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1.
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9 p, 526.0 KB |
Burden of refractory and unexplained chronic cough on patients' lives : a cohort study
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Puente, Luis (Hospital Universitario Gregorio Marañón) ;
Dávila, Ignacio (Hospital Clínico Universitario (Salamanca)) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ;
Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
Sola, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Nieto, María Luisa (Hospital Arnau de Vilanova (València)) ;
González-Barcala, Francisco-Javier (Universidad de Santiago de Compostela) ;
Cea-Calvo, Luis (Medical Affairs) ;
Sánchez-Jareño, Marta (Medical Affairs) ;
Rivas-Pardinas, Cristina (Medical Affairs) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Chronic cough (cough lasting for ≥8 weeks) can lead to significant impairment in quality of life (QoL). Using patient-reported outcomes, this cohort study assessed the perceived impact of chronic cough on QoL and everyday life in patients from outpatient hospital clinics with refractory chronic cough (RCC) or unexplained chronic cough (UCC). [...]
2023 -  10.1183/23120541.00425-2023
ERJ Open Research, Vol. 9 (september 2023)
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2.
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10 p, 1.8 MB |
A proposed approach to chronic airway disease (CAD) using therapeutic goals and treatable traits : A look to the future
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Pérez de Llano, Luis (University Hospital Lucus Augusti (Lugo, Galícia)) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Golpe, Rafael (University Hospital Lucus Augusti (Lugo, Galícia)) ;
Alvarez Gutiérrez, Francisco Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cisneros, Carolina (Hospital Universitario La Princesa (Madrid)) ;
Almonacid, Carlos (Hospital Universitario Ramón y Cajal (Madrid)) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
González-Barcala, Francisco-Javier (Universidade de Santiago de Compostela) ;
Ramos-Barbón, David (Institut d'Investigació Biomèdica Sant Pau) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
De Torres, Juan Pablo (Queen's University) ;
Casanova Macario, Ciro (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
García-Rivero, J. L. (Hospital de Laredo) ;
Rodriguez Hermosa, Juan Luis (Hospital Clínico San Carlos (Madrid)) ;
Calle Rubio, Myriam (Hospital Clínico San Carlos (Madrid)) ;
Soler-Cataluña, Juan José (Hospital Arnau de Vilanova (València)) ;
Cosio, Borja G (Clínica Quirón-Rotger) ;
Universitat Autònoma de Barcelona
Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes, but quite frequently overlap in some of their pathophysiological and clinical characteristics. [...]
2020 - 10.2147/COPD.S263430
International journal of COPD, Vol. 15 (2020) , p. 2091-2100
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3.
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6 p, 251.2 KB |
How reliably can algorithms identify eosinophilic asthma phenotypes using non-invasive biomarkers?
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Betancor, Diana (Hospital Universitario Fundación Jiménez Díaz) ;
Olaguibel, José María (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Rodrigo-Muñoz, José Manuel (Hospital Universitario Fundación Jiménez Díaz) ;
Arismendi, Ebymar (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Barranco, Pilar (Hospital Universitario La Paz (Madrid)) ;
Barroso, Blanca (Hospital Universitario Fundación Jiménez Díaz) ;
Bobolea, Irina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cárdaba, Blanca (Hospital Universitario Fundación Jiménez Díaz) ;
Cruz, María Jesús (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Curto Sánchez, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Del Pozo, Victoria (Hospital Universitario Fundación Jiménez Díaz) ;
González-Barcala, Francisco-Javier (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Martínez Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mullol, Joaquim (Universitat de Barcelona) ;
Muñoz Gall, Xavier (Hospital Universitari Vall d'Hebron) ;
Picado, Cesar (Universitat de Barcelona) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ;
Rial, Manuel Jorge (Complejo Hospitalario Universitario de A Coruña) ;
Soto-Retes, Lorena (Institut d'Investigació Biomèdica Sant Pau) ;
Valero, Antonio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Valverde-Monge, Marcela (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Sastre, Joaquin (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Asthma is a heterogeneous respiratory disease that encompasses different inflammatory and functional endophenotypes. Many non-invasive biomarkers has been investigated to its pathobiology. Heany et al proposed a clinical algorithm that classifies severe asthmatic patients into likely-eosinophilic phenotypes, based on accessible biomarkers: PBE, current treatment, FeNO, presence of nasal polyps (NP) and age of onset. [...]
2022 - 10.1002/clt2.12182
Clinical and translational allergy, Vol. 12, Issue 8 (August 2022) , art. e12182
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4.
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17 p, 1.5 MB |
Multi-ancestry genome-wide association study of asthma exacerbations
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Herrera-Luis, Esther (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Ortega, Victor E. (División de Medicina Respiratoria. Departamento de Medicina Interna. Mayo Clinic) ;
Ampleford, Elizabeth J. (Department of Internal Medicine. Center for Precision Medicine. Wake Forest School of Medicine) ;
Sio, Yang Yie (Department of Biological Sciences. National University of Singapore) ;
Granell, Raquel (MRC Integrative Epidemiology Unit (IEU). Population Health Sciences. Bristol Medical School. University of Bristol) ;
de Roos, Emmely (Department of Respiratory Medicine. Ghent University Hospital) ;
Terzikhan, Natalie (Department of Respiratory Medicine. Ghent University Hospital) ;
Vergara, Ernesto Elorduy (Institute of Computation Biology. Helmholtz Zentrum München. German Research Center for Environmental Health) ;
Hernandez-Pacheco, Natalia (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Perez-Garcia, Javier (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Martin-Gonzalez, Elena (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Lorenzo-Diaz, Fabian (Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias. Universidad de La Laguna) ;
Hashimoto, Simone (Department of Respiratory Medicine. Amsterdam University Medical Center. University of Amsterdam) ;
Brinkman, Paul (Department of Respiratory Medicine. Amsterdam University Medical Center. University of Amsterdam) ;
Jorgensen, Andrea L. (Department of Health Data Science. Institute of Population Health. University of Liverpool) ;
Yan, Qi (Department of Obstetrics and Gynecology. Columbia University Irving Medical Center) ;
Forno, Erick (Division of Pediatric Pulmonary Medicine. UPMC Children's Hospital of Pittsburgh. University of Pittsburgh) ;
Vijverberg, Susanne J. (Department of Paediatric Respiratory Medicine and Allergy. Emma's Children Hospital. Amsterdam UMC. University of Amsterdam) ;
Lethem, Ryan (MRC Integrative Epidemiology Unit (IEU). Population Health Sciences. Bristol Medical School. University of Bristol) ;
Espuela-Ortiz, Antonio (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Gorenjak, Mario (Center for Human Molecular Genetics and Pharmacogenomics. Faculty of Medicine. University of Maribor) ;
Eng, Celeste (Department of Medicine. University of California San Francisco) ;
González-Pérez, Ruperto (Unidad de Asma Grave. Servicio de Alergología. Hospital Universitario de Canarias.) ;
Hernández-Pérez, José M. (Hospital General de La Palma. Servicio de Neumología) ;
Poza-Guedes, Paloma (Hospital Universitario de Canarias. Unidad de Asma Grave. Servicio de Alergología) ;
Sardón, Olaia (Universidad del País Vasco. Departamento de Pediatría) ;
Corcuera, Paula (Hospital Universitario Donostia. Division of Pediatric Respiratory Medicine) ;
Hawkins, Greg A. (Department of Biochemistry. Wake Forest School of Medicine) ;
Marsico, Annalisa (Computational Health Center. Helmholtz Zentrum München. German Research Center for Environmental Health) ;
Bahmer, Thomas (Airway Research Center North (ARCN). Members of the Germany Center for Lung Research (DZL)) ;
Rabe, Klaus F. (Airway Research Center North (ARCN). Members of the Germany Center for Lung Research (DZL)) ;
Hansen, Gesine (Department of Pediatric Pneumology. Allergology and Neonatology. Hannover Medical School) ;
Kopp, Matthias V. (Department of Paediatric Respiratory Medicine. Inselspital. University Children's Hospital of Bern. University of Bern) ;
Rios, Raimon (Programa de Pós Graduação em Imunologia (PPGIm). Instituto de Ciências da Saúde. Universidade Federal da Bahia (UFBA)) ;
Cruz, Maria Jesús (Hospital Universitari Vall d'Hebron) ;
González-Barcala, Francisco Javier (Complejo Hospitalario Universitario de Santiago de Compostela. Servicio de Neumología) ;
Olaguibel, José María (Complejo Hospitalario de Navarra) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz. Instituto de Investigación Hospital Universitario La Paz. Servicio de Alergología) ;
Canino, Glorisa (Behavioral Sciences Research Institute. University of Puerto Rico) ;
Cloutier, Michelle (Department of Pediatrics. University of Connecticut) ;
Del Pozo, Victoria (Instituto de Investigación Sanitaria Hospital Universitario Fundación Jiménez Díaz. Servicio de Inmunología) ;
Rodriguez-Santana, Jose R. (Centro de Neumología Pediátrica) ;
Korta-Murua, Javier (Universidad del País Vasco. Departamento de Pediatría) ;
Villar, Jesús (Hospital Universitario de Gran Canaria Doctor Negrín. Multidisciplinary Organ Dysfunction Evaluation Research Network. Research Unit) ;
Potočnik, Uros (Laboratory for Biochemistry. Molecular Biology and Genomics. Faculty for Chemistry and Chemical Engineering. University of Maribor) ;
Figueiredo, Camila (Instituto de Ciências da Saúde. Universidade Federal da Bahia) ;
Kabesch, Michael (Department of Paediatric Pneumology and Allergy. University Children's Hospital Regensburg (KUNO)) ;
Mukhopadhyay, Somnath (Population Pharmacogenetics Group. Biomedical Research Institute. Ninewells Hospital and Medical School. University of Dundee) ;
Pirmohamed, Munir (Department of Pharmacology and Therapeutics. Institute of Systems. Molecular and Integrative Biology. University of Liverpool) ;
Hawcutt, Daniel (NIHR Alder Hey Clinical Research Facility. Alder Hey Children's Hospital) ;
Melén, Erik (Sachs' Children's Hospital. South General Hospital) ;
Palmer, Colin (Population Pharmacogenetics Group. Biomedical Research Institute. Ninewells Hospital and Medical School. University of Dundee) ;
Turner, Steve (Child Health. University of Aberdeen) ;
Maitland-van der Zee, Anke H. (Department of Paediatric Respiratory Medicine and Allergy. Emma's Children Hospital. Amsterdam UMC. University of Amsterdam) ;
von Mutius, Erika (Comprehensive Pneumology Center Munich (CPC-M). Member of the German Center for Lung Research) ;
Celedón, Juan C. (Division of Pediatric Pulmonary Medicine. UPMC Children's Hospital of Pittsburgh. University of Pittsburgh) ;
Brusselle, Guy (Department of Respiratory Medicine. Erasmus University Medical Center) ;
Chew, Fook Tim (Department of Biological Sciences. National University of Singapore) ;
Bleecker, Eugene (Division of Genetics. Genomics. and Precision Medicine. Department of Internal Medicine. University of Arizona College of Medicine) ;
Meyers, Deborah (Division of Genetics. Genomics. and Precision Medicine. Department of Internal Medicine. University of Arizona College of Medicine) ;
Burchard, Esteban G. (Department of Bioengineering and Therapeutic Sciences. University of California San Francisco) ;
Pino-Yanes, Maria (Universidad de la Laguna. Instituto de Tecnologías Biomédicas)
Background: Asthma exacerbations are a serious public health concern due to high healthcare resource utilization, work/school productivity loss, impact on quality of life, and risk of mortality. The genetic basis of asthma exacerbations has been studied in several populations, but no prior study has performed a multi-ancestry meta-analysis of genome-wide association studies (meta-GWAS) for this trait. [...]
2022 - 10.1111/pai.13802
Pediatric Allergy and Immunology, Vol. 33 Núm. 6 (june 2022) , p. e13802
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5.
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13 p, 486.2 KB |
"Acute kidney injury in critically ill patients with COVID-19 : The AKICOV multicenter study in Catalonia"
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De La Vega, A. (Hospital Universitari Vall d'Hebron) ;
Navas Pérez, Ana Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pérez-Carrasco, Marcos (Hospital Universitari Vall d'Hebron) ;
Sonet, María Torrens (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Buendia, Yolanda Diaz (Hospital del Mar (Barcelona, Catalunya)) ;
Ballujera, Patricia Ortiz (Hospital Universitari de Girona Doctor Josep Trueta) ;
López, Miguel Rodríguez (Hospital de Sant Joan Despí Moisès Broggi) ;
Sabater-Riera, Joan (Hospital Universitari de Bellvitge) ;
Olmo-Isasmendi, Aitor (Hospital Universitari General de Catalunya) ;
Torra, Ester Vendrell (Hospital General de Granollers) ;
García-Pumarino, María Álvarez (Consorci Sanitari de Terrassa Barcelona) ;
Villamayor, Mercedes Ibarz (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Catalán Ibars, Rosa María (Hospital Universitari de Vic) ;
Zelaya, Iban Oliva (Hospital Universitari Joan XXIII de Tarragona) ;
Chica, Javier Pardos (Hospital Universitario Arnau de Vilanova de Lleida) ;
Anglès, Conxita Rovira (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Tomasa-Irriguible, Teresa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Serra, Anna Baró (Parc Hospitalari Martí i Julià) ;
Casanova, Edward J. (Hospital Asepeyo Sant Cugat del Vallès) ;
González de Molina, Francisco Javier (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Universitat Autònoma de Barcelona
This study describes the incidence, evolution and prognosis of acute kidney injury (AKI) in critical COVID-19 during the first pandemic wave. We performed a prospective, observational, multicenter study of confirmed COVID-19 patients admitted to 19 intensive care units (ICUs) in Catalonia (Spain). [...]
2023 - 10.1371/journal.pone.0284248
PloS one, Vol. 18 (april 2023)
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6.
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9 p, 1.4 MB |
Treatment patterns of monoclonal antibodies in patients with severe uncontrolled asthma treated by pulmonologists in Spain
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Casas-Maldonado, Francisco (Hospital Universitario San Cecilio (Granada)) ;
Álvarez Gutiérrez, Francisco Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Blanco-Aparicio, Marina (Complejo Hospitalario Universitario de A Coruña) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cisneros, Carolina (Hospital Universitario de la Princesa (Madrid)) ;
Soto-Campos, Gregorio (Hospital Universitario de Jerez (Jerez de la Frontera)) ;
Román Bernal, Berta (Hospital Dr. José Molina Orosa, Lanzarote) ;
González-Barcala, Francisco Javier (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Universitat Autònoma de Barcelona
Introduction and objectives: The use of monoclonal antibody (mAb)-based therapies is becoming the new standard of care for severe uncontrolled asthma (SUA). Even though patients may qualify for one or more of these targeted treatments, based on different clinical criteria, a global vision of mAb prescription management in a large sample of hospitals is not well characterised in Spain. [...]
Introducción y objetivos: El uso de terapias basadas en anticuerpos monoclonales (mAb) se está convirtiendo en el nuevo estándar de atención para el asma grave no controlada (AGNC). A pesar de que los pacientes pueden optar a uno o varios de estos tratamientos dirigidos, con base en diferentes criterios clínicos, en España no se ha caracterizado bien una visión global de la gestión de la prescripción de mAb en una gran muestra de hospitales. [...]
Elsevier España, 2023 - 10.1016/j.opresp.2023.100252
Open Respiratory Archives, Vol. 5 Num. 3 (jul. 2023) , art. 100252
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7.
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27 p, 1.3 MB |
Documento de consenso de asma grave en adultos. Actualización 2022
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Alvarez Gutiérrez, Francisco Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Blanco-Aparicio, Marina (Complejo Hospitalario Universitario de A Coruña) ;
Casas-Maldonado, Francisco (Hospital Universitario San Cecilio (Granada)) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
González-Barcala, Francisco Javier (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Carretero-García, José Ángel (Servicio de Neumología. Hospital Royo Villanova) ;
Castilla-Martínez, Manuel (Servicio de Neumología. Hospital Universitario Los Arcos del Mar Menor) ;
Cisneros, Carolina (Servicio de Neumología. Hospital Universitario La Princesa. FIB La Princesa) ;
Diaz-Pérez, David (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Martínez-Moragon, Eva (Servicio de Neumología. Hospital Universitario Dr Peset) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Padilla, Alicia (Unidad de Asma. Hospital Costa del Sol) ;
Perpiñá-Tordera, Miguel (Hospital Universitari i Politècnic La Fe (València)) ;
Soto-Campos, Gregorio (Unidad de Gestión Clínica de Neumología y Alergia. Hospital Universitario de Jerez)
El asma grave constituye un síndrome heterogéneo con diversas variantes clínicas, y representa en muchas ocasiones una enfermedad compleja con necesidad de un abordaje especializado y multidisciplinar, así como la utilización de múltiples fármacos. [...]
Severe asthma is a heterogeneous syndrome with several clinical variants and often represents a complex disease requiring a specialized and multidisciplinary approach, as well as the use of multiple drugs. [...]
2022 - 10.1016/j.opresp.2022.100192
Open Respiratory Archives, Vol. 4 (2022) , p. 100192
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15 p, 935.7 KB |
Augmented renal clearance. An unnoticed relevant event
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Tomasa-Irriguible, Teresa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sabater-Riera, Joan (Hospital Universitari de Bellvitge) ;
Pérez-Carrasco, Marcos (Hospital Universitari Vall d'Hebron) ;
Ortiz-Ballujera, Patricia (Hospital Universitari de Girona Doctor Josep Trueta) ;
Díaz Buendia, Yolanda (Hospital del Mar (Barcelona, Catalunya)) ;
Navas Pérez, Ana Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Betbesé Roig, Antoni Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rodríguez-López, Miguel (Hospital de Sant Joan Despí Moisès Broggi) ;
Ibarz, Mercedes (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Olmo-Isasmendi, Aitor (Hospital Universitari General de Catalunya) ;
Oliva-Zelaya, Iban (Hospital Universitari Joan XXIII de Tarragona) ;
Rovira-Anglès, Conxita (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Cano Hernández, Silvia (Fundació Althaia (Manresa, Catalunya)) ;
Vendrell-Torra, Ester (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Catalan-Ibars, Rosa-María (Consorci Hospitalari de Vic) ;
Miralbés-Torner, Mar (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
González de Molina, Francisco Javier (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Xirgu-Cortacans, Judith (Hospital General de Granollers) ;
Marcos Neira, Pilar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Augmented renal clearance (ARC) is a phenomenon that can lead to a therapeutic failure of those drugs of renal clearance. The purpose of the study was to ascertain the prevalence of ARC in the critically ill patient, to study the glomerular filtration rate (GFR) throughout the follow-up and analyze the concordance between the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimation formula and measured GFR. [...]
2021 - 10.1177/00368504211018580
Science Progress, Vol. 104 Núm. 2 (2021)
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9.
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8 p, 731.6 KB |
COVID-19's impact on care practice for alpha-1-antitrypsin deficiency patients
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Calle Rubio, Myriam (Universidad Complutense de Madrid) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Michel de la Rosa, Francisco Javier (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Hernández Pérez, José María (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Montero Martínez, Carmen (Complejo Hospitalario Universitario de A Coruña) ;
Montoro Ronsano, José Bruno (Hospital Universitari Vall d'Hebron) ;
Casas-Maldonado, Francisco (Universidad de Granada) ;
Rodríguez Hermosa, Juan Luis (Universidad Complutense de Madrid) ;
Tabernero Huguet, Eva María (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Martínez Sesmero, José Manuel (Hospital Clínico San Carlos (Madrid)) ;
Martínez Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Callejas González, Francisco Javier (Hospital Complejo Universitario de Albacete) ;
Torres Durán, María (Hospital Álvaro Cunqueiro (Vigo)) ;
Universitat Autònoma de Barcelona
Patients with alpha-1 antitrypsin deficiency (AATD), commonly categorized as a rare disease, have been affected by the changes in healthcare management brought about by COVID-19. This study's aim was to identify the changes that have taken place in AATD patient care as a result of the COVID-19 pandemic in Spain and to propose experts' recommendations aimed at ensuring humanized and quality care for people with AATD in the post-pandemic situation. [...]
2023 - 10.1186/s12913-023-09094-3
BMC health services research, Vol. 23 (january 2023)
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10.
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14 p, 2.6 MB |
Analysis of Differentially Expressed MicroRNAs in Serum and Lung Tissues from Individuals with Severe Asthma Treated with Oral Glucocorticoids
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Gil-Martínez, Marta (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Lorente-Sorolla, Clara (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Rodrigo-Muñoz, José M. (Instituto de Salud Carlos III) ;
Lendínez, Miguel Ángel (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Núñez-Moreno, Gonzalo (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
de la Fuente, Lorena (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Mínguez, Pablo (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Mahíllo-Fernández, Ignacio (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Sastre, Joaquin (Hospital Universitario Fundación Jiménez Díaz) ;
Valverde-Monge, Marcela (Hospital Universitario Fundación Jiménez Díaz) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ;
Caballero, María L. (Hospital Universitario La Paz (Madrid)) ;
González-Barcala, Francisco J. (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Arismendi, Ebymar (Hospital Clínic i Provincial de Barcelona) ;
Bobolea, Irina (Hospital Clínic i Provincial de Barcelona) ;
Valero, Antonio (Hospital Clínic i Provincial de Barcelona) ;
Muñoz Gall, Xavier (Hospital Universitari Vall d'Hebron) ;
Cruz, María Jesús (Hospital Universitari Vall d'Hebron) ;
Martínez Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Plaza, Vicente (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Olaguibel, José M. (Complejo Hospitalario de Navarra) ;
Del Pozo, Victoria (Universidad Autónoma de Madrid) ;
Universitat Autònoma de Barcelona
Nowadays, microRNAs (miRNAs) are increasingly used as biomarkers due to their potential contribution to the diagnosis and targeted treatment of a range of diseases. The aim of the study was to analyze the miRNA expression profiles in serum and lung tissue from patients with severe asthma treated with oral corticosteroids (OCS) and those without OCS treatment. [...]
2023 - 10.3390/ijms24021611
International journal of molecular sciences, Vol. 24 (january 2023)
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