UAB Digital Repository of Documents 46 records found  beginprevious21 - 30nextend  jump to record: Search took 0.02 seconds. 
21.
4 p, 129.2 KB Bacterial cell factories for recombinant protein production; expanding the catalogue / Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
2013 - 10.1186/1475-2859-12-113
Microbial cell factories, Vol. 12, N. 113 (November 2013), p. 1-4  
22.
8 p, 557.8 KB Microbial factories for recombinant pharmaceuticals / Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Domingo i Espín, Joan (Universitat Autònoma de Barcelona. Department de Genètica i de Microbiologia) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Most of the hosts used to produce the 151 recombinant pharmaceuticals so far approved for human use by the Food and Drug Administration (FDA) and/or by the European Medicines Agency (EMEA) are microbial cells, either bacteria or yeast. [...]
2009 - 10.1186/1475-2859-8-17
Microbial cell factories, Vol. 8, N. 17 (March 2009) , p. 1-8
2 documents
23.
9 p, 1.8 MB Isolation of cell-free bacterial inclusion bodies / Rodríguez-Carmona, Escarlata (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cano Garrido, Olivia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Seras Franzoso, Joaquin (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; García Fruitós, Elena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Background: Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes. [...]
2010 - 10.1186/1475-2859-9-71
Microbial cell factories, Vol. 9, N. 71 (September 2010) , p. 1-9  
24.
10 p, 638.7 KB Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions / Carnicer Heras, Marc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Ten Pierick, Angela (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; van Dam, Jan (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Heijnen, Joseph J. (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; van Gulik, Walter (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química)
Background: Environmental and intrinsic stress factors can result in the global alteration of yeast physiology, as evidenced by several transcriptional studies. Hypoxia has been shown to have a beneficial effect on the expression of recombinant proteins in Pichia pastoris growing on glucose. [...]
2012 - 10.1186/1475-2859-11-83
Microbial cell factories, Vol. 11, N. 83 (June 2012) , p. 1-10
4 documents
25.
14 p, 772.5 KB Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose : methanol mixtures / Jordà Murria, Joel (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Jouhten, Paula (VTT Technical Research Centre of Finland (Espoo, Finlàndia)) ; Cámara Rey, Elena (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Maaheimo, Hannu (VTT Technical Research Centre of Finland (Espoo, Finlàndia)) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química)
Background: The methylotrophic yeast Pichia pastoris has emerged as one of the most promising yeast hosts for the production of heterologous proteins. Mixed feeds of methanol and a multicarbon source instead of methanol as sole carbon source have been shown to improve product productivities and alleviate metabolic burden derived from protein production. [...]
2012 - 10.1186/1475-2859-11-57
Microbial cell factories, Vol. 11, N. 57 (May 2012) , p. 1-14
5 documents
26.
3 p, 181.6 KB Inclusion bodies : a new concept : Commentary / García Fruitós, Elena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
In the last decades, the understanding of inclusion body biology and consequently, of their properties and potential biotechnological applications have dramatically changed. Therefore, the development of new purification protocols aimed to preserve those properties is becoming a pushing demand.
2010 - 10.1186/1475-2859-9-80
Microbial cell factories, Vol. 9, N. 8 (November 2010) , p. 1-3  
27.
2 p, 149.4 KB Old bugs for new tasks; the microbial offer in the proteomics era / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
2002 - 10.1186/1475-2859-1-4
Microbial cell factories, Vol. 1, N. 4 (October 2002) , p. 1-2  
28.
1 p, 134.7 KB A new editorial board for a new editorial period : editorial / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
2004 - 10.1186/1475-2859-3-3
Microbial cell factories, Vol. 3, N. 3 (April 2004) , p. 1-1  
29.
8 p, 340.2 KB Sequence determinants of protein aggregation : tools to increase protein solubility / Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Escherichia coli is one of the most widely used hosts for the production of recombinant proteins. However, very often the target protein accumulates into insoluble aggregates in a misfolded and biologically inactive form. [...]
2005 - 10.1186/1475-2859-4-11
Microbial cell factories, Vol. 4, N. 11 (April 2005) , p. 1-8  
30.
1 p, 134.1 KB Focusing in bioproduction science : editorial / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
As in other Biotechnological fields, the microbial production of recombinant proteins and other biomolecules can be approached from multiple angles through the help of diverse technologies of increasing complexity. [...]
2005 - 10.1186/1475-2859-4-10
Microbial cell factories, Vol. 4, N. 10 (April 2005) , p. 1-1  

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