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11.
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9 p, 2.7 MB |
Genetic association study of childhood aggression across raters, instruments, and age
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Ip, Hill F. (Vrije Universiteit Amsterdam) ;
van der Laan, Camiel M. (Netherlands Institute for the Study of Crime and Law Enforcement) ;
Krapohl, Eva M. L. (King's College London) ;
Brikell, Isabell (Karolinska Institutet (Estocolm, Suècia)) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nolte, Ilja M. (University of Groningen) ;
Pourcain, Beate St (Radboud University) ;
Bolhuis, Koen (Erasmus University Medical Center) ;
Palviainen, Teemu (University of Helsinki) ;
Zafarmand, Hadi (University of Amsterdam) ;
Colodro-Conde, Lucía (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Gordon, Scott D (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Zayats, Tetyana (Stanley Center for Psychiatric Research) ;
Aliev, Fazil (Karabuk University) ;
Jiang, Chang (University of Florida) ;
Wang, Carol A. (The University of Newcastle) ;
Saunders, Gretchen (University of Minnesota) ;
Karhunen, Ville (Imperial College London) ;
Hammerschlag, Anke R. (Amsterdam Public Health Research Institute) ;
Adkins, Daniel E. (University of Utah) ;
Border, Richard (University of Colorado Boulder) ;
Peterson, Roseann E. (Virginia Commonwealth University) ;
Prinz, Joseph A. (Duke University) ;
Thiering, Elisabeth (Ludwig-Maximilians-University of Munich) ;
Seppälä, Ilkka (Tampere University) ;
Vilor-Tejedor, Natàlia (Fundació Pasqual Maragall (FPM)) ;
Ahluwalia, Tarunveer Singh (Steno Diabetes Center Copenhagen) ;
Day, Felix R. (University of Cambridge School of Clinical Medicine) ;
Hottenga, Jouke Jan (Vrije Universiteit Amsterdam) ;
Allegrini, Andrea G. (King's College London) ;
Rimfeld, Kaili (King's College London) ;
Chen, Qi (Karolinska Institutet (Estocolm, Suècia)) ;
Lu, Yi (Karolinska Institutet (Estocolm, Suècia)) ;
Martin, Joanna (Cardiff University) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Español-Martín, Gemma (Hospital Universitari Vall d'Hebron) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Neumann, Alexander (Jewish General Hospital) ;
Ensink, Judith (De Bascule, Academic Centre for Child and Adolescent Psychiatry) ;
Grasby, Katrina (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Morosoli, José J. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Tong, Xiaoran (University of Florida) ;
Marrington, Shelby (The University of Queensland) ;
Middeldorp, Christel (Children's Health Queensland Hospital) ;
Scott, James G. (Queensland Centre for Mental Health Research) ;
Vinkhuyzen, Anna (University of Queensland) ;
Shabalin, Andrey A. (University of Utah) ;
Corley, Robin (University of Colorado Boulder) ;
Evans, Luke M. (University of Colorado Boulder) ;
Sugden, Karen (Duke University) ;
Alemany, Sílvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Sass, Lærke (University of Copenhagen) ;
Vinding, Rebecca (University of Copenhagen) ;
Ruth, Kate (University of Exeter Medical School) ;
Tyrrell, Jess (University of Exeter Medical School) ;
Davies, Gareth E. (Avera Institute for Human Genetics) ;
Ehli, Erik A. (Avera Institute for Human Genetics) ;
Hagenbeek, Fiona A. (Vrije Universiteit Amsterdam) ;
De Zeeuw, Eveline (Vrije Universiteit Amsterdam) ;
Van Beijsterveldt, Toos C.E.M. (Vrije Universiteit Amsterdam) ;
Larsson, Henrik (Orebro University) ;
Snieder, Harold (University of Groningen) ;
Verhulst, Frank C. (Copenhagen University Hospital) ;
Amin, Najaf (Erasmus University Medical Center) ;
Whipp, Alyce M. (University of Helsinki) ;
Korhonen, Tellervo (University of Helsinki) ;
Vuoksimaa, Eero (University of Helsinki) ;
Rose, Richard J. (Indiana University) ;
Uitterlinden, André G. (Netherlands Genomics Initiative (NGI)) ;
Heath, Andrew C. (Washington University) ;
Madden, Pamela (Washington University) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Harris, Jennifer R. (The Norwegian Institute of Public Health) ;
Helgeland, Øyvind (The Norwegian Institute of Public Health) ;
Johansson, Stefan E (University of Bergen) ;
Knudsen, Gun Peggy S. (The Norwegian Institute of Public Health) ;
Njolstad, Pal Rasmus (University of Bergen) ;
Lu, Qing (University of Florida) ;
Rodriguez, Alina (University of Lincoln) ;
Henders, Anjali K. (University of Queensland) ;
Mamun, Abdullah (University of Queensland) ;
Najman, Jackob M. (The University of Queensland) ;
Brown, Sandy (University of California) ;
Hopfer, Christian (University of Colorado School of Medicine) ;
Krauter, Kenneth (University of Colorado Boulder) ;
Reynolds, Chandra (University of California Riverside) ;
Smolen, Andrew (University of Colorado Boulder) ;
Stallings, Michael (University of Colorado Boulder) ;
Wadsworth, Sally (University of Colorado Boulder) ;
Wall, Tamara L. (University of California) ;
Silberg, Judy L. (Virginia Commonwealth University) ;
Miller, Allison (University of Otago Christchurch) ;
Keltikangas-Järvinen, Liisa (University of Helsinki) ;
Hakulinen, Christian (University of Helsinki) ;
Pulkki-Råback, Laura (University of Helsinki) ;
Havdahl, Alexandra (Norwegian Institute of Public Health) ;
Magnus, Per (Norwegian Institute of Public Health) ;
Raitakari, Olli T. (Turku University Hospital) ;
Perry, John R. B. (University of Cambridge School of Clinical Medicine) ;
Llop, Sabrina (Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Lopez-Espinosa, Maria-Jose (Universitat de València) ;
Bønnelykke, Klaus (University of Copenhagen) ;
Bisgaard, Hans (University of Copenhagen) ;
Sunyer, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lehtimäki, Terho (Tampere University) ;
Arseneault, Louise (Duke University School of Medicine) ;
Standl, Marie (Helmholtz Zentrum München) ;
Heinrich, Joachim (University of Melbourne) ;
Boden, Joseph (University of Otago Christchurch) ;
Pearson, John (University of Otago Christchurch) ;
Horwood, L. John (University of Otago Christchurch) ;
Kennedy, Martin (University of Otago Christchurch) ;
Poulton, Richie (University of Otago) ;
Eaves, Lindon J. (Virginia Institute for Psychiatric and Behavioral Genetics) ;
Maes, Hermine H. (Virginia Commonwealth University) ;
Hewitt, John (University of Colorado Boulder) ;
Copeland, William E. (University of Vermont) ;
Costello, Elizabeth J. (Duke University) ;
Williams, Gail M. (The University of Queensland) ;
Wray, Naomi R (University of Queensland) ;
Järvelin, Marjo-Riitta (University of Oulu) ;
McGue, Matt (University of Minnesota) ;
Iacono, William (University of Minnesota) ;
Caspi, Avshalom (King's College London) ;
Moffitt, Terrie E. (King's College London) ;
Whitehouse, Andrew (The University of Western Australia) ;
Pennell, Craig E. (The University of Newcastle) ;
Klump, Kelly L. (Michigan State University) ;
Burt, S. Alexandra (Michigan State University) ;
Dick, Danielle M. (Virginia Commonwealth University) ;
Reichborn-Kjennerud, Ted (University of Oslo) ;
Martin, Nicholas G (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Medland, Sarah Elizabeth (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Vrijkotte, Tanja (University of Amsterdam) ;
Kaprio, Jaakko (University of Helsinki) ;
Tiemeier, Henning (Harvard TH Chan School of Public Health) ;
Smith, George Davey (University of Bristol) ;
Hartman, Catharina A. (University of Groningen) ;
Oldehinkel, Albertine J (University of Groningen) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lichtenstein, Paul (Karolinska Institutet (Estocolm, Suècia)) ;
Lundström, Sebastian (University of Gothenburg) ;
Plomin, Robert (King's College London) ;
Bartels, Meike (Amsterdam Public Health Research Institute) ;
Nivard, Michel G. (Vrije Universiteit Amsterdam) ;
Boomsma, Dorret I (Amsterdam Public Health Research Institute)
Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. [...]
2021 -  10.1038/s41398-021-01480-x
Translational psychiatry, Vol. 11 (july 2021)
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12.
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11 p, 659.2 KB |
Survival and adverse events of elderly patients treated with sorafenib for hepatocellular carcinoma
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Soria, Anna (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Calvo, Mariona (Institut Català d'Oncologia) ;
Casas, Meritxell (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vidales, Zara (Institut Català d'Oncologia) ;
Muñoz-Martínez, S (Hospital Clínic i Provincial de Barcelona) ;
Sapena, Victor (Hospital Universitari Vall d'Hebron) ;
Puigvehí, Marc (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Canillas, Lidia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Guardeño, Raquel (Institut Català d'Oncologia) ;
Gallego, Adolfo (Institut d'Investigació Biomèdica Sant Pau) ;
Mínguez Rosique, Beatriz (Hospital Universitari Vall d'Hebron) ;
Horta Sangenís, Diana (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Clos, Ariadna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montoliu, Silvia (Hospital Universitari Joan XXIII de Tarragona) ;
Roget, Mercè (Consorci Sanitari de Terrassa) ;
Reig, María (Hospital Clínic i Provincial de Barcelona) ;
Vergara, Mercedes (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
The first-line treatment for advanced hepatocellular carcinoma (HCC) is atezolizumab plus bevacizumab, but its availability is not universal and elderly patients are underrepresented in clinical trials. [...]
2022 - 10.3389/fonc.2022.829483
Frontiers in Oncology, Vol. 12 (august 2022)
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13.
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14 p, 2.3 MB |
Prenatal environmental exposures associated with sex differences in childhood obesity and neurodevelopment
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Cáceres, Alejandro (Universitat Politècnica de Catalunya. Escola d'Enginyeria de Barcelona Est) ;
Carreras-Gallo, Natàlia (Barcelona Institute for Global Health (ISGlobal)) ;
Andrusaityte, Sandra (Vytautas Magnus University. Department of Environmental Science) ;
Bustamante, Mariona (Centre de Regulació Genòmica) ;
Carracedo, Ángel (Fundación Pública Galega de Medicina Xenómica) ;
Chatzi, Leda (University of Southern California. Department of Preventive Medicine) ;
Dwaraka, Varun B. (TruDiagnostic) ;
Grazuleviciene, Regina (Vytautas Magnus University. Department of Environmental Science) ;
Gutzkow, Kristine Bjerve (Norwegian Institute of Public Health) ;
Lepeule, Johanna (Université Grenoble-Alpes) ;
Maitre, Léa (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Mendez, Tavis L. (TruDiagnostic) ;
Nieuwenhuijsen, Mark (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Slama, Remy (Université Grenoble-Alpes) ;
Smith, Ryan (TruDiagnostic) ;
Stratakis, Nikos (Barcelona Institute for Global Health (ISGlobal)) ;
Thomsen, Cathrine (Norwegian Institute of Public Health) ;
Urquiza, Jose (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Went, Hannah (TruDiagnostic) ;
Wright, John (Bradford Teaching Hospitals NHS Foundation Trust) ;
Yang, Tiffany (Bradford Teaching Hospitals NHS Foundation Trust) ;
Casas, Maribel (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Vrijheid, Martine (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
González, Juan Ramón (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
Obesity and neurodevelopmental delay are complex traits that often co-occur and differ between boys and girls. Prenatal exposures are believed to influence children's obesity, but it is unknown whether exposures of pregnant mothers can confer a different risk of obesity between sexes, and whether they can affect neurodevelopment. [...]
2023 - 10.1186/s12916-023-02815-9
BMC Medicine, Vol. 21 (April 2023) , art. 142
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33 p, 892.7 KB |
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
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Mullins, Niamh ;
Kang, JooEun ;
Campos, Adrian I. ;
Coleman, Jonathan R.I. ;
Edwards, Alexis C. ;
Galfalvy, Hanga ;
Levey, Daniel F. ;
Lori, Adriana ;
Shabalin, Andrey ;
Starnawska, Anna ;
Su, Mei-Hsin ;
Watson, Hunna J. ;
Adams, Mark ;
Awasthi, Swapnil ;
Gandal, Michael ;
Hafferty, Jonathan D. ;
Hishimoto, Akitoyo ;
Kim, Minsoo ;
Okazaki, Satoshi ;
Otsuka, Ikuo ;
Ripke, Stephan ;
Ware, Erin B. ;
Bergen, Andrew W. ;
Berrettini, Wade H. ;
Bohus, Martin ;
Brandt, Harry ;
Chang, Xiao ;
Chen, Wei J. ;
Chen, Hsi-Chung ;
Crawford, Steven ;
Crow, Scott ;
DiBlasi, Emily ;
Duriez, Philibert ;
Fernández-Aranda, Fernando (Hospital Universitari de Bellvitge) ;
Fichter, Manfred M. ;
Gallinger, Steven ;
Glatt, Stephen J. ;
Gorwood, Philip ;
Guo, Yiran ;
Hakonarson, Hakon ;
Halmi, Katherine A. ;
Hwu, Hai-Gwo ;
Jain, Sonia ;
Jamain, Stéphane ;
Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge) ;
Johnson, Craig ;
Kaplan, Allan S. ;
Kaye, Walter H. ;
Keel, Pamela K. ;
Kennedy, James L. ;
Klump, Kelly L. ;
Li, Dong (Children's Hospital of Philadelphia (Pennsilvània)) ;
Liao, Shih-Cheng ;
Lieb, Klaus ;
Lilenfeld, Lisa ;
Liu, Chih-Min ;
Magistretti, Pierre J. ;
Marshall, Christian R. ;
Mitchell, James E. ;
Monson, Eric T. ;
Myers, Richard M. ;
Pinto, Dalila ;
Powers, Abigail ;
Ramoz, Nicolas ;
Roepke, Stefan ;
Rozanov, Vsevolod ;
Scherer, Stephen W. ;
Schmahl, Christian ;
Sokolowski, Marcus ;
Strober, Michael ;
Thornton, Laura M. ;
Treasure, Janet ;
Tsuang, Ming T. ;
Witt, Stephanie H. ;
Woodside, D. Blake ;
Yilmaz, Zeynep ;
Zillich, Lea ;
Adolfsson, Rolf ;
Agartz, Ingrid ;
Air, Tracy M. ;
Alda, Martin ;
Alfredsson, Lars ;
Andreassen, Ole A. ;
Anjorin, Adebayo ;
Appadurai, Vivek ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron) ;
Van der Auwera, Sandra ;
Azevedo, M. Helena ;
Bass, Nicholas ;
Bau, Claiton Henrique Dotto ;
Baune, Bernhard T. ;
Bellivier, Frank ;
Berger, Klaus ;
Biernacka, Joanna M. ;
Bigdeli, Tim B. ;
Binder, Elisabeth B. ;
Boehnke, Michael ;
Boks, Marco P. ;
Bosch, Rosa (Hospital Universitari Vall d'Hebron) ;
Braff, David L. ;
Bryant, Richard ;
Budde, Monika ;
Byrne, Enda M. ;
Cahn, Wiepke ;
Casas Brugué, Miquel (Hospital Universitari Vall d'Hebron) ;
Castelao, Enrique ;
Cervilla, Jorge A. ;
Chaumette, Boris ;
Cichon, Sven ;
Corvin, Aiden ;
Craddock, Nicholas ;
Craig, David ;
Degenhardt, Franziska ;
Djurovic, Srdjan ;
Edenberg, Howard J. ;
Fanous, Ayman H. ;
Foo, Jerome C. ;
Forstner, Andreas J. ;
Frye, Mark ;
Fullerton, Janice M. ;
Gatt, Justine M. ;
Gejman, Pablo V. ;
Giegling, Ina ;
Grabe, Hans J. ;
Green, Melissa J. ;
Grevet, Eugenio H. ;
Grigoroiu-Serbanescu, Maria ;
Gutierrez, Blanca ;
Guzman-Parra, Jose ;
Hamilton, Steven P. ;
Hamshere, Marian L. ;
Hartmann, Annette ;
Hauser, Joanna ;
Heilmann-Heimbach, Stefanie ;
Hoffmann, Per ;
Ising, Marcus ;
Jones, Ian ;
Jones, Lisa A. ;
Jonsson, Lina ;
Kahn, René S. ;
Kelsoe, John R. ;
Kendler, Kenneth S. ;
Kloiber, Stefan ;
Koenen, Karestan C. ;
Kogevinas, M ;
Konte, Bettina ;
Krebs, Marie-Odile ;
Landén, Mikael ;
Lawrence, Jacob ;
Leboyer, Marion ;
Lee, Phil H. ;
Levinson, Douglas F. ;
Liao, Calwing ;
Lissowska, Jolanta ;
Lucae, Susanne ;
Mayoral-Cleries, Fermín ;
McElroy, Susan L. ;
McGrath, Patrick ;
McGuffin, Peter ;
McQuillin, Andrew ;
Medland, Sarah E. ;
Mehta, Divya ;
Melle, Ingrid ;
Milaneschi, Yuri ;
Mitchell, Philip B. ;
Molina, Esther ;
Morken, Gunnar ;
Bo Mortensen, Preben ;
Müller-Myhsok, Bertram ;
Nievergelt, Caroline ;
Nimgaonkar, Vishwajit ;
Nöthen, Markus M. ;
O'Donovan, Michael C. (Cardiff University) ;
Ophoff, Roel A. ;
Owen, Michael J. ;
Pato, Carlos ;
Pato, Michele T. ;
Penninx, Brenda WJH ;
Pimm, Jonathan ;
Pistis, Giorgio ;
Potash, James B. ;
Power, Robert A. ;
Preisig, Martin ;
Quested, Digby ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Reif, Andreas ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rietschel, Marcella ;
Rivera, Margarita ;
Roberts, Andrea ;
Roberts, Gloria ;
Rouleau, Guy A. ;
Rovaris, Diego L. ;
Rujescu, Dan ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Sanders, Alan R. ;
Schofield, Peter R. ;
Schulze, Thomas G. ;
Scott, Laura J. ;
Serretti, Alessandro ;
Shi, Jianxin ;
Shyn, Stanley I. ;
Sirignano, Lea ;
Sklar, Pamela ;
Smeland, Olav B. ;
Smoller, Jordan W. ;
Sonuga-Barke, Edmund J.S. ;
Spalletta, Gianfranco ;
Strauss, John S. ;
Świątkowska, Beata ;
Trzaskowski, Maciej ;
Turecki, Gustavo ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron) ;
Vincent, John B. ;
Völzke, Henry ;
Walters, James T.R. ;
Weickert, Cynthia Shannon ;
Weickert, Thomas W. ;
Weissman, Myrna M. ;
Williams, Leanne M. ;
Wray, Naomi R. ;
Zai, Clement C. ;
Ashley-Koch, Allison E. ;
Beckham, Jean C. ;
Hauser, Elizabeth R. ;
Hauser, Michael A. ;
Kimbrel, Nathan A. ;
Lindquist, Jennifer H. ;
McMahon, Benjamin ;
Oslin, David W. ;
Qin, Xuejun ;
Agerbo, Esben ;
Børglum, Anders D. ;
Breen, Gerome ;
Erlangsen, Annette ;
Esko, Tõnu ;
Gelernter, Joel ;
Hougaard, David M. ;
Kessler, Ronald C. ;
Kranzler, Henry R. ;
Li, Qingqin S. ;
Martin, Nicholas G. ;
McIntosh, Andrew M. ;
Mors, Ole ;
Nordentoft, Merete ;
Olsen, Catherine M. ;
Porteous, David ;
Ursano, Robert J. ;
Wasserman, Danuta ;
Werge, Thomas ;
Whiteman, David C. ;
Bulik, Cynthia M. ;
Coon, Hilary ;
Demontis, Ditte ;
Docherty, Anna R. ;
Kuo, Po-Hsiu ;
Lewis, Cathryn M. ;
Mann, J. John ;
Rentería, Miguel E. ;
Smith, Daniel J. ;
Stahl, Eli A. ;
Stein, Murray B. ;
Streit, Fabian ;
Willour, Virginia ;
Ruderfer, Douglas M. ;
Universitat Autònoma de Barcelona
Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. [...]
2021 - 10.1016/j.biopsych.2021.05.029
Biological psychiatry, Vol. 91 (september 2021) , p. 313-327
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21 p, 2.6 MB |
Repurposing Disulfiram as an Antifungal Agent : Development of a New Disulfiram Vaginal Mucoadhesive Gel
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Lajarin-Reinares, Maria (Reig Jofre Laboratories) ;
Naveira-Souto, Iria (Reig Jofre Laboratories) ;
Mallandrich, Mireia (Universitat de Barcelona. Departament de Farmàcia) ;
Suñer-Carbó, Joaquim (Universitat de Barcelona. Departament de Farmàcia) ;
Llagostera Casas, Montserrat (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Calvo Torras, Ma. de los Ángeles (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Fernandez-Campos, Francisco (Labiana Pharmaceuticals)
Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative to treat vaginal candidiasis. [...]
2023 - 10.3390/pharmaceutics15051436
Pharmaceutics, Vol. 15 (may 2023)
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15 p, 854.2 KB |
The impact of attention-deficit/hyperactivity disorder and specific learning disorders on academic performance in Spanish children from a low-middle- and a high-income population
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Español-Martín, Gemma (Hospital Universitari Vall d'Hebron) ;
Pagerols, Mireia (Universitat de Barcelona) ;
Prat, Raquel (Universitat de Vic) ;
Rivas, Cristina (Hospital Sant Joan de Déu (Manresa)) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona) ;
Bosch, Rosa (Hospital Sant Joan de Déu (Manresa))
Past research has demonstrated that attention-deficit/hyperactivity disorder (ADHD), specific learning disorders (SLD), and socioeconomic status (SES) affect a host of educational outcomes. However, there are no studies examining whether SES moderates the association between these neurodevelopmental disorders (ND) and the academic achievement of children and adolescents. [...]
2023 - 10.3389/fpsyt.2023.1136994
Frontiers in psychiatry, Vol. 14 (april 2023)
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17.
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14 p, 2.0 MB |
Quality of life with palbociclib plus fulvestrant versus placebo plus fulvestrant in postmenopausal women with endocrine-sensitive hormone receptor-positive and HER2-negative advanced breast cancer : patient-reported outcomes from the FLIPPER trial
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Tibau Martorell, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez, M. Teresa ;
Ramos, Manuel ;
de la Cruz Merino, Luis ;
Santaballa, Ana ;
O'Connor, Miriam ;
Martínez-Jañez, Noelia ;
Moreno, Fernando ;
Fernández, Isaura ;
Virizuela, Juan Antonio ;
Alarcón, Jesús ;
de la Haba Rodríguez, Juan Rafael ;
Sánchez-Rovira, Pedro ;
Albacar, Cinta Rosa ;
Bueno Muiño, Coralia ;
Kelly, Catherine ;
Casas, Maribel ;
Bezares, Susana ;
Rosell, Libertad ;
Albanell Mestres, Joan (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
In the FLIPPER trial, palbociclib/fulvestrant significantly improved progression-free survival (PFS) compared with placebo/fulvestrant in postmenopausal women with HR+/HER2− advanced breast cancer (ABC). [...]
2023 - 10.1177/17588359221148921
Therapeutic Advances in Medical Oncology, Vol. 15 (january 2023)
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12 p, 1.2 MB |
Caffeine and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus : Findings from Clinical and Experimental Studies
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Alcubierre, Nuria (Avantmèdic (LLeida)) ;
Granado-Casas, Minerva (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Bogdanov, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramos, Hugo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castelblanco, Esmeralda (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Real, Jordi (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Rubinat, Esther (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Traveset, Alicia (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Hernández, Marta (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Jurjo, Carmen (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Vioque, Jesús (Instituto de Salud Carlos III) ;
Navarrete-Muñoz, Eva Maria (Instituto de Investigación Sanitaria y Biomédica de Alicante) ;
Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The aim of this study was to assess the potential benefits of caffeine intake in protecting against the development of diabetic retinopathy (DR) in subjects with type 2 diabetes (T2D). Furthermore, we tested the effect of topical administration of caffeine on the early stages of DR in an experimental model of DR. [...]
2023 - 10.3390/nu15051169
Nutrients, Vol. 15 (february 2023)
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Effectiveness of medical nutrition therapy in adolescents with type 1 diabetes : a systematic review
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Granado-Casas, Minerva (Institut d'Investigació Biomèdica Sant Pau) ;
Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández, Marta (Hospital Universitari Arnau de Vilanova) ;
Rojo López, Marina Idalia (Institut d'Investigació Biomèdica Sant Pau) ;
Julve i Gil, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau)
BACKGROUND: Medical nutrition therapy (MNT) has an integral role in overall diabetes management. During adolescence, consideration of physiological and psychosocial changes is essential for implementing an optimal diabetes treatment. [...]
2022 - 10.1038/s41387-022-00201-7
Nutrition & diabetes, Vol. 12 Núm. 1 (december 2022) , p. 24
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