UAB Digital Repository of Documents 2 records found  Search took 0.02 seconds. 
1.
14 p, 2.2 MB Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats / Campos Martorell, Mireia (Vall d'Hebron Institut de Recerca) ; Cano Sarabia, Antonia María (Institut Català de Nanociència i Nanotecnologia) ; Simats, Alba (Vall d'Hebron Institut de Recerca) ; Hernández Guillamón, María del Mar (Vall d'Hebron Institut de Recerca) ; Rosell, Anna (Vall d'Hebron Institut de Recerca) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Montaner, Joan (Hospital Vall d'Hebron. Departament de Neurologia) ; Universitat Autònoma de Barcelona
Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into the brain. [...]
2016 - 10.2147/IJN.S107292
International Journal of Nanomedicine, Vol. 11 (June 2016) , p. 3035-3048  
2.
12 p, 5.7 MB Intracellular CXCR4 + cell targeting with T22-empowered protein-only nanoparticles / Unzueta Elorza, Ugutz (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Céspedes, María Virtudes (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Ferrer Miralles, Neus (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casanova, Isolda (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Cedano, Juan (Laboratory of Immunology, Regional Norte, Universidad de la Republica, Salto, Uruguay) ; Corchero, José Luis (CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona) ; Domingo-Espín, Joan (CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona) ; Villaverde, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mangues, Ramón (CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona) ; Vázquez Gómez, Esther (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Cell-targeting peptides or proteins are appealing tools in nanomedicine and innovative medicines because they increase the local drug concentration and reduce potential side effects. CXC chemokine receptor 4 (CXCR4) is a cell surface marker associated with several severe human pathologies, including colorectal cancer, for which intracellular targeting agents are currently missing. [...]
2012 - 10.2147/IJN.S34450
International Journal of Nanomedicine, Vol. 7 (august 2012) , p. 4533-4544  

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