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1.
11 p, 912.1 KB Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing / Corominas, Jordi (Radboud University Medical Center) ; Klein, Marieke (Radboud University Medical Center) ; Zayats, Tetyana (University of Bergen) ; Rivero, Olga (University of Würzburg) ; Ziegler, Georg C. (University of Würzburg) ; Pauper, Marc (Radboud University Medical Center) ; Neveling, Kornelia (Radboud University Medical Center) ; Poelmans, Geert (Radboud University Medical Center) ; Jansch, Charline (University of Würzburg) ; Svirin, Evgeniy (I.M. Sechenov First Moscow State Medical University) ; Geissler, Julia (University Hospital of Würzburg) ; Weber, Heike (University Hospital Frankfurt) ; Reif, Andreas (University Hospital Frankfurt) ; Arias Vasquez, Alejandro (Radboud University Medical Center) ; Galesloot, Tessel E. (Radboud University Medical Center) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ; Buitelaar, Jan K. (Radboud University Medical Center) ; Ramos Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Cormand, Bru (Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat) ; Ribasés, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hveem, Kristian (Norwegian University of Science and Technology) ; Gabrielsen, Maiken Elvestad (Norwegian University of Science and Technology) ; Hoffmann, Per (University of Basel) ; Cichon, Sven (University Hospital Basel) ; Haavik, Jan (Haukeland University Hospital) ; Johansson, Stefan (University of Bergen) ; Jacob, Christian P. (University of Würzburg) ; Romanos, Marcel (University Hospital of Würzburg) ; Franke, Barbara (Radboud University Medical Center) ; Lesch, Klaus-Peter (Maastricht University)
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with a complex genetic background, hampering identification of underlying genetic risk factors. We hypothesized that combining linkage analysis and whole-exome sequencing (WES) in multi-generation pedigrees with multiple affected individuals can point toward novel ADHD genes. [...]
2018 - 10.1038/s41380-018-0210-6
Molecular Psychiatry, Vol. 25 (august 2018) , p. 2047-2057  
2.
28 p, 2.6 MB ENIGMA and global neuroscience : A decade of large-scale studies of the brain in health and disease across more than 40 countries / Thompson, Paul M. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Jahanshad, Neda (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Ching, Christopher R. K. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Salminen, Lauren E. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Thomopoulos, Sophia I. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Bright, Joanna (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Baune, Bernhard T. (The University of Melbourne. The Florey Institute of Neuroscience and Mental Health) ; Bertolín, Sara (Bellvitge Biomedical Research Institute-IDIBELL. Department of Psychiatry, Bellvitge University Hospital) ; Bralten, Janita (Radboud University. Donders Institute for Brain, Cognition and Behaviour) ; Bruin, Willem B. (University of Amsterdam, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; Bülow, Robin (University Medicine Greifswald. Institute for Diagnostic Radiology and Neuroradiology) ; Chen, Jian (The Ohio State University. Department of Computer Science and Engineering) ; Chye, Yann (Monash University. Turner Institute for Brain and Mental Health, School of Psychological Sciences) ; Dannlowski, Udo (University of Münster. Department of Psychiatry) ; de Kovel, Carolien G. F. (Max Planck Institute for Psycholinguistics. Language & Genetics Department) ; Donohoe, Gary (National University of Ireland. The Center for Neuroimaging and Cognitive Genomics, School of Psychology) ; Eyler, Lisa T. (Desert-Pacific Mental Illness Research, Education, and Clinical Center, VA San Diego Healthcare System) ; Faraone, Stephen V. (SUNY Upstate Medical University. Departments of Psychiatry and of Neuroscience and Physiology) ; Favre, Pauline (NeuroSpin, UNIACT Lab, Psychiatry Team, CEA Saclay) ; Filippi, Courtney A. (National Institute of Mental Health, National of Health) ; Frodl, Thomas (German Center for Neurodegenerative Diseases (DZNE)) ; Garijo, Daniel (University of Southern California. Information Sciences Institute) ; Gil, Yolanda (University of Southern California. Department of Computer Science) ; Grabe, Hans J. (German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald) ; Grasby, Katrina L. (QIMR Berghofer Medical Research Institute. Psychiatric Genetics) ; Hajek, Tomas (National Institute of Mental Health) ; Han, Laura K. M. (Amsterdam University Medical Centers, VU University Medical Center, GGZ inGeest, Amsterdam Neuroscience. Department of Psychiatry) ; Hatton, Sean N. (University of Sydney. Brain and Mind Centre) ; Hilbert, Kevin (Humboldt-Universität zu Berlin. Department of Psychology) ; Ho, Tiffany C. (University of California, San Francisco. Department of Psychiatry & Weill Institute for Neurosciences) ; Holleran, Laurena (National University of Ireland. The Center for Neuroimaging and Cognitive Genomics, School of Psychology) ; Homuth, Georg (University Medicine Greifswald. Interfaculty Institute for Genetics and Functional Genomics) ; Hosten, Norbert (University Medicine Greifswald. Institute for Diagnostic Radiology and Neuroradiology) ; Houenou, Josselin (APHP, Mondor University Hospitals, School of Medicine, DMU Impact, Psychiatry Department) ; Ivanov, Iliyan (Icahn School of Medicine at Mount Sinai) ; Jia, Tianye (King's College London. Centre for Population Neuroscience and Precision Medicine (PONS), MRC SGDP Centre, Institute of Psychiatry, Psychology & Neuroscience) ; Kelly, Sinead (Brigham and Women's Hospital. Department of Psychiatry) ; Klein, Marieke (Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands) ; Kwon, Jun Soo (Seoul National University College of Natural Sciences. Department of Brain and Cognitive Sciences) ; Laansma, Max A. (Location VUmc, Amsterdam Neuroscience. Department of Anatomy & Neurosciences, Amsterdam UMC) ; Leerssen, Jeanne (Netherlands Institute for Neuroscience. Department of Sleep and Cognition) ; Lueken, Ulrike (Humboldt-Universität zu Berlin. Department of Psychology) ; Nunes, Abraham (Dalhousie University. Faculty of Computer Science) ; Neill, Joseph O' (University of California, Los Angeles. Child & Adolescent Psychiatry) ; Opel, Nils (University of Münster. Department of Psychiatry) ; Piras, Fabrizio (Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation) ; Piras, Federica (Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation) ; Postema, Merel C. (Max Planck Institute for Psycholinguistics. Language & Genetics Department) ; Pozzi, Elena (Orygen, The National Centre of Excellence in Youth Mental Health) ; Shatokhina, Natalia (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Department of Psychobiology and Methodology in Health Sciences) ; Spalletta, Gianfranco (Baylor College of Medicine. Department of Psychiatry and Behavioral Sciences) ; Sun, Daqiang (Veterans Affairs Greater Los Angeles Healthcare System. Department of Mental Health) ; Teumer, Alexander (University Medicine Greifswald. Institute for Community Medicine) ; Tilot, Amanda K. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Tozzi, Leonardo (Stanford University. Department of Psychiatry & Behavioral Sciences) ; van der Merwe, Celia (Massachusetts General Hospital. Analytic and Translational Genetics Unit) ; Van Someren, Eus J. W. (VU University, Amsterdam UMC. Psychiatry and Integrative Neurophysiology) ; van Wingen, Guido A. (University of Amsterdam, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; Völzke, Henry (German Centre for Cardiovascular Research, Partner Site Greifswald) ; Walton, Esther (University of Bath. Department of Psychology) ; Wang, Lei (Radiology, Northwestern University Feinberg School of Medicine) ; Winkler, Anderson M. (National Institute of Mental Health, National of Health) ; Wittfeld, Katharina (German Center for Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald) ; Wright, Margaret J. (University of Queensland. Centre for Advanced Imaging) ; Yun, Je-Yeon (Seoul National University College of Medicine. Yeongeon Student Support Center) ; Zhang, Guohao (Department of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, MD USA) ; Zhang-James, Yanli (SUNY Upstate Medical University. Department of Psychiatry and Behavioral Sciences) ; Adhikari, Bhim M. (University of Maryland School of Medicine. Department of Psychiatry) ; Agartz, Ingrid (Diakonhjemmet Hospital. Department of Psychiatric Research) ; Aghajani, Moji (Department of Research & Innovation, GGZ InGeest) ; Aleman, André (University of Groningen, University Medical Center Groningen) ; Althoff, Robert R. (University of Vermont. Psychiatry, Pediatrics, and Psychological Sciences) ; Altmann, Andre (University College London. Centre for Medical Image Computing (CMIC), Department of Medical Physics and Biomedical Engineering) ; Andreassen, Ole A. (Oslo University Hospital. Division of Mental Health and Addiction) ; Baron, David A. (Western University of Health Sciences. Provost and Senior Vice President) ; Bartnik-Olson, Brenda L. (Loma Linda University Medical Center. Department of Radiology) ; Marie Bas-Hoogendam, Janna (Leiden Institute for Brain and Cognition, Leiden, The Netherlands) ; Baskin-Sommers, Arielle R. (Yale University. Department of Psychology) ; Bearden, Carrie E. (University of California. Department of Psychology) ; Berner, Laura A. (Icahn School of Medicine at Mount Sinai) ; Boedhoe, Premika S. W. (Location VUmc, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; Brouwer, Rachel M. (Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands) ; Buitelaar, Jan K. (Radboud University Medical Center. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour) ; Caeyenberghs, Karen (Deakin University. Cognitive Neuroscience Unit, School of Psychology) ; Cecil, Charlotte A. M. (Erasmus Medical Centre. Department of Epidemiology) ; Cohen, Ronald A. (Clinical and Health Psychology, Gainesville, FL USA) ; Cole, James H. (University College London. Dementia Research Centre, Institute of Neurology) ; Conrod, Patricia J. (Universite de Montreal, Centre de Recherche CHU Ste-Justine, Montreal, QC Canada) ; De Brito, Stephane A. (University of Birmingham. School of Psychology and Centre for Human Brain Health) ; de Zwarte, Sonja M. C. (Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands) ; Dennis, Emily L. (Harvard Medical School. Psychiatry Neuroimaging Laboratory, Brigham & Women's Hospital) ; Desrivieres, Sylvane (King's College London. Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience) ; Dima, Danai (King's College London. Department of Neuroimaging, Institute of Psychology, Psychiatry and Neurosciences) ; Ehrlich, Stefan (TU Dresden. Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine) ; Esopenko, Carrie (School of Health Professions, Rutgers Biomedical Health Sciences. Department of Rehabilitation and Movement Sciences) ; Fairchild, Graeme (University of Bath. Department of Psychology) ; Fisher, Simon E. (Max Planck Institute for Psycholinguistics. Language & Genetics Department) ; Fouche, Jean-Paul (University of Stellenbosch. SU/UCT MRC Unit on Risk & Resilience in Mental Disorders) ; Francks, Clyde (Max Planck Institute for Psycholinguistics. Language & Genetics Department) ; Frangou, Sophia (University of British Columbia) ; Franke, Barbara (Radboud University Medical Center. Department of Psychiatry) ; Garavan, Hugh P. (University of Vermont. Department of Psychiatry) ; Glahn, David C. (Institute of Living. Olin Neuropsychiatric Research Center) ; Groenewold, Nynke A. (University of Cape Town. Department of Psychiatry and Mental Health) ; Gurholt, Tiril P. (Oslo University Hospital. Division of Mental Health and Addiction) ; Gutman, Boris A. (Institute for Information Transmission Problems, Kharkevich Institute) ; Hahn, Tim (University of Münster. Department of Psychiatry) ; Harding, Ian H. (Monash University. Turner Institute for Brain and Mental Health & School of Psychological Sciences) ; Hernaus, Dennis (Maastricht University. Department of Psychiatry & Neuropsychology, School for Mental Health and Neuroscience) ; Hibar, Derrek P. (Genentech, Inc) ; Hillary, Frank G. (Social Life and Engineering Sciences Imaging Center, University Park, PA USA) ; Hoogman, Martine (Radboud University. Donders Institute for Brain, Cognition and Behaviour) ; Hulshoff Pol, Hilleke E. (Department of Psychiatry, UMC Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands) ; Jalbrzikowski, Maria (University of Pittsburgh. Department of Psychiatry) ; Karkashadze, George A. (Research and Scientific Institute of Pediatrics and Child Health, CCH RAS, Ministry of Science and Higher Education, Moscow, Russian Federation) ; Klapwijk, Eduard T. (Leiden Institute for Brain and Cognition, Leiden, The Netherlands) ; Knickmeyer, Rebecca C. (University of North Carolina at Chapel Hill. Department of Psychiatry) ; Kochunov, Peter (University of Maryland School of Medicine. Department of Psychiatry) ; Koerte, Inga K. (Ludwig-Maximilians-Universität München. CBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy) ; Kong, Xiang-Zhen (Max Planck Institute for Psycholinguistics. Language & Genetics Department) ; Liew, Sook-Lei (Chan Division of Occupational Science and Occupational Therapy, Los Angeles, CA USA) ; Lin, Alexander P. (Harvard Medical School) ; Logue, Mark W. (Boston University School of Medicine. Biomedical Genetics) ; Luders, Eileen (University of Southern California. Laboratory of Neuro Imaging, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Macciardi, Fabio (University of California, Irvine. Department of Psychiatry and Human Behavior) ; Mackey, Scott (University of Vermont. Department of Psychiatry) ; Mayer, Andrew R. (Mind Research Network) ; McDonald, Carrie R. (Psychiatry, San Diego, CA USA) ; McMahon, Agnes B. (The Kavli Foundation) ; Medland, Sarah E. (QIMR Berghofer Medical Research Institute. Psychiatric Genetics) ; Modinos, Gemma (King's College London. Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience) ; Morey, Rajendra A. (Mental Illness Research Education and Clinical Center, Durham VA Medical Center) ; Mueller, Sven C. (University of Deusto. Department of Personality, Psychological Assessment and Treatment) ; Mukherjee, Pratik (Radiology and Biomedical Imaging, San Francisco, CA USA) ; Namazova-Baranova, Leyla (Russian National Research Medical University MoH RF. Department of Pediatrics) ; Nir, Talia M. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Olsen, Alexander (Trondheim University Hospital. Department of Physical Medicine and Rehabilitation, St. Olavs Hospital) ; Paschou, Peristera (Purdue University. Biological Sciences) ; Pine, Daniel S. (National Institute of Mental Health Intramural Research Program) ; Pizzagalli, Fabrizio (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Rentería, Miguel E. (QIMR Berghofer Medical Research Institute. Department of Genetics and Computational Biology) ; Rohrer, Jonathan D. (UCL Queen Square Institute of Neurology. Department of Neurodegenerative Disease) ; Sämann, Philipp G. (Max Planck Institute of Psychiatry) ; Schmaal, Lianne (The University of Melbourne. Centre for Youth Mental Health) ; Schumann, Gunter (Charite, Humboldt University. Department of Psychiatry and Psychotherapy) ; Shiroishi, Mark S. (University of Southern California. Department of Radiology, Keck School of Medicine of USC) ; Sisodiya, Sanjay M. (Chalfont Centre for Epilepsy) ; Smit, Dirk J. A. (University of Amsterdam, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; Sønderby, Ida E. (Oslo University Hospital. Department of Medical Genetics) ; Stein, Dan J. (Department of Psychiatry & Neuroscience Institute, SA MRC Unit on Risk & Resilience in Mental Disorders, Cape Town, South Africa) ; Stein, Jason L. (University of North Carolina at Chapel Hill. Department of Genetics & UNC Neuroscience Center) ; Tahmasian, Masoud (Shahid Beheshti University. Institute of Medical Science and Technology) ; Tate, David F. (Missouri Institute of Mental Health) ; Turner, Jessica A. (Georgia State University. Psychology Department & Neuroscience Institute) ; van den Heuvel, Odile A. (Location VUmc, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; van der Wee, Nic J. A. (Leiden Institute for Brain and Cognition, Leiden, The Netherlands) ; van der Werf, Ysbrand D. (Location VUmc, Amsterdam Neuroscience. Department of Anatomy & Neurosciences, Amsterdam UMC) ; van Erp, Theo G. M. (University of California, Irvine. Center for the Neurobiology of Learning and Memory) ; van Haren, Neeltje E. M. (Erasmus Medical Centre. Department of Child and Adolescent Psychiatry/Psychology) ; van Rooij, Daan (Radboud University Medical Centre. Donders Centre for Cognitive Neuroimaging) ; van Velzen, Laura S. (The University of Melbourne. Centre for Youth Mental Health) ; Veer, Ilya M. (Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany) ; Veltman, Dick J. (Location VUmc, Amsterdam Neuroscience. Department of Psychiatry, Amsterdam UMC) ; Villalon-Reina, Julio E. (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ; Walter, Henrik (Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany) ; Whelan, Christopher D. (Research and Early Development, Biogen Inc) ; Wilde, Elisabeth A. (Baylor College of Medicine. Department of Physical Medicine and Rehabilitation) ; Zarei, Mojtaba (Shahid Beheshti University. Institute of Medical Science and Technology) ; Zelman, Vladimir (Skolkovo Institute of Science and Technology)
This review summarizes the last decade of work by the ENIGMA (nhancing euromaging enetics through eta nalysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. [...]
2020 - 10.1038/s41398-020-0705-1
Translational psychiatry, Vol. 10 (march 2020)  

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