|
53.
|
|
12 p, 371.6 KB |
DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
/
Osorio, Ana (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Milne, Roger L. (Cancer Epidemiology Centre (Melbourne, Austràlia)) ;
Kuchenbaecker, Karoline (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Vaclová, Tereza (Centro Nacional de Investigaciones Oncológicas) ;
Pita, Guillermo (Centro Nacional de Investigaciones Oncológicas) ;
Alonso, Rosario (Centro Nacional de Investigaciones Oncológicas) ;
Peterlongo, Paolo (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy) ;
Blanco Guillermo, Ignacio (Institut Català d'Oncologia) ;
De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Durán, Mercedes (Universidad de Valladolid) ;
Diez, Orland (Vall d'Hebron Institut d'Oncologia) ;
Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Konstantopoulou, Irene (Molecular Diagnostics Laboratory IRRP, National Centre for Scientific Research Demokritos Aghia Paraskevi Attikis, Athens, Greece) ;
Martínez-Bouzas, Cristina (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Andrés Conejero, Raquel (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Soucy, Penny (Centre Hospitalier Universitaire de Québec. Cancer Genomics Laboratory) ;
McGuffog, Lesley (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Barrowdale, Daniel (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Lee, Andrew (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
SWE-BRCA, None (Department of Oncology, Lund University, Lund, Sweden) ;
Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Loman, Niklas (Department of Oncology, Lund University Hospital, Lund, Sweden) ;
Ehrencrona, Hans (Department of Clinical Genetics, Lund University Hospital, Lund, Sweden) ;
Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois, United States of America) ;
Beattie, Mary S. (Departments of Medicine, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America) ;
Domchek, Susan M. (Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America) ;
Nathanson, Katherine (Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America) ;
Rebbeck, Timothy R. (Abramson Cancer Center and Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ;
Arun, Banu K. (University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America) ;
Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Walsh, Christine (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, United States of America) ;
Whittemore, Alice S. (Department of Health Research & Policy, Stanford University School of Medicine, Stanford, California, United States of America) ;
Daly, Mary B. (Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America) ;
Southey, Melissa (Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia) ;
Hopper, John L (Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Victoria, Australia) ;
Terry, Mary Beth (Department of Epidemiology, Columbia University, New York, New York, United States of America) ;
Buys, Saundra (Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America) ;
Janavicius, Ramunas (Vilnius University Hospital Santariskiu Clinics) ;
Dorfling, Cecilia M. (Department of Genetics, University of Pretoria, Pretoria, South Africa) ;
van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria, Pretoria, South Africa) ;
Steele, Linda (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ;
Neuhausen, Susan L. (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ;
Ding, Yuan Chun (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica). Department of Population Sciences) ;
Hansen, Thomas v. O. (Copenhagen University Hospital Rigshospitalet) ;
Jønson, Lars (Copenhagen University Hospital Rigshospitalet) ;
Ejlertsen, Bent (Copenhagen University Hospital Rigshospitalet) ;
Gerdes, Anne-Marie (Copenhagen University Hospital Rigshospitalet) ;
Infante, Mar (Universidad de Valladolid) ;
Herráez, Belén (Centro Nacional de Investigaciones Oncológicas) ;
Moreno, Leticia Thais (Centro Nacional de Investigaciones Oncológicas) ;
Weitzel, Jeffrey N. (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ;
Herzog, Josef (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ;
Weeman, Kisa (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ;
Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ;
Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ;
Zaffaroni, Daniela (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ;
Scuvera, Giulietta (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ;
Bonanni, Bernardo (Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy) ;
Mariette, Frederique (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare and Cogentech Cancer Genetic Test Laboratory, Milan, Italy) ;
Volorio, Sara (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare and Cogentech Cancer Genetic Test Laboratory, Milan, Italy) ;
Viel, Alessandra (Division of Experimental Oncology 1, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy) ;
Varesco, Liliana (Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy) ;
Papi, Laura (Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy) ;
Ottini, Laura (Department of Molecular Medicine, "Sapienza" University, Rome, Italy) ;
Tibiletti, Maria Grazia (UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria, Varese, Italy) ;
Radice, Paolo (Unit of Molecular bases of genetic risk and genetic testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ;
Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory IRRP, National Centre for Scientific Research Demokritos Aghia Paraskevi Attikis, Athens, Greece) ;
Garber, Judy (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Ellis, Steve (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Frost, Debra (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Platte, Radka (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Fineberg, Elena (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Evans, Gareth (Manchester Academic Health Sciences Centre) ;
Lalloo, Fiona (Manchester Academic Health Sciences Centre) ;
Izatt, Louise (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Eeles, Ros (Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, United Kingdom) ;
Adlard, Julian (Yorkshire Regional Genetics Service, Leeds, United Kingdom) ;
Davidson, Rosemarie (Ferguson-Smith Centre for Clinical Genetics (Glasgow, Regne Unit)) ;
Cole, Trevor (Birmingham Women's Hospital) ;
Eccles, Diana M (Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, United Kingdom) ;
Cook, Jackie (Sheffield Children's Hospital (Sheffield, Regne Unit)) ;
Hodgson, Shirley (Clinical Genetics Department, St Georges Hospital, University of London, London, United Kingdom) ;
Brewer, Carole (Royal Devon & Exeter Hospital (Exeter, Regne Unit)) ;
Tischkowitz, Marc (Addenbrookes Hospital (Cambridge, Regne Unit)) ;
Douglas, Fiona (Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom) ;
Porteous, Mary (South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom) ;
Side, Lucy (Great Ormond Street Hospital for Children (Londres)) ;
Walker, Lisa (Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom) ;
Morrison, Patrick (Northern Ireland Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom) ;
Donaldson, Alan (South West Regional Genetics Service, Bristol, United Kingdom) ;
Kennedy, John (Trinity College Dublin) ;
Foo, Claire (Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom) ;
Godwin, Andrew K. (Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America) ;
Schmutzler, Rita Katharina (University Hospital of Cologne (Colònia, Alemanya). Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO)) ;
Wappenschmidt, Barbara (University Hospital of Cologne (Colònia, Alemanya). Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO)) ;
Rhiem, Kerstin (University Hospital of Cologne (Colònia, Alemanya). Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO)) ;
Engel, Christoph (Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany) ;
Meindl, Alfons (Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany) ;
Ditsch, Nina (Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany) ;
Arnold, Norbert (Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany) ;
Plendl, Hans Jörg (Institute of Human Genetics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany) ;
Niederacher, Dieter (University Hospital of Düsseldorf (Alemanya)) ;
Sutter, Christian (Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany) ;
Wang-Gohrke, Shan (University Hospital of Ulm (Alemanya)) ;
Steinemann, Doris (Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany) ;
Preisler-Adams, Sabine (Institute of Human Genetics, University of Münster, Münster, Germany) ;
Kast, Karin (Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany) ;
Varon-Mateeva, Raymonda (Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany) ;
Gehrig, Andrea (Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany) ;
Stoppa-Lyonnet, Dominique (Université Paris Descartes, Sorbonne Paris Cité, Paris, France) ;
Sinilnikova, Olga M. (Centre National de la Recherche Scientifique (França)) ;
Mazoyer, Sylvie (Centre National de la Recherche Scientifique (França)) ;
Damiola, Francesca (Centre National de la Recherche Scientifique (França)) ;
Poppe, Bruce (Center for Medical Genetics, Ghent University, Ghent, Belgium) ;
Claes, Kathleen (Center for Medical Genetics, Ghent University, Ghent, Belgium) ;
Piedmonte, Marion (Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York, United States of America) ;
Tucker, Kathy (Prince of Wales Hospital (Australia)) ;
Backes, Floor (Ohio State University, Columbus Cancer Council, Columbus, Ohio, United States of America) ;
Rodríguez, Gustavo (Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois, United States of America) ;
Brewster, Wendy (Division of Gynecologic Oncology, NorthShore University HealthSystem, Chicago, Illinois, United States of America) ;
Wakeley, Katie (For Tufts Medical Center, Boston, Massachusetts, United States of America) ;
Rutherford, Thomas (Yale University School of Medicine, New Haven, Connecticut, United States of America) ;
Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland) ;
Aittomäki, Kristiina (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland) ;
Rookus, Matti A. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
van Os, Theo A. M. (Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands) ;
van der Kolk, Lizet (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
de Lange, J. L. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Meijers-Heijboer, Hanne E. J. (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos)) ;
van der Hout, A. H. (University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands) ;
van Asperen, Christi J. (Department of Clinical Genetics, Leiden University Medical Center Leiden, Leiden, The Netherlands) ;
Gómez Garcia, Encarna B. (Department of Clinical Genetics and GROW, School for Oncology and Developmental Biology, MUMC, Maastricht, The Netherlands) ;
Hoogerbrugge, Nicoline (Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands) ;
Collée, J. Margriet (Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands) ;
van Deurzen, Carolien H. M. (Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands) ;
van der Luijt, Rob B. (Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands) ;
Devilee, Peter (Department of Human Genetics & Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands) ;
HEBON, None (The Hereditary Breast and Ovarian Cancer Research Group, Netherlands Cancer Institute, Amsterdam, The Netherlands) ;
Olah, Edith (Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary) ;
Lázaro, Conxi (Institut d'Investigació Biomèdica de Bellvitge) ;
Teulé, Alex (Institut d'Investigació Biomèdica de Bellvitge) ;
Menéndez, Mireia (Institut d'Investigació Biomèdica de Bellvitge) ;
Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Cybulski, Cezary (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Gronwald, Jacek (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Durda, Katarzyna (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ;
Jaworska-Bieniek, Katarzyna (Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland) ;
Johannsson, Oskar Th. (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Maugard, Christine (Laboratoire de Diagnostic Génétique et Service d'Onco-hématologie, Hopitaux Universitaire de Strasbourg, CHRU Nouvel Hôpital Civil, Strasbourg, France) ;
Montagna, Marco (Veneto Institute of Oncology (Pàdua, Itàlia)) ;
Tognazzo, Silvia (Veneto Institute of Oncology (Pàdua, Itàlia)) ;
Teixeira, Manuel R. (Department of Genetics, Portuguese Oncology Institute, Porto, and Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal) ;
Healey, Sue (Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia) ;
Investigators, kConFab (Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Peter MacCallum Cancer Center, Melbourne, Australia) ;
Olswold, Curtis (Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America) ;
Guidugli, Lucia (Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America) ;
Lindor, Noralane (Center for Individualized Medicine, Mayo Clinic, Scottsdale, Arizona, United States of America) ;
Slager, Susan (Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America) ;
Szabo, Csilla I. (Center for Translational Cancer Research, Department of Biological Sciences, University of Delaware, Newark, Delaware, United States of America) ;
Vijai, Joseph (Memorial Sloan Kettering Cancer Center) ;
Robson, Mark (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ;
Kauff, Noah (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ;
Zhang, Liying (Diagnostic Molecular Genetics Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ;
Rau-Murthy, Rohini (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ;
Fink-Retter, Anneliese (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Singer, Christian F. (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Rappaport, Christine (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Geschwantler Kaulich, Daphne (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Pfeiler, Georg (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Tea, Muy-Kheng (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Berger, Andreas (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ;
Phelan, Catherine M. (Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, United States of America) ;
Greene, Mark H. (National Cancer Institute (Rockville, Estats Units d'Amèrica)) ;
Mai, Phuong L. (National Cancer Institute (Rockville, Estats Units d'Amèrica)) ;
Lejbkowicz, Flavio (Clalit National Israeli Cancer Control Center, Haifa, Israel) ;
Andrulis, Irene L. (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, and Cancer Care Ontario, Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada) ;
Mulligan, Anna Marie (University of Toronto) ;
Glendon, Gord (Mount Sinai Hospital (Toronto, Canadà)) ;
Toland, Amanda Ewart (Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America) ;
Bojesen, Anders (Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark) ;
Pedersen, Inge Sokilde (Aalborg University Hospital (Dinamarca)) ;
Sunde, Lone (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Thomassen, Mads (Odense University Hospital (Dinamarca)) ;
Kruse, Torben A. (Odense University Hospital (Dinamarca)) ;
Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Friedman, Eitan (Sheba Medical Center, Tel Aviv, Israel) ;
Laitman, Yael (Sheba Medical Center, Tel Aviv, Israel) ;
Shimon, Shani Paluch (Sheba Medical Center, Tel Aviv, Israel) ;
Simard, Jacques (Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Canada) ;
Easton, Douglas F. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Offit, Kenneth (Memorial Sloan Kettering Cancer Center) ;
Couch, Fergus J. (Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America) ;
Chenevix-Trench, Georgia (Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia) ;
Antoniou, Antonis C. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Benitez, Javier (Centro Nacional de Investigaciones Oncológicas) ;
Universitat Autònoma de Barcelona
Single Nucleotide Polymorphisms (SNPs) in genes involved in the DNA Base Excision Repair (BER) pathway could be associated with cancer risk in carriers of mutations in the high-penetrance susceptibility genes BRCA1 and BRCA2, given the relation of synthetic lethality that exists between one of the components of the BER pathway, PARP1 (poly ADP ribose polymerase), and both BRCA1 and BRCA2. [...]
2014 -  10.1371/journal.pgen.1004256
PLoS Genetics, Vol. 10 (april 2014)
|
|
guest ::
email alert
or subscribe to the 
RSS feed.
