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12 p, 1.3 MB |
Real-time genomics for One Health
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Urban, Lara (Helmholtz Zentrum Muenchen) ;
Perlas Puente, Albert (Helmholtz Zentrum Muenchen) ;
Francino, Olga (Nano1Health, S.L.) ;
Martí-Carreras, Joan (Nano1Health, S.L.) ;
Muga, Brenda (University of Otago. Department of Anatomy) ;
Mwangi, Jenniffer W. (Machakos University. Biological Department) ;
Okalebo, Laura Boykin (BioTeam, Inc. (USA)) ;
Stanton, Jo-Ann (University of Otago. Department of Anatomy) ;
Black, Amanda (Lincoln University. Bioprotection Aotearoa) ;
Waipara, Nick (Plant and Food Research (New Zealand)) ;
Fontsere, Claudia (University of Copenhagen. The Globe Institute. Center for Evolutionary Hologenomics) ;
Eccles, David (Malaghan Institute of Medical Research. Hugh Green Cytometry Centre) ;
Urel, Harika (Helmholtz Zentrum Muenchen) ;
Reska, Tim (Helmholtz Zentrum Muenchen) ;
Morales, Hernan (University of Copenhagen. The Globe Institute. Center for Evolutionary Hologenomics) ;
Palmada-Flores, Marc (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Watsa, Mrinalini (San Diego Zoo Wildlife Alliance) ;
Libke, Zane (Instituto Nacional de Biodiversidad (Ecuador)) ;
Erkenswick, Gideon (Field Projects International (USA)) ;
van Oosterhout, Cock (University of East Anglia)
The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. [...]
2023 -  10.15252/msb.202311686
Molecular systems biology, Vol. 19, Issue 6 (June 2023) , art. e11686
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11 p, 1.8 MB |
Clonal Spread and Intra- and Inter-Species Plasmid Dissemination Associated With Klebsiella pneumoniae Carbapenemase-Producing Enterobacterales During a Hospital Outbreak in Barcelona, Spain
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Marí-Almirall, Marta (Hospital Clínic i Provincial de Barcelona) ;
Ferrando, Núria (Hospital Clínic i Provincial de Barcelona) ;
Fernández, Mariana José (Hospital Clínic i Provincial de Barcelona) ;
Cosgaya, Clara (Hospital Clínic i Provincial de Barcelona) ;
Viñes, Joaquim (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular (SVGM)) ;
Rubio, Elisa (Hospital Clínic i Provincial de Barcelona) ;
Cuscó, Anna (Universitat Autònoma de Barcelona. Vetgenomics) ;
Muñoz, Laura (Hospital Clínic i Provincial de Barcelona) ;
Pellice, Martina (Hospital Clínic i Provincial de Barcelona) ;
Vergara, Andrea (Hospital Clínic i Provincial de Barcelona) ;
Campo, Irene (Hospital Clínic i Provincial de Barcelona) ;
Rodríguez-Serna, Laura (Hospital Clínic i Provincial de Barcelona) ;
Santana, Gemina (Hospital Clínic i Provincial de Barcelona) ;
Del Río, Ana (Hospital Clínic i Provincial de Barcelona) ;
Francino, Olga (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular (SVGM)) ;
Ciruela, Pilar (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Ballester, Frederic (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Marco, Francesc (Hospital Clínic i Provincial de Barcelona) ;
Martínez, José Antonio (Hospital Clínic i Provincial de Barcelona) ;
Soriano, Álex (Hospital Clínic i Provincial de Barcelona) ;
Pitart, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Vila Estapé, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Roca, Ignasi (Hospital Clínic i Provincial de Barcelona)
Objectives: The study aimed to characterize the clonal spread of resistant bacteria and dissemination of resistance plasmids among carbapenem-resistant Enterobacterales at a tertiary hospital in Catalonia, Spain. [...]
2021 - 10.3389/fmicb.2021.781127
Frontiers in microbiology, Vol. 12 (november 2021)
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15 p, 2.7 MB |
Concordance between Antimicrobial Resistance Phenotype and Genotype of Staphylococcus pseudintermedius from Healthy Dogs
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Viñes, Joaquim (Universitat Autònoma de Barcelona. Vetgenomics) ;
Fábregas, Norma (Universitat Autònoma de Barcelona. Vetgenomics) ;
Pérez, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Cuscó, Anna (Universitat Autònoma de Barcelona. Vetgenomics) ;
Fonticoba, Rocío (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Francino, Olga (Universitat Autònoma de Barcelona. Vetgenomics) ;
Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Migura-Garcia, Lourdes (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Staphylococcus pseudintermedius, a common commensal canine bacterium, is the main cause of skin infections in dogs and is a potential zoonotic pathogen. The emergence of methicillin-resistant S. pseudintermedius (MRSP) has compromised the treatment of infections caused by these bacteria. [...]
2022 - 10.3390/antibiotics11111625
Antibiotics, Vol. 11 (november 2022)
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13 p, 1.4 MB |
Identification of Leishmania infantum Epidemiology, Drug Resistance and Pathogenicity Biomarkers with Nanopore Sequencing
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Martí-Carreras, Joan (Nano1Health S.L.) ;
Carrasco, Marina (Nano1Health S.L.) ;
Gómez-Ponce, Marcel (Nano1Health S.L.) ;
Noguera-Julian, Marc (Nano1Health S.L.) ;
Fisa, Roser (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Riera, Cristina (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Alcover, M. Magdalena (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Roura, Xavier (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari) ;
Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Francino, Olga (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular (SVGM))
The emergence of drug-resistant strains of the parasite Leishmania infantum infecting dogs and humans represents an increasing threat. L. infantum genomes are complex and unstable with extensive structural variations, ranging from aneuploidies to multiple copy number variations (CNVs). [...]
2022 - 10.3390/microorganisms10112256
Microorganisms, Vol. 10 (november 2022)
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4 p, 292.7 KB |
Whole-Genome Sequencing and De Novo Assembly of 67 Strains Isolated from the Skin of Healthy Dogs
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Fábregas, Norma (Universitat Autònoma de Barcelona. Vetgenomics) ;
Pérez, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Viñes, Joaquim (Universitat Autònoma de Barcelona. Vetgenomics) ;
Fonticoba, Rocío (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Cuscó, Anna (Universitat Autònoma de Barcelona. Vetgenomics) ;
Migura-Garcia, Lourdes (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Francino, Olga (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular (SVGM))
We have de novo assembled 67 genomes, with median values of 2. 6 Mbp size and 99. 43% completeness, 2,386 coding sequences, 19 complete rRNAs, 59 tRNAs, and 4 noncoding RNAs. We released 51 single-contig complete genomes and 16 genomes with a circular main contig using Nanopore sequencing.
2022 - 10.1128/mra.00039-22
Microbiology Resource Announcements, Vol. 11 (march 2022)
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215 p, 13.0 MB |
From the clinic to the farm : Applying sequencing and de novo assembly to characterize One-Health bacterial pathogens
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Viñes, Joaquim ;
Francino, Olga, dir. ;
Cuscó, Anna ;
Sánchez Bonastre, Armando, dir.
Les infeccions causades per bacteris resistents a múltiples antibiòtics son una amenaça tant per a la salut animal com la humana degut a la limitació en el tractament, la qual pot portar a complicacions clíniques severes, estades hospitalàries més llargues o, fins i tot, a la mort. [...]
Las infecciones causadas por bacterias resistentes a múltiples antibióticos son una amenaza tanto para la salud animal como la humana debido a la limitación en el tratamiento, la cual puede conllevar complicaciones clínicas severas, estancias hospitalarias más largar o incluso la muerte. [...]
Multi-drug resistant bacteria infections are a threat to animal and human health due to the limitation in treatment, which can lead to severe clinical complications, longer hospital stays, or even death. [...]
2021
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