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22 p, 620.6 KB Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines - Multi-country assessment / Weibel, Daniel (Erasmus Medical Center (Rotterdam, Països Baixos)) ; Sturkenboom, Miriam (University Utrecht Medical Center) ; Black, Steven (Cincinnati Children's Hospital, Cincinnati, OH, USA) ; de Ridder, Maria (Erasmus Medical Center (Rotterdam, Països Baixos)) ; Dodd, Caitlin (Erasmus Medical Center (Rotterdam, Països Baixos)) ; Bonhoeffer, Jan (Brighton Collaboration Foundation (Basilea, Suïssa)) ; Vanrolleghem, Ann (Erasmus Medical Center (Rotterdam, Països Baixos)) ; van der Maas, Nicoline (National Institute for Public Health and the Environment (Bilthoven, Països Baixos)) ; Lammers, Gert Jan (Sleep-Wake Center SEIN (Heemstede, Països Baixos)) ; Overeem, Sebastiaan (Sleep Medicine Centre Kempenhaeghe (Heeze, Països Baixos)) ; Gentile, Angela (Hospital de Niños Ricardo Gutiérrez (Buenos Aires, Argentina)) ; Giglio, Norberto (Hospital de Niños Ricardo Gutiérrez (Buenos Aires, Argentina)) ; Castellano, Vanesa (Hospital de Niños Ricardo Gutiérrez (Buenos Aires, Argentina)) ; Kwong, Jeffrey C. (Institute for Clinical Evaluative Sciences-ICES (Ontario, Canada)) ; Murray, Brian J. (University of Toronto) ; Cauch-Dudek, Karen (Institute for Clinical Evaluative Sciences-ICES (Ontario, Canada)) ; Juhasz, Diana (Institute for Clinical Evaluative Sciences-ICES (Ontario, Canada)) ; Campitelli, Michael (Institute for Clinical Evaluative Sciences-ICES (Ontario, Canada)) ; Datta, Alexandre N. (University Hospital Basel (Basilea, Suïssa)) ; Kallweit, Ulf (Witten/Herdecke University) ; Huang, Wan-Ting (Taiwan Centers for Disease Control) ; Huang, Yu-Shu (Chang Gung Memorial Hospital (Taiwan). Department of Child Psychiatry and Sleep Center) ; Hsu, Chung-Yao (Kaohsiung Medical University Hospital (Kaohsiung, Taiwan)) ; Chen, Hsi-Chung (National Taiwan University Hospital (Taipei, Taiwan)) ; Giner Soriano, Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Gaig, Carles (Hospital Clínic i Provincial de Barcelona) ; Tió, Ester (Althaia Xarxa Assistencial Universitària de Manresa (Manresa, Catalunya)) ; Perez-Vilar, Silvia (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat -FISABIO (València)) ; Diez-Domingo, Javier (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat -FISABIO (València)) ; Puertas, Francisco Javier (Hospital Universitari de la Ribera (València)) ; Svenson, Lawrence W. (University of Alberta (Alberta, Canada). Division of Preventive Medicine) ; Mahmud, Salaheddin M. (University of Manitoba (Manitoba, Canada). Rady Faculty of Health Sciences) ; Carleton, Bruce (University of British Columbia. Faculty of Medicine) ; Naus, Monika (University of British Columbia. Faculty of Medicine) ; Arnheim-Dahlström, Lisen (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Pedersen, Lars (Aarhus University (Aarhus, Dinamarca)) ; DeStefano, Frank (Centers for Disease Control and Prevention-CDC (Atlanta, Estats Units d'Amèrica)) ; Shimabukuro, Tom T. (Centers for Disease Control and Prevention-CDC (Atlanta, Estats Units d'Amèrica)) ; Universitat Autònoma de Barcelona
In 2010, a safety signal was detected for narcolepsy following vaccination with Pandemrix, an AS03-adjuvanted monovalent pandemic H1N1 influenza (pH1N1) vaccine. To further assess a possible association and inform policy on future use of adjuvants, we conducted a multi-country study of narcolepsy and adjuvanted pH1N1 vaccines. [...]
2018 - 10.1016/j.vaccine.2018.08.008
Vaccine, Vol. 36 (august 2018) , p. 6202-6211  

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