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10 p, 2.1 MB |
Gibberellin A Metabolism Contributes to the Control of Photoperiod-Mediated Tuberization in Potato
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Bou Torrent, Jordi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Martínez-García, Jaime F. (Institució Catalana de Recerca i Estudis Avançats) ;
García-Martínez, José Luis (Instituto de Biologia Molecular y Celular de Plantas (València, Espanya)) ;
Prat, Salomé (Centro Nacional de Biotecología-CSIC)
Some potato species require a short-day (SD) photoperiod for tuberization, a process that is negatively affected by gibberellins (GAs). Here we report the isolation of StGA3ox2, a gene encoding a GA 3-oxidase, whose expression is increased in the aerial parts and is repressed in the stolons after transfer of photoperiod-dependent potato plants to SD conditions. [...]
2011 -  10.1371/journal.pone.0024458
PloS one, Vol. 6 (september 2011)
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108 p, 4.1 MB |
Attractor dynamics in perceptual decision making : from theoretical predictions to psychophysical experiments
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Prat-Ortega, Genís ;
de la Rocha, Jaime, dir. ;
Roxin, Alex, dir. ;
Alarcón Cor, Tomás, dir. ;
Universitat Autònoma de Barcelona.
Departament de Matemàtiques
De tant en tant, els humans i els animals en general hem de respondre a certs estímuls, que poden ser ambigus. Fa uns anys, abans que s'introduís el videoarbitratge (VAR; video assistant referee), els àrbitres de futbol no ho tenien fàcil. [...]
From time to time humans and animals must respond to a certain stimulus that can be ambiguous. In the old days, before the creation of video assistant referee, football referees had a very hard life. [...]
2019
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26 p, 1.8 MB |
Molecular and Clinicopathologic Characterization of Intravenous Leiomyomatosis
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Ordulu, Zehra (Massachusetts General Hospital (Boston)) ;
Chai, Hongyan (Department of Genetics, Yale University School of Medicine; New Haven, CT) ;
Peng, Gang (Department of Biostatistics, Yale School of Public Health, New Haven, CT) ;
McDonald, Anna G. (Department of Pathology, Wake Forest Baptist Medical Center, Winston Salem, NC) ;
De Nictolis, Michele (Department of Pathology, San Salvatore Hospital, Pesaro, Italy) ;
Garcia-Fernandez, Eugenia (Hospital Universitario La Paz (Madrid)) ;
Hardisson, David (Hospital Universitario La Paz (Madrid)) ;
Prat, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Li, Peining (Department of Genetics, Yale University School of Medicine; New Haven, CT) ;
Hui, Pei (Department of Pathology, Yale University School of Medicine; New Haven, CT) ;
Oliva, Esther (Massachusetts General Hospital (Boston)) ;
Buza, Natalia (Department of Pathology, Yale University School of Medicine; New Haven, CT)
Intravenous leiomyomatosis (IVL) is an unusual uterine smooth muscle proliferation that can be associated with aggressive clinical behavior despite a histologically benign appearance. It has some overlapping molecular characteristics with both uterine leiomyoma and leiomyosarcoma based on limited genetic data. [...]
2020 - 10.1038/s41379-020-0546-8
Modern Pathology, Vol. 33 (april 2020) , p. 1844-1860
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10 p, 1.9 MB |
Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer
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Codony-Servat, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cuatrecasas, Miriam ;
Asensio, Elena (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Montironi, Carla (Hospital Clínic i Provincial de Barcelona) ;
Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marín Aguilera, Mercedes (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Horndler, Carlos (Hospital Universitario Miguel Servet (Saragossa)) ;
Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rubini, Michele (Department of Experimental and Diagnostic Medicine, University of Ferrara) ;
Jares, Pedro (Hospital Clínic i Provincial de Barcelona) ;
Reig, Oscar (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Victoria, Iván (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gaba, Lydia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martín Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Alonso, Vicente (Hospital Universitario Miguel Servet (Saragossa)) ;
Escudero, Pilar (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Fernández-Martos, Carlos (Fundació Institut Valencià d'Oncologia) ;
Feliu, Jaime (Centro de Investigación Biomédica en Red de Cáncer) ;
Méndez, Jose Carlos (Centro Oncológico de Galicia) ;
Méndez, Miguel (Hospital Universitario de Móstoles (Madrid)) ;
Gallego, Javier (Hospital General Universitario de Elche) ;
Salud, Antonieta (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Rojo, Federico (Fundacion Jimenez Diaz) ;
Castells, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Prat, Aleix (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rosell, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-Albéniz, Xabier (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Camps, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Maurel, Joan (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
Although chemotherapy is the cornerstone treatment for patients with metastatic colorectal cancer (mCRC), acquired chemoresistance is common and constitutes the main reason for treatment failure. Monoclonal antibodies against insulin-like growth factor-1 receptor (IGF-1R) have been tested in pre-treated mCRC patients, but results have been largely deceiving. [...]
2017 - 10.1038/bjc.2017.279
British Journal of Cancer, Vol. 117 (november 2017) , p. 1777-1786
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12 p, 3.2 MB |
Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type
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Karnezis, Anthony N. (University of British Columbia. Department of Pathology and Laboratory Medicine) ;
Wang, Yemin (University of British Columbia. Department of Pathology and Laboratory Medicine) ;
Ramos, Pilar (Translational Genomics Research Institute) ;
Hendricks, William P. D. (Translational Genomics Research Institute) ;
Oliva, Esther (Massachusetts General Hospital (Boston)) ;
D'Angelo, Emanuela (Institut d'Investigació Biomèdica Sant Pau) ;
Prat, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Nucci, Marisa R. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Nielsen, Torsten O. (University of British Columbia. Department of Pathology and Laboratory Medicine) ;
Chow, Christine (University of British Columbia. Genetic Pathology Evaluation Centre) ;
Leung, Samuel (University of British Columbia. Genetic Pathology Evaluation Centre) ;
Kommoss, Friedrich (Synlab MVZ Pathologie) ;
Kommoss, Stefan (University Hospital of Tübingen (Alemanya)) ;
Silva, Annacarolina (Harvard Medical School. The James Homer Wright Pathology Laboratories) ;
Ronnett, Brigitte M. (The Johns Hopkins Hospital. Department of Pathology) ;
Rabban, Joseph T. (University of California San Francisco. Department of Anatomic Pathology) ;
Bowtell, David D. (Peter MacCallum Cancer Centre) ;
Weissman, Bernard E. (University of North Carolina. Department of Pathology and Laboratory Medicine) ;
Trent, Jeffrey M. (Translational Genomics Research Institute) ;
Gilks, C. Blake (University of British Columbia. Department of Pathology and Laboratory Medicine) ;
Huntsman, David G. (University of British Columbia. Department of Pathology and Laboratory Medicine) ;
Universitat Autònoma de Barcelona
Small cell carcinoma of the ovary, hypercalcaemic type () is a lethal and sometimes familial ovarian tumour of young women and children. We and others recently discovered that over 90% of harbour inactivating mutations in the chromatin remodelling gene with concomitant loss of its encoded protein (), one of two mutually exclusive of the / chromatin remodelling complex. [...]
2015 - 10.1002/path.4633
The Journal of Pathology, Vol. 238, Issue 3 (december 2015) , p. 389-400
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2 p, 631.8 KB |
Tumors transicionals d'ovari : l'important rau en la diferència
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Cuatrecasas, Miriam (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Prat, Jaime (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
El càncer d'ovari és el sisè més comú en dones després del càncer de pell, i encara a dia d'avui les causes no s'han determinat amb precisió. De tota manera, ara per ara ocupa el cinquè lloc com a causa de mort en dones, la qual cosa es tradueix en una preocupació general i en la voluntat d'implementar la investigació científica actual. [...]
El cáncer de ovario es el sexto más común en mujeres después del cáncer de piel, y todavía a día de hoy las causas no se han determinado con precisión. De todos modos, hoy por hoy ocupa el quinto lugar como causa de muerte en mujeres, lo que se traduce en una preocupación general y en la voluntad de implementar la investigación científica actual. [...]
2009
UAB divulga, Juliol 2009, p. 1-2
2 documents
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