UAB Digital Repository of Documents 6 records found  Search took 0.00 seconds. 
1.
16 p, 1.9 MB Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients / Ji, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Lin, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Shen, S. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; Chen, C. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Li, Y. (Department of Biostatistics. University of Michigan) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Su, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Jiang, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Fan, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Guan, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Shafer, A. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Bjaanæs, M.M. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Wei, Y. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Zhang, R. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Chen, F. (Jiangsu Key Lab of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, D.C. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Universitat Autònoma de Barcelona
Tripartite motif containing 27 (TRIM27) is highly expressed in lung cancer, including non-small-cell lung cancer (NSCLC). Here, we profiled DNA methylation of lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tumours from 613 early-stage NSCLC patients and evaluated associations between CpG methylation of TRIM27 and overall survival. [...]
2020 - 10.1002/1878-0261.12785
Molecular Oncology, Vol. 14 Núm. 11 (january 2020) , p. 2759-2774  
2.
12 p, 1.2 MB Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects / Zhang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Chen, C. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; Shen, S. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Lai, L. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Lin, L. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Li, Y. (Department of Biostatistics. University of Michigan) ; Guo, Y. (Department of Biostatistics. Harvard T. H. Chan School of Public Health) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Liu, L. (Department of Preventive Medicine. Medical School of Ningbo University) ; Su, L. (Department of Environmental Health. Harvard T. H. Chan School of Public Health) ; Shafer, A. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Fleischer, T. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Moksnes Bjaanæs, M. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Wang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences. Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Physiological Sciences Department. School of Medicine and Health Sciences. University of Barcelona) ; Wei, Y. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Chen, F. (Jiangsu Key Laboratory of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, D.C. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Universitat Autònoma de Barcelona
Background: DNA methylation and gene expression are promising biomarkers of various cancers, including non-small cell lung cancer (NSCLC). Besides the main effects of biomarkers, the progression of complex diseases is also influenced by gene-gene (G×G) interactions. [...]
2020 - 10.1016/j.chest.2020.01.048
Chest, Vol. 158 Núm. 2 (august 2020) , p. 808-819  
3.
21 p, 2.7 MB Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients / Chen, C. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Wei, Y. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Lin, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Lai, L. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Shen, S. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Su, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Shafer, A. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Fleischer, T. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Bjaanæs, M.M. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Wang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zhang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Chen, F. (Jiangsu Key Lab of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, D.C. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Universitat Autònoma de Barcelona
DNA methylation changes during aging, but it remains unclear whether the effect of DNA methylation on lung cancer survival varies with age. Such an effect could decrease prediction accuracy and treatment efficacy. [...]
2020 - 10.18632/aging.103284
Aging (Albany NY), Vol. 12 Núm. 11 (15 2020) , p. 10642-10662  
4.
14 p, 2.0 MB Differential Immunodominance Hierarchy of CD8 + T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection / Adland, Emily ; Hill, Matilda ; Lavandier, Nora ; Csala, Anna ; Edwards, Anne ; Chen, Fabian ; Radkowski, Marek ; Kowalska, Justyna D. ; Paraskevis, Dimitrios ; Hatzakis, Angelos ; Valenzuela-Ponce, Humberto ; Pfafferott, Katja ; Williams, Ian ; Pellegrino, Pierre ; Borrow, Persephone ; Mori, Masahiko ; Rockstroh, Jürgen ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Tudor-Williams, Gareth ; Frater, John ; Stryhn, Anette ; Buus, Soren ; Teran, Gustavo Reyes ; Mallal, Simon ; John, Mina ; Buchbinder, Susan ; Kirk, Gregory ; Martin, Jeffrey ; Michael, Nelson ; Fellay, Jacques ; Deeks, Steve ; Walker, Bruce ; Avila-Rios, Santiago ; Cole, David ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrington, Mary ; Goulder, Philip ; Universitat Autònoma de Barcelona
The well-characterized association between HLA-B*27:05 and protection against HIV disease progression has been linked to immunodominant HLA-B*27:05-restricted CD8 + T-cell responses toward the conserved Gag KK10 (residues 263 to 272) and polymerase (Pol) KY9 (residues 901 to 909) epitopes. [...]
2018 - 10.1128/JVI.01685-17
Journal of Virology, Vol. 92 (january 2018)  
5.
11 p, 1018.7 KB Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects / Hancock, Gemma ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kopycinski, Jakub ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Giannoulatou, Eleni (University of New South Wales) ; Rose, Annie ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hayton, Emma-Jo ; Crook, Alison ; Morgan, Catharine ; Angus, Brian ; Chen, Fabian ; Yang, Hongbing ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomas ; Dorrell, Lucy ; Universitat Autònoma de Barcelona
Introduction : Vaccines may be key components of a curative strategy for HIV-1. We investigated whether a novel immunogen, HIVconsv, designed to re-direct T cell responses to conserved viral epitopes, could impact the HIV-1 reservoir in chronic antiretroviral therapy (ART)-treated subjects when delivered by modified vaccinia virus Ankara (MVA). [...]
2017 - 10.7448/IAS.20.1.21171
Journal of the International AIDS Society, Vol. 20 (may 2017)  
6.
15 p, 241.3 KB The power and the promise of cell reprogramming : personalized autologous body organ and cell transplantation / Álvarez Palomo, Ana Belén (Universitat de Barcelona. Departament de Ciències Fisiològiques I) ; Lucas, Michaela (University of Western Australia. School of Medicine and Pharmacology) ; Dilley, Rodney J. (University of Western Australia. School of Surgery) ; McLenachan, Samuel (University of Western Australia. Centre for Ophthalmology and Visual Science) ; Chen, Fred Kuanfu (University of Western Australia. Centre for Ophthalmology and Visual Science) ; Requena, Jordi (Universitat de Barcelona. Departament de Ciències Fisiològiques I) ; Sal, Marti Farrera (Universitat de Barcelona. Departament de Ciències Fisiològiques I) ; Lucas, Andrew (Murdoch University. Institute for Immunology and Infectious Diseases) ; Álvarez Angulo, Iñaki (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jaraquemada, Dolores (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Edel, Michael J. (Universitat de Barcelona. Departament de Ciències Fisiològiques I)
Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) or direct reprogramming to desired cell types are powerful and new in vitro methods for the study of human disease, cell replacement therapy, and drug development. [...]
2014 - 10.3390/jcm3020373
Journal of clinical medicine, Vol. 3 (June 2014) , p. 373-387  

See also: similar author names
2 Chen, Fabian
1 Chen, Fred Kuanfu
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