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26 p, 5.3 MB Identification of tight-binding plasmepsin II and falcipain 2 inhibitors in aqueous extracts of marine invertebrates by the combination of enzymatic and interaction-based assays / Salas-Sarduy, Emir (Universidad de La Habana (La Havana, Cuba). Centro de Estudio de Proteínas) ; Guerra, Yasel (Universidad de La Habana (La Havana, Cuba). Centro de Estudio de Proteínas) ; Covaleda Cortés, Giovanny (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Avilés, Francesc X. (Francesc Xavier) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Chávez Planes, María A. (Universidad de La Habana (La Havana, Cuba). Centro de Estudio de Proteínas)
Natural products from marine origin constitute a very promising and underexplored source of interesting compounds for modern biotechnological and pharmaceutical industries. However, their evaluation is quite challenging and requires specifically designed assays to reliably identify the compounds of interest in a highly heterogeneous and interfering context. [...]
2017 - 10.3390/md15040123
Marine drugs, Vol. 15, Issue 4 (April 2017)  

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1 Guerra, Yves de Saá
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