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17 p, 2.1 MB |
LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells
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Actis Dato, Virginia (Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Benitez Amaro, Aleyda (Institut d'Investigació Biomèdica Sant Pau) ;
Gonzalo Calvo, David de (Instituto de Salud Carlos III) ;
Vazquez, M. (Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Bonacci, G. (Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Llorente-Cortés, V. (Instituto de Salud Carlos III) ;
Chiabrando, G.A. (Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Universitat Autònoma de Barcelona
The cardiovascular disease (CVD) frequently developed during metabolic syndrome and type-2 diabetes mellitus is associated with increased levels of aggregation-prone small LDL particles. Aggregated LDL (aggLDL) internalization is mediated by low-density lipoprotein receptor-related protein-1 (LRP1) promoting intracellular cholesteryl ester (CE) accumulation. [...]
2020 -  10.3390/cells9010182
Cells, Vol. 9 Núm. 1 (october 2020) , p. 419
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14 p, 4.1 MB |
Targeting cholesteryl ester accumulation in the heart improves cardiac insulin response
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Actis Dato, Virginia (Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Benitez Amaro, Aleyda (Institut d'Investigació Biomèdica Sant Pau) ;
García Rodríguez, Jesús Eduardo (Institut d'Investigació Biomèdica Sant Pau) ;
Claudi, Lene (Institut d'Investigació Biomèdica Sant Pau) ;
La Chica, María Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Iborra, A. (Universitat Autònoma de Barcelona) ;
Escolà-Gil, Joan Carles (Institut d'Investigació Biomèdica Sant Pau) ;
Guerra Ramos, José María (Institut d'Investigació Biomèdica Sant Pau) ;
Samouillan, V. (CIRIMAT. Université de Toulouse. Université Paul Sabatier. Equipe PHYPOL) ;
Enrich, C. (Centre de Recerca Biomèdica CELLEX. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ;
Chiabrando, G.A (Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI)) ;
Llorente-Cortés, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Background: Antibodies against the P3 sequence (Gly1127-Cys1140) of LRP1 (anti-P3 Abs) specifically block cholesteryl ester (CE) accumulation in vascular cells. LRP1 is a key regulator of insulin receptor (InsR) trafficking in different cell types. [...]
2022 - 10.1016/j.biopha.2022.113270
Biomedicine & pharmacotherapy, Vol. 152 (august 2022) , p. 113270
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23 p, 844.8 KB |
Can current moisture responses predict soil CO₂ efflux under altered precipitation regimes? A synthesis of manipulation experiments
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Vicca, Sara (Universiteit Antwerpen. Departement Biologie) ;
Bahn, Michael. (Universität Innsbruck. Institut für Ökologie) ;
Estiarte, Marc (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Loon, E. E. van (Universiteit van Amsterdam. Institute for Biodiversity and Ecosystem Dynamics) ;
Vargas, R. (University of Delaware. Department of Plant and Soil Sciences) ;
Alberti, G. (Università di Udine) ;
Ambus, P. (Danmarks tekniske universitet. Institut for Kemisk og Biokemisk Teknologi) ;
Arain, M. A. (McMaster Centre for Climate Change) ;
Beier, Claus (Norsk institutt for vannforskning) ;
Bentley, L. P. (Texas Tech University. Department of Biological Sciences) ;
Borken, W. (Universität Bayreuth. Lehrstuhl für Bodenökologie) ;
Buchmann, Nina (Eidgenössischen Technischen Hochschule Zürich. Institut für Umweltsystemwissenschaften) ;
Collins, Scott L. (University of New Mexico. Biology Department) ;
de Dato, Giovanbattista (Università degli studi della Tuscia di Viterbo. Dipartimento per l'Innovazione nei sistemi Biologici, Agro-alimentari e. Forestali) ;
Dukes, Jeffrey S. (Purdue University. Department of Forestry and Natural Resources) ;
Escolar, C. (Universidad Rey Juan Carlos. Área de Biodiversidad y Conservación) ;
Fay, P. (Grassland Soil and Water Research Laboratory (U.S.)) ;
Guidolotti, Gabriele (Università degli studi della Tuscia di Viterbo. Dipartimento per l'Innovazione nei sistemi Biologici, Agro-alimentari e. Forestali) ;
Hanson, Paul J (Oak Ridge National Laboratory) ;
Kahmen, A. (Eidgenössischen Technischen Hochschule Zürich. Institut für Agrarwissenschaften) ;
Kröel-Dulay, György (Hungarian Academy of Sciences. Institute of Ecology and Botany) ;
Ladreiter-Knauss, T. (Universität Innsbruck. Institut für Ökologie) ;
Larsen, Klaus Steenberg (Danmarks tekniske universitet. Institut for Kemisk og Biokemisk Teknologi) ;
Lellei-Kovacs, E. (Hungarian Academy of Sciences. Institute of Ecology and Botany) ;
Lebrija-Trejos, Edwin (Tel Aviv University. Department of Molecular Biology and Ecology of Plants) ;
Maestre, Fernando T (Universidad Rey Juan Carlos. Área de Biodiversidad y Conservación) ;
Marhan, S. (Universität Hohenheim. Institut für Bodenkunde und Standortslehre) ;
Marshall, M. (Centre for Ecology and Hydrology (Great Britain)) ;
Meir, Patrick. (University of Edinburgh. School of GeoSciences) ;
Miao, Y. (Henan da xue) ;
Muhr, J. (Max-Planck. Institut für Biogeochemie) ;
Niklaus, P. A. (Universität Zürich. Institut für Evolutionsbiologie und Umweltwissenschaften) ;
Ogaya Inurrigarro, Romà (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Peñuelas, Josep (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Poll, Christian (Universität Hohenheim. Institut für Bodenkunde und Standortslehre) ;
Rustad, L. E. (United States. Forest Service. Northeastern Research Station) ;
Savage, K. (Woods Hole Research Center (Woods Hole, Mass.)) ;
Schindlbacher, A. (Bundesforschungs- und Ausbildungszentrum für Wald, Naturgefahren und Landschaft (Austria)) ;
Schmidt, I. K. (Køvenhavns universitet. Department of Geosciences and Natural Resource Management) ;
Smith, A. R. (Centre for Ecology and Hydrology (Great Britain)) ;
Sotta, E. D. (Embrapa Amapá Caixa Postal) ;
Suseela, V. (Purdue University. Department of Forestry and Natural Resources) ;
Tietema, A. (Universiteit van Amsterdam. Institute for Biodiversity and Ecosystem Dynamics) ;
Gestel, N. van (Texas Tech University. Department of Biological Sciences) ;
Straaten, O. van (Büsgen-Institut. Ökopedologie der Tropen und Subtropen) ;
Wan, S. (Henan da xue) ;
Weber, U. (Max-Planck. Institut für Biogeochemie) ;
Janssens, Ivan (Universiteit Antwerpen. Departement Biologie)
As a key component of the carbon cycle, soil CO₂ efflux (SCE) is being increasingly studied to improve our mechanistic understanding of this important carbon flux. Predicting ecosystem responses to climate change often depends on extrapolation of current relationships between ecosystem processes and their climatic drivers to conditions not yet experienced by the ecosystem. [...]
2014 - 10.5194/bg-11-2991-2014
Biogeosciences, Vol. 11 Issue 11 (Juny 2014) , p. 2991-3013
2 documents
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