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8 p, 814.9 KB Anti-MDA5 Antibodies in a Large Mediterranean Population of Adults with Dermatomyositis / Labrador Horrillo, Moises (Universitat Autonoma de Barcelona. Departament de Medicina) ; Martinez, Maria Angeles (Institut d'Investigació Biomèdica Sant Pau) ; Selva O'Callaghan, Albert (Universitat Autonoma de Barcelona. Departament de Medicina) ; Trallero Araguás, Ernesto (Universitat Autonoma de Barcelona. Departament de Medicina) ; Balada, Eva (Universitat Autonoma de Barcelona. Departament de Medicina) ; Vilardell Tarrés, Miquel (Universitat Autonoma de Barcelona. Departament de Medicina) ; Juárez, Cándido (Institut d'Investigació Biomèdica Sant Pau)
A new myositis-specific autoantibody directed against melanoma differentiation-associated gene 5 (anti-MDA5) has been described in patients with dermatomyositis (DM). We report the clinical characteristics of patients with anti-MDA5 in a large Mediterranean cohort of DM patients from a single center, and analyze the feasibility of detecting this autoantibody in patient sera using new assays with commercially available recombinant MDA5. [...]
2014 - 10.1155/2014/290797
Journal of Immunology Research, Vol. 2014 (february 2014)  

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