ematologia. Oncologia e Medicina Molecolare. Niguarda Cancer Center, Milano) ;
Climent, Fina (Institut d'Investigació Biomèdica de Bellvitge) ;
Ribera-Cortada, Inmaculada (Hospital Nostra Senyora de Meritxell. Escaldes-Engordany. Principat d'Andorra) ;
Fernandez-Caballero, Mariana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
De la Banda, Esmeralda (Institut d'Investigació Biomèdica de Bellvitge) ;
Do Nascimento, Janilson (Hospital Joan XXIII, Institut Català d'Oncologia, Tarragona) ;
Pineda, Alberto (Fundació Hospital de l'Esperit Sant) ;
Vela, Dolors (Hematologia Clínica. Hospital General de Granollers) ;
Rozman, Maria (Hospital Clínic i Provincial de Barcelona) ;
Aymerich, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Syrykh, Charlotte (Cancer Institute University of Toulouse-Oncopole, France) ;
Brousset, Pierre (Cancer Institute University of Toulouse-Oncopole, France) ;
Perera, Miguel (Hospital Dr Negrín, Las Palmas de Gran Canaria) ;
Yanez, Lucrecia (Hematology Department. Hospital Universitario Marqués de Valdecilla-Instituto de Investigación Valdecilla) ;
Ortin, Jesus Xavier (Hematology Department. Hospital Verge de la Cinta) ;
Tuset, Esperanza (Institut d'Investigació Biomèdica de Girona) ;
Zenz, Thorsten (University Hospital and University of Zürich) ;
Cook, James R. (Pathology and Laboratory Medicine Institute. Cleveland Clinic) ;
Swerdlow, Steven H. (University of Pittsburgh School of Medicine) ;
Martin-Subero, Jose I. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Colomer, Dolors (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Bea, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Costa, Dolors (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Nadeu, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Campo, Elias (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The t(14;19)(q32;q13) often juxtaposes BCL3 with immunoglobulin heavy chain (IGH) resulting in overexpression of the gene. In contrast to other oncogenic translocations, BCL3 rearrangement (BCL3-R) has been associated with a broad spectrum of lymphoid neoplasms. [...]
2024 -  10.3324/haematol.2023.283209
Haematologica, Vol. 109 Núm. 2 (february 2024) , p. 493-508
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2.
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16 p, 3.8 MB |
Genetic and phenotypic attributes of splenic marginal zone lymphoma
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Bonfiglio, Ferdinando (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bruscaggin, Alessio (Institute of Oncology Research, Bellinzona, Switzerland) ;
Guidetti, Francesca (Institute of Oncology Research, Bellinzona, Switzerland) ;
Terzi di Bergamo, Lodovico (Institute of Oncology Research, Bellinzona, Switzerland) ;
Faderl, Martin (Institute of Oncology Research, Bellinzona, Switzerland) ;
Spina, Valeria (Institute of Oncology Research, Bellinzona, Switzerland) ;
Condoluci, Adalgisa (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bonomini, Luisella (International Extranodal Lymphoma Study Group, Bellinzona, Switzerland) ;
Forestieri, Gabriela (Institute of Oncology Research, Bellinzona, Switzerland) ;
Koch, Ricardo (Institute of Oncology Research, Bellinzona, Switzerland) ;
Piffaretti, Deborah (Institute of Oncology Research, Bellinzona, Switzerland) ;
Pini, Katia (Institute of Oncology Research, Bellinzona, Switzerland) ;
Pirosa, Maria Cristina (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Cittone, Micol Giulia (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Arribas, Alberto (Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland) ;
Lucioni, Marco (Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Pavia, Italy) ;
Ghilardi, Guido (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.) ;
Wu, Wei (Institute of Oncology Research, Bellinzona, Switzerland) ;
Arcaini, Luca (University of Pavia, Pavia, Italy.) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bastidas-Mora, Gabriela (Hospital Clínic i Provincial de Barcelona) ;
Bea, Sílvia (Hospital Clínic i Provincial de Barcelona) ;
Boldorini, Renzo (University of Eastern Piedmont, Novara, Italy) ;
Broccoli, Alessandro (IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy.) ;
Buehler, Marco Matteo (University Hospital Zurich, Switzerland) ;
Canzonieri, Vincenzo (Pathology Unit, CRO Aviano National Cancer Institute, Aviano, Italy) ;
Cascione, Luciano (Institute of Oncology Research, Bellinzona, Switzerland) ;
Ceriani, Luca (Clinic of Nuclear Medicine and PET-CT Centre, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Cogliatti, Sergio (Institute of Pathology, Kantonsspital St Gallen, St Gallen, Switzerland) ;
Corradini, Paolo (Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy) ;
Derenzini, Enrico (European Institute of Oncology (IEO) IRCCS, Milan, Italy) ;
Devizzi, Liliana (Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Italy) ;
Dietrich, Sascha (University Hospital Heidelberg, Germany) ;
Elia, Angela Rita (Institute of Oncology Research, Bellinzona, Switzerland) ;
Facchetti, Fabio (Pathology Unit, Spedali Civili, Brescia, Italy) ;
Gaidano, Gianluca (University of Eastern Piedmont, Novara, Italy) ;
Garcia, Juan Fernando (MD Anderson Cancer Center, Madrid) ;
Gerber, Bernhard (Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Ghia, Paolo (IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy) ;
Gomes da Silva, Maria (Instituto Português de Oncologia de Lisboa, Portugal) ;
Gritti, Giuseppe (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy) ;
Guidetti, Anna (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Italy) ;
Hitz, Felicitas (Kantonsspital St Gallen, St Gallen, Switzerland) ;
Inghirami, Giorgio (Weill Cornell Medical College, New York) ;
Ladetto, Marco (Azienda Ospedaliera SS Antonio e Biagio, Alessandria, Italy) ;
Lopez-Guillermo, Armando (Hospital Clínic i Provincial de Barcelona) ;
Lucchini, Elisa (Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy) ;
Maiorana, Antonino (Universitá degli Studi di Modena e Reggio Emilia, Modena, Italy) ;
Marasca, Roberto (University of Modena and Reggio Emilia, Modena, Italy) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Meignin, Veronique (Saint Louis Hospital, Paris, France) ;
Merli, Michele (University of Insubria and ASST Sette Laghi, Ospedale di Circolo of Varese, Varese, Italy) ;
Moccia, Alden (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Mollejo, Manuela (Hospital Virgen de la Salud (Toledo)) ;
Montalban, Carlos (MD Anderson Cancer Center, Madrid) ;
Novak, Urban (University of Bern, Bern, Switzerland) ;
Oscier, David Graham (University Hospitals Dorset, Bournemouth, United Kingdom) ;
Passamonti, Francesco (University of Insubria) ;
Piazza, Francesco (Ospedale Universitario di Padova, Italy) ;
Pizzolitto, Stefano (General Hospital S Maria della Misericordia, Udine, Italy) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy) ;
Sabattini, Elena (University of Bologna, Italy) ;
Salles, Gilles (Université de Lyon, France) ;
Santambrogio, Elisa (Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy) ;
Scarfò, Lydia (IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy) ;
Stathis, Anastasios (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Stüssi, Georg (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Geyer, Julia T. (Weill Cornell Medical College, New York) ;
Tapia, G. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tarella, Corrado (European Institute of Oncology (IEO) IRCCS, Milan, Italy) ;
Thieblemont, Catherine (Université de Paris, France) ;
Tousseyn, Thomas (University Hospitals Leuven, Belgium) ;
Tucci, Alessandra (Spedali Civili, Brescia, Italy.) ;
Vanini, Giorgio (University of Bern, Switzerland) ;
Visco, Carlo (University of Verona, Italy) ;
Vitolo, Umberto (Candiolo Cancer Institute (FPO-IRCCS), Candiolo, Turin, Italy) ;
Walewska, Renata (University Hospitals Dorset, Bournemouth, United Kingdom) ;
Zaja, Francesco (Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy) ;
Zenz, Thorsten (University Hospital Zurich, Switzerland) ;
Zinzani, Pier Luigi (Università di Bologna, Italy) ;
Khiabanian, Hossein (Rutgers University, New Brunswick) ;
Calcinotto, Arianna (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bertoni, Francesco (Institute of Oncology Research, Bellinzona, Switzerland) ;
Bhagat, Govind (Columbia University, New York, USA) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
de Leval, Laurence (Institut Universitaire de Pathologie, Lausanne, Switzerland) ;
Dirnhofer, Stefan (University Hospital Basel (Basilea, Suïssa)) ;
Pileri, Stefano A. (European Institute of Oncology IRCCS, Milan, Italy) ;
Piris, Miguel Angel (Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Madrid) ;
Traverse-Glehen, Alexandra (Centre Hospitalier Lyon Sud, Lyon, France) ;
Tzankov, Alexander (University Hospital Basel (Basilea, Suïssa)) ;
Paulli, Marco (Fondazione IRCCS Policlinico San Matteo and Università degli Studi di Pavia, Italy) ;
Ponzoni, Maurilio (Ateneo Vita-Salute San Raffaele University and Pathology Unit San Raffaele Scientific Institute, Milan, Italy) ;
Mazzucchelli, Luca (antonal Institute of Pathology, Locarno, Switzerland) ;
Cavalli, Franco (Institute of Oncology Research, Bellinzona, Switzerland; and.) ;
Zucca, Emanuele (International Extranodal Lymphoma Study Group, Bellinzona, Switzerland) ;
Rossi, Davide (Oncology Institute of Southern Switzerland, Bellinzona, Switzerland) ;
Universitat Autònoma de Barcelona
Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity. The clinical course is variable, multiple genes are mutated with no unifying mechanism, and essential regulatory pathways and surrounding microenvironments are diverse. [...]
2022 - 10.1182/blood.2021012386
Blood, Vol. 139 Núm. 5 (february 2022) , p. 732-747
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15 p, 3.6 MB |
Unraveling the genetics of transformed splenic marginal zone lymphoma
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Grau, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
López, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Navarro, Alba (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Frigola, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Nadeu, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Clot, Guillem (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bastidas-Mora, Gabriela (Hospital Clínic i Provincial de Barcelona) ;
Alcoceba, Miguel (Hospital Universitario de Salamanca) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Blanes, Margarita (Hospital General Universitario de Elda) ;
Colomer, Dolors (Hospital Clínic i Provincial de Barcelona) ;
Costa, Dolors (Hospital Clínic i Provincial de Barcelona) ;
Domingo-Domenech, Eva (Institut d'Investigació Biomèdica de Bellvitge) ;
Enjuanes, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Escoda, Lourdes (Hospital Universitari Joan XXIII de Tarragona) ;
Forcada, Pilar (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Giné, Eva (Hospital Clínic i Provincial de Barcelona) ;
Lopez-Guerra, Mónica (Hospital Clínic i Provincial de Barcelona) ;
Ramón, Olga (Hospital General de Igualada) ;
Rivas-Delgado, Alfredo (Hospital Clínic i Provincial de Barcelona) ;
Folch, Laura Vicente (Consorci Sanitari de Terrassa) ;
Wotherspoon, Andrew (Royal Marsden NHS Foundation Trust, United Kingdom) ;
Climent, Fina (Institut d'Investigació Biomèdica de Bellvitge) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
López-Guillermo, Armando (Hospital Clínic i Provincial de Barcelona) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Bea, Sílvia (Hospital Clínic i Provincial de Barcelona)
The genetic mechanisms associated with splenic marginal zone lymphoma (SMZL) transformation are not well defined. We studied 41 patients with SMZL that eventually underwent large B-cell lymphoma transformation. [...]
2023 - 10.1182/bloodadvances.2022009415
Blood advances, Vol. 7 Núm. 14 (july 2023) , p. 3695-3709
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11 p, 2.0 MB |
Development of a Novel Anti-CD19 Chimeric Antigen Receptor : A Paradigm for an Affordable CAR T Cell Production at Academic Institutions
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Castellà, Maria (Hospital Clínic i Provincial de Barcelona) ;
Boronat, Anna (Hospital Clínic i Provincial de Barcelona) ;
Martín-Ibáñez, Raquel (Universitat de Barcelona) ;
Rodríguez, Vanina (Institut d'Investigacions Biomèdiques August Pi i Sunyer - IDIBAPS) ;
Suñé, Guillermo (Hospital Clínic i Provincial de Barcelona) ;
Caballero, Miguel (Hospital Clínic i Provincial de Barcelona) ;
Marzal, Berta (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Amill, Lorena (Hospital Clínic i Provincial de Barcelona) ;
Martín-Antonio, B. (Hospital Clínic i Provincial de Barcelona) ;
Castaño Cardoso, Julio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Balagué, Olga (Hospital Clínic i Provincial de Barcelona) ;
González-Navarro, Europa Azucena (Hospital Clínic i Provincial de Barcelona) ;
Serra-Pages, Carles (Hospital Clínic i Provincial de Barcelona) ;
Engel, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Vilella, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Benítez Ribas, Daniel (Hospital Clínic i Provincial de Barcelona) ;
Ortiz-Maldonado, Valentín (Hospital Clínic i Provincial de Barcelona) ;
Cid, Joan (Hospital Clínic i Provincial de Barcelona) ;
Tabera, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Canals, Josep M. (Universitat de Barcelona) ;
Lozano, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Baumann, Tycho (Hospital Clínic i Provincial de Barcelona) ;
Vilarrodona, Anna (Institut d'Investigació Biomèdica Sant Pau) ;
Trias, Esteve (Hospital Clínic i Provincial de Barcelona) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Urbano-Ispizua, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Yagüe, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Galán, Patricia (Centro de Investigación Biomédica en Red de Cáncer) ;
Rives, Susana (Institut de Recerca Sant Joan de Déu) ;
Delgado, Julio (Hospital Clínic i Provincial de Barcelona) ;
Juan, Manel (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Genetically modifying autologous T cells to express an anti-CD19 chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19+ B cell malignancies in several clinical trials (CTs). [...]
2019 - 10.1016/j.omtm.2018.11.010
Molecular Therapy. Methods & Clinical Development, Vol. 12 (15 2019) , p. 134-144
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18 p, 2.5 MB |
The EHA Research Roadmap : Malignant Lymphoid Diseases
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Dreyling, Martin (LMU Hospital (Alemanya)) ;
André, Marc (Université Catholique de Louvain (bèlgica)) ;
Gökbuget, Nicola (Goethe University (Alemanya)) ;
Tilly, Hervé (Centre Henri Becquerel and Université de Rouen (França)) ;
Jerkeman, Mats (Skåne University and Lund University (Suècia)) ;
Gribben, John (Queen Mary University of London (Regne Unit)) ;
Ferreri, Andrés (IRCCS San Raffaele Scientific Institute (Itàlia)) ;
Morel, Pierre (CHU Amiens Picardie (França)) ;
Stilgenbauer, Stephan (Universität Ulm (Alemanya)) ;
Fox, Christopher (University of Nottingham (Regne Unit)) ;
Maria Ribera, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zweegman, Sonja (Amsterdam UMC (Països Baixos)) ;
Aurer, Igor (University of Zagreb (Zagreb)) ;
Bödör, Csaba (Semmelweis University (Hongria)) ;
Burkhardt, Birgit (Pädiatrische Hämatologie und Onkologie (Alemanya)) ;
Buske, Christian (University Hospital of Ulm (Alemanya)) ;
Dollores Caballero, Maria (El Instituto de Investigación Biomédica de Salamanca (Salamanca, Espanya)) ;
Campo, Elias (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Chapuy, Bjoern (Berlin Institute of Health (Alemanya)) ;
Davies, Andrew (University of Southampton (Regne Unit)) ;
de Leval, Laurence (Lausanne University Switzerland (Suïssa)) ;
Doorduijn, Jeanette (University Medical Center Rotterdam the Netherlands (Països Baixos)) ;
Federico, Massimo (GVM Care & Research (Itàlia)) ;
Gaulard, Philippe (Hôpital Henri Mondor (França)) ;
Gay, Francesca (AOU Città Della Salute e Della Scienza (Itàlia)) ;
Ghia, Paolo (IRCCS Ospedale San Raffaele (Itàlia)) ;
Grønbæk, Kirsten (University of Copenhagen (Dinamarca)) ;
Goldschmidt, Hartmut (University Hospital Heidelberg (Alemanya)) ;
Kersten, Marie-Jose (Cancer Center Amsterdam and LYMMCARE the Netherlands (Països Baixos)) ;
Kiesewetter, Barbara (Medical University of Vienna (Àustria)) ;
Landman-Parker, Judith (Sorbonne Université APHP/hôpital A Trousseau (França)) ;
Le Gouill, Steven (Clinique du Centre Hospitalier Universitaire (CHU) de Nantes (França)) ;
Lenz, Georg (Medical University Hospital Münster (Alemanya)) ;
Leppä, Sirpa (Helsinki University Hospital Comprehensive Cancer Centre Finland (Finlandia)) ;
López Guillermo, Armando (Hospital Clínic i Provincial de Barcelona) ;
Macintyre, Elizabeth (Assistance Publique-Hôpitaux de Paris (França)) ;
Mantega, Maria Victoria Mateos (Universidad de Salamanca (Salamanca, Espanya)) ;
Moreau, Philippe (University Hospital Hotel-Dieu (França)) ;
Moreno, Carol (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Nadel, Bertrand (Aix Marseille Univ (França)) ;
Okosun, Jessica (Queen Mary University of London (Regne Unit)) ;
Owen, Roger (St James's Institute of Oncology (Regne Unit)) ;
Pospisilova, Sarka (University Hospital Brno (Txèquia)) ;
Pott, Christiane (Universitätsklinikum Schleswig-Holstein (Alemanya)) ;
Robak, Tadeusz (Medical University of Lodz (Polònia)) ;
Spina, Michelle (National Cancer Institute (Itàlia)) ;
Stamatopoulos, Kostas (Centre for Research and Technology Hellas Greece (Grècia)) ;
Stary, Jan (Charles University Prague University Hospital Czech Republic (Txèquia)) ;
Tarte, Karin (Immunology and Cell Therapy Lab at Rennes University Hospital (França)) ;
Tedeschi, Allessandra (Niguarda Hospital Milano (Itàlia)) ;
Thieblemont, Catherine (Assistance Publique-Hôpitaux de Paris (França)) ;
Trappe, Ralf Ulrich (DIAKO Hospital Bremen (Alemanya)) ;
Trümper, Lorenz H. (University Medicine Goettingen (Alemanya)) ;
Salles, Gilles (Weill Cornell Medicine (Estats Units)) ;
Universitat Autònoma de Barcelona
2022 - 10.1097/HS9.0000000000000726
HemaSphere, Vol. 6 (may 2022)
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1 p, 825.9 KB |
Correction : Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
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Mansouri, Larry (Karolinska Institutet (Estocolm, Suècia)) ;
Thorvaldsdottir, Birna (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ;
Sutton, Lesley-Ann (Karolinska Institutet (Estocolm, Suècia)) ;
Karakatsoulis, Georgios (University of Ioannina) ;
Meggendorfer, Manja (MLL Munich Leukemia Laboratory) ;
Parker, Helen (University of Southampton) ;
Nadeu, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Brieghel, Christian (Copenhagen University Hospital) ;
Laidou, Stamatia (Institute of Applied Biosciences) ;
Moia, Riccardo (Università del Piemonte Orientale) ;
Rossi, Davide (Institute of Oncology Research) ;
Catherwood, Mark (Queen's University Belfast) ;
Kotaskova, Jana (Masaryk University) ;
Delgado, Julio (Hospital Clínic i Provincial de Barcelona) ;
Rodríguez-Vicente, Ana E. (Universidad de Salamanca) ;
Benito, Rocío (Universidad de Salamanca) ;
Rigolin, Gian Matteo (University of Ferrara) ;
Bonfiglio, Silvia (Università Vita Salute San Raffaele) ;
Scarfo, Lydia (Università Vita Salute San Raffaele) ;
Mattsson, Mattias (Uppsala University) ;
Davis, Zadie (University Hospitals Dorset) ;
Gogia, Ajay (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Rani, Lata (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Baliakas, Panagiotis (Uppsala University) ;
Foroughi-Asl, Hassan (Karolinska Institutet (Estocolm, Suècia)) ;
Jylhä, Cecilia (Karolinska Institutet (Estocolm, Suècia)) ;
Skaftason, Aron (Karolinska Institutet (Estocolm, Suècia)) ;
Rapado, Inmaculada (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
Miras, Fatima (Hospital Universitario 12 de Octubre (Madrid)) ;
Martinez-Lopez, Joaquín (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
de la Serna, Javier (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
Rivas, Jesús María Hernández (Universidad de Salamanca) ;
Thornton, Patrick (Beaumont Hospital (Dublín, Irlanda)) ;
Larráyoz, María José (Universidad de Navarra) ;
Calasanz, M.J (Universidad de Navarra) ;
Fésüs, Viktória (Semmelweis University) ;
Mátrai, Zoltán (Central Hospital of Southern Pest-National Institute of Hematology and Infectious Diseases (Budapest, Hongria)) ;
Bödör, Csaba (Semmelweis University) ;
Smedby, Karin E. (Karolinska Institutet (Estocolm, Suècia)) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gupta, Ritu (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Bullinger, Lars (Charité - Universitätsmedizin Berlin) ;
Bosch José, Francesc Xavier 1947- (Vall d'Hebron Institut d'Oncologia) ;
Tazón-Vega, Bárbara (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Baran-Marszak, Fanny (Hôpital Avicenne AP-HP) ;
Oscier, David (University Hospitals Dorset) ;
Nguyen-Khac, Florence (Sorbonne University) ;
Zenz, Thorsten (University Hospital of Zurich) ;
Terol, Maria Jose (Universitat de València) ;
Cuneo, Antonio (University of Ferrara) ;
Hernández-Sánchez, María (Universidad de Salamanca) ;
Pospisilova, Sarka (Masaryk University) ;
Mills, Ken (Queen's University Belfast) ;
Gaidano, Gianluca (Università del Piemonte Orientale) ;
Niemann, Carsten U. (Copenhagen University Hospital) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
Strefford, Jonathan C. (University of Southampton) ;
Ghia, Paolo (Università Vita Salute San Raffaele) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences) ;
Rosenquist, Richard (Karolinska University Hospital and Karolinska Institutet (Suècia))
2023 - 10.1038/s41375-023-01813-3
Leukemia, Vol. 37 (january 2023) , p. 504
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7.
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9 p, 1.7 MB |
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status : a study by ERIC in HARMONY
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Mansouri, Larry (Karolinska Institutet (Estocolm, Suècia)) ;
Thorvaldsdottir, Birna (Karolinska Institutet (Estocolm, Suècia)) ;
Sutton, Lesley-Ann (Karolinska Institutet (Estocolm, Suècia)) ;
Karakatsoulis, Georgios (University of Ioannina. Department of Mathematics) ;
Meggendorfer, Manja (MLL Munich Leukemia Laboratory) ;
Parker, Helen (University of Southampton) ;
Nadeu, Ferran (Centro de Investigación Biomédica en Red de Cáncer) ;
Brieghel, Christian (Copenhagen University Hospital. Department of Hematology, Rigshospitalet) ;
Laidou, Stamatia (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ;
Moia, Riccardo (Università del Piemonte Orientale) ;
Rossi, Davide (Institute of Oncology Research (Suïssa)) ;
Catherwood, Mark (Queen's University Belfast) ;
Kotaskova, Jana (Masaryk University) ;
Delgado, Julio (Universitat de Barcelona) ;
Rodríguez-Vicente, Ana E. (Hospital Universitario de Salamanca) ;
Benito, Rocío (Hospital Universitario de Salamanca) ;
Rigolin, Gian Matteo (University of Ferrara) ;
Bonfiglio, Silvia (Università Vita Salute San Raffaele and IRCCS Ospedale San Raffaele) ;
Scarfo, Lydia (Università Vita Salute San Raffaele) ;
Mattsson, Mattias (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Davis, Zadie (Molecular Pathology Department, University Hospitals Dorset) ;
Gogia, Ajay (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Rani, Lata (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Baliakas, Panagiotis (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Foroughi-Asl, Hassan (Karolinska Institutet (Estocolm, Suècia)) ;
Jylhä, Cecilia (Karolinska Institutet (Estocolm, Suècia)) ;
Skaftason, Aron (Karolinska Institutet (Estocolm, Suècia)) ;
Rapado, Inmaculada (Spanish National Cancer Research) ;
Miras, Fatima (Hospital Universitario 12 de Octubre (Madrid)) ;
Martinez-Lopez, Joaquín (Spanish National Cancer Research) ;
de la Serna, Javier (Spanish National Cancer Research) ;
Rivas, Jesús María Hernández (Hospital Universitario de Salamanca) ;
Thornton, Patrick (Beaumont Hospital. Haematology Department) ;
Larráyoz, María José (Instituto de Investigación Sanitaria de Navarra) ;
Calasanz, M.J (Instituto de Investigación Sanitaria de Navarra) ;
Fésüs, Viktória (Semmelweis University) ;
Mátrai, Zoltán (Central Hospital of Southern Pest-National Institute of Hematology and Infectious Diseases, Budapest, Hungary) ;
Bödör, Csaba (Semmelweis University) ;
Smedby, Karin E. (Karolinska Institutet (Suècia). Department of Medicine Solna) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gupta, Ritu (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Bullinger, Lars (Charité - Universitätsmedizin Berlin) ;
Bosch José, Francesc Xavier 1947- (Vall d'Hebron Institut d'Oncologia) ;
Tazón-Vega, Bárbara (Vall d'Hebron Institut d'Oncologia) ;
Baran-Marszak, Fanny (Service d'hématologie Biologique Hôpital Avicenne Assistance Publique des Hôpitaux de Paris) ;
Oscier, David (University Hospitals Dorset) ;
Nguyen-Khac, Florence (Sorbonne University) ;
Zenz, Thorsten (University Hospital and University of Zurich. Department of Oncology and Haematology) ;
Terol, Maria Jose (University of Valencia. Department of Hematology) ;
Cuneo, Antonio (University of Ferrara. Hematology-Department of Medical Sciences) ;
Hernández-Sánchez, María (Hospital Universitario de Salamanca) ;
Pospisilova, Sarka (Masaryk University. Central European Institute of Technology) ;
Mills, Ken (Queen's University Belfast) ;
Gaidano, Gianluca (Università del Piemonte Orientale) ;
Niemann, Carsten U. (Copenhagen University Hospital) ;
Campo, Elias (Universitat de Barcelona) ;
Strefford, Jonathan C. (University of Southampton) ;
Ghia, Paolo (Università Vita Salute San Raffaele and IRCCS Ospedale San Raffaele) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences (Grècia)) ;
Rosenquist, Richard (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Universitat Autònoma de Barcelona
Recent evidence suggests that the prognostic impact of gene mutations in patients with chronic lymphocytic leukemia (CLL) may differ depending on the immunoglobulin heavy variable (IGHV) gene somatic hypermutation (SHM) status. [...]
2022 - 10.1038/s41375-022-01802-y
Leukemia, Vol. 37 (december 2022) , p. 339-347
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8.
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12 p, 546.9 KB |
Consumption of ultra-processed food and drinks and chronic lymphocytic leukemia in the mcc-spain study
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Solans, Marta (Universitat de Girona) ;
Fernández-Barrés, Sílvia (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Romaguera, Dora (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Benavente, Yolanda (Institut Català d'Oncologia) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gracia-Lavedan, Esther (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Costas, Laura (Institut Català d'Oncologia) ;
Robles, Claudia (Institut Català d'Oncologia) ;
Gonzalez-Barca, Eva (Institut d'Investigació Biomèdica de Bellvitge) ;
Banda, Esmeralda de la (Institut d'Investigació Biomèdica de Bellvitge) ;
Alonso, Esther (Institut d'Investigació Biomèdica de Bellvitge) ;
Aymerich, Marta (Institut Clínic de Nefrologia i Urologia) ;
Campo, Elias (Institut Clínic de Nefrologia i Urologia) ;
Llorca, Javier (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Fernández-Tardon, Guillermo (Instituto de Investigación Sanitaria del Principado de Asturias) ;
Olmedo-Requena, Rocío (Instituto de Investigación Sanitaria de Granada) ;
Gimeno, Eva (Hospital del Mar (Barcelona, Catalunya)) ;
Castaño-Vinyals, Gemma (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Aragonés, Nuria (Epidemiology Section. Public Health Division. Department of Health (Madrid)) ;
Kogevinas, M (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Pollán, Marina (Instituto de Salud Carlos III) ;
Sanjose, Sílvia de (Sexual and Reproductive Health. PATH (Estats Units d'Amèrica)) ;
Amiano, Pilar (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Casabonne, Delphine (Institut Català d'Oncologia) ;
Universitat Autònoma de Barcelona
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in Western countries. Its etiology is largely unknown but increasing incidence rates observed worldwide suggest that lifestyle and environmental factors such as diet might play a role in the development of CLL. [...]
2021 - 10.3390/ijerph18105457
International journal of environmental research and public health, Vol. 18 Núm. 10 (february 2021) , p. 5457
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9.
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7 p, 5.6 MB |
Results of ARI-0001 CART19 Cells in Patients With Chronic Lymphocytic Leukemia and Richter's Transformation
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Ortiz-Maldonado, Valentín (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Frigola, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Español-Rego, Marta (Hospital Clínic i Provincial de Barcelona) ;
Balagué, Olga (Hospital Clínic i Provincial de Barcelona) ;
Martínez Cibrián, Núria (Hospital Clínic i Provincial de Barcelona) ;
Magnano, Laura (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Giné, Eva (Centro de Investigación Biomédica en Red de Cáncer) ;
Pascal, Mariona (Hospital Clínic i Provincial de Barcelona) ;
Correa, Juan G. (Hospital Clínic i Provincial de Barcelona) ;
Martínez-Roca, Alexandra (Hospital Clínic i Provincial de Barcelona) ;
Cid, Joan (Hospital Clínic i Provincial de Barcelona) ;
Lozano, Miquel (Universitat de Barcelona. Departament de Medicina) ;
Villamor, Neus (Hospital Clínic i Provincial de Barcelona) ;
Benítez Ribas, Daniel (Hospital Clínic i Provincial de Barcelona) ;
Esteve Reyner, Jordi (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
López Guillermo, Armando (Universitat de Barcelona. Departament de Medicina) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
Urbano Ispizua, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Juan, Manel (Universitat de Barcelona. Departament de Medicina) ;
Delgado, Julio (Universitat de Barcelona. Departament de Medicina)
CART19 cells are emerging as an alternative therapy for patients with chronic lymphocytic leukemia (CLL). Here we report the outcome of nine consecutive patients with CLL treated with ARI-0001 CART19 cells, six of them with Richter's transformation (RT). [...]
2022 - 10.3389/fonc.2022.828471
Frontiers in Oncology, Vol. 12 (31 2022) , p. 828471
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10.
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10 p, 4.1 MB |
Clinico-biological features and outcome of patients with splenic marginal zone lymphoma with histological transformation
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Bastidas-Mora, Gabriela (Hospital Clínic i Provincial de Barcelona) ;
Bea, Sílvia (Centro de Investigación Biomédica en Red de Cáncer) ;
Navarro, Alba (Centro de Investigación Biomédica en Red de Cáncer) ;
Gine, Eva (Centro de Investigación Biomédica en Red de Cáncer) ;
Costa, Dolors (Centro de Investigación Biomédica en Red de Cáncer) ;
Delgado, Julio (Centro de Investigación Biomédica en Red de Cáncer) ;
Baumann, Tycho (Hospital Universitario 12 de Octubre (Madrid)) ;
Magnano, Laura (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rivas-Delgado, Alfredo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Villamor, Neus (Centro de Investigación Biomédica en Red de Cáncer) ;
Colomer, Dolors (Centro de Investigación Biomédica en Red de Cáncer) ;
Lopez-Guerra, Mónica (Centro de Investigación Biomédica en Red de Cáncer) ;
Rozman, Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Balagué, Olga (Centro de Investigación Biomédica en Red de Cáncer) ;
Martínez, Daniel (Centro de Investigación Biomédica en Red de Cáncer) ;
Baptista, Maria Joao (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Escoda, Lourdes (Hospital Universitari Joan XXIII de Tarragona) ;
Alcoceba, Miguel (Hospital Universitario de Salamanca) ;
Blanes, Margarita (Hospital General Universitario de Elda) ;
Climent, Fina (Institut d'Investigació Biomèdica de Bellvitge) ;
Campo, Elias (Centro de Investigación Biomédica en Red de Cáncer) ;
Wotherspoon, Andrew (The Royal Marsden NHS Foundation Trust) ;
López Guillermo, Armando (Centro de Investigación Biomédica en Red de Cáncer) ;
Matutes, Estella (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
We describe 36 patients with splenic marginal zone lymphoma (SMZL) with transformation (SMZL-T), including 15 from a series of 84 patients with SMZL diagnosed at the Hospital Clinic of Barcelona (HCB) and 21 diagnosed with SMZL-T in other centres. [...]
2022 - 10.1111/bjh.17815
British Journal of Haematology, Vol. 196 Núm. 1 (january 2022) , p. 146-155
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