UAB Digital Repository of Documents 4 records found  Search took 0.00 seconds. 
1.
5 p, 190.8 KB In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction / Silva-Arrieta, Sandra (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Goulder, Phillip J.R. (Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America) ; Brander, Christian. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
2020 - 10.1371/journal.ppat.1008607
PLoS pathogens, Vol. 16 Núm. 6 (january 2020) , p. e1008607  
2.
0 p, 5.4 MB Antigen production after latency reversal and expression of inhibitory receptors in CD8+ T cells limit the killing of HIV-1 reactivated cells / Ruiz, A. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanch-Lombarte, Oscar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Jimenez-Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Peña, R. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Genescà Ferrer, Meritxell. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Goulder, P. (Department of Paediatrics. University of Oxford) ; Barnard, R. (Department of Infectious Disease. Merck and Co. Inc.) ; Howell, B. (Department of Infectious Disease. Merck and Co. Inc.) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
The so-called shock and kill therapies aim to combine HIV-1 reactivation by latency-reversing agents (LRA) with immune clearance to purge the HIV-1 reservoir. The clinical use of LRA has demonstrated detectable perturbations in the HIV-1 reservoir without measurable reductions to date. [...]
2019 - 10.3389/fimmu.2018.03162
Frontiers in immunology, Vol. 10 Núm. JAN (2019) , p. 3162  
3.
14 p, 2.0 MB Differential Immunodominance Hierarchy of CD8 + T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection / Adland, Emily ; Hill, Matilda ; Lavandier, Nora ; Csala, Anna ; Edwards, Anne ; Chen, Fabian ; Radkowski, Marek ; Kowalska, Justyna D. ; Paraskevis, Dimitrios ; Hatzakis, Angelos ; Valenzuela-Ponce, Humberto ; Pfafferott, Katja ; Williams, Ian ; Pellegrino, Pierre ; Borrow, Persephone ; Mori, Masahiko ; Rockstroh, Jürgen ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Tudor-Williams, Gareth ; Frater, John ; Stryhn, Anette ; Buus, Soren ; Teran, Gustavo Reyes ; Mallal, Simon ; John, Mina ; Buchbinder, Susan ; Kirk, Gregory ; Martin, Jeffrey ; Michael, Nelson ; Fellay, Jacques ; Deeks, Steve ; Walker, Bruce ; Avila-Rios, Santiago ; Cole, David ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrington, Mary ; Goulder, Philip ; Universitat Autònoma de Barcelona
The well-characterized association between HLA-B*27:05 and protection against HIV disease progression has been linked to immunodominant HLA-B*27:05-restricted CD8 + T-cell responses toward the conserved Gag KK10 (residues 263 to 272) and polymerase (Pol) KY9 (residues 901 to 909) epitopes. [...]
2018 - 10.1128/JVI.01685-17
Journal of Virology, Vol. 92 (january 2018)  
4.
26 p, 2.7 MB Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection / Adland, Emily (University of Oxford) ; Paioni, Paolo (University of Oxford) ; Thobakgale, Christina (University of KwaZulu-Natal (Durban, Sud-àfrica)) ; Laker, Leana (Kimberley Hospital (Northern Cape, Sud-àfrica)) ; Mori, Luisa (Kimberley Hospital (Northern Cape, Sud-àfrica)) ; Muenchhoff, Maximilian (University of Oxford) ; Csala, Anna (University of Oxford) ; Clapson, Margaret (Saint Hospital for Children (London, Gran Bretanya)) ; Flynn, Jacquie (Saint Hospital for Children (London, Gran Bretanya)) ; Novelli, Vas (Saint Hospital for Children (London, Gran Bretanya)) ; Hurst, Jacob (University of Oxford) ; Naidoo, Vanessa (University of KwaZulu-Natal (Durban, Sud-àfrica)) ; Shapiro, Roger (Botswana Harvard AIDS Institute Partnership (Gaborone, Botswana)) ; Gary, Kuan-Hsiang Huang (University of Oxford) ; Frater, John (University of Oxford) ; Prendergast, Andrew (Queen Mary University of London) ; Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ndung'u, Thumbi (University of KwaZulu-Natal (Durban, Sud-àfrica)) ; Walker, Bruce D. (University of Oxford) ; Carrington, Mary (National Cancer Institute (Maryland, Estats Units d'Amèrica)) ; Jooste, Pieter (Kimberley Hospital (Northern Cape, Sud-àfrica)) ; Goulder, Philip J. R. (University of Oxford)
Abstract. HLA class I polymorphism has a major influence on adult HIV disease progression. An important mechanism mediating this effect is the impact on viral replicative capacity (VRC) of the escape mutations selected in response to HLA-restricted CD8+ T-cell responses. [...]
2015 - 10.1371/journal.ppat.1004954
PLoS pathogens, Vol. 11 Núm. 6 (June 2015)  

See also: similar author names
1 Goulder, Philip
1 Goulder, Philip J. R.
1 Goulder, Philip J.R.
1 Goulder, Philip J.R.
1 Goulder, Phillip J.R.
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