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9 p, 241.0 KB |
Surviving rectal cancer at the cost of a colostomy : global survey of long-term health-related quality of life in 10 countries
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Kristensen, Helle Ø ;
Thyø, Anne ;
Emmertsen, Katrine J ;
Smart, Neil J ;
Pinkney, Thomas ;
Warwick, Andrea M ;
Pang, Dong ;
Elfeki, Hossam ;
Shalaby, Mostafa ;
Emile, Sameh H ;
Abdelkhalek, Mohamed ;
Zuhdy, Mohammad ;
Poskus, Tomas ;
Dulskas, Audrius ;
Horesh, Nir ;
Furnée, Edgar J B ;
Verkuijl, Sanne J ;
Rama, Nuno José ;
Domingos, Hugo ;
Maciel, João ;
Solis-Peña, Alejandro (Hospital Universitari Vall d'Hebron) ;
Espin-Basany, Eloy (Hospital Universitari Vall d'Hebron) ;
Hidalgo-Pujol, Marta (Hospital Universitari de Bellvitge) ;
Biondo, Sebastiano (Hospital Universitari de Bellvitge) ;
Sjövall, Annika ;
Christensen, Peter ;
Universitat Autònoma de Barcelona
Colorectal cancer management may require an ostomy formation; however, a stoma may negatively impact health-related quality of life (HRQoL). This study aimed to compare generic and stoma-specific HRQoL in patients with a permanent colostomy after rectal cancer across different countries. [...]
2022 -  10.1093/bjsopen/zrac085
BJS Open, Vol. 6 (december 2022)
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2.
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11 p, 2.6 MB |
Knock-Out of CmNAC-NOR Affects Melon Climacteric Fruit Ripening
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Liu, Bin (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Fruit ripening is an important process that affects fruit quality. A QTL in melon, ETHQV6. 3, involved in climacteric ripening regulation, has been found to be encoded by CmNAC-NOR, a homologue of the tomato NOR gene. [...]
2022 - 10.3389/fpls.2022.878037
Frontiers in plant science, Vol. 13 (June 2022) , art. 878037
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3.
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18 p, 5.2 MB |
Fruit morphology and ripening-related QTLs in a newly developed introgression line collection of the elite varieties 'Védrantais' and 'Piel de Sapo'
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Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica)
Melon is an economically important crop with widely diverse fruit morphology and ripening characteristics. Its diploid sequenced genome and multiple genomic tools make this species suitable to study the genetic architecture of fruit traits. [...]
2022 - 10.3390/plants11223120
Plants, Vol. 11, issue 22 (Nov. 2022) , art. 3120
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4.
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13 p, 1.2 MB |
Modulating climacteric intensity in melon through QTL stacking
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Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Areco, Lorena (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Fruit ripening is one of the main processes affecting fruit quality and shelf life. In melon there are both climacteric and non-climacteric genotypes, making it a suitable species to study fruit ripening. [...]
2022 - 10.1093/hr/uhac131
Horticulture research, Vol. 9 (June 2022) , art. uhac131
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5.
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343 p, 9.0 MB |
Genetic dissection of ETHQV8.1, a QTL related with climacteric fruit ripening in melon
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Santo Domingo Martínez, Miguel ;
Garcia Mas, Jordi, dir. ;
Pujol Abajo, Marta, dir.
La maduració dels fruits es un procés essencial de les plantes cultivades, permetent la dispersió de les llavors. A més, té una importància econòmica deguda als seus efectes en la vida útil dels fruits i el malbaratament d'aliments. [...]
La maduración del fruto es un proceso esencial en las plantas de cultivo, ya que permite la dispersión de las semillas. Además tiene importancia económica debido a sus efectos en la vida útil de los frutos y el desperdicio de comida. [...]
Fruit ripening is an essential process in crop plants, as it allows seed dispersion. Also, it has an economic importance due to its effect in fruit shelf-life and food waste. In flesh fruits there are two types of ripening: climacteric, with a characteristic peak of ethylene at the onset of ripening, coupled to an increase in cellular respiration; and non-climacteric, without ethylene peak production nor increase in respiration during the process. [...]
2023
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6.
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25 p, 23.2 MB |
CRISPR/Cas9 gene editing uncovers the roles of CONSTITUTIVE TRIPLE RESPONSE 1 and REPRESSOR OF SILENCING 1 in melon fruit ripening and epigenetic regulation
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Giordano, Andrea (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Quadrana, Leandro (Institut de Biologie de l'Ecole Normale Supérieure) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Melon (Cucumis melo) has emerged as an alternative model to tomato for studying fruit ripening due to the coexistence of climacteric and non-climacteric varieties. Previous characterization of a major quantitative trait locus (QTL), ETHQV8. [...]
2022 - 10.1093/jxb/erac148
Journal of Experimental Botany, Vol. 73, Issue 12 (June 2022) , p. 4022-4033
2 documents
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7.
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18 p, 7.7 MB |
Genetic dissection of climacteric fruit ripening in a melon population segregating for ripening behavior
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Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Ruggieri, Valentino (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Phillips, Michael A. (University of Toronto. Department of Biology) ;
Zhao, Guangwei (Zhengzhou Fruit Research Institute) ;
Lian, Qun (Agricultural Genomics Institute at Shenzhen) ;
Xu, Yongyang (Zhengzhou Fruit Research Institute) ;
He, Yuhua (Zhengzhou Fruit Research Institute) ;
Huang, Sanwen (Agricultural Genomics Institute at Shenzhen) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Melon is as an alternative model to understand fruit ripening due to the coexistence of climacteric and non-climacteric varieties within the same species, allowing the study of the processes that regulate this complex trait with genetic approaches. [...]
2020 - 10.1038/s41438-020-00411-z
Horticulture research, Vol. 7 (November 2020) , art. 187
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8.
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13 p, 4.7 MB |
A novel introgression line collection to unravel the genetics of climacteric ripening and fruit quality in melon
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Pereira, Lara (Centre de Recerca en Agrigenòmica) ;
Santo Domingo, Miguel (Centre de Recerca en Agrigenòmica) ;
Argyris, Jason (Centre de Recerca en Agrigenòmica) ;
Mayobre, Carlos (Centre de Recerca en Agrigenòmica) ;
Valverde, Laura (Centre de Recerca en Agrigenòmica) ;
Martín-Hernández, Ana Montserrat (Centre de Recerca en Agrigenòmica) ;
Pujol Abajo, Marta (Centre de Recerca en Agrigenòmica) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica)
Introgression lines are valuable germplasm for scientists and breeders, since they ease genetic studies such as QTL interactions and positional cloning as well as the introduction of favorable alleles into elite varieties. [...]
2021 - 10.1038/s41598-021-90783-6
Scientific reports, Vol. 11 (May 2021) , art 11364
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9.
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11 p, 1.8 MB |
A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses
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Burgueño, Javier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Pujol Argemí, Marta (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Monroy, Xavier (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Roche, David (Universitat Internacional de Catalunya. Facultat de Ciències Econòmiques i Socials) ;
Varela, Maria Jose (Universidade de Santiago de Compostela) ;
Merlos, Manuel (Department of Pharmacology, Drug Discovery & Preclinical Development, ESTEVE) ;
Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Universitat Autònoma de Barcelona.
Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública
Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly known as functional selectivity or biased agonism. [...]
2017 - 10.1038/s41598-017-15258-z
Scientific reports, Vol. 7 (november 2017)
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10.
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157 p, 5.4 MB |
Resultados ponderales y metabólicos de la gastrectomía vertical en pacientes con obesidad mórbida y súper-obesidad
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Hidalgo Pujol, Marta ;
Armengol Carrasco, Manuel, dir. ;
Fort, José Manuel, dir. ;
Vilallonga Puy, Ramon, dir.
La tesi doctoral s'ha estructurat en tres treballs fruit de l'activitat investigadora en l'Unitat de Cirurgia Endocrina Bariàtrica i Metabòlica de l'Hospital Universitari Vall d'Hebron. Un primer treball analitza les complicacions peritoperatorias, complicacions tardanes i tassa de reintervenció de pacients intervinguts de gastrectomia vertical en funció de l'índex de massa corporal inicial. [...]
La tesis doctoral se ha estructurado en tres trabajos fruto de la actividad investigadora en el seno de la Unidad de Cirugía Endocrina Bariátrica y Metabólica del Hospital Universitari Vall d'Hebron. [...]
The doctoral thesis has been structured in three works as a result of the research activity within the Endocrine Bariatric and Metabolic Surgery Unit of the Vall d'Hebron University Hospital. A first study analyzes the peritoperative complications, late complications and reoperation rate of patients undergoing sleeve gastrectomy based on the initial body mass index. [...]
2020
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