UAB Digital Repository of Documents 8 records found  Search took 0.01 seconds. 
1.
7 p, 1.1 MB Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency / Marin-Bejar, Oskar (Institut d'Investigació Biomèdica de Bellvitge) ; Romero-Moya, Damia (Institut d'Investigació Biomèdica de Bellvitge) ; Rodriguez-Ubreva, Javier (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Distefano, Maximiliano (Hospital Sant Joan de Déu) ; Lessi, Francesca (Fondazione Pisana Per la Scienza ONLUS (FPS)) ; Aretini, Paolo (Fondazione Pisana Per la Scienza ONLUS (FPS)) ; Liquori, Alessandro (Instituto de Salud Carlos III) ; Castaño, Julio (Banc de Sang i Teixits) ; Kozyra, Emilia (University of Freiburg) ; Kotmayer, Lili (Semmelweis University. Budapest, Hungary) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Cervera, José (Hospital Universitari i Politècnic La Fe (València)) ; Rodriguez-Gallego, José Carlos (University of Las Palmas de Gran Canaria) ; Nomdedeu, Josep Francisco (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Murillo- Sanjuán, Laura (Vall d'Hebron Institut d'Oncologia) ; de Heredia, Cristina Díaz (Vall d'Hebron Institut d'Oncologia) ; Pérez-Martinez, Antonio (Universidad Autónoma de Madrid) ; López-Cadenas, Félix (Instituto Biosanitario de Salamanca (IBSAL)) ; Martínez-Laperche, Carolina (Hospital Gregorio Marañón. Instituto de Investigación Sanitaria) ; Dorado-Herrero, Nieves (Hospital Gregorio Marañón. Instituto de Investigación Sanitaria) ; Marco, Francisco M. (Institute for Health and Biomedical Research (ISABIAL)) ; Prósper, Felipe (Instituto de Salud Carlos III) ; Menendez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Valcárcel, David (Vall d'Hebron Institut d'Oncologia) ; Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bödör, Csaba (Semmelweis University. Budapest, Hungary) ; Bigas Salvans, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Catalá, Albert (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Wlodarski, Marcin W. (St. Jude Children's Research Hospital, Memphis, TN) ; Giorgetti, Alessandra (Institut d'Investigació Biomèdica de Bellvitge) ; Universitat Autònoma de Barcelona. Departament de Medicina
2023 - 10.3324/haematol.2022.282305
Haematologica, Vol. 108 Núm. 9 (september 2023) , p. 2551-2557  
2.
10 p, 1.4 MB The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies / Manry, Jérémy ; Bastard, Paul ; Gervais, Adrian ; Le Voyer, Tom ; Rosain, Jérémie ; Philippot, Quentin ; Michailidis, Eleftherios ; Hoffmann, Hans-Heinrich ; Eto, Shohei ; Garcia-Prat, Marina (Hospital Universitari Vall d'Hebron) ; Bizien, Lucy ; Parra-Martínez, Alba (Hospital Universitari Vall d'Hebron) ; Yang, Rui ; Haljasmägi, Liis ; Migaud, Mélanie ; Särekannu, Karita ; Maslovskaja, Julia ; de Prost, Nicolas ; Tandjaoui-Lambiotte, Yacine ; Luyt, Charles-Edouard ; Amador-Borrero, Blanca ; Gaudet, Alexandre ; Poissy, Julien ; Morel, Pascal ; Richard, Pascale ; Cognasse, Fabrice ; Troya, Jesús ; Trouillet-Assant, Sophie ; Belot, Alexandre ; Saker, Kahina ; Garçon, Pierre ; Rivière, Jacques G.. (Hospital Universitari Vall d'Hebron) ; Lagier, Jean-Christophe ; Gentile, Stéphanie ; Rosen, Lindsey B. ; Shaw, Elana ; Morio, Tomohiro ; Tanaka, Junko ; Dalmau, David ; Tharaux, Pierre-Louis ; Sene, Damien ; Stepanian, Alain ; Mégarbane, Bruno ; Triantafyllia, Vasiliki ; Fekkar, Arnaud ; Heath, James R. ; Franco, José Luis ; Anaya, Juan-Manuel ; Solé-Violán, Jordi ; Imberti, Luisa ; Biondi, Andrea ; Bonfanti, Paolo ; Castagnoli, Riccardo ; Delmonte, Ottavia M. ; Zhang, Yu ; Snow, Andrew ; Holland, Steven M. ; Biggs, Catherine M. ; Moncada-Vélez, Marcela ; Arias, Andrés Augusto ; Lorenzo, Lazaro ; Boucherit, Soraya ; Anglicheau, Dany ; Planas, Anna Maria ; Haerynck, Filomeen ; Duvlis, Sotirija ; Ozcelik, Tayfun ; Keles, Sevgi ; Bousfiha, Ahmed A. ; El Bakkouri, Jalila ; Ramirez-Santana, Carolina ; Paul, Stephane ; Pan-Hammarström, Qiang ; Hammarström, Lennart ; Dupont, Annabelle ; Kurolap, Alina ; Metz, Christine N. ; Aiuti, Alessandro ; Casari, Giorgio ; Lampasona, Vito ; Ciceri, Fabio ; Barreiros, Lucila A. ; Domínguez-Garrido, Elena ; Vidigal, Mateus ; Zatz, Mayana ; van de Beek, Diederik ; Sahanic, Sabina ; Tancevski, Ivan ; Stepanovskyy, Yurii ; Boyarchuk, Oksana ; Nukui, Yoko ; Tsumura, Miyuki ; Vidaur, Loreto ; Tangye, Stuart G. ; Burrel, Sonia ; Duffy, Darragh ; Quintana-Murci, Lluis ; Klocperk, Adam ; Kann, Nelli Y. ; Shcherbina, Anna ; Lau, Yu-Lung ; Leung, Daniel ; Coulongeat, Matthieu ; Marlet, Julien ; Koning, Rutger ; Reyes, Luis Felipe ; Chauvineau-Grenier, Angélique ; Venet, Fabienne ; Monneret, Guillaume ; Nussenzweig, Michel C. ; Arrestier, Romain ; Boudhabhay, Idris ; Baris-Feldman, Hagit ; Hagin, David ; Wauters, Joost ; Meyts, Isabelle ; Dyer, Adam H. ; Kennelly, Sean P. ; Bourke, Nollaig M. ; Halwani, Rabih ; Sharif-Askari, Fatemeh Saheb ; Dorgham, Karim ; Sallette, Jérôme ; Sedkaoui, Souad Mehlal ; AlKhater, Suzan ; Rigo Bonnin, Raül (Institut d'Investigació Biomèdica de Bellvitge) ; Morandeira, Francisco ; Roussel, Lucie ; Vinh, Donald C. ; Erikstrup, Christian ; Condino-Neto, Antonio ; Prando, Carolina ; Bondarenko, Anastasiia ; Spaan, András N. ; Gilardin, Laurent ; Fellay, Jacques ; Lyonnet, Stanislas ; Bilguvar, Kaya ; Lifton, Richard P. ; Mane, Shrikant ; Anderson, Mark S. ; Boisson, Bertrand ; Béziat, Vivien ; Zhang, Shen-Ying ; Andreakos, Evangelos ; Hermine, Olivier ; Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ; Peterson, Pärt ; Mogensen, Trine H. ; Rowen, Lee ; Mond, James ; Debette, Stéphanie ; De Lamballerie, Xavier ; Burdet, Charles ; Bouadma, Lila ; Zins, Marie ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ; Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ; Gorochov, Guy ; Solanich, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ; Susen, Sophie ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Raoult, Didier ; Vasse, Marc ; Gregersen, Peter K. ; Piemonti, Lorenzo ; Rodríguez-Gallego, Carlos ; Notarangelo, Luigi ; Su, Helen C. ; Kisand, Kai ; Okada, Satoshi ; Puel, Anne ; Jouanguy, Emmanuelle ; Rice, Charles M. ; Tiberghien, Pierre ; Zhang, Qian ; Casanova, Jean-Laurent ; Abel, Laurent ; Cobat, Aurélie ; Universitat Autònoma de Barcelona
There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. [...]
2022 - 10.1073/pnas.2200413119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 (may 2022)  
3.
25 p, 2.4 MB Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 / Matuozzo, Daniela (University Paris Cité) ; Talouarn, Estelle (University Paris Cité) ; Marchal, Astrid (University Paris Cité) ; Zhang, Peng (Rockefeller University) ; Manry, Jeremy (University Paris Cité) ; Seeleuthner, Yoann (University Paris Cité) ; Zhang, Yu (Laboratory of Clinical Immunology and Microbiology) ; Bolze, Alexandre (Helix) ; Chaldebas, Matthieu (The Rockefeller University) ; Milisavljevic, Baptiste (The Rockefeller University) ; Gervais, Adrian (University Paris Cité) ; Bastard, Paul (Necker Hospital for Sick Children) ; Asano, Takaki (The Rockefeller University) ; Bizien, Lucy (University Paris Cité) ; Barzaghi, Federica (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ; Abolhassani, Hassan (Children's Medical Center) ; Abou Tayoun, Ahmad (Mohammed Bin Rashid University of Medicine and Health Sciences) ; Aiuti, Alessandro (Vita-Salute San Raffaele University) ; Alavi Darazam, Ilad (Loghman Hakim Hospital) ; Allende, Luis M. (Hospital 12 de Octubre (Madrid)) ; Alonso-Arias, Rebeca (Hospital Universitario Central de Asturias) ; Arias, Andrés Augusto (University of Antioquia UdeA) ; Aytekin, Gokhan (Konya City Hospital) ; Bergman, Peter (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Bondesan, Simone (IRCSS San Raffaele Scientific Institute) ; Bryceson, Yenan (Karolinska Institutet (Estocolm, Suècia)) ; Bustos, Ingrid G. (Universidad de La Sabana) ; Cabrera-Marante, Oscar (Hospital Universitario La Paz (Madrid)) ; Carcel, Sheila (Instituto Maimónides de Investigación Biomédica de Córdoba) ; Carrera, Paola (IRCSS San Raffaele Scientific Institute) ; Casari, Giorgio (Vita-Salute San Raffaele University) ; Chaïbi, Khalil (Sorbonne University) ; Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Condino-Neto, Antonio (University of São Paulo) ; Covill, Laura E. (Karolinska Institutet (Estocolm, Suècia)) ; Delmonte, Ottavia M. (Laboratory of Clinical Immunology and Microbiology) ; El Zein, Loubna (Lebanese University) ; Flores, Carlos (Universidad Fernando Pessoa Canarias) ; Gregersen, Peter K. (Feinstein Institute for Medical Research) ; Gut, Marta (Institut de Ciència i Tecnologia de Barcelona. Institut de Recerca en Biomedicina) ; Haerynck, Filomeen (Jeffrey Modell Diagnosis and Research Centre) ; Halwani, Rabih (University of Sharjah) ; Hancerli, Selda (Istanbul University) ; Hammarström, Lennart (Karolinska Institutet (Estocolm, Suècia)) ; Hatipoğlu, Nevin (University of Health Sciences, Turkey) ; Karbuz, Adem (Dr. Cemil Tascioglu City Hospital, Turkey) ; Keles, Sevgi (Necmettin Erbakan University) ; Kyheng, Christèle (Hôpital Bicêtre) ; Leon-Lopez, Rafael (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ; Franco, Jose Luis (University of Antioquia UDEA) ; Mansouri, Davood (Shahid Beheshti University of Medical Sciences) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Metin Akcan, Ozge (Necmettin Erbakan University) ; Migeotte, Isabelle (Centre de Génétique Humaine de L'Université Libre de Bruxelles) ; Morange, Pierre-Emmanuel (Aix-Marseille University) ; Morelle, Guillaume (Hôpital Bicêtre) ; Martín-Nalda, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Novelli, Giuseppe (IRCCS Neuromed) ; Novelli, Antonio (Bambino Gesù Children Hospital) ; Ozcelik, Tayfun (Bilkent University) ; Palabiyik, Figen (University of Health Sciences, Turkey) ; Pan-Hammarström, Qiang (Karolinska Institutet (Estocolm, Suècia)) ; de Diego, Rebeca Pérez (Hospital Universitario La Paz (Madrid)) ; Planas-Serra, Laura (Institut d'Investigació Biomèdica de Bellvitge) ; Pleguezuelo, Daniel E. (Hospital 12 de Octubre (Madrid)) ; Prando, Carolina (Instituto de Pesquisa Pelé Pequeno Príncipe) ; Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ; Reyes, Luis Felipe (Universidad de La Sabana) ; Rivière, Jacques G. (Hospital Universitari Vall d'Hebron) ; Rodriguez-Gallego, Carlos (Universidad Fernando Pessoa Canarias) ; Rojas, Julian (University of Antioquia UDEA) ; Rovere-Querini, Patrizia (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ; Schlüter, Agatha (Institut d'Investigació Biomèdica de Bellvitge) ; Shahrooei, Mohammad (KU Leuven.) ; Sobh, Ali (Mansoura University Children's Hospital) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ; Tandjaoui-Lambiotte, Yacine (Avicenne Hospital) ; Tipu, Imran (University of Management and Technology) ; Tresoldi, Cristina (IRCCS Ospedale San Raffaele) ; Troya, Jesus (Hospital Universitario Infanta Leonor) ; van de Beek, Diederik (Amsterdam Neuroscience) ; Zatz, Mayana (University of São Paulo) ; Zawadzki, Pawel (Adam Mickiewicz University) ; Al-Muhsen, Saleh Zaid (King Saud University) ; Alosaimi, Mohammed Faraj (King Saud University) ; Alsohime, Fahad M. (King Saud University) ; Baris-Feldman, Hagit (Tel Aviv University) ; Butte, Manish J. (University of California Los Angeles) ; Constantinescu, Stefan N. (Oxford University) ; Cooper, Megan A. (Washington University in St. Louis) ; Dalgard, Clifton L. (Uniformed Services University of the Health Sciences) ; Fellay, Jacques (Lausanne University Hospital) ; Heath, James R. (Institute for Systems Biology) ; Lau, Yu-Lung (Queen Mary Hospital) ; Lifton, Richard P. (Yale School of Medicine) ; Maniatis, Tom (New York Genome Center) ; Mogensen, Trine H. (Aarhus University Hospital (Aarhus, Dinamarca)) ; von Bernuth, Horst (Charité - Universitätsmedizin Berlin) ; Lermine, Alban (Laboratoire de Biologie Médicale Multisites Seqoia) ; Vidaud, Michel (Laboratoire de Biologie Médicale Multisites Seqoia) ; Boland, Anne (Université Paris-Saclay) ; Deleuze, Jean-François (Université Paris-Saclay) ; Nussbaum, Robert (Invitae) ; Kahn-Kirby, Amanda (Invitae) ; Mentre, France (Hôpital Bichat) ; Tubiana, Sarah (Hôpital Bichat) ; Gorochov, Guy (CIMI-Paris) ; Tubach, Florence (Institut Pierre Louis d'Epidémiologie et de Santé Publique) ; Hausfater, Pierre (Sorbonne Université) ; Meyts, Isabelle (KU Leuven) ; Zhang, Shen-Ying (The Rockefeller University) ; Puel, Anne (The Rockefeller University) ; Notarangelo, Luigi (Laboratory of Host Defenses) ; Boisson-Dupuis, Stephanie (The Rockefeller University) ; Su, Helen C. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Boisson, Bertrand (The Rockefeller University) ; Jouanguy, Emmanuelle (The Rockefeller University) ; Casanova, Jean-Laurent (Howard Hughes Medical Institute) ; Zhang, Qian (The Rockefeller University) ; Abel, Laurent (The Rockefeller University) ; Cobat, Aurélie (The Rockefeller University) ; Universitat Autònoma de Barcelona
We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15-20% of cases of life-threatening COVID-19 in unvaccinated patients. [...]
2023 - 10.1186/s13073-023-01173-8
Genome Medicine, Vol. 15 (april 2023)  
4.
2 p, 407.8 KB Erratum to : 36th International Symposium on Intensive Care and Emergency Medicine / Bateman, Ryon M. (University of Western Ontario) ; Sharpe, Michael D. (University of Western Ontario) ; Jagger, Justin E. (University of Western Ontario) ; Ellis, Christopher G. (University of Western Ontario) ; Solé Violan, Jordi (Hospital Universitario de Gran Canaria Dr. Negrín) ; López-Rodríguez, Marta (Hospital Universitario de Gran Canaria Dr. Negrín) ; Herrera-Ramos, Estefanía (Hospital Universitario de Gran Canaria Dr. Negrín) ; Ruíz-Hernández, José Juan (Hospital Universitario de Gran Canaria Dr. Negrín) ; Borderías, Luis (Hospital General Universitario San Jorge (Osca, Aragó)) ; Horcajada, Juan Pablo (Hospital del Mar (Barcelona, Catalunya)) ; González-Quevedo, Nereida (Hospital Universitario de Gran Canaria Dr. Negrín) ; Rajas Naranjo, Olga (Hospital Universitario de la Princesa (Madrid)) ; Briones, M. (Hospital Clínic Universitari (València)) ; Rodríguez de Castro, Felipe (Hospital Universitario de Gran Canaria Dr. Negrín) ; Rodríguez Gallego, Carlos (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Esen, Figen (İstanbul Üniversitesi) ; Orhun, Günseli (İstanbul Üniversitesi) ; Ergin Ozcan, Perihan (İstanbul Üniversitesi) ; Senturk, Ercin (İstanbul Üniversitesi) ; Ugur Yilmaz, Canan (İstanbul Üniversitesi) ; Orhan, Nurcan (İstanbul Üniversitesi) ; Arican, Nadir (İstanbul Üniversitesi) ; Kaya, Mahir (İstanbul Üniversitesi) ; Kucukerden, Melike (İstanbul Üniversitesi) ; Giris, Murat (İstanbul Üniversitesi) ; Akcan, Uğur (İstanbul Üniversitesi) ; Bilgic Gazioglu, Sema (İstanbul Üniversitesi) ; Tuzun, Erdem (İstanbul Üniversitesi) ; Riff, Reut (Ben-Gurion University of the Negev) ; Naamani, Oshri (Ben-Gurion University of the Negev) ; Douvdevani, Amos (Soroka Medical Center) ; Takegawa, R. (Osaka University Graduate School of Medicine) ; Yoshida, H. (Osaka University Graduate School of Medicine) ; Hirose, T. (Osaka University Graduate School of Medicine) ; Yamamoto, N. (Osaka University Graduate School of Medicine) ; Hagiya, H. (Osaka University Graduate School of Medicine) ; Ojima, M. (Osaka University Graduate School of Medicine) ; Akeda, Y. (Osaka University Graduate School of Medicine) ; Tasaki, O. (Nagasaki University Graduate School of Biomedical Sciences) ; Tomono, K. (Osaka University Graduate School of Medicine) ; Shimazu, T. (Osaka University Graduate School of Medicine) ; Ono, S. (Tokyo Medical University Hachioji Medical Center) ; Kubo, T. (National Defense Medical College (Japó)) ; Suda, S. (Tokyo Medical University Hachioji Medical Center) ; Ueno, T. (Tokyo Medical University Hachioji Medical Center) ; Ikeda, T. (Tokyo Medical University Hachioji Medical Center) ; Hirose, T. (Osaka University Graduate School of Medicine) ; Ogura, H. (Osaka University Graduate School of Medicine) ; Takahashi, H. (Osaka University Graduate School of Medicine) ; Ojima, M. (Osaka University Graduate School of Medicine) ; Kang, J. (Osaka University Graduate School of Medicine) ; Nakamura, Y. (Osaka University Graduate School of Medicine) ; Kojima, T. (Osaka University Graduate School of Medicine) ; Shimazu, T. (Osaka University Graduate School of Medicine) ; Ikeda, T. (Tokyo medical university) ; Suda, S. (Tokyo medical university) ; Izutani, Y. (Tokyo medical university) ; Ueno, T. (Tokyo medical university) ; Ono, S. (Tokyo medical university) ; Taniguchi, T. (Kanazawa University) ; O., M. (Kanazawa University Hospital) ; Dinter, Christiane (ThermoFisher (Alemanya)) ; Lotz, J. (Institut für Klinische Chemie und Laboratoriumsmedizin (Alemanya)) ; Eilers, B. (MVZ Labor Limbach Gruppe (Alemanya)) ; Wissmann, C. (ThermoFisher, Hennigsdorf, Germany) ; Lott, R. (Institut für Klinische Chemie und Laboratoriumsmedizin (Alemanya)) ; Meili, M. M. (Kantonsspital Aarau (Suïssa)) ; Schuetz, P. S. (Kantonsspital Aarau (Suïssa)) ; Hawa, H. (King Faisal Specialist Hospital & Research Center (Aràbia Saudí)) ; Sharshir, M. (King Faisal Specialist Hospital & Research Center (Aràbia Saudí)) ; Aburageila, M. (King Faisal Specialist Hospital & Research Center (Aràbia Saudí)) ; Salahuddin, N. (King Faisal Specialist Hospital & Research Center (Aràbia Saudí)) ; Chantziara, V. (Saint Savvas Hospital) ; Georgiou, S. (Saint Savvas Hospital) ; Tsimogianni, A. (Saint Savvas Hospital) ; Alexandropoulos, P. (Saint Savvas Hospital) ; Vassi, A. (Saint Savvas Hospital) ; Lagiou, F. (Saint Savvas Hospital) ; Valta, M. (Saint Savvas Hospital) ; Micha, G. (Saint Savvas Hospital) ; Chinou, E. (Saint Savvas Hospital) ; Michaloudis, G. (Saint Savvas Hospital) ; Kodaira, A. (Tokyo Medical University) ; Ikeda, T. (Tokyo Medical University) ; Ono, S. (Tokyo Medical University) ; Ueno, T. (Tokyo Medical University) ; Suda, S. (Tokyo Medical University) ; Izutani, Y. (Tokyo Medical University) ; Imaizumi, H. (Tokyo Medical University) ; De la Torre-Prados, M. V. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Garcia-De la Torre, A. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Enguix-Armada, A. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Puerto-Morlan, A. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Perez-Valero, Vidal (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Garcia-Alcantara, A. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Bolton, N. (St Helens and Knowsley NHS Trust) ; Dudziak, J. (St Helens and Knowsley NHS Trust) ; Bonney, S. (St Helens and Knowsley NHS Trust) ; Tridente, A. (St Helens and Knowsley NHS Trust) ; Nee, P. (St Helens and Knowsley NHS Trust) ; Nicolaes, G. (Maastricht University, Maastricht) ; Wiewel, M. (Center for Experimental and Molecular medicine) ; Schultz, M. (Academic Medical Center) ; Wildhagen, K. (Maastricht University) ; Horn, J. (Academic Medical Center) ; Schrijver, R. (Maastricht University) ; Van der Poll, T. (Center for Experimental and Molecular medicine) ; Reutelingsperger, C. (Maastricht University) ; Pillai, S. (NISCHR Haemostasis Biomarker Research Unit) ; Davies, G. (NISCHR Haemostasis Biomarker Research Unit) ; Mills, G. (NISCHR Haemostasis Biomarker Research Unit) ; Aubrey, R. (NISCHR Haemostasis Biomarker Research Unit) ; Morris, K. (NISCHR Haemostasis Biomarker Research Unit) ; Williams, P. (NISCHR Haemostasis Biomarker Research Unit) ; Evans, P. (NISCHR Haemostasis Biomarker Research Unit) ; Gayat, E. G. (Hôpital Lariboisière) ; Struck, J. (Sphingotec) ; Cariou, A. (Hôpital Cochin) ; Deye, N. (Hôpital Lariboisière) ; Guidet, B. (Hôpital Saint-Antoine) ; Jabert, S. (CHRU de Montpellier) ; Launay, J. (Hôpital Lariboisière) ; Legrand, M. (Hôpital Saint-Louis) ; Léone, M. (AP-HM (França)) ; Resche-Rigon, M. (Hôpital Saint-Louis) ; Vicaut, E. (Hôpital Lariboisière) ; Vieillard-Baron, A. (Hôpital Ambroise Paré) ; Mebazaa, Alexandre (Hôpital Lariboisière) ; Arnold, R. (Christiana Care Health System) ; Capan, M. (Christiana Care Health System) ; Linder, A. (Skåne University Hospital (Suècia)) ; Akesson, P. (Skåne University Hospital (Suècia)) ; Popescu, M. (Carol Davila University of Medicine and Pharmacy) ; Tomescu, D. (Carol Davila University of Medicine and Pharmacy) ; Sprung, C. L. (Hadassah-Hebrew University Medical Center) ; Calderon Morales, R. (Hadassah-Hebrew University Medical Center) ; Munteanu, G. (Hadassah-Hebrew University Medical Center) ; Orenbuch-Harroch, E. (Hadassah-Hebrew University Medical Center) ; Levin, P. (Hadassah-Hebrew University Medical Center) ; Kasdan, H. (LeukoDx, Jerusalem) ; Reiter, A. (LeukoDx, Jerusalem) ; Volker, T. (LeukoDx, Jerusalem) ; Himmel, Y. (LeukoDx, Jerusalem) ; Cohen, Y. (LeukoDx, Jerusalem) ; Meissonnier, J. (LeukoDx, Jerusalem) ; Girard, L. (Abionic SA, Lausanne) ; Rebeaud, F. (Abionic SA, Lausanne) ; Herrmann, I. (Swiss Federal Laboratories) ; Delwarde, B. (Lyon 1 University) ; Peronnet, E. (Lyon 1 University) ; Cerrato, E. (Lyon 1 University) ; Venet, F. (Lyon 1 University) ; Lepape, A. (Lyon 1 University) ; Rimmelé, T. (Lyon 1 University) ; Monneret, G. (Lyon 1 University) ; Textoris, J. (Lyon 1 University) ; Beloborodova, N. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Moroz, V. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Osipov, A. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Bedova, A. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Sarshor, Y. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Pautova, A. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Sergeev, A. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Chernevskaya, E. (Negovsky V.A. Research Institute of General Reanimatology (Rússia)) ; Odermatt, J. (Kantonsspital Aarau) ; Bolliger, R. (Kantonsspital Aarau) ; Hersberger, L. (Kantonsspital Aarau) ; Ottiger, M. (Kantonsspital Aarau) ; Christ-Crain, M. (University Hospital Basel (Basilea, Suïssa)) ; Mueller, B. (Kantonsspital Aarau) ; Sharma, N. K. (UNIFESP (Brasil)) ; Tashima, A. K. (UNIFESP (Brasil)) ; Brunialti, M. K. (UNIFESP (Brasil)) ; Machado, F. R. (UNIFESP (Brasil)) ; Assuncao, M. (Albert Einstein Hospital (Brasil)) ; Rigato, O. (Sírio Libanês Hospital (Brasil)) ; Salomao, R. (UNIFESP (Brasil)) ; Cajander, S. C. (Faculty of Medicine and Health Örebro University) ; Rasmussen, G. (Faculty of Medicine and Health Örebro University) ; Tina, E. (Faculty of Medicine and Health Örebro University) ; Söderquist, B. (Faculty of Medicine and Health Örebro University) ; Källman, J. (Faculty of Medicine and Health Örebro University) ; Strålin, K. (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Lange, A. L. (Faculty of Medicine and Health) ; Sundén-Cullberg, J. S. (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Magnuson, A. M. (Faculty of Medicine and Health (Suïssa)) ; Hultgren, O. H. (Faculty of Medicine and Health (Suïssa)) ; Davies, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Pillai, S. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Mills, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Aubrey, R. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Morris, K. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Williams, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Evans, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Pillai, S. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Davies, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Mills, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Aubrey, R. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Morris, K. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Williams, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Evans, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Pillai, S. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Davies, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Mills, G. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Aubrey, R. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Morris, K. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Williams, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Evans, P. (NISCHR Haemostasis Biomarker Research Unit (Suïssa)) ; Van der Geest, P. (Erasmus Medical Center (Holanda)) ; Mohseni, M. (Erasmus Medical Center(Holanda)) ; Linssen, J. (University Witten/Herdecke) ; De Jonge, R. (Erasmus Medical Center (Holanda)) ; Duran, S. (Maasstad Ziekenhuis) ; Groeneveld, J. (Erasmus Medical Center (Holanda)) ; Miller, R. (Intermountain Healthcare (Estats Units d'Amèrica)) ; Lopansri, B. K. (Intermountain Healthcare (Estats Units d'Amèrica)) ; McHugh, L. C. (Immunexpress, (Estats Units d'Amèrica)) ; Seldon, A. (Immunexpress (Estats Units d'Amèrica)) ; Burke, J. P. (Intermountain Healthcare (Estats Units d'Amèrica)) ; Johnston, J. (Lewisham and Greenwich NHS Trust) ; Reece-Anthony, R. (Lewisham and Greenwich NHS Trust) ; Bond, A. (Lewisham and Greenwich NHS Trust) ; Molokhia, A. (Lewisham and Greenwich NHS Trust) ; Mcgrath, C. (Wirral trust (Regne Unit)) ; Nsutebu, E. (RLBUHT (Regne Unit)) ; Bank Pedersen, P. (Odense University Hospital (Dinamarca)) ; Pilsgaard Henriksen, D. (Odense University Hospital (Dinamarca)) ; Mikkelsen, S. (Odense University Hospital (Dinamarca)) ; Touborg Lassen, A. (Wirral trust (Regne Unit)) ; Tincu, R. (Bucharest Clinical Emergency Hospital) ; Cobilinschi, C. (Bucharest Clinical Emergency Hospital) ; Tomescu, D. (Fundeni Clinical Institute) ; Ghiorghiu, Z. (Bucharest Clinical Emergency Hospital) ; Macovei, R. (Bucharest Clinical Emergency Hospital) ; Wiewel, M. A. (Amsterdam Medical Center) ; Harmon, M. B. (Amsterdam Medical Center) ; Van Vught, L. A. (Amsterdam Medical Center) ; Scicluna, B. P. (Amsterdam Medical Center) ; Hoogendijk, A. J. (Amsterdam Medical Center) ; Horn, J. (Amsterdam Medical Center) ; Zwinderman, A. H. (Amsterdam Medical Center) ; Cremer, O. L. (University Medical Center Utrecht) ; Bonten, M. J. (University Medical Center Utrecht) ; Schultz, M. J. (Amsterdam Medical Center) ; Van der Poll, T. (Amsterdam Medical Center) ; Juffermans, N. P. (Amsterdam Medical Center) ; Wiersinga, W. J. (Amsterdam Medical Center) ; Eren, G. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Tekdos, Y. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Dogan, M. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Acicbe, O. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Kaya, E. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Hergunsel, O. (Bakirkoy Dr.Sadi Konuk Training and Research Hospital) ; Alsolamy, S. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Ghamdi, G. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Alswaidan, L. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh) ; Alharbi, S. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Alenezi, F. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Arabi, Y. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Heaton, J. (Lewisham and Greenwich NHS Trust) ; Boyce, A. (Lewisham and Greenwich NHS Trust) ; Nolan, L. (Lewisham and Greenwich NHS Trust) ; Johnston, J. (Lewisham and Greenwich NHS Trust) ; Dukoff-Gordon, A. (Lewisham and Greenwich NHS Trust) ; Dean, A. (Lewisham and Greenwich NHS Trust) ; Molokhia, A. (Lewisham and Greenwich NHS Trust) ; Mann Ben Yehudah, T. (Assaf Harofeh MC, Beer Yaakov) ; Fleischmann, C. (Jena University Hopital) ; Thomas-Rueddel, D. (Jena University Hopital) ; Haas, C. (Jena University Hopital) ; Dennler, U. (Jena University Hopital) ; Reinhart, Konrad (Jena University Hopital) ; Suntornlohanakul, O. (Prince of Songkla University) ; Khwannimit, B. (Division of Critical Care Medicine) ; Breckenridge, F. (Glasgow Royal Infirmary) ; Puxty, A. (Glasgow Royal Infirmary) ; Szturz, P. (University Hospital and Faculty of Medicine Ostrava University) ; Folwarzcny, P. (University Hospital and Faculty of Medicine Ostrava University) ; Svancara, J. (Institute of Biostatistics and analyses, Masaryk University) ; Kula, R. (University Hospital and Faculty of Medicine Ostrava University) ; Sevcik, P. (University Hospital and Faculty of Medicine Ostrava University) ; Caneva, L. (Università degli studi di Pavia, scuola di specialità: Anestesia e Rianimazione) ; Casazza, A. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Bellazzi, E. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Marra, S. (Università degli studi di Pavia) ; Pagani, L. (Università degli studi di Pavia) ; Vetere, M. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Vanzino, R. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Ciprandi, D. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Preda, R. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Boschi, R. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Carnevale, L. (UOC Anestesia e Rianimazione Ospedale Civile di Vigevano) ; Lopez, V. (Hospital O'horan, Mérida, Mexico) ; Aguilar Arzapalo, Mario Francisco (Hospital O'horan, Mérida, Mexico) ; Barradas, L. (Hospital O'horan) ; Escalante, A. (Hospital O'horan) ; Gongora, J. (Hospital O'horan) ; Cetina, M. (Hospital O'horan) ; Adamik, B. (Medical University (Polònia)) ; Jakubczyk, D. (Medical University (Polònia)) ; Kübler, A. (Medical University (Polònia)) ; Radford, A. (AKPA (EstatsUnits d'Amèrica)) ; Lee, T. (St. Paul's Hospital (Canadà)) ; Singer, J. (St. Paul's Hospital (Canadà)) ; Boyd, J. (St. Paul's Hospital (Canadà)) ; Fineberg, D. (AKPA (Estats Units d'Amèrica)) ; Williams, M. (AKPA (Estats Units d'Amèrica)) ; Russell, J. (St. Paul's Hospital (Canadà)) ; Scarlatescu, E. (Fundeni Clinical Institute) ; Tomescu, D. (Fundeni Clinical Institute) ; Droc, G. (Fundeni Clinical Institute) ; Arama, S. (University of Medicine and Pharmacy "Carol Davila") ; Müller, M. (Acedemisch Medisch Centrum) ; Straat, M. (Acedemisch Medisch Centrum) ; Zeerleder, S. S. (Acedemisch Medisch Centrum) ; Juffermans, N. P. (Acedemisch Medisch Centrum) ; Fuchs, C. F. (University Hospital of Greifswald) ; Scheer, C. S. (University Hospital of Greifswald) ; Wauschkuhn, S. W. (University Hospital of Greifswald) ; Vollmer, M. V. (University Hospital of Greifswald) ; Meissner, K. M. (University Hospital of Greifswald) ; Kuhn, S. K. (University Hospital of Greifswald) ; Hahnenkamp, K. H. (University Hospital of Greifswald) ; Rehberg, S. R. (University Hospital of Greifswald) ; Gründling, M. G. (University Hospital of Greifswald) ; Yamamoto, N. (Osaka University Graduate School of Medicine) ; Ojima, M. (Osaka University Graduate School of Medicine) ; Hamaguchi, S. (Osaka University Graduate School of Medicine) ; Hirose, T. (Osaka University Graduate School of Medicine) ; Akeda, Y. (Osaka University Graduate School of Medicine) ; Takegawa, R. (Osaka University Graduate School of Medicine) ; Tasaki, O. (Nagasaki University Graduate School of Biomedical Sciences) ; Shimazu, T. (Osaka University Graduate School of Medicine) ; Tomono, K. (Osaka University Graduate School of Medicine) ; Gómez-Sánchez, E. (Hospital Clínico Universitario de Valladolid) ; Heredia-Rodríguez, M. (Hospital Clínico Universitario de Valladolid) ; Álvarez-Fuente, E. (Hospital Clínico Universitario de Valladolid) ; Lorenzo-López, M. (Hospital Clínico Universitario de Valladolid) ; Gómez-Pesquera, E. (Hospital Clínico Universitario de Valladolid) ; Aragón-Camino, M. (Hospital Clínico Universitario de Valladolid) ; Liu-Zhu, P. (Hospital Clínico Universitario de Valladolid) ; Sánchez-López, A. (Hospital Clínico Universitario de Valladolid) ; Hernández-Lozano, A. (Hospital Clínico Universitario de Valladolid) ; Peláez-Jareño, M. T. (Hospital Clínico Universitario de Valladolid) ; Tamayo, E. (Hospital Clínico Universitario de Valladolid) ; Thomas-Rüddel, D. O. (Jena University Hospital) ; Fleischmann, C. (Jena University Hospital) ; Haas, C. (Jena University Hospital) ; Dennler, U. (Jena University Hospital) ; Reinhart, Konrad (Jena University Hospital) ; Adora, V. (Medica Superspecialty Hospital (Índia)) ; Kar, A. (Medica Superspecialty Hospital (Índia)) ; Chakraborty, A. (Medica Superspecialty Hospital (Índia)) ; Roy, S. (Medica Superspecialty Hospital (Índia)) ; Bandyopadhyay, A. (Medica Superspecialty Hospital (Índia)) ; Das, M. (Medica Superspecialty Hospital (Índia)) ; Mann Ben Yehudah, T. (Assaf Harofeh MC) ; BenYehudah, G. (Assaf Harofeh MC) ; Salim, M. (DMC (Estats Units d'Amèrica)) ; Kumar, N. (DMC (Estats Units d'Amèrica)) ; Arabi, L. (DMC (Estats Units d'Amèrica)) ; Burger, T. (DMC (Estats Units d'Amèrica)) ; Lephart, P. (DMC (Estats Units d'Amèrica)) ; Toth-martin, E. (Wayne State University) ; Valencia, C. (Scientific Institute of Public Health (Bèlgica)) ; Hammami, N. (Scientific Institute of Public Health (Bèlgica)) ; Blot, S. (Ghent University, Ghent) ; Vincent, J. L. (Erasme University (Bélgica)) ; Lambert, M. L. (Scientific Institute of Public Health (Bélgica)) ; Brunke, J. (QualityLabs Bt GmbH, Nuremberg) ; Riemann, T. (B.Braun Melsungen AG, Melsungen) ; Roschke, I. (Dr. Roschke medical marketing GmbH) ; Tincu, R. (Bucharest Clinical Emergency Hospital) ; Cobilinschi, C. (Bucharest Clinical Emergency Hospital) ; Tomescu, D. (Fundeni Clinical Institute) ; Ghiorghiu, Z. (Bucharest Clinical Emergency Hospital) ; Macovei, R. (Bucharest Clinical Emergency Hospital) ; Nimitvilai, S. (Nakhonpathom hospital) ; Jintanapramote, K. (Nakhonpathom hospital) ; Jarupongprapa, S. (Nakhonpathom hospital) ; Adukauskiene, D. (Lithuanian University of Health Sciences) ; Valanciene, D. (Lithuanian University of Health Sciences) ; Bose, G. (University Hospital North Midlands) ; Lostarakos, V. (University Hospital North Midlands) ; Carr, B. (University Hospital North Midlands) ; Khedher, S. (EPS Charles-Nicolle (Tuníssia)) ; Maaoui, A. (EPS Charles-Nicolle (Tuníssia)) ; Ezzamouri, A. (EPS Charles-Nicolle (Tuníssia)) ; Salem, M. (EPS Charles-Nicolle (Tuníssia)) ; Chen, J. (Dalin Tzu Chi Hospital) ; Cranendonk, D. R. (Academic Medical Center (Holanda)) ; Van Vught, L. A. (Academic Medical Center (Holanda)) ; Wiewel, M. A. (University of Amsterdam) ; Cremer, O. L. (University Medical Center Utrecht) ; Horn, J. (University of Amsterdam) ; Bonten, M. J. (University Medical Center Utrecht) ; Schultz, M. J. (University of Amsterdam) ; Van der Poll, T. (University of Amsterdam) ; Wiersinga, W. J. (University of Amsterdam) ; Day, M. (Glasgow Royal Infirmary) ; Penrice, G. (NHS Greater Glasgow and Clyde) ; Roy, K. (Health Protection Scotland) ; Robertson, P. (Glasgow Royal Infirmary) ; Godbole, G. (Public Health England) ; Jones, B. (Glasgow Royal Infirmary) ; Booth, M. (Glasgow Royal Infirmary) ; Donaldson, L. (Glasgow Royal Infirmary) ; Kawano, Y. (Fukuoka University Hospital) ; Ishikura, H. (Fukuoka University Hospital) ; Al-Dorzi, H. (King Saud bin Abdulaziz University for Health Sciences) ; Almutairi, M. (King Saud bin Abdulaziz University for Health Sciences) ; Alhamadi, B. (King Saud bin Abdulaziz University for Health Sciences) ; Crizaldo Toledo, A. (King Saud bin Abdulaziz University for Health Sciences) ; Khan, R. (King Saud bin Abdulaziz University for Health Sciences) ; Al Raiy, B. (King Saud bin Abdulaziz University for Health Sciences) ; Arabi, Y. (King Saud bin Abdulaziz University for Health Sciences) ; Talaie, H. (Shahid Beheshti University of Medical Sciences(Iran)) ; Van Oers, J. A. (St. Elisabeth Hospital (Holanda)) ; Harts, A. (St. Elisabeth Hospital (Holanda)) ; Nieuwkoop, E. (St. Elisabeth Hospital (Holanda)) ; Vos, P. (St. Elisabeth Hospital (Holanda)) ; Boussarsar, Y. (Mongi Slim University Hospital) ; Boutouta, F. (Mongi Slim University Hospital) ; Kamoun, S. (Mongi Slim University Hospital) ; Mezghani, I. (Mongi Slim University Hospital) ; Koubaji, S. (Mongi Slim University Hospital) ; Ben Souissi, A. (Mongi Slim University Hospital) ; Riahi, A. (Mongi Slim University Hospital) ; Mebazaa, M. S. (Mongi Slim University Hospital) ; Giamarellos-Bourboulis, E. (University of Athens) ; Tziolos, N. (University of Athens) ; Routsi, C. (University of Athens) ; Katsenos, C. (Korgialeneion Benakeion Hospital) ; Tsangaris, I. (University of Athens) ; Pneumatikos, I. (University of Thrace) ; Vlachogiannis, G. (Aghios Dimitrios Hospital) ; Theodorou, V. (University of Thrace) ; Prekates, A. (Tzaneion Hospital) ; Antypa, E. (G.Gennimatas General Hospital) ; Koulouras, V. (University of Ioannina) ; Kapravelos, N. (G.Papanikolaou General Hospital) ; Gogos, C. (University of Patras) ; Antoniadou, E. (G.Gennimatas General Hospital) ; Mandragos, K. (Korgialeneion Benakeion Hospital) ; Armaganidis, A. (University of Athens) ; Robles Caballero, A. R. (Hospital Universitario La Paz) ; Civantos, B. (Hospital Universitario La Paz) ; Figueira, J. C. (Hospital Universitario La Paz) ; López, J. (Hospital Universitario La Paz) ; Silva-Pinto, A. (Centro Hospitalar São João (Portugal)) ; Ceia, F. (Centro Hospitalar São João (Portugal)) ; Sarmento, A. (Centro Hospitalar São João (Portugal)) ; Santos, L. (Centro Hospitalar São João (Portugal)) ; Almekhlafi, G. (PSMM (Aràbia Saudí)) ; Sakr, Y. (UNIKLINIKUM JENA) ; Al-Dorzi, H. (King Saud bin Abdulaziz University for Health Sciences) ; Khan, R. (King Saud bin Abdulaziz University for Health Sciences, Riyadh) ; Baharoon, S. (King Saud bin Abdulaziz University for Health Sciences) ; Aldawood, A. (King Saud bin Abdulaziz University for Health Sciences) ; Matroud, A. (King Saud bin Abdulaziz University for Health Sciences) ; Alchin, J. (King Saud bin Abdulaziz University for Health Sciences) ; Al Johani, S. (King Saud bin Abdulaziz University for Health Sciences) ; Balkhy, H. (King Saud bin Abdulaziz University for Health Sciences) ; Arabi, Y. (King Saud bin Abdulaziz University for Health Sciences) ; Alsolamy, S. (King Saud bin Abdulaziz University for Health Sciences) ; Yousif, S. Y. (King Saud bin Abdulaziz University for Health Sciences) ; Alotabi, B. O. (King Fahad Medical City) ; Alsaawi, A. S. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center) ; Ang, J. (Addenbrooke's Hospital) ; Curran, M. D. (Addenbrooke's Hospital) ; Enoch, D. (Addenbrooke's Hospital) ; Navapurkar, V. (Addenbrooke's Hospita) ; Morris, A. (University of Cambridge) ; Sharvill, R. (Royal United Hospital) ; Astin, J. (Royal United Hospital) ; Heredia-Rodríguez, M. (Hospital Clínico Universitario de Valladolid) ; Gómez-Sánchez, E. (Hospital Clínico Universitario de Valladolid) ; Peláez-Jareño, M. T. (Hospital Clínico Universitario de Valladolid) ; Gómez-Pesquera, E. (Hospital Clínico Universitario de Valladolid) ; Liu-Zhu, P. (Hospital Clínico Universitario de Valladolid) ; Aragón-Camino, M. (Hospital Clínico Universitario de Valladolid) ; Hernández-Lozano, A. (Hospital Clínico Universitario de Valladolid) ; Sánchez-López, A. (Hospital Clínico Universitario de Valladolid) ; Álvarez-Fuente, E. (Hospital Clínico Universitario de Valladolid, Valladolid, Spain) ; Tamayo, E. (Hospital Clínico Universitario de Valladolid, Valladolid, Spain) ; Patel, J. (Salford Royal Hospital, London, UK) ; Kruger, C. (Salford Royal Hospital, London, UK) ; O'Neal, J. (Hennepin County Medical Center, Minneapolis, USA) ; Rhodes, H. (Hennepin County Medical Center, Minneapolis, USA) ; Jancik, J. (Hennepin County Medical Center, Minneapolis, USA) ; François, B. (CHU Dupuytren, Limoges, France) ; Laterre, P. F. (St Luc University Hospital, Brussels, Belgium) ; Eggimann, P. (CHUV, Lausanne, Switzerland) ; Torres, A. (Hospital Clinic of Barcelona, Barcelona, Spain) ; Sánchez, M. (Hospital Clínico San Carlos, Madrid, Spain) ; Dequin, P. F. (Université François Rabelais and CHU Bretonneau, Tours, France) ; Bassi, G. L. (Hospital Clinic of Barcelona, Barcelona, Spain) ; Chastre, J. (Groupe Hospitalier Pitié-Salpêtrière, Paris, France) ; Jafri, H. S. (MedImmune, Gaithersburg, USA) ; Ben Romdhane, M. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Douira, Z. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Kamoun, S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Bousselmi, M. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Ben Souissi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Boussarsar, Y. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Riahi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Mebazaa, M. S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Vakalos, A. (Xanthi General Hospital, Xanthi, Greece) ; Avramidis, V. (Xanthi General Hospital, Xanthi, Greece) ; Craven, T. H. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Wojcik, G. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Kefala, K. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; McCoubrey, J. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Reilly, J. (Health Protection Scotland, Glasgow, UK) ; Paterson, R. (Western General Hospital, Edinburgh, UK) ; Inverarity, D. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Laurenson, I. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Walsh, T. S. (Royal Infirmary of Edinburgh, Edinburgh, UK) ; Mongodi, S. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Bouhemad, B. (Centre Hospitalier Universitaire Dijon, Dijon, France) ; Orlando, A. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Stella, A. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Via, G. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Iotti, G. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Braschi, A. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Mojoli, F. (Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy) ; Haliloglu, M. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Bilgili, B. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Kasapoglu, U. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Sayan, I. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Süzer Aslan, M. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Yalcin, A. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Cinel, I. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Vakalos, A. (Xanthi General Hospital, Xanthi, Greece) ; Avramidis, V. (Xanthi General Hospital, Xanthi, Greece) ; Ellis, H. E. (Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK) ; Bauchmuller, K. (Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK) ; Miller, D. (Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK) ; Temple, A. (Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK) ; Chastre, J. (Groupe Hospitalier Pitié-Salpêtrière, Paris, France) ; François, B. (CHU Dupuytren, Limoges, France) ; Torres, A. (Hospital Clinic of Barcelona, Barcelona, Spain) ; Luyt, C. E. (Groupe Hospitalier Pitié-Salpêtrière, Paris, France) ; Sánchez, M. (Hospital Clínico San Carlos, Madrid, Spain) ; Singer, M. (University College, London, UK) ; Jafri, H. S. (MedImmune, Gaithersburg, USA) ; Nassar, Y. (Cairo University, Giza, Egypt) ; Ayad, M. S. (Cairo University, Giza, Egypt) ; Trifi, A. (University hospital Center of La Rabta, Tunis, Tunisia) ; Abdellatif, S. (University hospital Center of La Rabta, Tunis, Tunisia) ; Daly, F. (University hospital Center of La Rabta, Tunis, Tunisia) ; Nasri, R. (University hospital Center of La Rabta, Tunis, Tunisia) ; Ben Lakhal, S. (University hospital Center of La Rabta, Tunis, Tunisia) ; Bilgili, B. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Haliloglu, M. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Gul, F. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Cinel, I. (Marmara University Pendik Teaching and Research Hospital, Istanbul, Turkey) ; Kuzovlev, A. (V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia) ; Shabanov, A. (N.V. Sklifosofsky Institute of Emergency Medicine, Moscow, Russia) ; Polovnikov, S. (NN Burdenko Main Military Hospital, Moscow, Russia) ; Moroz, V. (V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia) ; Kadrichu, N. (Novartis Pharmaceuticals, San Carlos, USA) ; Dang, T. (Novartis Pharmaceuticals, San Carlos, USA) ; Corkery, K. (Novartis Pharmaceuticals, San Carlos, USA) ; Challoner, P. (Nektar Therapeutics, San Francisco, CA USA) ; Bassi, Gianluigi Li (Hospital Clinic, Barcelona, Spain) ; Aguilera, E. (Hospital Clinic, Barcelona, Spain) ; Chiurazzi, C. (Hospital Clinic, Barcelona, Spain) ; Travierso, C. (Hospital Clinic, Barcelona, Spain) ; Motos, A. (Hospital Clinic, Barcelona, Spain) ; Fernandez, L. (Hospital Clinic, Barcelona, Spain) ; Amaro, Rosanel (Hospital Clinic, Barcelona, Spain) ; Senussi, Tarek (Hospital Clinic, Barcelona, Spain) ; Idone, Francesco Antonio (Hospital Clinic, Barcelona, Spain) ; Bobi, Joaquim (Hospital Clinic, Barcelona, Spain) ; Rigol, M. (Hospital Clinic, Barcelona, Spain) ; Torres, A. (Hospital Clinic, Barcelona, Spain) ; Hodiamont, Caspar J. (Academic Medical Center, Amsterdam, Netherlands) ; Juffermans, Nicole P. (Academic Medical Center, Amsterdam, Netherlands) ; Janssen, J. M. (Academic Medical Center, Amsterdam, Netherlands) ; Bouman, C. S. (Academic Medical Center, Amsterdam, Netherlands) ; Mathôt, R. A. (Academic Medical Center, Amsterdam, Netherlands) ; De Jong, M. D. (Academic Medical Center, Amsterdam, Netherlands) ; Van Hest, R. M. (Academic Medical Center, Amsterdam, Netherlands) ; Payne, L. (Maine Medical Center, Portland, USA) ; Fraser, G. L. (Maine Medical Center, Portland, USA) ; Tudor, B. (Medical University of Vienna, Vienna, Austria) ; Lahner, M. (Medical University of Vienna, Vienna, Austria) ; Roth, G. (Medical University of Vienna, Vienna, Austria) ; Krenn, C. (Medical University of Vienna, Vienna, Austria) ; Talaie, H. (Toxicological Research Center, Department of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran) ; Jault, P. (HIA Percy, Clamart, France) ; Gabard, J. (Pherecydes Pharma, Romainville, France) ; Leclerc, T. (HIA Percy, Clamart, France) ; Jennes, S. (Hôpital Reine Astrid, Brussels, Belgium) ; Que, Y. (CHUV, Lausanne, Switzerland) ; Rousseau, A. (CHU Liege, Liege, Belgium) ; Ravat, F. (CH Saint Jospeh Saint Luc, Lyon, France) ; Al-Dorzi, H. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Eissa, A. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Al-Harbi, S. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Aldabbagh, T. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Khan, R. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Arabi, Y. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Trifi, A. (University hospital center of La Rabta, Tunis, Tunisia) ; Abdellatif., S. (University hospital center of La Rabta, Tunis, Tunisia) ; Daly, F. (University hospital center of La Rabta, Tunis, Tunisia) ; Nasri, R. (University hospital center of La Rabta, Tunis, Tunisia) ; Ben Lakhal, S. (University hospital center of La Rabta, Tunis, Tunisia) ; Paramba, F. (Hamad Medical Corporation, Doha, Qatar) ; Purayil, N. (Hamad Medical Corporation, Doha, Qatar) ; Naushad, V. (Hamad Medical Corporation, Doha, Qatar) ; Mohammad, O. (Hamad Medical Corporation, Doha, Qatar) ; Negi, V. (Hamad Medical Corporation, Doha, Qatar) ; Chandra, P. (Hamad Medical Corporation, Doha, Qatar) ; Kleinsasser, A. (MUI, Innsbruck, Austria) ; Witrz, M. R. (Academic Medical Centre, Amsterdam, Netherlands) ; Buchner-Doeven, J. F. (Academic Medical Centre, Amsterdam, Netherlands) ; Tuip-de Boer, A. M. (Academic Medical Centre, Amsterdam, Netherlands) ; Goslings, J. C. (Academic Medical Centre, Amsterdam, Netherlands) ; Juffermans, N. P. (Academic Medical Centre, Amsterdam, Netherlands) ; Van Hezel, M. (Academic Medical Center Amsterdam, Amsterdam, Netherlands) ; Straat, M. (Academic Medical Center Amsterdam, Amsterdam, Netherlands) ; Boing, A. (Academic Medical Center Amsterdam, Amsterdam, Netherlands) ; Van Bruggen, R. (Sanquin, Amsterdam, Netherlands) ; Juffermans, N. (Academic Medical Center Amsterdam, Amsterdam, Netherlands) ; Markopoulou, D. (KAT Hospital Athens, Kifisia, Greece) ; Venetsanou, K. (KAT Hospital Athens, Kifisia, Greece) ; Kaldis, V. (KAT Hospital Athens, Kifisia, Greece) ; Koutete, D. (KAT Hospital Athens, Kifisia, Greece) ; Chroni, D. (KAT Hospital Athens, Kifisia, Greece) ; Alamanos, I. (ICU-B, KAT Hospital Kifisia, Athens, Greece) ; Koch, L. (Hennepin County Medical Center, Minneapolis, USA) ; Jancik, J. (Hennepin County Medical Center, Minneapolis, USA) ; Rhodes, H. (Hennepin County Medical Center, Minneapolis, USA) ; Walter, E. (Hennepin County Medical Center, Minneapolis, USA) ; Maekawa, K. (Hokkaido University Hospital, Sapporo, Japan) ; Hayakawa, M. (Hokkaido University Hospital, Sapporo, Japan) ; Kushimoto, S. (Tohoku University Graduate School of Medicine, Sendai, Japan) ; Shiraishi, A. (Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan) ; Kato, H. (National Hospital Organization Disaster Medical Center, Tokyo, Japan) ; Sasaki, J. (Keio University School of Medicine, Tokyo, Japan) ; Ogura, H. (Osaka University Graduate School of Medicine, Osaka, Japan) ; Matauoka, T. (Rinku General Medical Center, Osaka, Japan) ; Uejima, T. (Kinki University Faculty of Medicine, Osaka, Japan) ; Morimura, N. (Yokohama City University Graduate School of Medicine, Yokohama, Japan) ; Ishikura, H. (Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ; Hagiwara, A. (National Center For Global Health and Medicine, Tokyo, Japan) ; Takeda, M. (Tokyo Women's Medical University, Tokyo, Japan) ; Tarabrin, O. (Odessa National Medical University, Odessa, Ukraine) ; Shcherbakow, S. (Odessa National Medical University, Odessa, Ukraine) ; Gavrychenko, D. (Odessa National Medical University, Odessa, Ukraine) ; Mazurenko, G. (Odessa National Medical University, Odessa, Ukraine) ; Ivanova, V. (Odessa National Medical University, Odessa, Ukraine) ; Chystikov, O. (Odessa National Medical University, Odessa, Ukraine) ; Plourde, C. (Hopital Sacré-Coeur de Montréal, Montreal, Canada) ; Lessard, J. (Hopital Sacré-Coeur de Montréal, Montreal, Canada) ; Chauny, J. ; Daoust, R. (Hopital Sacré-Coeur de Montréal, Montreal, Canada) ; Shcherbakow, S. (Odessa National Medical University, Odessa, Ukraine) ; Tarabrin, O. (Odessa National Medical University, Odessa, Ukraine) ; Gavrychenko, D. (Odessa National Medical University, Odessa, Ukraine) ; Mazurenko, G. (Odessa National Medical University, Odessa, Ukraine) ; Chystikov, O. (Odessa National Medical University, Odessa, Ukraine) ; Vakalos, A. (Xanthi General Hospital, Xanth, Greece) ; Avramidis, V. (Xanthi General Hospital, Xanth, Greece) ; Kropman, L. (Maastricht UMC, Maastricht, Netherlands) ; In het Panhuis, L. (Maastricht UMC, Maastricht, Netherlands) ; Konings, J. (Maastricht UMC, Maastricht, Netherlands) ; Huskens, D. (Maastricht UMC, Maastricht, Netherlands) ; Schurgers, E. (Maastricht UMC, Maastricht, Netherlands) ; Roest, M. (Maastricht UMC, Maastricht, Netherlands) ; De Laat, B. (Maastricht UMC, Maastricht, Netherlands) ; Lance, M. (Maastricht UMC, Maastricht, Netherlands) ; Durila, M. (Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic) ; Lukas, P. (Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic) ; Astraverkhava, M. (Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic) ; Jonas, J. (Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic) ; Budnik, I. (Sechenov First Moscow Stat Medical University, Moscow, Russia) ; Shenkman, B. (Sheba Medical Center, Tel-Hashomer, Israel) ; Hayami, H. (Yokohama Municipal Citizen's Hospital, Yokohama, Japan) ; Koide, Y. (Hayama Heart Center, Hayama, Japan) ; Goto, T. (Yokohama City University Hospital, Yokohama, Japan) ; Iqbal, R. (Institute of Ageing and Chronic Disease, Liverpool, UK) ; Alhamdi, Y. (Institute of Infection and Global Health, Liverpool, UK) ; Venugopal, N. (Institute of Ageing and Chronic Disease, Liverpool, UK) ; Abrams, S. (Institute of Infection and Global Health, Liverpool, UK) ; Downey, C. (Department of Haematology, Royal Liverpool University Hospital (RLUH), Liverpool, UK) ; Toh, C. H. (Institute of Infection and Global Health, Liverpool, UK) ; Welters, I. D. (Institute of Ageing and Chronic Disease, Liverpool, UK) ; Bombay, V. B. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Chauny, J. M. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Daoust, R. D. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Lessard, J. L. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Marquis, M. M. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Paquet, J. P. (Hôpital du Sacré-Coeur de Montréal, Montreal, Canada) ; Siemens, K. (Evelina London Children's Hospital, London, UK) ; Sangaran, D. (Evelina London Children's Hospital, London, UK) ; Hunt, B. J. (St Thomas Hospital, London, UK) ; Durward, A. (Evelina London Children's Hospital, London, UK) ; Nyman, A. (Evelina London Children's Hospital, London, UK) ; Murdoch, I. A. (Evelina London Children's Hospital, London, UK) ; Tibby, S. M. (Evelina London Children's Hospital, London, UK) ; Ampatzidou, F. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Moisidou, D. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Dalampini, E. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Nastou, M. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Vasilarou, E. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Kalaizi, V. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Chatzikostenoglou, H. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Drossos, G. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Spadaro, S. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Fogagnolo, A. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Fiore, T. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Schiavi, A. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Fontana, V. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Taccone, F. (Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Bruxelles, Belgium) ; Volta, C. (Intensive Care Unit, University of Ferrara, Italy, Ferrara, Italy) ; Chochliourou, E. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Volakli, E. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Violaki, A. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Samkinidou, E. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Evlavis, G. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Panagiotidou, V. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Sdougka, M. (Hippokration General Hospital Thessaloniki, Thessaloniki, Greece) ; Mothukuri, R. (Morriston Hospital, Swansea, UK) ; Battle, C. (Morriston Hospital, Swansea, UK) ; Guy, K. (Morriston Hospital, Swansea, UK) ; Mills, G. (Morriston Hospital, Swansea, UK) ; Evans, P. (Morriston Hospital, Swansea, UK) ; Wijesuriya, J. (Central London School of Anaesthesia and Intensive Care Medicine, London, UK) ; Keogh, S. (University of the Sunshine Coast, Maroochydore, Australia) ; Docherty, A. (University of Edinburgh, Edinburgh, UK) ; O'Donnell, R. (University of Edinburgh, Edinburgh, UK) ; Brunskill, S. (John Radcliffe Hospital, Oxford, UK) ; Trivella, M. (John Radcliffe Hospital, Oxford, UK) ; Doree, C. (John Radcliffe Hospital, Oxford, UK) ; Holst, L. (Copenhagen University Hospital, Copenhagen, Denmark) ; Parker, M. (Peterborough NHS Trust, Peterborough, UK) ; Gregersen, M. (Aarhus University, Aarhus, Denmark) ; Almeida, J. (Hospital de Sao Paulo, Sao Paulo, Brazil) ; Walsh, T. (University of Edinburgh, Edinburgh, UK) ; Stanworth, S. (John Radcliffe Hospital, Oxford, UK) ; Moravcova, S. (Royal Brompton & Harefield NHS Trust, London, UK) ; Mansell, J. (Barts Heart Centre, London, UK) ; Rogers, A. (Barts Heart Centre, London, UK) ; Smith, R. A. (Barts Heart Centre, London, UK) ; Hamilton-Davies, C. (Barts Heart Centre, London, UK) ; Omar, A. (Hamad medical corporation, Doha, Qatar) ; Allam, M. (Hamad medical corporation, Doha, Qatar) ; Bilala, O. (Hamad medical corporation, Doha, Qatar) ; Kindawi, A. (Hamad medical corporation, Doha, Qatar) ; Ewila, H. (Hamad medical corporation, Doha, Qatar) ; Ampatzidou, F. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Moisidou, D. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Nastou, M. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Dalampini, E. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Malamas, A. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Vasilarou, E. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Drossos, G. (G.Papanikolaou General Hospital, Thessaloniki, Greece) ; Ferreira, G. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Caldas, J. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Fukushima, J. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Osawa, E. A. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Arita, E. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Camara, L. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Zeferino, S. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Jardim, J. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Gaioto, F. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Dallan, L. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Jatene, F. B. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Kalil Filho, R. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Galas, F. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Hajjar, L. A. (University of Sao Paulo, Brazi, Sao Paulo, Brazil) ; Mitaka, C. (Juntendo University Hospital, Tokyo, Japan) ; Ohnuma, T. ; Murayama, T. (Saitama Medical Center, Jichi Medical University, Saitama, Japan) ; Kunimoto, F. (Gunma University Hospital, Maebashi, Japan) ; Nagashima, M. (Yokohama City Minato Red Cross Hospital, Yokohama, Japan) ; Takei, T. (Yokohama City Minato Red Cross Hospital, Yokohama, Japan) ; Tomita, M. (Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan) ; Omar, A. (Hamad medical corporation, Doha, Qatar) ; Mahmoud, K. (Hamad medical corporation, Doha, Qatar) ; Hanoura, S. (Hamad medical corporation, Doha, Qatar) ; Sudarsanan, S. (Hamad medical corporation, Doha, Qatar) ; Sivadasan, P. (Hamad medical corporation, Doha, Qatar) ; Othamn, H. (Hamad medical corporation, Doha, Qatar) ; Shouman, Y. (Hamad medical corporation, Doha, Qatar) ; Singh, R. (Hamad medical corporation, Doha, Qatar) ; Al Khulaifi, A. (Hamad medical corporation, Doha, Qatar) ; Mandel, I. (Research Institution for Cardiology, Tomsk, Russia) ; Mikheev, S. (Research Institution for Cardiology, Tomsk, Russia) ; Suhodolo, I. (Siberian State Medical University, Tomsk, Russia) ; Kiselev, V. (Research Institution for Cardiology, Tomsk, Russia) ; Svirko, Y. (Research Institution for Cardiology, Tomsk, Russia) ; Podoksenov, Y. (Research Institution for Cardiology, Tomsk, Russia) ; Jenkins, S. A. (The Hillingdon Hospitals NHS Foundation Trust, Middlesex, UK) ; Griffin, R. (The Hillingdon Hospitals NHS Foundation Trust, Middlesex, UK) ; Tovar Doncel, M. S. (University Hospital Rio Hortega, Valladolid, Spain) ; Lima, A. (Erasmus MC, Rotterdam, Netherlands) ; Aldecoa, C. (University Hospital Rio Hortega, Valladolid, Spain) ; Ince, C. (Erasmus MC, Rotterdam, Netherlands) ; Taha, A. (Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates) ; Shafie, A. (Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates) ; Mostafa, M. (Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates) ; Syed, N. (Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates) ; Hon, H. (Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates) ; Righetti, F. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Colombaroli, E. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Castellano, G. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Righetti, F. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Colombaroli, E. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Hravnak, M. (University of Pittsburgh, Pittsburgh, USA) ; Chen, L. C. (Carnegie Mellon University, Pittsburgh, USA) ; Dubrawski, A. D. (Carnegie Mellon University, Pittsburgh, USA) ; Clermont, G. C. (University of Pittsburgh, Pittsburgh, USA) ; Pinsky, M. R. (University of Pittsburgh, Pittsburgh, USA) ; Gonzalez, S. (Valme University Hospital, Seville, Spain) ; Macias, D. (Valme University Hospital, Seville, Spain) ; Acosta, J. (Valme University Hospital, Seville, Spain) ; Jimenez, P. (Valme University Hospital, Seville, Spain) ; Loza, A. (Valme University Hospital, Seville, Spain) ; Lesmes, A. (Valme University Hospital, Seville, Spain) ; Lucena, F. (Valme University Hospital, Seville, Spain) ; Leon, C. (Valme University Hospital, Seville, Spain) ; Tovar Doncel, M. S. (University Hospital Rio Hortega, Valladolid, Spain) ; Ince, C. (Erasmus MC, Rotterdam, Netherlands) ; Aldecoa, C. (University Hospital Rio Hortega, Valladolid, Spain) ; Lima, A. (Erasmus MC, Rotterdam, Netherlands) ; Bastide, M. (CHU Amiens, Amiens, France) ; Richecoeur, J. (CH Beauvais, Beauvais, France) ; Frenoy, E. (Réanimation polyvalente, Le Havre, France) ; Lemaire, C. (CH Roubaix, Roubaix, France) ; Sauneuf, B. (CH Cotentin, Cherbourg, France) ; Tamion, F. (CHU Rouen, Rouen, France) ; Nseir, S. (CHU Lille, Lille, France) ; Du Cheyron, D. (CHU Caen, Caen, France) ; Dupont, H. (CHU Amiens, Amiens, France) ; Maizel, J. (CHU Amiens, Amiens, France) ; Shaban, M. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; Kolko, R. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; Salahuddin, N. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; Sharshir, M. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; AbuRageila, M. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; AlHussain, A. (King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia) ; Mercado, P. (CHU Amiens, Amiens, France) ; Maizel, J. (CHU Amiens, Amiens, France) ; Kontar, L. (CHU Amiens, Amiens, France) ; Titeca, D. (CHU Amiens, Amiens, France) ; Brazier, F. (CHU Amiens, Amiens, France) ; Riviere, A. (CHU Amiens, Amiens, France) ; Joris, M. (CHU Amiens, Amiens, France) ; Soupison, T. (CHU Amiens, Amiens, France) ; De Cagny, B. (CHU Amiens, Amiens, France) ; Slama, M. (CHU Amiens, Amiens, France) ; Wagner, J. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Körner, A. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Kubik, M. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Kluge, S. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Reuter, D. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Saugel, B. (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ; Colombaroli, E. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Righetti, F. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Castellano, G. (Intensive Care Unit, St. Boniface Hospital, Verona, Italy) ; Tran, T. (Brugmann Hospital, Brussels, Belgium) ; De Bels, D. (Brugmann Hospital, Brussels, Belgium) ; Cudia, A. (Brugmann Hospital, Brussels, Belgium) ; Strachinaru, M. (Brugmann Hospital, Brussels, Belgium) ; Ghottignies, P. (Brugmann Hospital, Brussels, Belgium) ; Devriendt, J. (Brugmann Hospital, Brussels, Belgium) ; Pierrakos, C. (Brugmann Hospital, Brussels, Belgium) ; Martínez González, Ó. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Blancas, R. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Luján, J. (Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain) ; Ballesteros, D. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Martínez Díaz, C. (Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain) ; Núñez, A. (Hospital Universitario de San Carlos, Madrid, Spain) ; Martín Parra, C. (Hospital Universitario del Tajo, Aranjuez, Spain) ; López Matamala, B. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Alonso Fernández, M. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Chana, M. (Hospital Universitario del Tajo, Aranjuez, Spain) ; Huber, W. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Eckmann, M. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Elkmann, F. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Gruber, A. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Klein, I. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Schmid, R. M. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Lahmer, T. (Klinikum rechts der Isar, Technical University of Munich, Munich, Germany) ; Moller, P. W. (Department of Intensive Care Medicine, University Hospital Bern, Bern, Switzerland) ; Sondergaard, S. (Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden) ; Jakob, S. M. (Department of Intensive Care Medicine, University Hospital Bern, Bern, Switzerland) ; Takala, J. (Department of Intensive Care Medicine, University Hospital Bern, Bern, Switzerland) ; Berger, D. (Department of Intensive Care Medicine, University Hospital Bern, Bern, Switzerland) ; Bastoni, D. (St George's Healthcare NHS Trust, London, UK) ; Aya, H. (St George's Healthcare NHS Trust, London, UK) ; Toscani, L. (St George's Healthcare NHS Trust, London, UK) ; Pigozzi, L. (St George's Healthcare NHS Trust, London, UK) ; Rhodes, A. (St George's Healthcare NHS Trust, London, UK) ; Cecconi, M. (St George's Healthcare NHS Trust, London, UK) ; Ostrowska, C. (St George's Healthcare NHS Trust, London, UK) ; Aya, H. (St George's Healthcare NHS Trust, London, UK) ; Abbas, A. (St George's Healthcare NHS Trust, London, UK) ; Mellinghoff, J. (St George's Healthcare NHS Trust, London, UK) ; Ryan, C. (St George's Healthcare NHS Trust, London, UK) ; Dawson, D. (St George's Healthcare NHS Trust, London, UK) ; Rhodes, A. (St George's Healthcare NHS Trust, London, UK) ; Cecconi, M. (St George's Healthcare NHS Trust, London, UK) ; Cronhjort, M. (Karolinska Institutet, Stockholm, Sweden) ; Wall, O. (Karolinska Institutet, Stockholm, Sweden) ; Nyberg, E. (Karolinska Institutet, Stockholm, Sweden) ; Zeng, R. (Wenzhou Medical University, Wenzhou, Zheijang China) ; Svensen, C. (Karolinska Institutet, Stockholm, Sweden) ; Mårtensson, J. (Department of Intensive Care, Austin Hospital, Melbourne, VIC Australia) ; Joelsson-Alm, E. (Karolinska Institutet, Stockholm, Sweden) ; Aguilar Arzapalo, Mario Francisco (Hospital O'horan, Mérida, Mexico) ; Barradas, L. (Hospital O'horan, Mérida, Mexico) ; Lopez, V. (Hospital O'horan, Mérida, Mexico) ; Cetina, M. (Hospital O'horan, Mérida, Mexico) ; Parenti, N. (Policlinico Modena, Bologna, Italy) ; Palazzi, C. (Policlinico Modena, Bologna, Italy) ; Amidei, L. A. (Policlinico Modena, Bologna, Italy) ; Borrelli, F. B. (Policlinico Modena, Bologna, Italy) ; Campanale, S. C. (Policlinico Modena, Bologna, Italy) ; Tagliazucchi, F. T. (Policlinico Modena, Bologna, Italy) ; Sedoni, G. S. (Policlinico Modena, Bologna, Italy) ; Lucchesi, D. L. (Policlinico Modena, Bologna, Italy) ; Carella, E. C. (Policlinico Modena, Bologna, Italy) ; Luciani, A. L. (Policlinico Modena, Bologna, Italy) ; Mackovic, M. (Clinical Hospital Sveti Duh, Zagreb, Croatia) ; Maric, N. (Clinical Hospital Sveti Duh, Zagreb, Croatia) ; Bakula, M. (Clinical Hospital Sveti Duh, Zagreb, Croatia) ; Aya, H. (St George's Healthcare NHS Trust, London, UK) ; Rhodes, A. (St George's Healthcare NHS Trust, London, UK) ; Grounds, R. M. (St George's Healthcare NHS Trust, London, UK) ; Fletcher, N. (St George's Healthcare NHS Trust, London, UK) ; Cecconi, M. (St George's Healthcare NHS Trust, London, UK) ; Avard, B. (The Canberra Hospital, Hughes, ACT Australia) ; Zhang, P. (Australian National University Medical School, Canberra, Australia) ; Mezidi, M. (Lapeyronie University Hospital, Montpellier, France) ; Charbit, J. (Lapeyronie University Hospital, Montpellier, France) ; Ould-Chikh, M. (Lapeyronie University Hospital, Montpellier, France) ; Deras, P. (Lapeyronie University Hospital, Montpellier, France) ; Maury, C. (Lapeyronie University Hospital, Montpellier, France) ; Martinez, O. (Lapeyronie University Hospital, Montpellier, France) ; Capdevila, X. (Lapeyronie University Hospital, Montpellier, France) ; Hou, P. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Linde-Zwirble, W. Z. (Trexin Medical, Chicago, USA) ; Douglas, I. D. (University of Colorado and Denver Health, Denver, USA) ; Shapiro, N. S. (Beth Isreal Deaconess, Boston, USA) ; Ben Souissi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Mezghani, I. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Ben Aicha, Y. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Kamoun, S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Laribi, B. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Jeribi, B. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Riahi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Mebazaa, M. S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Pereira, C. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Antunes, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Crivits, M. (University Hospital, Ghent, Belgium) ; Raes, M. (University Hospital, Ghent, Belgium) ; Decruyenaere, J. (University Hospital, Ghent, Belgium) ; Hoste, E. (University Hospital, Ghent, Belgium) ; Bagin, V. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Rudnov, V. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Savitsky, A. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Astafyeva, M. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Korobko, I. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Vein, V. (City Clinical Hospital 40, Yekaterinburg, Russia) ; Kampmeier, T. (University Hospital Muenster, Muenster, Germany) ; Arnemann, P. (University Hospital Muenster, Muenster, Germany) ; Hessler, M. (University Hospital Muenster, Muenster, Germany) ; Wald, A. (Marienhospital Osnabrück, Osnabrück, Germany) ; Bockbreder, K. (Charité, University of Berlin, Berlin, Germany) ; Morelli, A. (Sapienza University of Rome, Rome, Italy) ; Van Aken, H. (University Hospital Muenster, Muenster, Germany) ; Rehberg, S. (University Hospital of Greifswald, Greifswald, Germany) ; Ertmer, C. (University Hospital Muenster, Muenster, Germany) ; Arnemann, P. (University Hospital of Muenster, Muenster, Germany) ; Hessler, M. (University Hospital of Muenster, Muenster, Germany) ; Kampmeier, T. (University Hospital of Muenster, Muenster, Germany) ; Rehberg, S. (University Hospital of Greifswald, Greifswald, Germany) ; Van Aken, H. (University Hospital of Muenster, Muenster, Germany) ; Ince, C. (Erasmus MC University Hospital Rotterdam, Rotterdam, Netherlands) ; Ertmer, C. (University Hospital of Muenster, Muenster, Germany) ; Reddy, S. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Bailey, M. (Monash University, Melbourne, Australia) ; Beasley, R. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Bellomo, Rinaldo (Austin Hospital, Melbourne, Australia) ; Mackle, D. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Psirides, A. (Wellington Regional Hospital, Wellington, New Zealand) ; Young, P. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Reddy, S. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Bailey, M. (Australian and New Zealand Intensive Care Research Centre, Melbourne, Australia) ; Beasley, R. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Bellomo, Rinaldo (Austin Hospital, Melbourne, Australia) ; Mackle, D. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Young, P. (Medical Research Institute of New Zealand, Wellington, New Zealand) ; Venkatesh, H. (Prince of Wales Hospital (Australia)) ; Ramachandran, S. (Imperial College London) ; Basu, A. (Glan Clwyd Hospital, Bodelwyddan, UK) ; Nair, H. (Glan Clwyd Hospital, Bodelwyddan, UK) ; Egan, S. (University Hospital Galway, Galway, Ireland) ; Bates, J. (University Hospital Galway, Galway, Ireland) ; Oliveira, S. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Rangel Neto, N. R. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Reis, F. Q. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Lee, C. P. (Tan Tock Seng Hospital, Singapore, Singapore) ; Lin, X. L. (National Neuroscience Institute, Singapore, Singapore) ; Choong, C. (Tan Tock Seng Hospital, Singapore, Singapore) ; Eu, K. M. (Tan Tock Seng Hospital, Singapore, Singapore) ; Sim, W. Y. (Tan Tock Seng Hospital, Singapore, Singapore) ; Tee, K. S. (Tan Tock Seng Hospital, Singapore, Singapore) ; Pau, J. (Tan Tock Seng Hospital, Singapore, Singapore) ; Abisheganaden, J. (Tan Tock Seng Hospital, Singapore, Singapore) ; Maas, K. (Erasmus Medical Centre, Rotterdam, Netherlands) ; De Geus, H. (Erasmus Medical Centre, Rotterdam, Netherlands) ; Lafuente, E. (Centro Hospitalar Tamega e Sousa, Penafiel, Portugal) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Moura, J. (Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal) ; Antunes, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Doris, T. E. (South Tees NHS Trust, Middlesbrough, UK) ; Monkhouse, D. (South Tees NHS Trust, Middlesbrough, UK) ; Shipley, T. (South Tees NHS Trust, Middlesbrough, UK) ; Kardasz, S. (South Tees NHS Trust, Middlesbrough, UK) ; Gonzalez, I (South Tees NHS Trust, Middlesbrough, UK) ; Stads, S. (Ikazia Hospital, Rotterdam, Netherlands) ; Groeneveld, A. J. (Erasmus MC, Rotterdam, Netherlands) ; Elsayed, I. (Sheffiled Teaching Hospitals, Sheffield, UK) ; Ward, N. (Sheffiled Teaching Hospitals, Sheffield, UK) ; Tridente, A. (Whiston Hospital, St Helens & Knowsley, UK) ; Raithatha, A. (Sheffiled Teaching Hospitals, Sheffield, UK) ; Steuber, A. (University Hospital Duesseldorf, Düsseldorf, Germany) ; Pelletier, C. (University Hospital Duesseldorf, Düsseldorf, Germany) ; Schroeder, S. (University Hospital Duesseldorf, Düsseldorf, Germany) ; Michael, E. (University Hospital Duesseldorf, Düsseldorf, Germany) ; Slowinski, T. (Charite University Hospital, Berlin, Germany) ; Kindgen-Milles, D. (University Hospital Duesseldorf, Düsseldorf, Germany) ; Ghabina, S. (Royal London Hospital, London, UK) ; Turani, F. (Aurelia and European Hospital, Rome, Italy) ; Belli, A. (Aurelia and European Hospital, Rome, Italy) ; Busatti, S. (Aurelia and European Hospital, Rome, Italy) ; Barettin, G. (Aurelia and European Hospital, Rome, Italy) ; Candidi, F. (Aurelia and European Hospital, Rome, Italy) ; Gargano, F. (Aurelia and European Hospital, Rome, Italy) ; Barchetta, R. (Aurelia and European Hospital, Rome, Italy) ; Falco, M. (Aurelia and European Hospital, Rome, Italy) ; Demirkiran, O. (Istanbul University Cerrahpasa Medical School, Istanbul, Turkey) ; Kosuk, M. (Istanbul University Cerrahpasa Medical School, Istanbul, Turkey) ; Bozbay, S. (Istanbul University Cerrahpasa Medical School, Istanbul, Turkey) ; Weber, V. (Danube University Krems, Krems, Austria) ; Hartmann, J. (Danube University Krems, Krems, Austria) ; Harm, S. (Danube University Krems, Krems, Austria) ; Linsberger, I. (Danube University Krems, Krems, Austria) ; Eichhorn, T. (Danube University Krems, Krems, Austria) ; Valicek, G. (University Hospital St. Poelten, St. Poelten, Austria) ; Miestinger, G. (University Hospital St. Poelten, St. Poelten, Austria) ; Hoermann, C. (University Hospital St. Poelten, St. Poelten, Austria) ; Faenza, S. (Teaching Hospital Policlinico S.Orsola-Malpighi, Bologna, Italy) ; Ricci, D. (Department of Nephrology, Dialysis, Hypertension, Bologna, Italy) ; Mancini, E. (Department of Nephrology, Dialysis, Hypertension, Bologna, Italy) ; Gemelli, C. (Science and Technology Park for Medicine, Mirandola, Italy) ; Cuoghi, A. (Science and Technology Park for Medicine, Mirandola, Italy) ; Magnani, S. (Aferetica, Bologna, Italy) ; Atti, M. (Aferetica, Bologna, Italy) ; Laddomada, T. (San Marco Hospital, Zingonia, Italy) ; Doronzio, A. (San Marco Hospital, Zingonia, Italy) ; Balicco, B. (San Marco Hospital, Zingonia, Italy) ; Gruda, M. C. (CytoSorbents, Monmouth Junction, USA) ; O'Sullivan, P. (CytoSorbents, Monmouth Junction, USA) ; Dan, V. P. (CytoSorbents, Monmouth Junction, USA) ; Guliashvili, T. (CytoSorbents, Monmouth Junction, USA) ; Scheirer, A. (CytoSorbents, Monmouth Junction, USA) ; Golobish, T. D. (CytoSorbents, Monmouth Junction, USA) ; Capponi, V. J. (CytoSorbents, Monmouth Junction, USA) ; Chan, P. P. (CytoSorbents, Monmouth Junction, USA) ; Kogelmann, K. (Klinikum Emden, Emden, Germany) ; Drüner, M. (Klinikum Emden, Emden, Germany) ; Jarczak, D. (University Hospital Eppendorf, Hamburg, Germany) ; Turani, F. (Aurelia Hospital /European Hospital, Rome, Italy) ; Belli, A (Aurelia Hospital /European Hospital, Rome, Italy) ; Martni, S. M. (Aurelia Hospital /European Hospital, Rome, Italy) ; Cotticelli, V. C. (Aurelia Hospital /European Hospital, Rome, Italy) ; Mounajergi, F. (Aurelia Hospital /European Hospital, Rome, Italy) ; Barchetta, R. (Aurelia Hospital /European Hospital, Rome, Italy) ; Morimoto, S. (Fukuoka University hospital, Fukuoka, Japan) ; Ishikura, H. (Fukuoka University hospital, Fukuoka, Japan) ; Hussain, I. (King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia) ; Salahuddin, N. (King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia) ; Nadeem, A. (King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia) ; Ghorab, K. (King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia) ; Maghrabi, K. (King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia) ; Kloesel, S. K. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Goldfuss, C. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Stieglitz, A. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Stieglitz, A. S. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Krstevska, L. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Albuszies, G. (GPR Klinikum Ruesselsheim, Ruesselsheim, Hessen Germany) ; Aguilar Arzapalo, Mario Francisco (Hospital O'horan, Mérida, Mexico) ; Barradas, L. (Hospital O'horan, Mérida, Mexico) ; Lopez, V. (Hospital O'horan, Mérida, Mexico) ; Escalante, A. (Hospital O'horan, Mérida, Mexico) ; Jimmy, G. (Hospital O'horan, Mérida, Mexico) ; Cetina, M. (Hospital O'horan, Mérida, Mexico) ; Izawa, J. (Jikei University School of Medicine, Tokyo, Japan) ; Iwami, T. (Kyoto University, Kyoto, Japan) ; Uchino, S. (Jikei University School of Medicine, Tokyo, Japan) ; Takinami, M. (Jikei University School of Medicine, Tokyo, Japan) ; Kitamura, T. (Osaka University, Osaka, Japan) ; Kawamura, T. (Kyoto University, Kyoto, Japan) ; Powell-Tuck, J. G. (Guy's & St Thomas' NHS Foundation Trust, London, UK) ; Crichton, S. (King's College, London, UK) ; Raimundo, M. (Hospital de Santa Maria, Lisbon, Portugal) ; Camporota, L. (Guy's & St Thomas' NHS Foundation Trust, London, UK) ; Wyncoll, D. (Guy's & St Thomas' NHS Foundation Trust, London, UK) ; Ostermann, M. (Guy's & St Thomas' NHS Foundation Trust, London, UK) ; Hana, A. (ErasmusMC, Rotterdam, Netherlands) ; De Geus, H. R. (ErasmusMC, Rotterdam, Netherlands) ; Hana, A. (ErasmusMC, Rotterdam, Netherlands) ; Aydogdu, M. (Gazi University Medical Faculty, Ankara, Turkey) ; Boyaci, N. (Gazi University School of Medicine, Critical Care Fellowship Programme, Ankara, Turkey) ; Yuksel, S. (Gazi University School of Medicine Biochemistry Department, Ankara, Turkey) ; Gursel, G. (Gazi University Medical Faculty, Ankara, Turkey) ; Cayci Sivri, A. B. (Gazi University School of Medicine Biochemistry Department, Ankara, Turkey) ; Meza-Márquez, J. (Fundación Clínica Medica Sur, Mexico City, Mexico) ; Nava-López, J. (Fundación Clínica Medica Sur, Mexico City, Mexico) ; Carrillo-Esper, R. (Fundación Clínica Medica Sur, Mexico City, Mexico) ; Dardashti, A. (Skåne University Hospital (Suècia)) ; Grubb, A. (Skåne University Hospital (Suècia)) ; Maizel, J. (CHU Amiens, Amiens, France) ; Wetzstein, M. (CHU Amiens, Amiens, France) ; Titeca, D. (CHU Amiens, Amiens, France) ; Kontar, L. (CHU Amiens, Amiens, France) ; Brazier, F. (CHU Amiens, Amiens, France) ; De Cagny, B. (CHU Amiens, Amiens, France) ; Riviere, A. (CHU Amiens, Amiens, France) ; Soupison, T. (CHU Amiens, Amiens, France) ; Joris, M. (CHU Amiens, Amiens, France) ; Slama, M. (Radboudumc, Nijmegen, Netherlands) ; Peters, E. ; Njimi, H. (Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Pickkers, P. (Radboudumc, Nijmegen, Netherlands) ; Vincent, J. L. (Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Waraich, M. (The Royal Surrey County Hospital, Guildford, UK) ; Doyle, J. (The Royal Surrey County Hospital, Guildford, UK) ; Samuels, T. (The Royal Surrey County Hospital, Guildford, UK) ; Forni, L. (The Royal Surrey County Hospital, Guildford, UK) ; Desai, N. (Royal National Orthopaedic Hospital, Middlesex, UK) ; Baumber, R. (Royal National Orthopaedic Hospital, Middlesex, UK) ; Gunning, P. (Royal National Orthopaedic Hospital, Middlesex, UK) ; Sell, A. (Royal National Orthopaedic Hospital, Middlesex, UK) ; Lin, S. (Barts Health NHS Trust, London, UK) ; Torrence, H. (Queen Mary University of London, London, UK) ; O'Dwyer, M. (Queen Mary University of London, London, UK) ; Kirwan, C. (Barts Health NHS Trust, London, UK) ; Prowle, J. (Queen Mary University of London, London, UK) ; Kim, T. (Asan medical center, Seoul, South Korea) ; O'Connor, M. E. (Barts Health NHS Trust, London, UK) ; Hewson, R. W. (Barts Health NHS Trust, London, UK) ; Kirwan, C. J. (Barts Health NHS Trust, London, UK) ; Pearse, R. M. (Queen Mary University of London, London, UK) ; Prowle, J. (Queen Mary University of London, London, UK) ; Hanoura, S. (Hamad medical corporation, Doha, Qatar) ; Omar, A. (Hamad medical corporation, Doha, Qatar) ; Othamn, H. (Hamad medical corporation, Doha, Qatar) ; Sudarsanan, S. (Hamad medical corporation, Doha, Qatar) ; Allam, M. (Hamad medical corporation, Doha, Qatar) ; Maksoud, M. (Hamad medical corporation, Doha, Qatar) ; Singh, R. (Hamad medical corporation, Doha, Qatar) ; Al Khulaifi, A. (Hamad medical corporation, Doha, Qatar) ; O'Connor, M. E. (Barts Health NHS Trust, London, UK) ; Hewson, R. W. (Barts Health NHS Trust, London, UK) ; Kirwan, C. J. (Barts Health NHS Trust, London, UK) ; Pearse, R. M. (Queen Mary University of London, London, UK) ; Prowle, J. (Queen Mary University of London, London, UK) ; Uzundere, O. (Trakya Univ, Edirne, Turkey) ; Memis, D. (Trakya Univ, Edirne, Turkey) ; Ýnal, M. (Trakya Univ, Edirne, Turkey) ; Gultekin, A. (Trakya Univ, Edirne, Turkey) ; Turan, N. (Trakya Univ, Edirne, Turkey) ; Aydin, M. A. (General Directorate of Health Services, Ministry of Health, Ankara, Turkey) ; Basar, H. (AnkaraNKARA Research and Training Hospital, Ankara, Turkey) ; Sencan, I. (General Directorate of Health Services, Ministry of Health, Ankara, Turkey) ; Kapuagasi, A. (General Directorate of Health Services, Ministry of Health, Ankara, Turkey) ; Ozturk, M. (General Directorate of Health Services, Ministry of Health, Ankara, Turkey) ; Uzundurukan, Z. (General Directorate of Health Services, Ministry of Health, Ankara, Turkey) ; Gokmen, D. (Department of Biostatistics, Faculty of Medicine, Ankara University, Ankara, Turkey) ; Ozcan, A. (Ankara Research and Training Hospital, Ankara, Turkey) ; Kaymak, C. (AnkaraNKARA Research and Training Hospital, Ankara, Turkey) ; Artemenko, V. A. (MC Into-Sana, Odessa, Ukraine) ; Budnyuk, A. (MC Into-Sana, Odessa, Ukraine) ; Pugh, R. (Glan Clwyd Hospital, Rhyl, UK) ; Bhandari, S. (Glan Clwyd Hospital, Rhyl, UK) ; Mauri, T. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Turrini, C. (University of Ferrara, Sant'Anna Hospital, Ferrara, Italy) ; Langer, T. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Taccone, P. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Volta, C. A. (University of Ferrara, Sant'Anna Hospital, Ferrara, Italy) ; Marenghi, C. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Gattinoni, L. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Pesenti, A. (Fondazione IRCCS Ca' Granda, Maggiore Policlinico Hospital, Milan, Italy) ; Sweeney, L. (Aerogen, Galway, Ireland) ; O'Sullivan, A. (Aerogen, Galway, Ireland) ; Kelly, P. (Aerogen, Galway, Ireland) ; Mukeria, E. (Aerogen, Galway, Ireland) ; MacLoughlin, R. (Aerogen, Galway, Ireland) ; Pfeffer, M. (Kaplan Medical Centre, Rehovot, Israel) ; Thomas, J. T. (West Virginia University, ?, West Virginia USA) ; Bregman, G. B. (Kaplan Medical Centre, Rehovot, Israel) ; Karp, G. K. (Kaplan Medical Centre, Rehovot, Israel) ; Kishinevsky, E. K. (Kaplan Medical Centre, Rehovot, Israel) ; Stavi, D. S. (Kaplan Medical Centre, Rehovot, Israel) ; Adi, N. A. (Kaplan Medical Centre, Rehovot, Israel) ; Poropat, T. (Rihard Knafelj, Ljubljana, Slovenia) ; Knafelj, R. (Rihard Knafelj, Ljubljana, Slovenia) ; Llopart, E. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Batlle, M. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; de Haro, Candelaria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Mesquida, J. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Pavlovic, D. (Dalhousie University, Halifax, Canada) ; Lewerentz, L. (Ernst-Moritz-Arndt-Universität, Greifswald, Germany) ; Spassov, A. (Ernst-Moritz-Arndt-Universität, Greifswald, Germany) ; Schneider, R. (Ernst-Moritz-Arndt-Universität, Greifswald, Germany) ; De Smet, S. (Ghent University Hospital. (Bèlgica)) ; De Raedt, S. (Ghent University Hospital. (Bèlgica)) ; Derom, E. (Ghent University Hospital. (Bèlgica)) ; Depuydt, Pieter (Ghent University Hospital. (Bèlgica)) ; Oeyen, S. (Ghent University Hospital. (Bèlgica)) ; Benoit, D. (Ghent University Hospital. (Bèlgica)) ; Decruyenaere, J. (Ghent University Hospital. (Bèlgica)) ; Gobatto, A. (Universidade de São Paulo, São Paulo, Brazil) ; Besen, B. (Universidade de São Paulo, São Paulo, Brazil) ; Tierno, P. (Universidade de São Paulo, São Paulo, Brazil) ; Melro, L. (Universidade de São Paulo, São Paulo, Brazil) ; Mendes, P. (Universidade de São Paulo, São Paulo, Brazil) ; Cadamuro, F. (Universidade de São Paulo, São Paulo, Brazil) ; Park, M. (Universidade de São Paulo, São Paulo, Brazil) ; Malbouisson, L. M. (Universidade de São Paulo, São Paulo, Brazil) ; Civantos, B. C. (Hospital Universitario La Paz (Madrid)) ; Lopez, J. L. (Hospital Universitario La Paz (Madrid)) ; Robles, A. (Hospital Universitario La Paz (Madrid)) ; Figueira, J. (Hospital Universitario La Paz (Madrid)) ; Yus, S. (Hospital Universitario La Paz (Madrid)) ; Garcia, A. (Hospital Universitario La Paz (Madrid)) ; Oglinda, A. (Institute of Mother and Child, Chisinau mun., Moldova) ; Ciobanu, G. (Institute of Emergency Medicine, Chisinau mun., Moldova) ; Oglinda, C. (Institute of Mother and Child, Chisinau mun., Moldova) ; Schirca, L. (Institute of Mother and Child, Chisinau mun., Moldova) ; Sertinean, T. (Institute of Mother and Child, Chisinau mun., Moldova) ; Lupu, V. (State University of Medicine and Pharmacy, Chisinau mun., Moldova) ; Kelly, P. (Aerogen, Galway, Ireland) ; O'Sullivan, A. (Aerogen, Galway, Ireland) ; Sweeney, L. (Aerogen, Galway, Ireland) ; MacLoughlin, R. (Aerogen, Galway, Ireland) ; O'Sullivan, A. (Aerogen, Galway, Ireland) ; Kelly, P. (Aerogen, Galway, Ireland) ; Sweeney, L. (Aerogen, Galway, Ireland) ; Mukeria, E. (Aerogen, Galway, Ireland) ; Wolny, M. (Aerogen, Galway, Ireland) ; MacLoughlin, R. (Aerogen, Galway, Ireland) ; Pagano, A. (Cardarelli Hospital, Naples, Italy) ; Numis, F. (San Paolo Hospital, Naples, Italy) ; Visone, G. (Cardarelli Hospital, Naples, Italy) ; Saldamarco, L. (Cardarelli Hospital, Naples, Italy) ; Russo, T. (Cardarelli Hospital, Naples, Italy) ; Porta, G. (San Paolo Hospital, Naples, Italy) ; Paladino, F. (Cardarelli Hospital, Naples, Italy) ; Bell, C. (National University of Ireland, Galway, Galway City, Ireland) ; Liu, Junfeng (Mount Sinai Hospital, Toronto, Canada) ; Debacker, J. (Mount Sinai Hospital, Toronto, Canada) ; Lee, C. (Mount Sinai Hospital, Toronto, Canada) ; Tamberg, E. (Mount Sinai Hospital, Toronto, Canada) ; Campbell, V. (Mount Sinai Hospital, Toronto, Canada) ; Mehta, Sangeeta (Mount Sinai Hospital, Toronto, Canada) ; Silva-Pinto, A. (Centro Hospitalar São João, Porto, Portugal) ; Sarmento, A. (Centro Hospitalar São João, Porto, Portugal) ; Santos, L. (Centro Hospitalar São João, Porto, Portugal) ; Kara, Ý. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Yýldýrým, F. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Zerman, A. (Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey) ; Güllü, Z. (Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey) ; Boyacý, N. (Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey) ; Basarýk Aydogan, B. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Gaygýsýz, Ü. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Gönderen, K. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Arýk, G. (Gazi University School of Medicine, Geriatrics Department, Ankara, Turkey) ; Turkoglu, M. (Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey) ; Aydogdu, M. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Aygencel, G. (Gazi University School of Medicine, Internal Medicine Critical Care Department, Ankara, Turkey) ; Ülger, Z. (Gazi University School of Medicine, Geriatrics Department, Ankara, Turkey) ; Gursel, G. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Boyacý, N. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Isýkdogan, Z. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Özdedeoglu, Ö. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Güllü, Z. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Badoglu, M. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Gaygýsýz, U. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Aydogdu, M. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Gursel, G. (Gazi University School of Medicine Respiratory Medicine and Critical Care Department, Ankara, Turkey) ; Kongpolprom, N. (Chulalongkorn University, Bangkok, Thailand) ; Sittipunt, C. (Chulalongkorn University, Bangkok, Thailand) ; Eden, A. (Carmel, Lady Davis Medical Center, Haifa, Israel) ; Kokhanovsky, Y. (Carmel, Lady Davis Medical Center, Haifa, Israel) ; Bursztein - De Myttenaere, S. (Carmel, Lady Davis Medical Center, Haifa, Israel) ; Pizov, R. (Carmel, Lady Davis Medical Center, Haifa, Israel) ; Neilans, L. (Duke University, Durham, USA) ; MacIntyre, N. (Duke University, Durham, USA) ; Radosevich, M. (Mayo Clinic, Rochester, USA) ; Wanta, B. (Mayo Clinic, Rochester, USA) ; Weber, V. (Mayo Clinic, Rochester, USA) ; Meyer, T. (Mayo Clinic, Rochester, USA) ; Smischney, N. (Mayo Clinic, Rochester, USA) ; Brown, D. (Mayo Clinic, Rochester, USA) ; Diedrich, D. (Mayo Clinic, Rochester, USA) ; Fuller, A. (St Helens and Knoowsley, Prescot, UK) ; McLindon, P. (Royal Infirmary, Edinburgh, UK) ; Sim, K. (St Helens and Knoowsley, Prescot, UK) ; Shoaeir, M. (Alexandria Universitry General Hospital, Alexandria, Egypt) ; Noeam, K. (Alexandria Universitry General Hospital, Alexandria, Egypt) ; Mahrous, A. (Alexandria Universitry General Hospital, Alexandria, Egypt) ; Matsa, R. (University Hospital North Middlands, Stoke On Trent, UK) ; Ali, A. (Alexandria Universitry General Hospital, Alexandria, Egypt) ; Dridi, C. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Koubaji, S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Kamoun, S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Haddad, F. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Ben Souissi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Laribi, B. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Riahi, A. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Mebazaa, M. S. (Mongi Slim University Hospital, La Marsa, Tunisia) ; Pérez-Calatayud, A. (Medica Sur, Mexico City, Mexico) ; Carrillo-Esper, R. (Medica Sur, Mexico City, Mexico) ; Zepeda-Mendoza, A. (Medica Sur, Mexico City, Mexico) ; Diaz-Carrillo, M. (Medica Sur, Mexico City, Mexico) ; Arch-Tirado, E. (Instituto Nacional de Rehabilitacion, Mexico City, Mexico) ; Carbognin, S. (University of Padua, Padua, Italy) ; Pelacani, L. (Sant Antony hospital, Padua, Italy) ; Zannoni, F. (University of Padua, Padua, Italy) ; Agnoli, A. (Sant Antony hospital, Padua, Italy) ; Gagliardi, G. (Sant Antony hospital, Padua, Italy) ; Cho, R. (HCMC, Minneapolis, USA) ; Adams, A. (HCMC, Minneapolis, USA) ; Lunos, S. (University of Minnesota, Minneapolis, USA) ; Ambur, S. (HCMC, Minneapolis, USA) ; Shapiro, R. (HCMC, Minneapolis, USA) ; Prekker, M. (HCMC, Minneapolis, USA) ; Thijssen, M. (Viecuri Medical Center, Venlo, Netherlands) ; Janssen, L. (Viecuri Medical Center, Venlo, Netherlands) ; Foudraine, N. (Viecuri Medical Center, Venlo, Netherlands) ; Voscopoulos, C. J. (University of Hawaii, John A. Burns School of Medicine, Honolulu, USA) ; Freeman, J. (Respiratory Motion Inc., Waltham, USA) ; Voscopoulos, C. J. (University of Hawaii, John A. Burns School of Medicine, Honolulu, USA) ; Freeman, J. (Respiratory Motion Inc., Waltham, USA) ; George, E. (Massachusetts General Hospital, Boston, USA) ; Voscopoulos, C. J. (University of Hawaii, John A. Burns School of Medicine, Honolulu, USA) ; Eversole, D. (Respiratory Motion Inc., Waltham, USA) ; Freeman, J. (Respiratory Motion Inc., Waltham, USA) ; George, E. (Massachusetts General Hospital, Boston, USA) ; Muttini, S. (AO Desio e Vimercate, Vimercate, Italy) ; Bigi, R. (AO Desio e Vimercate, Vimercate, Italy) ; Villani, G. (AO Crema, Crema, Italy) ; Patroniti, N. (University of Milan-Bicocca, Monza, Italy) ; Williams, G. (UT Health Science Center at Houston, Houston, TX USA) ; Voscopoulos, C. J. (University of Hawaii, John A. Burns School of Medicine, Honolulu, HI USA) ; Freeman, J. (Respiratory Motion Inc., Waltham, MA USA) ; George, E. (Massachusetts General Hospital (Boston)) ; Waldmann, A. (Swisstom AG, Landquart, Switzerland) ; Böhm, S. (Swisstom AG, Landquart, Switzerland) ; Windisch, W. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten / Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Strassmann, S. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten / Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Karagiannidis, C. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten / Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Waldmann, A. (Swisstom AG, Landquart, Switzerland) ; Böhm, S. (Massachusetts General Hospital (Boston)) ; Windisch, W. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten/ Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Strassmann, S. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten/ Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Karagiannidis, C. (Kliniken der Stadt Köln, Pneumology and Critical Care Medicine, Witten/ Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, Germany) ; Karagiannidis, C. K. (ARDS and ECMO Center Köln-Merheim, Cologne, Germany) ; Waldmann, A. W. (Swisstom, Chur, Switzerland) ; Böhm, S (Swisstom, Chur, Switzerland) ; Strassmann, S. (ARDS and ECMO Center Köln-Merheim, Cologne, Germany) ; Windisch, W. W. (ARDS and ECMO Center Köln-Merheim, Cologne, Germany) ; Persson, P. (Sahlgrenska University Hospital (Suècia)) ; Lundin, S. (Sahlgrenska University Hospital (Suècia)) ; Stenqvist, O. (Sahlgrenska University Hospital (Suècia)) ; Porta, G. (Second University of Naples, Naples, Italy) ; Numis, F. (San Paolo Hospital, Naples, Italy) ; Serra, C. S. (University of Sassari, Sassari, Italy) ; Pagano, A. P. (Cardarelli Hospital, Naples, Italy) ; Masarone, M. M. (University of Saerno, Salerno, Italy) ; Rinaldi, L. R. (Second University of Naples, Naples, Italy) ; Amelia, A. A. (Second University of Naples, Naples, Italy) ; Fascione, M. F. (Second University of Naples, Naples, Italy) ; Adinolfi, L. A. (Second University of Naples, Naples, Italy) ; Ruggiero, E. R. (San Paolo Hospital, Naples, Italy) ; Asota, F. (East Surrey Hospital, Surrey and Sussex NHS Trust, Surrey, UK) ; O'Rourke, K. (East Surrey Hospital, Surrey and Sussex NHS Trust, Surrey, UK) ; Ranjan, S. (East Surrey Hospital, Surrey and Sussex NHS Trust, Surrey, UK) ; Morgan, P. (East Surrey Hospital, Surrey and Sussex NHS Trust, Surrey, UK) ; DeBacker, J. W. (Mount Sinai Hospital (Toronto, Canadà)) ; Tamberg, E. (Mount Sinai Hospital (Toronto, Canadà)) ; O'Neill, L. (Mount Sinai Hospital (Toronto, Canadà)) ; Munshi, L. (Mount Sinai Hospital (Toronto, Canadà)) ; Burry, L. (Mount Sinai Hospital (Toronto, Canadà)) ; Fan, E. (University Health Network-Toronto General Hospital and Univeristy of Toronto, Toronto, Canada) ; Mehta, Sangeeta (Mount Sinai Hospital (Toronto, Canadà)) ; Poo, S. (University of Cambridge, Cambridge, UK) ; Mahendran, K. (Papworth Hospital, Cambridge, UK) ; Fowles, J. (Papworth Hospital, Cambridge, UK) ; Gerrard, C. (Papworth Hospital, Cambridge, UK) ; Vuylsteke, A. (Papworth Hospital, Cambridge, UK) ; Loveridge, R. (King's College Hospital NHS Foundation Trust) ; Chaddock, C. (King's College Hospital NHS Foundation Trust) ; Patel, S. (King's College Hospital NHS Foundation Trust) ; Kakar, V. (King's College Hospital NHS Foundation Trust) ; Willars, C. (King's College Hospital NHS Foundation Trust) ; Hurst, T. (King's College Hospital NHS Foundation Trust) ; Park, C. (King's College Hospital NHS Foundation Trust) ; Best, T. (King's College Hospital NHS Foundation Trust) ; Vercueil, A. (King's College Hospital NHS Foundation Trust) ; Auzinger, G. (King's College Hospital NHS Foundation Trust) ; Borgman, A. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Proudfoot, A. G. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Grins, E. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Emiley, K. E. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Schuitema, J. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Fitch, S. J. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Marco, G. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Sturgill, J. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Dickinson, M. G. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Strueber, M. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Khaghani, A. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Wilton, P. (Meijer Heart & Vascular Institute, Grand Rapids, USA) ; Jovinge, S. M. ; Sampson, C. (Glenfield Hospital, UHL, Leicester, UK) ; Harris-Fox, S. (Glenfield Hospital, UHL, Leicester, UK) ; Cove, M. E. (National University Hospital, Singapore, Singapore) ; Vu, L. H. (National University Singapore, Singapore, Singapore) ; Sen, A. (Mayo Clinic, Phoenix, AZ USA) ; Federspiel, W. J. (University of Pittsburgh, Pittsburgh, PA USA) ; Kellum, J. A. (University of Pittsburgh, Pittsburgh, PA USA) ; Mazo Torre, C. (Hospital Universitari Vall d'Hebron) ; Riera, J. (Hospital Universitari Vall d'Hebron) ; Ramirez, S. (Hospital Universitari Vall d'Hebron) ; Borgatta, Barbara (Hospital Universitari Vall d'Hebron) ; Lagunes, Leonel (Hospital Universitari Vall d'Hebron) ; Rello, J. (Universitat Autònoma de Barcelona) ; Kuzovlev, A. K. (V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia) ; Moroz, V. (V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia) ; Goloubev, A. (V.A. Negovsky Research Institute of General Reanimatology, Moscow, Russia) ; Polovnikov, S. (NN Burdenko Main Military Hospital, Moscow, Russia) ; Nenchuk, S. (NN Burdenko Main Military Hospital, Moscow, Russia) ; Karavana, V. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Glynos, C. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Asimakos, A. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Pappas, K. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Vrettou, C. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Magkou, M. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Ischaki, E. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Stathopoulos, G. (University of Patras, Rio, Achaia Greece) ; Zakynthinos, S. (George P. Livanos and Marianthi Simou Laboratories, Athens, Greece) ; Spadaro, S. (University of Ferrara, Ferrara, Italy) ; Kozhevnikova, I. (University of Ferrara, Ferrara, Italy) ; Dalla Corte, F. (University of Ferrara, Ferrara, Italy) ; Grasso, S. (University of Bari, Bari, Italy) ; Casolari, P. (University of Ferrara, Ferrara, Italy) ; Caramori, G. (University of Ferrara, Ferrara, Italy) ; Volta, C. (University of Ferrara, Ferrara, Italy) ; Andrianjafiarinoa, T. (CHU HJRA, Antananarivo, Madagascar) ; Randriamandrato, T. (CHU HJRA, Antananarivo, Madagascar) ; Rajaonera, T. (CHU HJRA, Antananarivo, Madagascar) ; El-Dash, S. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Costa, E. L. V. (Cardio-Pulmonary Department, Pulmonary Division, Heart Institute (Incor), University of São Paulo, São Paulo, Brazil) ; Tucci, M. R. (Cardio-Pulmonary Department, Pulmonary Division, Heart Institute (Incor), University of São Paulo, São Paulo, Brazil) ; Leleu, F. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Kontar, L. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; De Cagny, B. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Brazier, F. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Titeca, D. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Bacari-Risal, G. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Maizel, J. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Amato, Maria Pia (Cardio-Pulmonary Department, Pulmonary Division, Heart Institute (Incor), University of São Paulo, São Paulo, Brazil) ; Slama, M. (Réanimation médicale, Centre Hospitalier Universitaire, Amiens, France) ; Mercado, P. (CHU Amiens, Amiens, France) ; Maizel, J. (CHU Amiens, Amiens, France) ; Kontar, L. (CHU Amiens, Amiens, France) ; Titeca, D. (CHU Amiens, Amiens, France) ; Brazier, F. (CHU Amiens, Amiens, France) ; Riviere, A. (CHU Amiens, Amiens, France) ; Joris, M. (CHU Amiens, Amiens, France) ; Soupison, T. (CHU Amiens, Amiens, France) ; De Cagny, B. (CHU Amiens, Amiens, France) ; El Dash, S. (CHU Amiens, Amiens, France) ; Slama, M. (CHU Amiens, Amiens, France) ; Remmington, A. (Royal Brompton Hospital (Londres)) ; Fischer, A. (Royal Brompton Hospital (Londres)) ; Squire, S. (Royal Brompton Hospital (Londres)) ; Boichat, M. (Royal Brompton Hospital (Londres)) ; Honzawa, H. (Musashino Red Cross Hospital, Tokyo, Japan) ; Yasuda, H. (Musashino Red Cross Hospital, Tokyo, Japan) ; Adati, T. (Musashino Red Cross Hospital, Tokyo, Japan) ; Suzaki, S. (Musashino Red Cross Hospital, Tokyo, Japan) ; Horibe, M. (JSEPTIC Clinical Trial Group, Tokyo, Japan) ; Sasaki, M. (JSEPTIC Clinical Trial Group, Tokyo, Japan) ; Sanui, M. (JSEPTIC Clinical Trial Group, Tokyo, Japan) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Daniel, J. (Centro Hospitalar do Porto, Porto, Portugal) ; Miranda, H. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, A. ; Milinis, K. (University of Liverpool, Liverpool, UK) ; Cooper, M. (Royal Liverpool University Hospital, Liverpool, UK) ; Williams, G. R. (Royal Liverpool University Hospital, Liverpool, UK) ; McCarron, E. (Royal Liverpool University Hospital, Liverpool, UK) ; Simants, S. (Royal Liverpool University Hospital, Liverpool, UK) ; Patanwala, I. (Royal Liverpool University Hospital, Liverpool, UK) ; Welters, I. (University of Liverpool, Liverpool, UK) ; Su, Y. (Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi County, Taiwan) ; Fernández Villanueva, J. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Fernández Garda, R. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; López Lago, A. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Rodríguez Ruíz, E. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Hernández Vaquero, R. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Tomé Martínez de Rituerto, S. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Varo Pérez, E. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Lefel, N. (MUMC, Maastricht, Netherlands) ; Schaap, F. (MUMC, Maastricht, Netherlands) ; Bergmans, D. (MUMC, Maastricht, Netherlands) ; Olde Damink, S. (MUMC, Maastricht, Netherlands) ; Van de Poll, M. (MUMC, Maastricht, Netherlands) ; Tizard, K. (Royal Liverpool University Hospital, Liverpool, UK) ; Lister, C. (Royal Liverpool University Hospital, Liverpool, UK) ; Poole, L. (Royal Liverpool University Hospital, Liverpool, UK) ; Ringaitiene, D. (Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania) ; Gineityte, D. (Vilnius University, Faculty of Medicine, Vilnius, Lithuania) ; Vicka, V. (Vilnius University, Faculty of Medicine, Vilnius, Lithuania) ; Norkiene, I. (Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania) ; Sipylaite, J. (Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania) ; O'Loughlin, A. (Mercy University Hospital, Cork, Ireland) ; Maraj, V. (Mercy University Hospital, Cork, Ireland) ; Dowling, J. (Mercy University Hospital, Cork, Ireland) ; Velasco, M. B. (Hospital Meridional S.A., Cariacica, Brazil) ; Dalcomune, D. M. (Hospital Meridional S.A., Cariacica, Brazil) ; Dias, E. B. (Hospital Meridional S.A., Cariacica, Brazil) ; Fernandes, S. L. (Hospital Meridional S.A., Cariacica, Brazil) ; Oshima, T. (Geneva University Hospitals (Suïssa)) ; Graf, S. (Geneva University Hospitals (Suïssa)) ; Heidegger, C. (Geneva University Hospitals (Suïssa)) ; Genton, L. (Geneva University Hospitals (Suïssa)) ; Karsegard, V. (Geneva University Hospitals (Suïssa)) ; Dupertuis, Y. (Geneva University Hospitals (Suïssa)) ; Pichard, C. (Geneva University Hospitals (Suïssa)) ; Friedli, N. (Medical University Department, Kantonsspital Aarau, Aarau, Switzerland) ; Stanga, Z. (Bern University Hospital) ; Mueller, B. (Medical University Department, Kantonsspital Aarau, Aarau, Switzerland) ; Schuetz, P. (Medical University Department, Kantonsspital Aarau, Aarau, Switzerland) ; Vandersteen, L. (Jessa Ziekenhuis, Hasselt, Belgium) ; Stessel, B. (Jessa Ziekenhuis, Hasselt, Belgium) ; Evers, S. (Jessa Ziekenhuis, Hasselt, Belgium) ; Van Assche, A. (Jessa Ziekenhuis, Hasselt, Belgium) ; Jamaer, L. (Jessa Ziekenhuis, Hasselt, Belgium) ; Dubois, J. (Jessa Ziekenhuis, Hasselt, Belgium) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Castro, H. (Centro Hospitalar do Porto, Porto, Portugal) ; Moura, J. (Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal) ; Valente, J. (Unidade de Saude Local de Castelo Branco, Castelo Branco, Portugal) ; Martins, P. (Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal) ; Casteloes, P. (Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal) ; Magalhaes, C. (Centro Hospitalar do Algarve, Faro, Portugal) ; Cabral, S. (Instituto Portugues de Oncologia do Porto, Porto, Portugal) ; Santos, M. (Faculdade de Ciencias da Nutricao e Alimentacao da Universidade do Porto, Porto, Portugal) ; Oliveira, B. (Faculdade de Ciencias da Nutricao e Alimentacao da Universidade do Porto, Porto, Portugal) ; Salgueiro, A. (Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Santos, M. (Faculdade de Ciencias da Nutrição e Alimentação da Universidade do Porto, Porto, Portugal) ; Lafuente, E. (Centro Hospitalar Tamega e Sousa, Penafiel, Portugal) ; Castro, H. (Centro Hospitalar do Porto, Porto, Portugal) ; Cabral, S. (Instituto Português de Oncologia do Porto, Porto, Portugal) ; Moura, J. (Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal) ; Martins, P. (Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal) ; Oliveira, B. (Faculdade de Ciencias da Nutrição e Alimentação da Universidade do Porto, Porto, Portugal) ; Salgueiro, A. (Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal) ; Duarte, S. (Unidade de Saude Local de Castelo Branco, Castelo Branco, Portugal) ; Castro, S. (Centro Hospitalar do Algarve, Faro, Portugal) ; Melo, M. (Centro Hospitalar do Baixo Vouga, Aveiro, Portugal) ; Casteloes, P. (Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Gray, S. (Nottingham University Hospital NHS Trust, Nottingham, UK) ; Maipang, K. (Prince of Songkla University, Songkla, Thailand) ; Bhurayanontachai, R. (Prince of Songkla University, Songkla, Thailand) ; Grädel, L. G. (Kantonsspital Aarau, Aarau, Switzerland) ; Schütz, P. (Kantonsspital Aarau, Aarau, Switzerland) ; Langlois, P. (Université de Sherbrooke, Sherbrooke, Canada) ; Manzanares, W. (University Hospital, Montevideo, Uruguay) ; Tincu, R. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Cobilinschi, C. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Tomescu, D. (Fundeni Clinical Institute, Bucharest, Romania) ; Ghiorghiu, Z. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Macovei, R. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Manzanares, W. (University Hospital, Montevideo, Uruguay) ; Langlois, P. (Université de Sherbrooke, Sherbrooke, Canada) ; Lemieux, M. (Queen's University, Kingston, Canada) ; Elke, G. (University Medical Center Schleswig-Holstein, Kiel, Germany) ; Bloos, F. (University of Jena, Jena, Germany) ; Reinhart, Konrad (University of Jena, Jena, Germany) ; Heyland, D. (Queen's University, Kingston, Canada) ; Langlois, P. (Université de Sherbrooke, Sherbrooke, Canada) ; Lemieux, M. (Queen's University, Kingston, Canada) ; Aramendi, I. (University Hospital, Montevideo, Uruguay) ; Heyland, D. (Queen's University, Kingston, Canada) ; Manzanares, W. (University Hospital, Montevideo, Uruguay) ; Su, Y. (Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi County, Taiwan) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Babo, N. (Centro Hospitalar do Porto, Porto, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Hoshino, M. (Aida Hospital, Fukushima, Japan) ; Haraguchi, Y. (Keiyo Hospital, Tokyo, Japan) ; Kajiwara, S. (Aida Hospital, Fukushima, Japan) ; Mitsuhashi, T. (Shisei Hospital, Saitama, Japan) ; Tsubata, T. (Keiyo Hospital, Tokyo, Japan) ; Aida, M. (Aida Hospital, Fukushima, Japan) ; Rattanapraphat, T. (Prince of Songkla University, Hat Yai City, Songkhla Province Thailand) ; Bhurayanontachai, R. (Prince of Songkla University, Hat Yai City, Songkhla Province Thailand) ; Kongkamol, C. (Prince of Songkla University, Hat Yai City, Songkhla Province Thailand) ; Khwannimit, B. (Prince of Songkla University, Hat Yai City, Songkhla Province Thailand) ; Marinho, R. (Centro Hospitalar do Porto, Porto, Portugal) ; Santos, M. (Faculdade de Ciencias da Nutrição e Alimentação da Universidade do Porto, Porto, Portugal) ; Castro, H. (Centro Hospitalar do Porto, Porto, Portugal) ; Lafuente, E. (Centro Hospitalar Tamega e Sousa, Penafiel, Portugal) ; Salgueiro, A. (Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal) ; Cabral, S. (Instituto Português de Oncologia do Porto, Porto, Portugal) ; Martins, P. (Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal) ; Moura, J. (Unidade Local de Saude do Alto Minho, Viana do Castelo, Portugal) ; Oliveira, B. (Faculdade de Ciencias da Nutrição e Alimentação da Universidade do Porto, Porto, Portugal) ; Melo, M. (Centro Hospitalar Baixo Vouga, Aveiro, Portugal) ; Xavier, B. (Centro Hospitalar Baixo Vouga, Aveiro, Portugal) ; Valente, J. (Unidade de Saude Local de Castelo Branco, Castelo Branco, Portugal) ; Magalhaes, C. (Centro Hospitalar do Algarve, Faro, Portugal) ; Casteloes, P. (Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal) ; Marinho, A. (Centro Hospitalar do Porto, Porto, Portugal) ; Moisidou, D. (Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece) ; Ampatzidou, F. (Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece) ; Koutsogiannidis, C. (Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece) ; Moschopoulou, M. (Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece) ; Drossos, G. (Department of Cardiothoracic Surgery, George Papanikolaou General Hospital, Thessaloniki, Greece) ; Taskin, G. (Gülhane Military Medical Academy, Ankara, Turkey) ; Çakir, M. (Gülhane Military Medical Academy, Ankara, Turkey) ; Güler, A. K. (Gülhane Military Medical Academy, Ankara, Turkey) ; Taskin, A. (Ankara Mevki Military Hospital, Ankara, Turkey) ; Öcal, N. (Gülhane Military Medical Academy, Ankara, Turkey) ; Özer, S. (Gülhane Military Medical Academy, Ankara, Turkey) ; Yamanel, L. (Gülhane Military Medical Academy, Ankara, Turkey) ; Wong, J. M. (St Bartholomew's Hospital (Regne Unit)) ; Fitton, C. (St Bartholomew's Hospital (Regne Unit)) ; Anwar, S. (St Bartholomew's Hospital (Regne Unit)) ; Stacey, S. (St Bartholomew's Hospital (Regne Unit)) ; Aggou, M. (Aristotle Medical School, Thessaloniki, Greece) ; Fyntanidou, B. (Aristotle Medical School, Thessaloniki, Greece) ; Patsatzakis, S. (Aristotle Medical School, Thessaloniki, Greece) ; Oloktsidou, E. (Aristotle Medical School, Thessaloniki, Greece) ; Lolakos, K. (Aristotle Medical School, Thessaloniki, Greece) ; Papapostolou, E. (Aristotle Medical School, Thessaloniki, Greece) ; Grosomanidis, V. (Aristotle Medical School, Thessaloniki, Greece) ; Suda, S. (Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan) ; Ikeda, T. (Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan) ; Ono, S. (Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan) ; Ueno, T. (Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan) ; Izutani, Y. (Tokyo Medical University Hachiosi Medical Center, Tokyo, Japan) ; Gaudry, S. (Hôpital Louis Mourier, Colombes, France) ; Desailly, V. (Hôpital Louis Mourier, Colombes, France) ; Pasquier, P. (Laboratoire ILUMENS, Paris, France) ; Brun, P. B. (Institut de Hauts de Seine, Nanterre, France) ; Tesnieres, A. T. (Laboratoire ILUMENS, Paris, France) ; Ricard, J. D. (Hôpital Louis Mourier, Colombes, France) ; Dreyfuss, D. (Hôpital Louis Mourier, Colombes, France) ; Mignon, A. (Laboratoire ILUMENS, Paris, France) ; White, J. C. (University Hospital Lewisham, London, UK) ; Molokhia, A. (University Hospital Lewisham, London, UK) ; Dean, A. (Queen Elizabeth Hospital, London, UK) ; Stilwell, A. (University Hospital Lewisham, London, UK) ; Friedlaender, G. (Minet Green Health Practice, London, UK) ; Peters, M. (Department of Public Health, University of Liège, Liège, Belgium) ; Stipulante, S. (Department of Public Health, University of Liège, Liège, Belgium) ; Delfosse, A. (Department of Emergency Medicine, University Hospital of Liège, Liège, Belgium) ; Donneau, A. F. (Department of Medical Biostatistics, University of Liège, Liège, Belgium) ; Ghuysen, A. (Department of Public Health, University of Liège, Liège, Belgium) ; Feldmann, C. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Freitag, D. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Dersch, W. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Irqsusi, M. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Eschbach, D. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Steinfeldt, T. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Wulf, H. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Wiesmann, T. (University Hospital, Philipps University Marburg, Marburg, Germany) ; Kongpolprom, N. (Chulalongkorn University, Bangkok, Thailand) ; Cholkraisuwat, J. (Chulalongkorn University, Bangkok, Thailand) ; Beitland, S. (Oslo University Hospital (Oslo, Noruega)) ; Nakstad, E. (Oslo University Hospital (Oslo, Noruega)) ; Stær-Jensen, H. (Oslo University Hospital (Oslo, Noruega)) ; Drægni, T. (Oslo University Hospital (Oslo, Noruega)) ; Andersen, G. (Oslo University Hospital (Oslo, Noruega)) ; Jacobsen, D. (Oslo University Hospital (Oslo, Noruega)) ; Brunborg, C. (Oslo University Hospital (Oslo, Noruega)) ; Waldum-Grevbo, B. (Oslo University Hospital (Oslo, Noruega)) ; Sunde, K. (Oslo University Hospital (Oslo, Noruega)) ; Hoyland, K. (William Harvey Hospital, Ashford, UK) ; Pandit, D. (William Harvey Hospital, Ashford, UK) ; Hayakawa, K. (Kansai Medical University Takii Hospital, Moriguchi, Japan) ; Oloktsidou, E. (Aristotle Medical School, Thessaloniki, Greece) ; Kotzampassi, K. (Aristotle Medical School, Thessaloniki, Greece) ; Fyntanidou, B. (Aristotle Medical School, Thessaloniki, Greece) ; Patsatzakis, S. (Aristotle Medical School, Thessaloniki, Greece) ; Loukipoudi, L. (Aristotle Medical School, Thessaloniki, Greece) ; Doumaki, E. (Aristotle Medical School, Thessaloniki, Greece) ; Grosomanidis, V. (Aristotle Medical School, Thessaloniki, Greece) ; Yasuda, H. (Japanese Red Cross Musashino Hospital, Tokyo, Japan) ; Admiraal, M. M. (Academic Medical Center, Amsterdam, Netherlands) ; Van Assen, M. (Academic Medical Center, Amsterdam, Netherlands) ; Van Putten, M. J. (Medisch Spectrum Twente, Enschede, Netherlands) ; Tjepkema-Cloostermans, M. (Medisch Spectrum Twente, Enschede, Netherlands) ; Van Rootselaar, A. F. (Academic Medical Center, Amsterdam, Netherlands) ; Horn, J. (Academic Medical Center, Amsterdam, Netherlands) ; Ragusa, F. (University Modena, Modena, Italy) ; Marudi, A. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Baroni, S. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Gaspari, A. (University Modena, Modena, Italy) ; Bertellini, E. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Taha, A. (Faculty of Medicine Alexandria University, Alexandria, Egypt) ; Abdullah, T. (Faculty of Medicine Alexandria University, Alexandria, Egypt) ; Abdel Monem, S. (Faculty of Medicine Alexandria University, Alexandria, Egypt) ; Alcorn, S. (Victoria Hospital, Kirkcaldy, UK) ; McNeill, S. (Victoria Hospital, Kirkcaldy, UK) ; Russell, S. (Victoria Hospital, Kirkcaldy, UK) ; Eertmans, W. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; Genbrugge, C. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; Meex, I. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; Dens, J. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; Jans, F. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; De Deyne, C. (Ziekenhuis Oost-Limburg, Genk, Belgium) ; Cholkraisuwat, J. (Chulalongkorn University, Bangkok, Thailand) ; Kongpolprom, N. (Chulalongkorn University, Bangkok, Thailand) ; Avard, B. (The Canberra Hospital, Hughes, ACT Australia) ; Burns, R. (ANU Medical School, Canberra, Australia) ; Patarchi, A. ("Spirito Santo" Hospital, Pescara, Italy) ; Spina, T. ("Spirito Santo" Hospital, Pescara, Italy) ; Tanaka, H. (St Lukes International Hospital, Akashi-Chou Chuo-Ku, Japan) ; Otani, N. (St Lukes International Hospital, Akashi-Chou Chuo-Ku, Japan) ; Ode, S. (St Lukes International Hospital, Akashi-Chou Chuo-Ku, Japan) ; Ishimatsu, S. (St Lukes International Hospital, Akashi-Chou Chuo-Ku, Japan) ; Cho, J. (Kangwon National University, Chuncheonsi, South Korea) ; Moon, J. B. (Kangwon National University, Chuncheonsi, South Korea) ; Park, C. W. (Kangwon National University, Chuncheonsi, South Korea) ; Ohk, T. G. (Kangwon National University, Chuncheonsi, South Korea) ; Shin, M. C. (Kangwon National University, Chuncheonsi, South Korea) ; Won, M. H. (Kangwon National University, Chuncheonsi, South Korea) ; Dakova, S. (Military Medical Academy, Sofia, Bulgaria) ; Ramsheva, Z. (Military Medical Academy, Sofia, Bulgaria) ; Ramshev, K. (Military Medical Academy, Sofia, Bulgaria) ; Cho, J. (Kangwon National University, Chuncheonsi, South Korea) ; Moon, J. B. (Kangwon National University, Chuncheonsi, South Korea) ; Park, C. W. (Kangwon National University, Chuncheonsi, South Korea) ; Ohk, T. G. (Kangwon National University, Chuncheonsi, South Korea) ; Shin, M. C. (Kangwon National University, Chuncheonsi, South Korea) ; Cho, J. (Kangwon National University, Chuncheonsi, South Korea) ; Moon, J. B. (Kangwon National University, Chuncheonsi, South Korea) ; Park, C. W. (Kangwon National University, Chuncheonsi, South Korea) ; Ohk, T. G. (Kangwon National University, Chuncheonsi, South Korea) ; Shin, M. C. (Kangwon National University, Chuncheonsi, South Korea) ; Marudi, A. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Baroni, S. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Gaspari, A. (University Modena, Modena, Italy) ; Bertellini, E. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Orhun, G. (Istanbul University, Medical Faculty of Istanbul, Anesthesiology and Intensive Care, Istanbul, Turkey) ; Senturk, E. (Istanbul University, Medical Faculty of Istanbul, Anesthesiology and Intensive Care, Istanbul, Turkey) ; Ozcan, P. E. (Istanbul University, Medical Faculty of Istanbul, Anesthesiology and Intensive Care, Istanbul, Turkey) ; Sencer, S. (Istanbul University, Medical Faculty of Istanbul, Department of Neuroradiology, Istanbul, Turkey) ; Ulusoy, C. (Istanbul University, Institute of Experimental Medicine, Neuroscience, Istanbul, Turkey) ; Tuzun, E. (Istanbul University, Institute of Experimental Medicine, Neuroscience, Istanbul, Turkey) ; Esen, F. (Istanbul University, Medical Faculty of Istanbul, Anesthesiology and Intensive Care, Istanbul, Turkey) ; Tincu, R. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Cobilinschi, C. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Tomescu, D. (Fundeni Clinical Institute, Bucharest, Romania) ; Ghiorghiu, Z. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Macovei, R. (Bucharest Clinical Emergency Hospital, Bucharest, Romania) ; Van Assen, M. (Academic Medical Center, Amsterdam, Netherlands) ; Admiraal, M. M. (Academic Medical Center, Amsterdam, Netherlands) ; Van Putten, M. J. (Medisch Spectrum Twente, Enschede, Netherlands) ; Tjepkema-Cloostermans, M. (Medisch Spectrum Twente, Enschede, Netherlands) ; Van Rootselaar, A. F. (Academic Medical Center, Amsterdam, Netherlands) ; Horn, J. (Academic Medical Center, Amsterdam, Netherlands) ; Fallenius, M. (Helsinki University Hospital (Finlàndia)) ; Skrifvars, M. B. (Helsinki University Hospital (Finlàndia)) ; Reinikainen, M. (North Karelia Central Hospital, Joensuu, Finland) ; Bendel, S. (Kuopio University Hospital ( Finlàndia)) ; Raj, R. (Helsinki University Hospital (Finlàndia)) ; Abu-Habsa, Mamoun (King's College Hospital NHS Foundation Trust) ; Hymers, C. (King's College Hospital NHS Foundation Trust) ; Borowska, A. (King's College Hospital NHS Foundation Trust) ; Sivadhas, H. (King's College Hospital NHS Foundation Trust) ; Sahiba, S. (King's College Hospital NHS Foundation Trust) ; Perkins, S. (King's College Hospital NHS Foundation Trust) ; Rubio, J. (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; Rubio, J. A. (Complejo Hospitalario Infanta Cristina (Badajoz)) ; Sierra, R. (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; English, S. (The Ottawa Hospital, Ottawa, Canada) ; Chasse, M. (Ulaval, Quebec City, Canada) ; Turgeon, A. (Ulaval, Quebec City, Canada) ; Lauzier, F. (Ulaval, Quebec City, Canada) ; Griesdale, D. (UBC, Vancouver, Canada) ; Garland, A. (UManitoba, Winnipeg, Canada) ; Fergusson, D. A (OHRI, Ottawa, Canada) ; Zarychanski, R. (UBC, Vancouver, Canada) ; Tinmouth, A. (OHRI, Ottawa, Canada) ; Van Walraven, C. (OHRI, Ottawa, Canada) ; Montroy, K. (OHRI, Ottawa, Canada) ; Ziegler, J. (UManitoba, Winnipeg, Canada) ; Dupont Chouinard, R. (Ulaval, Quebec City, Canada) ; Carignan, R. (Ulaval, Quebec City, Canada) ; Dhaliwal, A. (UBC, Vancouver, Canada) ; Lum, C. (OHRI, Ottawa, Canada) ; Sinclair, J. (OHRI, Ottawa, Canada) ; Pagliarello, G. (OHRI, Ottawa, Canada) ; McIntyre, L. (OHRI, Ottawa, Canada) ; English, S. (The Ottawa Hospital, Ottawa, Canada) ; Chasse, M. (Ulaval, Quebec City, Canada) ; Turgeon, A. (Ulaval, Quebec City, Canada) ; Lauzier, F. (Ulaval, Quebec City, Canada) ; Griesdale, D. (UBC, Vancouver, Canada) ; Garland, A. (UManitoba, Winnipeg, Canada) ; Fergusson, D. A (Ottawa Hospital Research Institute, Ottawa, Canada) ; Zarychanski, R. (UManitoba, Winnipeg, Canada) ; Tinmouth, A. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Van Walraven, C. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Montroy, K. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Ziegler, J. (UManitoba, Winnipeg, Canada) ; Dupont Chouinard, R. (Ulaval, Quebec City, Canada) ; Carignan, R. (Ulaval, Quebec City, Canada) ; Dhaliwal, A. (UBC, Vancouver, Canada) ; Lum, C. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Sinclair, J. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Pagliarello, G. (Ottawa Hospital Research Institute, Ottawa, Canada) ; McIntyre, L. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Groza, T. (Cliniques St Luc, Université catholique de Louvain, Brussels, Belgium) ; Moreau, N. (Cliniques St Luc, Université catholique de Louvain, Brussels, Belgium) ; Castanares-Zapatero, D. (Cliniques St Luc, Université catholique de Louvain, Brussels, Belgium) ; Hantson, P. (Cliniques St Luc, Université catholique de Louvain, Brussels, Belgium) ; Carbonara, M. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Ortolano, F. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Zoerle, Tommaso (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Magnoni, S. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Pifferi, S. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Conte, V. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy) ; Stocchetti, N. (Milan University, Milan, Italy) ; Carteron, L. (CHUV, Lausanne, Switzerland) ; Suys, T. (CHUV, Lausanne, Switzerland) ; Patet, C. (CHUV, Lausanne, Switzerland) ; Quintard, H. (CHU de Nice, Nice, France) ; Oddo, M. (CHUV, Lausanne, Switzerland) ; Rubio, J. A. (Complejo Hospitalario Infanta Cristina (Badajoz)) ; Rubio, J. (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; Sierra, R. (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; Spatenkova, V. (Regional Hospital, Liberec, Czech Republic) ; Pokorna, E. (Institute of Experimental Medicine, Prague, Czech Republic) ; Suchomel, P. (Regional Hospital, Liberec, Czech Republic) ; Ebert, N. (Hennepin County Medical Center, Minneapolis, USA) ; Jancik, J. (Hennepin County Medical Center, Minneapolis, USA) ; Rhodes, H. (Hennepin County Medical Center, Minneapolis, USA) ; Bylinski, T. (University of Glasgow, Glasgow, UK) ; Hawthorne, C. (Institute of Neurological Sciences, NHSGGC, Glasgow, UK) ; Shaw, M. (Department of Clinical Physics and Bioengineering, NHSGGC, Glasgow, UK) ; Piper, I. (Department of Clinical Physics and Bioengineering, NHSGGC, Glasgow, UK) ; Kinsella, J. (Academic Unit of Anaesthesia, Pain and Critical Care Medicine, University of Glasgow, Glasgow, UK) ; Kink, A. K. (Smartimplant Ltd., Tallinn, Estonia) ; Rätsep, I. R. (NEMC, Tallinn, Estonia) ; Boutin, A. (Universite Laval, Quebec, Canada) ; Moore, L. (Universite Laval, Quebec, Canada) ; Chasse, M. (Universite Laval, Quebec, Canada) ; Zarychanski, R. (University of Manitoba, Winnipeg, Canada) ; Lauzier, F. (Universite Laval, Quebec, Canada) ; English, S. (Ottawa Hospital Research Institute, Ottawa, Canada) ; McIntyre, L. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Lacroix, J. (Universite de Montreal, Montreal, Canada) ; Griesdale, D. (University of British Columbia, Vancouver, Canada) ; Lessard-Bonaventure, P. (Universite Laval, Quebec, Canada) ; Turgeon, A. F. (Universite Laval, Quebec, Canada) ; Boutin, A. (Universite Laval, Quebec, Canada) ; Moore, L. (Universite Laval, Quebec, Canada) ; Green, R. (Dalhousie University, Halifax, Canada) ; Lessard-Bonaventure, P. (Universite Laval, Quebec, Canada) ; Erdogan, M. (Dalhousie University, Halifax, Canada) ; Butler, M. (Dalhousie University, Halifax, Canada) ; Lauzier, F. (Universite Laval, Quebec, Canada) ; Chasse, M. (Universite Laval, Quebec, Canada) ; English, S. (Ottawa Hospital Research Institute, Ottawa, Canada) ; McIntyre, L. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Zarychanski, R. (University of Manitoba, Winnipeg, Canada) ; Lacroix, J. (Universite de Montreal, Montreal, Canada) ; Griesdale, D. (University of British Columbia, Vancouver, Canada) ; Desjardins, P. (Universite Laval, Quebec, Canada) ; Fergusson, D. A. (Ottawa Hospital Research Institute, Ottawa, Canada) ; Turgeon, A. F. (Universite Laval, Quebec, Canada) ; Goncalves, B. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Vidal, B. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Valdez, C. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Rodrigues, A. C. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Miguez, L. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Moralez, G. (Hospital Estadual Getulio Vargas, Rio de Janeiro, Brazil) ; Hong, T. (Yonsei University College of Medicine, Seoul, South Korea) ; Kutz, A. (Kantonsspital Aarau, Aarau, Switzerland) ; Hausfater, P. (Emergency Department, Groupe Hospitalier Pitié-Salpêtrière, Paris, France) ; Amin, D. (Morton Plant Hospital, Clearwater, USA) ; Struja, T. (Kantonsspital Aarau, Aarau, Switzerland) ; Haubitz, S. (Kantonsspital Aarau, Aarau, Switzerland) ; Huber, A. (Department of Laboratory Medicine, Kantonsspital Aarau, Aarau, Switzerland) ; Mueller, B. (Kantonsspital Aarau, Aarau, Switzerland) ; Schuetz, P. (Kantonsspital Aarau, Aarau, Switzerland) ; Brown, T. (Royal Cornwall Hospital Trust, Truro, UK) ; Collinson, J. (Royal Cornwall Hospital Trust, Truro, UK) ; Pritchett, C. (Royal Cornwall Hospital Trust, Truro, UK) ; Slade, T. (Royal Cornwall Hospital Trust, Truro, UK) ; Le Guen, M. (Manchester Royal Infirmary, Manchester, UK) ; Hellings, S. (Manchester Royal Infirmary, Manchester, UK) ; Ramsaran, R. (Manchester Royal Infirmary, Manchester, UK) ; Alsheikhly, A. (Hamad Medical Corporation, Doha, Qatar) ; Abe, Toshikazu (University of Tsukuba, Tsukuba Medical Center Hospital, Tsukuba, Japan) ; Kanapeckaite, L. (King's College Hospital NHS Foundation Trust) ; Abu-Habsa, Mamoun (King's College Hospital NHS Foundation Trust) ; Bahl, R. (King's College Hospital NHS Foundation Trust) ; Russell, M. Q. (Kent, Surrey & Sussex Air Ambulance Trust, Kent, UK) ; Real, K. J. (Prometheus Delta-Tech, Herefordshire, UK) ; Abu-Habsa, Mamoun (King's College Hospital NHS Foundation Trust) ; Lyon, R. M. (Kent, Surrey & Sussex Air Ambulance Trust, Kent, UK) ; Oveland, N. P. (Stavanger University Hospital, Stavanger, Norway) ; Penketh, J. (Royal United Hospital, Bath, UK) ; Mcdonald, M. (Royal United Hospital, Bath, UK) ; Kelly, F. (Royal United Hospital, Bath, UK) ; Alfafi, M. (Aseer Central Hospital, Abha, Saudi Arabia) ; Alsolamy, S. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia) ; Almutairi, W. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia) ; Alotaibi, B. (King Fahad Medical City, Riyadh, Saudi Arabia) ; Van den Berg, A. E. (HagaZiekenhuis, Den Haag, Netherlands) ; Schriel, Y. (Reinier de Graaf Gasthuis, Delft, Netherlands) ; Dawson, L. (Reinier de Graaf Gasthuis, Delft, Netherlands) ; Meynaar, I. A. (HagaZiekenhuis, Den Haag, Netherlands) ; Talaie, H. (Toxicological Research Center, Department of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran) ; Silva, D. (Santa Maria University Hospital, Lisboa, Portugal) ; Fernandes, S. (Santa Maria University Hospital, Lisboa, Portugal) ; Gouveia, J. (Santa Maria University Hospital, Lisboa, Portugal) ; Santos Silva, J. (Santa Maria University Hospital, Lisboa, Portugal) ; Foley, J. (St. Vincent's University Hospital, Dublin 4, Ireland) ; Kaskovagheorgescu, A. (St. Vincent's University Hospital, Dublin 4, Ireland) ; Evoy, D. (St. Vincent's University Hospital, Dublin 4, Ireland) ; Cronin, J. (St. Vincent's University Hospital, Dublin 4, Ireland) ; Ryan, J. (St. Vincent's University Hospital, Dublin 4, Ireland) ; Huck, M. (Percy Military Teaching Hospital, Clamart, France) ; Hoffmann, C. (Percy Military Teaching Hospital, Clamart, France) ; Renner, J. (Percy Military Teaching Hospital, Clamart, France) ; Laitselart, P. (Percy Military Teaching Hospital, Clamart, France) ; Donat, N. (Percy Military Teaching Hospital, Clamart, France) ; Cirodde, A. (Percy Military Teaching Hospital, Clamart, France) ; Schaal, J. V. (Percy Military Teaching Hospital, Clamart, France) ; Masson, Y. (Percy Military Teaching Hospital, Clamart, France) ; Nau, A. (Percy Military Teaching Hospital, Clamart, France) ; Leclerc, T. (Percy Military Teaching Hospital, Clamart, France) ; Howarth, O. (Whiston Hospital, Prescot, UK) ; Davenport, K. (Whiston Hospital, Prescot, UK) ; Jeanrenaud, P. (Whiston Hospital, Prescot, UK) ; Raftery, S. (Whiston Hospital, Prescot, UK) ; MacTavish, P. (Glasgow Royal Infirmary, Glasgow, UK) ; Devine, H. (Glasgow Royal Infirmary, Glasgow, UK) ; McPeake, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Daniel, M. (Glasgow Royal Infirmary, Glasgow, UK) ; Kinsella, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Quasim, T. (Glasgow Royal Infirmary, Glasgow, UK) ; Alrabiee, S. (King Abdulaziz Medical City, National Guard Hospital, Riyadh, Saudi Arabia) ; Alrashid, A. (Department of Management, College of Business Administration, King Saud University, Saudi Arabia, Riyadh, Saudi Arabia) ; Alsolamy, S. (King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia) ; Gundogan, O. (Ege University Hospital, Izmir, Turkey) ; Bor, C. (Ege University Hospital, Izmir, Turkey) ; Akýn Korhan, E. (Katip Celebi University, Health Sciences Faculty, Izmir, Turkey) ; Demirag, K. (Ege University Hospital, Izmir, Turkey) ; Uyar, M. (Ege University Hospital, Izmir, Turkey) ; Frame, F. (Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK) ; Ashton, C. (Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK) ; Bergstrom Niska, L. (Milton Keynes University Hospital NHS Foundation Trust, Milton Keynes, UK) ; Dilokpattanamongkol, P. (Faculty of Pharmacy, Mahidol University, Bangkok, Thailand) ; Suansanae, T. (Faculty of Pharmacy, Mahidol University, Bangkok, Thailand) ; Suthisisang, C. (Faculty of Pharmacy, Mahidol University, Bangkok, Thailand) ; Morakul, S. (Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ; Karnjanarachata, C. (Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ; Tangsujaritvijit, V. (Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand) ; Mahmood, S. (Specialist Anesthesia, Doha, Qatar) ; Al Thani, H. (Specialist Anesthesia, Doha, Qatar) ; Almenyar, A. (Specialist Anesthesia, Doha, Qatar) ; Vakalos, A. (Xanthi General Hospital, Xanthi, Greece) ; Avramidis, V. (Xanthi General Hospital, Xanthi, Greece) ; Sharvill, R. (Royal United Hospital, Bath, UK) ; Penketh, J. (Royal United Hospital, Bath, UK) ; Morton, S. E. (University of Canterbury, Christchurch, New Zealand) ; Chiew, Y. S. (University of Canterbury, Christchurch, New Zealand) ; Pretty, C. (University of Canterbury, Christchurch, New Zealand) ; Chase, J. G. (University of Canterbury, Christchurch, New Zealand) ; Shaw, G. M. (Christchurch Hospital, Christchurch, New Zealand) ; Knafelj, R. (Rihard Knafelj, Ljubljana, Slovenia) ; Kordis, P. (Clinical Center Ljubljana, Ljubljana, Slovenia) ; Patel, S. (The Royal Marsden Hospital, London, UK) ; Grover, V. (The Royal Marsden Hospital, London, UK) ; Kuchyn, I. (Bogomolets National Medical University, Kiev, Ukraine) ; Bielka, K. (Bogomolets National Medical University, Kiev, Ukraine) ; Aidoni, Z. (Aristotle Medical School, Thessaloniki, Greece) ; Grosomanidis, V. (Aristotle Medical School, Thessaloniki, Greece) ; Kotzampassi, K. (Aristotle Medical School, Thessaloniki, Greece) ; Stavrou, G. (Aristotle Medical School, Thessaloniki, Greece) ; Fyntanidou, B. (Aristotle Medical School, Thessaloniki, Greece) ; Patsatzakis, S. (Aristotle Medical School, Thessaloniki, Greece) ; Skourtis, C. (Aristotle Medical School, Thessaloniki, Greece) ; Lee, S. D. (Royal Liverpool Intensive Care Unit, Liverpool, UK) ; Williams, K. (Royal Liverpool Intensive Care Unit, Liverpool, UK) ; Weltes, I. D. (University of Liverpool, Liverpool, UK) ; Berhane, S. (Homerton University Hospital, London, UK) ; Arrowsmith, C. (Homerton University Hospital, London, UK) ; Peters, C. (Homerton University Hospital, London, UK) ; Robert, S. (Homerton University Hospital, London, UK) ; Caldas, J. (University of Sao Paulo, Sao Paulo, Brazil) ; Panerai, R. B. (University of Leicester, Leicester, UK) ; Robinson, T. G. (University of Leicester, Leicester, UK) ; Camara, L. (University of Sao Paulo, Sao Paulo, Brazil) ; Ferreira, G. (University of Leicester, Leicester, UK) ; Borg-Seng-Shu, E. (University of Sao Paulo, Sao Paulo, Brazil) ; De Lima Oliveira, M. (University of Sao Paulo, Sao Paulo, Brazil) ; Mian, N. C. (University of Sao Paulo, Sao Paulo, Brazil) ; Santos, L. (University of Sao Paulo, Sao Paulo, Brazil) ; Nogueira, R. (University of Sao Paulo, Sao Paulo, Brazil) ; Zeferino, S. P. (University of Sao Paulo, Sao Paulo, Brazil) ; Jacobsen Teixeira, M. (University of Sao Paulo, Sao Paulo, Brazil) ; Galas, F. (University of Sao Paulo, Sao Paulo, Brazil) ; Hajjar, L. A. (University of Sao Paulo, Sao Paulo, Brazil) ; Killeen, P. (King's College Hospital NHS Foundation Trust) ; McPhail, M. (King's College Hospital NHS Foundation Trust) ; Bernal, William (King's College Hospital NHS Foundation Trust) ; Maggs, J. (King's College Hospital NHS Foundation Trust) ; Wendon, J. (King's College Hospital NHS Foundation Trust) ; Hughes, T. (King's College Hospital NHS Foundation Trust) ; Taniguchi, L. U. (Research and Education Institute, Sao Paulo, Brazil) ; Siqueira, E. M. (Research and Education Institute, Sao Paulo, Brazil) ; Vieira Jr, J. M. (Research and Education Institute, Sao Paulo, Brazil) ; Azevedo, L. C. (Research and Education Institute, Sao Paulo, Brazil) ; Ahmad, A. N. (King's College Hospital NHS Foundation Trust) ; Abu-Habsa, Mamoun (King's College Hospital NHS Foundation Trust) ; Bahl, R. (King's College Hospital NHS Foundation Trust) ; Helme, E. (King's College Hospital NHS Foundation Trust) ; Hadfield, S. (King's College Hospital NHS Foundation Trust) ; Loveridge, R. (King's College Hospital NHS Foundation Trust) ; Shak, J. (Ipswich Hospital NHS Trust, England, UK, Ipswich, UK) ; Senver, C. (Ipswich Hospital NHS Trust, England, UK, Ipswich, UK) ; Howard-Griffin, R. (Ipswich Hospital NHS Trust, England, UK, Ipswich, UK) ; Wacharasint, P. (Phramongkutklao Hospital, Bangkok, Thailand) ; Fuengfoo, P. (Phramongkutklao Hospital, Bangkok, Thailand) ; Sukcharoen, N. (Phramongkutklao Hospital, Bangkok, Thailand) ; Rangsin, R. (Phramongkutklao College of Medicine, Bangkok, Thailand) ; Sbiti-Rohr, D. (Kantonsspital Aarau, Aarau, Switzerland) ; Schuetz, P. (Kantonsspital Aarau, Aarau, Switzerland) ; Na, H. (Pusan National University Hospital, Busan, South Korea) ; Song, S. (Pusan National University Hospital, Busan, South Korea) ; Lee, S. (Pusan National University Hospital, Busan, South Korea) ; Jeong, E. (Pusan National University Hospital, Busan, South Korea) ; Lee, K. (Pusan National University Hospital, Busan, South Korea) ; Cooper, M. (Royal Liverpool University Hospital, Liverpool, UK) ; Milinis, K. (University of Liverpool, Liverpool, UK) ; Williams, G. (University of Liverpool, Liverpool, UK) ; McCarron, E. (Royal Liverpool University Hospital, Liverpool, UK) ; Simants, S. (Royal Liverpool University Hospital, Liverpool, UK) ; Patanwala, I. (Royal Liverpool University Hospital, Liverpool, UK) ; Welters, I. D. (University of Liverpool, Liverpool, UK) ; Zoumpelouli, E. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Volakli, E. A. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Chrysohoidou, V. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Georgiou, S. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Charisopoulou, K. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Kotzapanagiotou, E. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Panagiotidou, V. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Manavidou, K. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Stathi, Z. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Sdougka, M. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Salahuddin, N. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; AlGhamdi, B. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Marashly, Q. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Zaza, K. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Sharshir, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Khurshid, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Ali, Z. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Malgapo, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Jamil, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Shafquat, A. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Shoukri, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Hijazi, M. (King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia) ; Abe, T. (The Jikei University School of Medicine, Tokyo, Japan) ; Uchino, S. (The Jikei University School of Medicine, Tokyo, Japan) ; Takinami, M. (The Jikei University School of Medicine, Tokyo, Japan) ; Rangel Neto, N. R. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Oliveira, S. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Reis, F. Q. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Rocha, F. A. (Albert Schweitzer State Hospital, Rio de Janeiro, Brazil) ; Moralez, G. (PPG Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil) ; Ebecken, K. (PPG Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil) ; Rabello, Ligia Sarmet Cunha Farah (PPG Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil) ; Lima, M. F. (Hospital Esperanca Recife, Recife, Brazil) ; Hatum, R. (Hospital Total Cor, Rio de Janeiro, Brazil) ; De Marco, F. V. (Hospital viValle, São José dos Campos, Brazil) ; Alves, A. (Hospital Rios DOr, Rio de Janeiro, Brazil) ; Pinto, J. E. (Hospital Norte DOr, Rio de Janeiro, Brazil) ; Godoy, M. (Hospital Esperanca Olinda, Olinda, Brazil) ; Brasil, P. E. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Bozza, F. A. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Salluh, J. I. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Soares, M. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Krinsley, J. (Stamford Hospital, Stamford, USA) ; Kang, G. (Stamford Hospital, Stamford, USA) ; Perry, J. (Darent Valley Hospital, Dartford, UK) ; Hines, H. (William Harvey Hospital, Ashford, UK) ; Wilkinson, K. M. (St James's University Hospital, Leeds, UK) ; Tordoff, C. (St James's University Hospital, Leeds, UK) ; Sloan, B. (St James's University Hospital, Leeds, UK) ; Bellamy, M. C. (St James's University Hospital, Leeds, UK) ; Moreira, E. (Hospital Maciel, Montevideo, Uruguay) ; Verga, F. (Hospital Maciel, Montevideo, Uruguay) ; Barbato, M. (Hospital Maciel, Montevideo, Uruguay) ; Burghi, Gastón (Hospital Maciel, Montevideo, Uruguay) ; Soares, M. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Silva, U. V. (Hospital de Cancer de Barretos, Barretos, Brazil) ; Azevedo, L. C. (Hospital Sírio Libanês, Sao Paulo, Brazil) ; Torelly, A. P. (Sta. Casa de Porto Alegre, Porto Alegre, Brazil) ; Kahn, J. M. (University of Pittsburgh Medical Center, Pittsburgh, USA) ; Angus, D. C. (University of Pittsburgh Medical Center, Pittsburgh, USA) ; Knibel, M. F. (Hospital Sao Lucas, Rio de Janeiro, Brazil) ; Brasil, P. E. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Bozza, F. A. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Salluh, J. I. (DOr Institute for Research and Education - IDOR, Rio de Janeiro, Brazil) ; Velasco, M. B. (Hospital Meridional S.A., Cariacica, Brazil) ; Dalcomune, D. M. (Hospital Meridional S.A., Cariacica, Brazil) ; Marshall, R. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Gilpin, T. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Tridente, A. (Whiston Hospital, St Helens & Knowsley, UK) ; Raithatha, A. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Mota, D. (Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal) ; Loureiro, B. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Dias, J. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Afonso, O. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Coelho, F. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Martins, A. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Faria, F. (Instituto Português de Oncologia Francisco Gil - Porto, Porto, Portugal) ; Al-Dorzi, H. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Al Orainni, H. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; AlEid, F. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Tlaygeh, H. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Itani, A. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Hejazi, A. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Arabi, Y. (King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ; Gaudry, S. (Hôpital Louis Mourier, Colombes, France) ; Messika, J. (Hôpital Louis Mourier, Colombes, France) ; Ricard, J. D. (Hôpital Louis Mourier, Colombes, France) ; Guillo, S. (Hôpital Bichat, Paris, France) ; Pasquet, B. (Hôpital Bichat, Paris, France) ; Dubief, E. (Hôpital Louis Mourier, Colombes, France) ; Dreyfuss, D. (Hôpital Louis Mourier, Colombes, France) ; Tubach, F. (Hôpital Bichat, Paris, France) ; Battle, C. (Morriston Hospital, Swansea, UK) ; James, K. (Morriston Hospital, Swansea, UK) ; Temblett, P. (Morriston Hospital, Swansea, UK) ; Davies, L. (Abertawe Bro Morgannwg University Health Board, Swansea, UK) ; Battle, C. (Abertawe Bro Morgannwg University Health Board, Swansea, UK) ; Lynch, C. (Abertawe Bro Morgannwg University Health Board, Swansea, UK) ; Pereira, S. (Centro Hospitalar Porto, Porto, Portugal) ; Cavaco, S. (Centro Hospitalar Porto, Porto, Portugal) ; Fernandes, J. (Centro Hospitalar Porto, Porto, Portugal) ; Moreira, I. (Centro Hospitalar Porto, Porto, Portugal) ; Almeida, E. (Centro Hospitalar Porto, Porto, Portugal) ; Seabra Pereira, F. (Centro Hospitalar Porto, Porto, Portugal) ; Malheiro, M. (Centro Hospitalar Porto, Porto, Portugal) ; Cardoso, F. (Centro Hospitalar Porto, Porto, Portugal) ; Aragão, I. (Centro Hospitalar Porto, Porto, Portugal) ; Cardoso, Teresa (Centro Hospitalar Porto, Porto, Portugal) ; Fister, M. (Rihard Knafelj, Ljubljana, Slovenia) ; Knafelj, R. (Rihard Knafelj, Ljubljana, Slovenia) ; Muraray Govind, P. (Apollo Speciality Hospital - OMR, Chennai, India) ; Brahmananda Reddy, N. (Apollo Speciality Hospital - OMR, Chennai, India) ; Pratheema, R. (Apollo Speciality Hospital - OMR, Chennai, India) ; Arul, E. D. (Apollo Speciality Hospital - OMR, Chennai, India) ; Devachandran, J. (Apollo Speciality Hospital - OMR, Chennai, India) ; Velasco, M. B. (Hospital Meridional S.A., Cariacica, Brazil) ; Dalcomune, D. M. (Hospital Meridional S.A., Cariacica, Brazil) ; Knafelj, R. (Rihard Knafelj, Ljubljana, Slovenia) ; Fister, M. (Rihard Knafelj, Ljubljana, Slovenia) ; Chin-Yee, N. (The Ottawa Hospital, Ottawa, Canada) ; D'Egidio, G. (The Ottawa Hospital, Ottawa, Canada) ; Thavorn, K. (The Ottawa Hospital, Ottawa, Canada) ; Heyland, D. (Kingston General Hospital, Kingston, Canada) ; Kyeremanteng, K. (The Ottawa Hospital, Ottawa, Canada) ; Murchison, A. G. (Milton Keynes Hospital, Milton Keynes, UK) ; Swalwell, K. (Imperial College, London, UK) ; Mandeville, J. (Buckinghamshire Healthcare NHS Trust, Aylesbury, UK) ; Stott, D. (Buckinghamshire Healthcare NHS Trust, Aylesbury, UK) ; Guerreiro, I. (IPO -Porto, Porto, Portugal) ; Devine, H. (Glasgow Royal Infirmary, Glasgow, UK) ; MacTavish, P. (Glasgow Royal Infirmary, Glasgow, UK) ; McPeake, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Quasim, T. (Glasgow Royal Infirmary, Glasgow, UK) ; Kinsella, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Daniel, M. (Glasgow Royal Infirmary, Glasgow, UK) ; Goossens, C. (KU Leuven, Leuven, Belgium) ; Marques, M. B. ; Derde, S. (KU Leuven, Leuven, Belgium) ; Vander Perre, S. (KU Leuven, Leuven, Belgium) ; Dufour, T. (KU Leuven, Leuven, Belgium) ; Thiessen, S. E. (KU Leuven, Leuven, Belgium) ; Güiza, F. (KU Leuven, Leuven, Belgium) ; Janssens, T. (KU Leuven, Leuven, Belgium) ; Hermans, G. (KU Leuven, Leuven, Belgium) ; Vanhorebeek, I. (KU Leuven, Leuven, Belgium) ; De Bock, K. (KU Leuven, Leuven, Belgium) ; Van den Berghe, G. (KU Leuven, Leuven, Belgium) ; Langouche, L. (KU Leuven, Leuven, Belgium) ; Devine, H. (Glasgow Royal Infirmary, Glasgow, UK) ; MacTavish, P. (Glasgow Royal Infirmary, Glasgow, UK) ; Quasim, T. (Glasgow Royal Infirmary, Glasgow, UK) ; Kinsella, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Daniel, M. (Glasgow Royal Infirmary, Glasgow, UK) ; McPeake, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Miles, B. (Glasgow Royal Infirmary, Glasgow, UK) ; Madden, S. (Glasgow Royal Infirmary, Glasgow, UK) ; Devine, H. (Glasgow Royal Infirmary, Glasgow, UK) ; Weiler, M. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Marques, P. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Rodrigues, C. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Boeira, M. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Brenner, K. ; Leães, C. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Machado, A. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Townsend, R. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; Andrade, J. (Ernesto Dornelles Hospital, Porto Alegre, Brazil) ; MacTavish, P. (Glasgow Royal Infirmary, Glasgow, UK) ; McPeake, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Devine, H. (Glasgow Royal Infirmary, Glasgow, UK) ; Kinsella, J. (Glasgow Royal Infirmary, Glasgow, UK) ; Daniel, M. (Glasgow Royal Infirmary, Glasgow, UK) ; Kishore, R. (Glasgow Royal Infirmary, Glasgow, UK) ; Fenlon, C. (Glasgow Royal Infirmary, Glasgow, UK) ; Quasim, T. (Glasgow Royal Infirmary, Glasgow, UK) ; Fiks, T. (Gelre Ziekenhuizen, Apeldoorn, Netherlands) ; Ruijter, A. (Gelre Ziekenhuizen, Apeldoorn, Netherlands) ; Te Raa, M. (Gelre Ziekenhuizen, Apeldoorn, Netherlands) ; Spronk, P. (Gelre Ziekenhuizen, Apeldoorn, Netherlands) ; Chiew, Y. S. (University of Canterbury, Christchurch, New Zealand) ; Docherty, P. (University of Canterbury, Christchurch, New Zealand) ; Dickson, J. (University of Canterbury, Christchurch, New Zealand) ; Moltchanova, E. (University of Canterbury, Christchurch, New Zealand) ; Scarrot, C. (University of Canterbury, Christchurch, New Zealand) ; Pretty, C. (University of Canterbury, Christchurch, New Zealand) ; Shaw, G. M. (Christchurch Hospital, Christchurch, New Zealand) ; Chase, J. G. (University of Western Ontario, London, Canada) ; Hall, T. (Surrey and Sussex NHS Trust, Redhill, UK) ; Ngu, W. C. (Surrey and Sussex NHS Trust, Redhill, UK) ; Jack, J. M. (Surrey and Sussex NHS Trust, Redhill, UK) ; Morgan, P. (Surrey and Sussex NHS Trust, Redhill, UK) ; Avard, B. (The Canberra Hospital, Hughes, ACT Australia) ; Pavli, A. (The Canberra Hospital, Hughes, ACT Australia) ; Gee, X. (ANU Medical School, Canberra, Australia) ; Bor, C. (Ege University School of Medicine, Izmir, Turkey) ; Akin Korhan, E. (katip Celebi University, Izmir, Turkey) ; Demirag, K. (Ege University School of Medicine, Izmir, Turkey) ; Uyar, M. (Ege University School of Medicine, Izmir, Turkey) ; Shirazy, M. (Alexandria University Faculty of medicine, Alexandria, Egypt) ; Fayed, A. (Alexandria University Faculty of medicine, Alexandria, Egypt) ; Gupta, S. (Fortis Escorts Heart Institute, New Delhi, India) ; Kaushal, A. (Fortis Escorts Heart Institute, New Delhi, India) ; Dewan, S. (FMRI, Gurgaon, India) ; Varma, A. (Fortis Escorts Heart Institute, New Delhi, India) ; Ghosh, E. (Philips Research North America, Cambridge, USA) ; Yang, L. (Philips Research North America, Cambridge, USA) ; Eshelman, L. (Philips Research North America, Cambridge, USA) ; Lord, B. (Philips Research North America, Cambridge, USA) ; Carlson, E. (Philips Research North America, Cambridge, USA) ; Helme, E. (King's College Hospital NHS Foundation Trust) ; Broderick, R. (King's College Hospital NHS Foundation Trust) ; Hadfield, S. (King's College Hospital NHS Foundation Trust) ; Loveridge, R. (King's College Hospital NHS Foundation Trust) ; Ramos, J. (Hospital Sao Rafael, Salvador, Brazil) ; Forte, D. (Hospital das Clinicas, Sao Paulo, Brazil) ; Yang, F. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Hou, P. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Dudziak, J. (St Helens and Knowsley, Liverpool, UK) ; Feeney, J. (St Helens and Knowsley, Liverpool, UK) ; Wilkinson, K. (St Helens and Knowsley, Liverpool, UK) ; Bauchmuller, K. (STH, Sheffield, UK) ; Shuker, K. (STH, Sheffield, UK) ; Faulds, M. (STH, Sheffield, UK) ; Raithatha, A. (STH, Sheffield, UK) ; Bryden, D. (STH, Sheffield, UK) ; England, L. (St Helens and Knowsley, Liverpool, UK) ; Bolton, N. (St Helens and Knowsley, Liverpool, UK) ; Tridente, A. (St Helens and Knowsley, Liverpool, UK) ; Bauchmuller, K. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Shuker, K. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Tridente, A. (Whiston Hospital, Prescot, UK) ; Faulds, M. (Freeman Hospital, Newcastle upon Tyne, UK) ; Matheson, A. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Gaynor, J. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Bryden, D. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Ramos, J. (Hospital Sao Rafael, Salvador, Brazil) ; Peroni, B. (Hospital das Clinicas, Sao Paulo, Brazil) ; Daglius-Dias, R. (Hospital das Clinicas, Sao Paulo, Brazil) ; Miranda, L. (Hospital Nove de Julho, Sao Paulo, Brazil) ; Cohen, C. (Hospital das Clinicas, Sao Paulo, Brazil) ; Carvalho, C. (Hospital das Clinicas, Sao Paulo, Brazil) ; Velasco, I. (Hospital das Clinicas, Sao Paulo, Brazil) ; Forte, D. (Hospital das Clinicas, Sao Paulo, Brazil) ; Kelly, J. M. (University Hospital Coventry and Warwickshire, Coventry, UK) ; Neill, A. (Sunnybrook Health Sciences Centre, Toronto, Canada) ; Rubenfeld, G. (Sunnybrook Health Sciences Centre, Toronto, Canada) ; Masson, N. (NHS Scotland, Glasgow, UK) ; Min, A. (Royal College of Surgeons of Ireland, Dublin, Ireland) ; Boezeman, E. (University Leiden, Leiden, Netherlands) ; Hofhuis, J. (Gelre Hospitals, Apeldoorn, Netherlands) ; Hovingh, A. (Gelre Hospitals, Apeldoorn, Netherlands) ; De Vries, R. (VU University Amsterdam, Amsterdam, Netherlands) ; Spronk, P. (Gelre Hospitals, Apeldoorn, Netherlands) ; Cabral-Campello, G. (Hospital de Santo António, Oporto Hospital Center, Porto, Portugal) ; Aragão, I. (Hospital de Santo António, Oporto Hospital Center, Porto, Portugal) ; Cardoso, Teresa (Hospital de Santo António, Oporto Hospital Center, Porto, Portugal) ; Van Mol, M. (Erasmus MC, Rotterdam, Netherlands) ; Nijkamp, M. (Faculty of Psychology and Educational Sciences, Heerlen, Netherlands) ; Kompanje, E. (Erasmus MC, Rotterdam, Netherlands) ; Ostrowski, P. (University of Toronto at Scarborough, Scarborough, ON Canada) ; Omar, A. (Hamad medical corporation, Doha, Qatar) ; Kiss, K. (University of Szeged, Szeged, Hungary) ; Köves, B. (Jahn Ferenc Hospital, Budapest, Hungary) ; Csernus, V. (University of Pécs, Pécs, Hungary) ; Molnár, Zsolt (University of Szeged, Szeged, Hungary) ; Hoydonckx, Y. (Jessa Ziekenhuis, Hasselt, Belgium) ; Vanwing, S. (Jessa Ziekenhuis, Hasselt, Belgium) ; Stessel, B. (Jessa Ziekenhuis, Hasselt, Belgium) ; Van Assche, A. (Jessa Ziekenhuis, Hasselt, Belgium) ; Jamaer, L. (Jessa Ziekenhuis, Hasselt, Belgium) ; Dubois, J. (Jessa Ziekenhuis, Hasselt, Belgium) ; Medo, V. (Hospital Clinico Universidad de Chile (Santiago de Xile, Xile)) ; Galvez, R. (Hospital Clinico Universidad de Chile (Santiago de Xile, Xile)) ; Miranda, J. P. (Hospital Clinico Universidad de Chile (Santiago de Xile, Xile)) ; Stone, C. (Royal Marsden Hospital (Regne Unit)) ; Wigmore, T. (Royal Marsden Hospital (Regne Unit)) ; Arunan, Y. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Wheeler, A. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Bauchmuller, K. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Bryden, D. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Wong, Y. (Tan Tock Seng hospital, Singapore, Singapore) ; Poi, C. ; Gu, C. (Tan Tock Seng hospital, Singapore, Singapore) ; Molmy, P. (Centre Hospitalier de Lens, Lens, France) ; Van Grunderbeeck, N. (Centre Hospitalier de Lens, Lens, France) ; Nigeon, O. (Centre Hospitalier de Lens, Lens, France) ; Lemyze, M. (Centre Hospitalier de Lens, Lens, France) ; Thevenin, D. (Centre Hospitalier de Lens, Lens, France) ; Mallat, J. (Centre Hospitalier de Lens, Lens, France) ; Ramos, J. (Hospital Sao Rafael, Salvador, Brazil) ; Correa, M. (Hospital das Clinicas, Sao Paulo, Brazil) ; Carvalho, R. T. (Hospital das Clinicas, Sao Paulo, Brazil) ; Forte, D. (Hospital das Clinicas, Sao Paulo, Brazil) ; Fernandez, A. (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ; McBride, C. (University of Texas at Austin, San Antonio, USA) ; Koonthalloor, E. (Beaumont Hospital (Dublín, Irlanda)) ; Walsh, C. (Beaumont Hospital (Dublín, Irlanda)) ; Webber, A. (St Helens and Knowsley teaching hospitals, Liverpool, UK) ; Ashe, M. (St Helens and Knowsley teaching hospitals, Liverpool, UK) ; Smith, K. (St Helens and Knowsley teaching hospitals, Liverpool, UK) ; Jeanrenaud, P. (St Helens and Knowsley teaching hospitals, Liverpool, UK) ; Marudi, A. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Baroni, S. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Ragusa, F. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Bertellini, E. (Nuovo Ospedale Civile Sant'Agostino Estense, Modena, Italy) ; Volakli, E. A. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Chochliourou, E. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Dimitriadou, M. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Violaki, A. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Mantzafleri, P. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Samkinidou, E. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Vrani, O. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Arbouti, A. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Varsami, T. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Sdougka, M. (PICU, Hippokration General Hospital, Thessaloniki, Greece) ; Bollen, J. A. (Maastricht University, Maastricht, Netherlands) ; Van Smaalen, T. C. (Maastricht University Medical Center, Maastricht, Netherlands) ; De Jongh, W. C. (Maastricht University Medical Center, Maastricht, Netherlands) ; Ten Hoopen, M. M. (Maastricht University, Maastricht, Netherlands) ; Ysebaert, D. (University Hospital Antwerp (Bèlgica)) ; Van Heurn, L. W. (Academic Medical Center, Amsterdam, Netherlands) ; Van Mook, W. N. (Maastricht University Medical Center, Maastricht, Netherlands) ; Sim, K. (St Helens and Knoowsley, Prescot, UK) ; Fuller, A. (St Helens and Knoowsley, Prescot, UK) ; Roze des Ordons, A. (University of Calgary, Calgary, Canada) ; Couillard, P. (University of Calgary, Calgary, Canada) ; Doig, Christopher (University of Calgary, Calgary, Canada) ; Van Keer, R. V. (Vrije Universiteit Brussel, Brussel, Belgium) ; Deschepper, R. D. (Vrije Universiteit Brussel, Brussel, Belgium) ; Francke, A. F. (EMGO+/VU University medical center, Utrecht, Netherlands) ; Huyghens, Luc H. (Universitair Ziekenhuis Brussel, Brussel, Belgium) ; Bilsen, Johan B. (Vrije Universiteit Brussel, Brussel, Belgium) ; Nyamaizi, B. (University Hospital Lewisham, London, UK) ; Dalrymple, C. (Queen Elizabeth Hospital, London, UK) ; Molokhia, A. (University Hospital Lewisham, London, UK) ; Dobru, A. (University Hospital Lewisham, London, UK) ; Marrinan, E. (Lewisham & Greenwich NHS Trust, London, UK) ; Ankuli, A. (Lewisham & Greenwich NHS Trust, London, UK) ; Molokhia, A. (Lewisham & Greenwich NHS Trust, London, UK) ; McPeake, J. (University of Glasgow, Glasgow, UK) ; Struthers, R. (NHS Greater Glasgow and Clyde, Glasgow, UK) ; Crawford, R. (NHS Greater Glasgow and Clyde, Glasgow, UK) ; Devine, H. (NHS Greater Glasgow and Clyde, Glasgow, UK) ; Mactavish, P. (NHS Greater Glasgow and Clyde, Glasgow, UK) ; Quasim, T. (University of Glasgow, Glasgow, UK) ; Morelli, P. (National Burn Unit, Montevideo, Uruguay) ; Degiovanangelo, M. (National Burn Unit, Montevideo, Uruguay) ; Lemos, F. (National Burn Unit, Montevideo, Uruguay) ; MArtinez, V. (Hospital Maciel, Montevideo, Uruguay) ; Verga, F. (National Burn Unit, Montevideo, Uruguay) ; Cabrera, J. (National Burn Unit, Montevideo, Uruguay) ; Burghi, Gastón (Hospital Maciel, Montevideo, Uruguay) ; Rutten, A. (St Elisabeth Ziekenhuis, Tilburg, Netherlands) ; Van Ieperen, S. (St Elisabeth Ziekenhuis, Tilburg, Netherlands) ; De Geer, S. (St Elisabeth Ziekenhuis, Tilburg, Netherlands) ; Van Vugt, M. (St Elisabeth Ziekenhuis, Tilburg, Netherlands) ; Der Kinderen, Ethel (St Elisabeth Ziekenhuis, Tilburg, Netherlands) ; Giannini, A. (Fondazione IRCCS Ca' Granda - Ospedale maggiore Policlinico, Milan, Italy) ; Miccinesi, Guido (Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy) ; Marchesi, Tiziana (Fondazione IRCCS Ca' Granda - Ospedale maggiore Policlinico, Milan, Italy) ; Prandi, Edi (Fondazione IRCCS Ca' Granda - Ospedale maggiore Policlinico, Milan, Italy)
2016 - 10.1186/s13054-016-1358-6
Critical Care, Vol. 20 (october 2016)  
5.
15 p, 3.0 MB Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia / Zielen, Stefan (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Duecker, Ruth Pia (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Woelke, Sandra (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Donath, Helena (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Bakhtiar, Shahrzad (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Buecker, Aileen (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Kreyenberg, Hermann (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Huenecke, Sabine (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Bader, Peter (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Mahlaoui, Nizar (Necker Children's University Hospital. Pediatric Immunology-Hematology and Rheumatology Unit) ; Ehl, Stephan (University of Freiburg. Institute for Immunodeficiency) ; El-Helou, Sabine M. (Hannover Medical School. Department of Rheumatology and Immunology) ; Pietrucha, Barbara (The Children's Memorial Health Institute. Department of Immunology) ; Plebani, Alessandro (University of Brescia. Department of Clinical and Experimental Sciences) ; van der Flier, Michiel (Radboud University Medical Center. Section Pediatric Infectious Diseases) ; van Aerde, Koen (Radboud University Medical Center. Department of Pediatrics) ; Kilic, Sara S. (Uludag University. Department of Pediatric Immunology and Rheumatology) ; Reda, Shereen M. (Ain Shams University. Department of Pediatrics) ; Kostyuchenko, Larysa (Western Ukrainian Specialized Children's Medical Centre) ; McDermott, Elizabeth (Nottingham University Hospitals NHS Trust (Regne Unit)) ; Galal, Nermeen (Cairo University Specialized Pediatric Hospital. Department of Pediatrics) ; Pignata, Claudio (Federico II University. Department of Translational Medical Sciences) ; Santos-Pérez, Juan Luis (Hospital Universitario Virgen de las Nieves (Granada)) ; Laws, Hans-Juergen (Heinrich-Heine University. Department of Pediatric Oncology, Hematology and Clinical Immunology) ; Niehues, Tim (Centre for Child and Adolescent Health (Krefeld, Germany)) ; Kutukculer, Necil (Ege University. Department of Pediatric Immunology) ; Seidel, Markus G. (Medical University Graz. Department of Pediatrics and Adolescent Medicine) ; Marques, Laura (Porto Hospital Center. Pediatric Department) ; Ciznar, Peter (Comenius University in Bratislava. Pediatric Department) ; Edgar, John David M. (The Royal Hospitals & Queen's University) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; von Bernuth, Horst (Charité - Universitätsmedizin Berlin) ; Krueger, Renate (Charité - Universitätsmedizin Berlin) ; Meyts, Isabelle (University Hospitals Leuven (Bèlgica)) ; Baumann, Ulrich (Hannover Medical School. Department of Paediatric Pulmonology, Allergy and Neonatology) ; Kanariou, Maria ("Aghia Sophia" Children's Hospital. Department of Immunology and Histocompatibility) ; Grimbacher, Bodo (Albert-Ludwigs University) ; Hauck, Fabian (Ludwig-Maximilians-University Munich. Department of Pediatrics) ; Graf, Dagmar (MVZ Dr. Reising-Ackermann Und Kollegen (Leipzig, Germany)) ; Granado, Luis Ignacio Gonzalez (Universidad Complutense de Madrid) ; Prader, Seraina (University Children's Hospital Zurich. Division of Immunology and Children's Research Center) ; Reisli, Ismail (Necmettin Erbakan University. Department of Pediatrics) ; Slatter, Mary (Newcastle University. Primary Immunodeficiency Group, Paediatric Immunology and Haematopoietic Stem Cell Transplantation) ; Rodríguez-Gallego, Carlos (University Fernando Pessoa Canarias. Department of Immunology) ; Arkwright, Peter D. (University of Manchester. Lydia Becker Institute of Immunology and Inflammation) ; Bethune, Claire (University Hospitals Plymouth NHS Trust (Regne Unit)) ; Deripapa, Elena (National Medical Research Center of Pediatric Hematology, Oncology and Immunology (Moscow, Russia)) ; Sharapova, Svetlana O. (Belarusian Research Center for Pediatric Oncology, Hematology and Immunology. Research Department) ; Lehmberg, Kai (University Medical Center Hamburg-Eppendorf. Division for Pediatric Stem Cell Transplantation and Immunology) ; Davies, E. Graham (Great Ormond Street Hospital for Children (Londres)) ; Schuetz, Catharina (Technische Universität Dresden. Department of Pediatrics) ; Kindle, Gerhard (University of Freiburg. FREEZE Biobank) ; Schubert, Ralf (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Universitat Autònoma de Barcelona
Patients with ataxia-telangiectasia (A-T) sufer from progressive cerebellar ataxia, immunodefciency, respiratory failure, and cancer susceptibility. From a clinical point of view, A-T patients with IgA defciency show more symptoms and may have a poorer prognosis. [...]
2021 - 10.1007/s10875-021-01090-8
Journal of Clinical Immunology, Vol. 41 (september 2021) , p. 1878-1892  
6.
18 p, 1.3 MB Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 / Zhang, Qian (St. Rockefeller University) ; Liu, Zhiyong (Rockefeller University) ; Moncada-Velez, Marcela (Rockefeller University) ; Chen, Jie (Rockefeller University) ; Ogishi, Masato (Rockefeller University) ; Bigio, Benedetta (Rockefeller University) ; Yang, Rui (Rockefeller University) ; Arias, Andrés Augusto (Universidad de Antioquia) ; Zhou, Qinhua (Rockefeller University) ; Han, Ji Eun (Rockefeller University) ; Ugurbil, Aileen Camille (Rockefeller University) ; Zhang, Peng (Rockefeller University) ; Rapaport, Franck (Rockefeller University) ; Li, Juan (Rockefeller University) ; Spaan, András N. (University Medical Center Utrecht) ; Boisson, Bertrand (University of Paris) ; Boisson-Dupuis, S. (University of Paris) ; Bustamante, J. (Necker Hospital for Sick Children) ; Puel, A. (University of Paris) ; Ciancanelli, Michael J (Turnstone Biologics) ; Zhang, Shen-Ying (University of Paris) ; Béziat, V. (University of Paris) ; Jouanguy, E. (University of Paris) ; Abel, Laurent (INSERM U1163. University of Paris) ; Cobat, A. (University of Paris) ; Casanova, Jean-Laurent (Rockefeller University) ; Bastard, Paul (University of Paris) ; Korol, Cecilia (Necker Hospital for Sick Children, Paris) ; Rosain, Jérémie (University of Paris) ; Philippot, Q. (APHP Tenon Hospital) ; Chbihi, Marwa (University of Paris. Imagine Institute) ; Lorenzo, L. (University of Paris. Imagine Institute) ; Bizien, L. (University of Paris. Imagine Institute) ; Neehus, A. L. (University of Paris. Imagine Institute) ; Kerner, G. (University of Paris. Imagine Institute) ; Seeleuthner, Y. (University of Paris. Imagine Institute) ; Manry, J. (University of Paris. Imagine Institute) ; Le Voyer, T. (University of Paris. Imagine Institute) ; Boisson, Bertrand (University of Paris. Imagine Institute) ; Boisson-Dupuis, S. (University of Paris. Imagine Institute) ; Bustamante, J. (Necker Hospital for Sick Children. AP-HP) ; Puel, A. (University of Paris. Imagine Institute) ; Zhang, S. Y. (University of Paris. Imagine Institute) ; Béziat, V. (University of Paris. Imagine Institute) ; Jouanguy, E. (University of Paris) ; Abel, Laurent (University of Paris) ; Cobat, A. (University of Paris) ; Bastard, Paul (University of Paris) ; Rosain, J. (University of Paris) ; Philippot, Q. (APHP Tenon Hospital) ; Chbihi, M. (University of Paris) ; Lorenzo, L. (University of Paris) ; Bizien, L. (University of Paris) ; Neehus, A. L. (University of Paris) ; Kerner, G. (University of Paris) ; Seeleuthner, Y. (University of Paris) ; Manry, J. (University of Paris) ; Le Voyer, T. (University of Paris) ; Boisson, Bertrand (University of Paris) ; Boisson-Dupuis, S. (University of Paris) ; Bustamante, J. (Necker Hospital for Sick Children) ; Puel, A. (University of Paris) ; Zhang, S. Y. (University of Paris) ; Béziat, Vivien (University of Paris) ; Jouanguy, Emmanuelle (University of Paris) ; Abel, Laurent (INSERM U1163. University of Paris) ; Cobat, Aurélie (University of Paris) ; Le Pen, Jérémie (Rockefeller University) ; Schneider, W. M. (Rockefeller University) ; Razooky, B. S. (Rockefeller University) ; Hoffmann, H. H. (Rockefeller University) ; Michailidis, E. (Rockefeller University) ; Rice, Charles M. (Rockefeller University) ; Sabli, Ira K. D. (Imperial College London) ; Hodeib, Stephanie (Imperial College London) ; Sancho Shimizu, Vanessa (Imperial College London) ; Bilguvar, Kaya (Yale School of Medicine) ; Ye, Junqiang (Columbia University) ; Bolze, Alexandre (Helix) ; Zhang, Y. (NIAID Clinical Genomics Program) ; Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Su, H. C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Zhang, Y. (NIAID Clinical Genomics Program) ; Notarangelo, L. D. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Su, H. C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Onodi, Fanny (Université de Paris) ; Korniotis, Sarantis (Université de Paris) ; Karpf, Léa (Université de Paris. Institut de Recherche Saint-Louis. INSERM U976. Hôpital Saint-Louis) ; Soumelis, V. (AP-HP. Hôpital Saint-Louis. Laboratoire d'Immunologie) ; Bonnet-Madin, Lucie (Université de Paris. Institut de Recherche Saint-Louis) ; Amara, A. (Université de Paris. Institut de Recherche Saint-Louis) ; Dorgham, Karim (Sorbonne Université. Inserm. Centre d'Immunologie et des Maladies Infectieuses-Paris (CIMI PARIS). Assistance Publique-Hôpitaux de Paris (AP-HP). Hôpital Pitié-Salpêtrière) ; Gorochov, Guy (Sorbonne Université) ; Smith, N. (Institut Pasteur) ; Duffy, Darragh (Institut Pasteur) ; Moens, L. (University Hospitals Leuven (Bèlgica)) ; Meyts, I. (KU Leuven. Department of Immunology. Microbiology and Transplantation) ; Meade, P. (Department of Microbiology) ; Garcia-Sastre, Adolfo (Tisch Cancer Institute) ; Krammer, Florian (Department of Microbiology) ; Corneau, A. (Sorbonne Université) ; Masson, C. (Imagine Institute) ; Schmitt, Y. (Imagine Institute) ; Schluter, A. (Neurometabolic Diseases Laboratory) ; Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ; Khan, T. (Sidra Medicine) ; Marr, Nico (Hamad Bin Khalifa University) ; Fellay, Jacques (Swiss Federal Institute of Technology Lausanne) ; Roussel, L. (McGill University Health Centre) ; Vinh, D. C. (McGill University Health Centre) ; Shahrooei, M. (Saeed Pathobiology and Genetic Lab) ; Alosaimi, M. F. (College of Medicine. King Saud University) ; Alsohime, F. ; Hasanato, R. (Department of Pathology and Laboratory Medicine. College of Medicine. King Saud University) ; Mansouri, D. (Shahid Beheshti University of Medical Sciences) ; Al-Saud, H. (National Center of Genomics Technology. King Abdulaziz City for Science and Technology) ; Almourfi, F. (National Center of Genomics Technology. King Abdulaziz City for Science and Technology) ; Al-Mulla, F. (Kuwait University) ; Al-Muhsen, S. Z. (Immunology Research Laboratory. Department of Pediatrics. College of Medicine. King Saud University Medical City. King Saud University) ; Al Turki, S. (Cancer & Blood Research. King Abdullah International Medical Research Center) ; van de Beek, D. (Amsterdam UMC. University Medical Center) ; Biondi, A. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ; Bettini, L. R. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ; D'Angio, M. (Pediatric Departement. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale) ; Bonfanti, Paolo (Department of Infectious Diseases. San Gerardo Hospital. University of Milano-Bicocca) ; Imberti, L. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ; Sottini, A. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ; Paghera, S. (CREA Laboratory. Diagnostic Laboratory. ASST Spedali Civili di Brescia) ; Quiros-Roldan, E. (Department of Infectious and Tropical Diseases. University of Brescia. ASST Spedali di Brescia) ; Rossi, C. (Medical Officer. ASST Spedali Civili di Brescia) ; Oler, A. J. (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ; Tompkins, M. F. (PRIMER. Uniformed Services University of the Health Sciences) ; Alba, Camille (PRIMER. Uniformed Services University of the Health Sciences) ; Dalgard, C. L. (American Genome Center. Uniformed Services University of the Health Sciences) ; Vandernoot, Isabelle (Center of Human Genetics. Hôpital Erasme. Université Libre de Bruxelles) ; Smits, Guillaume (Center of Human Genetics. Hôpital Erasme. Université Libre de Bruxelles) ; Goffard, Jean-Christope (Department of Internal Medicine. Hôpital Erasme. Université Libre de Bruxelles) ; Migeotte, Isabelle (Hôpital Erasme) ; Haerynck, Filomeen (Department of Paediatric Immunology and Pulmonology. Centre for Primary Immunodeficiency Ghent (CPIG). PID Research Lab. Jeffrey Modell Diagnosis and Research Centre. Ghent University Hospital) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ; Martín-Nalda, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ; Morange, Pierre-Emmanuel (Aix Marseille Univ) ; Keles, Sevgi (Meram Medical Faculty. Necmettin Erbakan University. Meram Medical Faculty) ; Çölkesen, Fatma (Department of Infectious Diseases and Clinical Microbiology. Konya Training and Research Hospital) ; Ozcelik, Tayfun (Bilkent University) ; Yasar, Tayfun Kart (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ; Senoglu, Sevtap (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ; Karabela, Şemsi Nur (Departments of Infectious Diseases and Clinical Microbiology. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. University of Health Sciences) ; Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ; Novelli, Giuseppe (University of Rome "Tor Vergata) ; Hraiech, Sami (Intensive Care Unit) ; Tandjaoui-Lambiotte, Yacine (Avicenne Hospital) ; Duval, Xavier (Hôpital Bichat Claude Bernard) ; Laouénan, Cédric (Hôpital Bichat) ; Duval, X. (Hôpital Bichat Claude Bernard) ; Snow, Andrew (Uniformed Services University of the Health Sciences, Bethesda) ; Dalgard, Clifton L. (American Genome Center) ; Milner, Joshua D. (Columbia University) ; Mogensen, Trine Hyrup (Aarhus University) ; Spaan, András N. (Univer-sity Medical Center Utrecht) ; Bustamante, Jacinta (Necker Hospital for Sick Children) ; Ciancanelli, Michael J. (Turnstone Biologics) ; Maniatis, Tom (New York Genome Center) ; Soumelis, Vassili (Hôpital Saint-Louis, Paris) ; Nussenzweig, Michel (Howard Hughes Medical Institute) ; Garcia-Sastre, Adolfo (Icahn School of Medicine) ; Lifton, Richard P. (Yale School of Medicine) ; Foti, Giuseppe (University of Milano-Bicocca) ; Bellani, G. (University of Milano-Bicocca) ; Citerio, Giuseppe (University of Milano-Bicocca) ; Contro, E. (University of Milano-Bicocca) ; Pesci, Alberto (University of Milano-Bicocca.) ; Valsecchi, M. G. (University of Milano-Bicocca) ; Cazzaniga, M. (University of Milano-Bicocca) ; Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodrigo, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Aguilera-Albesa, Sergio (Complejo Hospitalario de Navarra) ; Akcan, O. M. (Necmettin Erbakan University) ; Darazam, I. A. (Shahid Beheshti University of Medical Sciences) ; Aldave, J. C. (Hospital Nacional Edgardo Rebagliati Martins) ; Ramos, M. A. (Parc Sanitari Sant Joan de Déu) ; Nadji, S. A. (Shahid Beheshti University of Medical Sciences) ; Alkan, G. (Selcuk University) ; Allardet-Servent, J. (Hôpital Européen) ; Allende-Martinez, Luis M (Hospital Universitario 12 de Octubre (Madrid)) ; Alsina, L. (Hospital Sant Joan de Déu (Manresa)) ; Alyanakian, M. A. (Necker Hospital for Sick Children) ; Amador-Borrero, B. (Université de Paris) ; Mouly, S. (Internal Medicine Department. Hôpital Lariboisière. APHP. Université de Paris) ; Sene, D. (Internal Medicine Department. Hôpital Lariboisière. APHP. Université de Paris) ; Amoura, Zahir (Internal Medicine Department. Pitié-Salpétrière Hospital) ; Mathian, Alexis (Internal Medicine Department. Pitié-Salpétrière Hospital) ; Antolí, Arnau (Hospital Universitari de Bellvitge) ; Blanch, G. R. (Hospital Universitari de Bellvitge) ; Riera, J. S. (Hospital Universitari de Bellvitge) ; Moreno, X. S. (Hospital Universitari de Bellvitge) ; Arslan, S. (Necmettin Erbakan University) ; Assant, S. (Lyon Sud Hospital) ; Auguet, Teresa (Hospital Universitari Joan XXIII de Tarragona) ; Azot, A. (Private Practice) ; Bajolle, F. (Necker Hospital for Sick Children) ; Bustamante, J. (Necker Hospital for Sick Children) ; Lévy, R. (Necker Hospital for Sick Children) ; Oualha, M. (Necker Hospital for Sick Children) ; Baldolli, A. (Department of Infectious Diseases) ; Ballester Devis, Maria (Consorcio Hospital General Universitario) ; Feldman, H. B. (Tel Aviv University) ; Barrou, B. (Sorbonne Université.) ; Beurton, Alexandra (Hôpital Pitié-Salpêtrière) ; Bilbao, A. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ; Blanchard-Rohner, G. (Geneva University Hospitals (Suïssa)) ; Blandinières, A. (Georges Pompidou Hospital) ; Rivet, N. (Georges Pompidou Hospital) ; Blázquez-Gamero, Daniel (Hospital Universitario 12 de Octubre (Madrid)) ; Bloomfield, M. (Motol University Hospital) ; Bolivar-Prados, Mireia (Hospital de Mataró. Consorci Sanitari del Maresme) ; Clavé i Civit, Pere (rie, R.) ; Bosteels, C. (Universitair Ziekenhuis Gent) ; Lambrecht, B. N. (Universitair Ziekenhuis Gent) ; van Braeckel, E. (Universitair Ziekenhuis Gent) ; Bousfiha, Ahmed A (Averroes University Hospital D'Inflammation et d'Allergie. Hassann II University) ; Bouvattier, C. (Endocrinology Unit. APHP Hôpitaux Universitaires Paris-Sud) ; Vincent, A. (Endocrinology Unit. APHP Hôpitaux Universitaires Paris-Sud) ; Boyarchuk, O. (I. Horbachevsky Ternopil National Medical University) ; Bueno, M. R. P. (University of São Paulo) ; Castro, M. V. (University of São Paulo) ; Matos, L. R. B. (University of São Paulo) ; Zatz, M. (Human Genome and Stem-Cell Research Center. University of São Paulo) ; Agra, J. J. C. (Hospital Universitario Insular de Gran Canaria) ; Calimli, S. (Konya State Hospital) ; Capra, R. (Spedali Civili) ; Carrabba, M. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ; Fabio, G. (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ; Casasnovas, Carlos (Hospital Universitari de Bellvitge) ; Vélez-Santamaria, V. (Hospital Universitari de Bellvitge) ; Caseris, M. (Hopital Robert Debré) ; Falck, A. (Hopital Robert Debré) ; Poncelet, G. (Hopital Robert Debré) ; Castelle, M. (Necker Enfants Malades Hospital) ; Castelli, F. (University of Brescia) ; de Vera, M. C. (Canarian Health System) ; Catherinot, E. (Hôpital Foch) ; Chalumeau, M. (Necker Hospital for Sick Children) ; Toubiana, J. (Necker Hospital for Sick Children) ; Charbit, B. (Pasteur Institute) ; Li, Z. (Pasteur Institute) ; Pellegrini, S. (Pasteur Institute) ; Cheng, M. P. (McGill University Health Centre) ; Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Codina, A. (Institut de Recerca Sant Joan de Déu) ; Çölkesen, F. (Necmettin Erbakan University) ; Çölkesen, F. (Konya Training and Research Hospital) ; Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ; Comarmond, C. (Pitié-Salpêtrière Hospital) ; Dalmau, David (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Darley, D. R. (Vincent's Hospital Darlinghurst) ; Dauby, N. (Université Libre de Bruxelles) ; Dauger, S. (Robert-Debré University Hospital) ; Le Bourgeois, F. (Robert-Debré University Hospital) ; Levy, M. (Robert-Debré University Hospital) ; de Pontual, L. (Hôpital Jean Verdier) ; Dehban, A. (Sina Medical Complex) ; Delplancq, G. (Centre de Génétique Humaine) ; Demoule, A. (Sorbonne Université Médecine) ; Diehl, J. L. (Georges Pompidou Hospital) ; Dobbelaere, S. (AZ Delta) ; Durand, Sophie (Institut Jérôme Lejeune) ; Mircher, C. (Institut Jérôme Lejeune) ; Rebillat, A. S. (Institut Jérôme Lejeune) ; Vilaire, M. E. (Institut Jérôme Lejeune) ; Eldars, W. (DMansoura University) ; Elgamal, M. (Mansoura University) ; Elnagdy, M. H. (Mansoura University) ; Emiroglu, M. (Selcuk University) ; Erdeniz, E. H. (Ondokuz Mayıs University) ; Aytekin, S. E. (Necmettin Erbakan University) ; Euvrard, R. (Centre Hospitalier Fleyriat) ; Evcen, R. (Necmettin Erbakan University) ; Faivre, L. (CHU Dijon) ; Fartoukh, M. (APHP Tenon Hospital) ; Philippot, Q. (APHP Tenon Hospital) ; Faure, M. (Sorbonne Universités) ; Arquero, M. F. (Hospital Clínico San Carlos (Madrid)) ; Flores, Carlos (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ; Francois, B. (CHU Limoges) ; Fumadó, Victoria (Universitat de Barcelona) ; Fusco, Francesca (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso) ; Ursini, M. V. (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso) ; Solis, B. G. (Hospital Universitario La Paz (Madrid)) ; de Diego, R. P. (Hospital Universitario La Paz (Madrid)) ; van Den Rym, A. M. (Hospital Universitario La Paz (Madrid)) ; Gaussem, P. (Department of Hematology. APHP. Hopital Européen Georges Pompidou. Inserm UMR-S1140) ; Gil-Herrera, J. (Hos-pital General Universitario. Instituto de Investigación Sanitaria "Gregorio Marañón) ; Gilardin, L. (Bégin Military Hospital) ; Girona-Alarcón, Mònica (Hospital Sant Joan de Déu (Manresa)) ; Goffard, J. C. (Université Libre de Bruxelles) ; Gok, F. (Necmettin Erbakan University) ; Yosunkaya, A. (Necmettin Erbakan University) ; Thy, M. (Center for Clinical Investigation. Assistance Publique-Hôpitaux de Paris. Bichat-Claude Bernard University Hospital) ; van Agtmael, Michiel (Department of Infectious Diseases. Amsterdam UMC) ; Bomers, Marije (Department of Infectious Diseases. Amsterdam UMC) ; Chouchane, Osoul (Department of Infectious Diseases. Amsterdam UMC) ; Geerlings, Suzanne (Department of Infectious Diseases. Amsterdam UMC) ; Goorhuis, Bram (Department of Infectious Diseases. Amsterdam UMC) ; Grobusch, Martin P. (Department of Infectious Diseases. Amsterdam UMC) ; Harris, Vanessa (Department of Infectious Diseases. Amsterdam UMC) ; Hermans, Sabine M. (Department of Infectious Diseases. Amsterdam UMC) ; Hovius, Joppe W. (Department of Infectious Diseases. Amsterdam UMC) ; Nellen, Jeaninne (Department of Infectious Diseases. Amsterdam UMC) ; Peters, Edgar (Department of Infectious Diseases. Amsterdam UMC) ; van der Poll, Tom (Department of Infectious Diseases. Amsterdam UMC) ; Prins, Jan M. (Department of Infectious Diseases. Amsterdam UMC) ; Reijnders, Tom (Department of Infectious Diseases. Amsterdam UMC) ; Schinkel, Michiel (Department of Infectious Diseases. Amsterdam UMC) ; Sigaloff, Kim (Department of Infectious Diseases. Amsterdam UMC) ; Stijnis, Cornelis S. (Department of Infectious Diseases. Amsterdam UMC) ; van der Valk, Marc (Department of Infectious Diseases. Amsterdam UMC) ; van Vugt, Michèle (Department of Infectious Diseases. Amsterdam UMC) ; Joost Wiersinga, W. (Department of Infectious Diseases. Amsterdam UMC) ; Algera, Anna Geke (Department of Intensive Care. Amsterdam UMC) ; van Baarle, Frank (Department of Intensive Care. Amsterdam UMC) ; Bos, Lieuwe D.. (Department of Intensive Care. Amsterdam UMC) ; Botta, Michela (Department of Intensive Care. Amsterdam UMC) ; de Bruin, Sanne (Department of Intensive Care. Amsterdam UMC) ; Bulle, Esther (Department of Intensive Care. Amsterdam UMC) ; Elbers, Paul (Department of Intensive Care. Amsterdam UMC) ; Fleuren, Lucas (Department of Intensive Care. Amsterdam UMC) ; Girbes, Armand (Department of Intensive Care. Amsterdam UMC) ; Hagens, Laura (Department of Intensive Care. Amsterdam UMC) ; Heunks, Leo (Department of Intensive Care. Amsterdam UMC) ; Horn, Janneke (Department of Intensive Care. Amsterdam UMC) ; van Mourik, Niels (Department of Intensive Care. Amsterdam UMC) ; Paulus, Frederique (Department of Intensive Care. Amsterdam UMC) ; Raasveld, Jorinde (Department of Intensive Care. Amsterdam UMC) ; Schultz, Marcus J. (Department of Intensive Care. Amsterdam UMC) ; Smit, Marry (Department of Intensive Care. Amsterdam UMC) ; Stilma, Willemke (Department of Intensive Care. Amsterdam UMC) ; Thoral, Patrick (Department of Intensive Care. Amsterdam UMC) ; Tsonas, Anissa M (Department of Intensive Care. Amsterdam UMC) ; de Vries, Heder (Department of Intensive Care. Amsterdam UMC) ; Bax, Diane (Experimental Immunology. Amsterdam UMC) ; Cloherty, Alex (Experimental Immunology. Amsterdam UMC) ; Beudel, Martijn (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ; Brouwer, Matthijs C. (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ; Koning, Rutger (Department of Neurology. Amsterdam UMC. Amsterdam Neuroscience) ; van de Beek, Diederik (Amsterdam UMC. University Medical Center) ; Bogaard, H. J. (Department of Pulmonology. Amsterdam UMC) ; de Brabander, J. (Department of Infectious Diseases. Amsterdam UMC) ; de Bree, G. (Department of Infectious Diseases. Amsterdam UMC) ; Bugiani, Marianna (Department of Pathology. Amsterdam UMC) ; Geerts, Bart (Department of Anesthesiology. Amsterdam UMC) ; Hollmann, Markus W. (Department of Anesthesiology. Amsterdam UMC) ; Preckel, Benedikt (Department of Anesthesiology. Amsterdam UMC) ; Veelo, Denise (Department of Anesthesiology. Amsterdam UMC) ; Geijtenbeek, Theo (Department of Experimental Immunology. Amsterdam UMC) ; Hafkamp, Florianne (Department of Experimental Immunology. Amsterdam UMC) ; Hamann, Jorg (Amsterdam UMC Biobank Core Facility. Amsterdam UMC) ; Hemke, Robert (Department of Radiology. Amsterdam UMC) ; de Jong, Menno D. (Department of Medical Microbiology. Amsterdam UMC) ; Schuurman, Alex (Department of Internal Medicine. Amsterdam UMC) ; Teunissen, Charlotte (Neurochemical Laboratory. Amsterdam UMC) ; Vlaar, Alexander P. J. (Department of Intensive Care. Amsterdam UMC) ; Wouters, Dorien (Department of Clinical Chemistry. Amsterdam UMC) ; Zwinderman, A. H. (Department of Clinical Epidemiology. Biostatistics and Bioinformatics. Amsterdam UMC) ; Abel, Laurent (INSERM U1163. University of Paris. Imagine Institute) ; Aiuti, Alessandro (San Raffaele Telethon Institute for Gene Therapy. IRCCS Ospedale San Raffaele) ; Muhsen, Saleh Al (King Saud University) ; Al-Mulla, Fahd (Kuwait University) ; Anderson, Mark S. (University of California. San Francisco) ; Feldman, Hagit Baris (Genetics Institute. Tel Aviv Sourasky Medical Center. Sackler Faculty of Medicine. Tel Aviv University) ; Bogunovic, Dusan (Icahn School of Medicine) ; Itan, Yuval (Icahn School of Medicine) ; Bolze, Alexandre (Helix) ; Cirulli, Elizabeth (Helix) ; Barrett, Kelly Schiabor . (Helix) ; Washington, Nicole (Helix) ; Bondarenko, Anastasiia (Shupyk National Medical Academy for Postgraduate Education) ; Bousfiha, Ahmed A. (Clinical Immunology Unit. Pediatric Infectious Disease Departement. Faculty of Medicine and Pharmacy. Averroes University Hospital. LICIA Laboratoire d'Immunologie Clinique. D'Inflammation et d'Allergie. Hassann II University) ; Brodin, Petter (Karolinska Institutet (Estocolm, Suècia)) ; Bryceson, Yenan (Karolinska Institutet (Estocolm, Suècia)) ; Bustamante, Carlos D. (Stanford University) ; Butte, Manish J (University of California) ; Casari, Giorgio (Medical Genetics. IRCCS Ospedale San Raffaele) ; Chakravorty, Samya (Emory University. Department of Pediatrics. Children's Healthcare of Atlanta) ; Christodoulou, John (Murdoch Children's Research Institute) ; Le Mestre, S. (University of São Paulo) ; Condino-Neto, Antonio (University of São Paulo) ; Cooper, Megan A. (Washington University School of Medicine) ; Dalgard, Clifton L. (American Genome Center. Uniformed Services University of the Health Sciences) ; David, Alessia (Centre for Bioinformatics and System Biology. Department of Life Sciences. Imperial College London. South Kensington Campus) ; DeRisi, Joseph L. (Chan Zuckerberg Biohub) ; Desai, Murkesh (Bai Jerbai Wadia Hospital for Children) ; Drolet, Beth A. (School of Medicine and Public Health. University of Wisconsin) ; Espinosa, Sara (Instituto Nacional de Pediatria. (National Institute of Pediatrics)) ; Fellay, Jacques (Swiss Federal Institute of Technology Lausanne) ; Flores, Carlos (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ; Franco, Jose Luis (University of Antioquia) ; Gregersen, Peter K. (Feinstein Institute for Medical Research. Northwell Health USA) ; Haerynck, Filomeen (Department of Paediatric Immunology and Pulmonology. Centre for Primary Immunodeficiency Ghent (CPIG). PID Research Lab. Jeffrey Modell Diagnosis and Research Centre. Ghent University Hospital) ; Hagin, David (Genetics Institute. Tel Aviv Sourasky Medical Center) ; Halwani, Rabih (Sharjah Institute of Medical Research. College of Medicine. University of Sharjah) ; Heath, Jim (Institute for Systems Biology) ; Henrickson, Sarah E. (Children's Hospital of Philadelphia (Pennsilvània)) ; Hsieh, Elena (Anschutz Medical Campus) ; Imai, Kohsuke (Riken) ; Karamitros, Timokratis (Hellenic Pasteur Institute) ; Kisand, Kai (University of Tartu) ; Ku, Cheng-Lung. (Chang Gung University) ; Lau, Yu-Lung (University of Hong Kong) ; Ling, Yun (Shanghai Public Health Clinical Center. Fudan University) ; Lucas, Carrie L. (Yale School of Medicine) ; Mansouri, Davoud (Shahid Beheshti University of Medical Sciences) ; Marodi, Laszlo (Semmelweis University Budapest) ; Milner, Joshua (Columbia University Medical Center) ; Mironska, Kristina (University Clinic for Children's Diseases) ; Morio, Tomohiro (Tokyo Medical & Dental University Hospital) ; Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Su, Helen C. (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Novelli, Antonio (Bambino Gesù Children's Hospital) ; Novelli, Giuseppe (Department of Biomedicine and Prevention. University of Rome "Tor Vergata) ; O'Farrelly, Cliona (Trinity College) ; Okada, Satoshi (Hiroshima University) ; Ozcelik, Tayfun (Bilkent University) ; Perez de Diego, Rebeca (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ; Planas, Anna M. (IIBB-CSIC. IDIBAPS) ; Prando, Carolina (Faculdades Pequeno Príncipe. Instituto de Pesquisa Pelé Pequeno Príncipe) ; Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ; Quintana-Murci, Luis (Institut Pasteur. CNRS. UMR 2000. Collège de France) ; Renia, Laurent (Infectious Diseases Horizontal Technology Center. Singapore Immunology Network. Agency for Science Technology (A*STAR)) ; Renieri, Alessandra (Medical Genetics. University of Siena) ; Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ; Sancho Shimizu, Vanessa (Imperial College London) ; Sankaran, Vijay (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ; Shahrooei, Mohammed (Saeed Pathobiology and Genetic Lab) ; Snow, Andrew (Uniformed Services University of the Health Sciences) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ; Tangye, Stuart (Garvan Institute of Medical Research (Darlinghurst, Austràlia)) ; Turvey, Stuart (University of British Columbia) ; Uddin, Furkan (Holy Family Red Crescent Medical College. Centre for Precision Therapeutics. NeuroGen Children's Healthcare. Genetics and Genomic Medicine Centre. NeuroGen Children's Healthcare) ; Uddin, Mohammed J. (Centre for Applied Genomics. Department of Genetics and Genome Biology. Hospital for Sick Children) ; van de Beek, Diederik (Amsterdam UMC. University Medical Center) ; Vazquez, Sara E. (University of California) ; Vinh, Donald C. (McGill University Health Centre) ; von Bernuth, Horst (Charité-Berlin University Hospital Center) ; Zawadzki, Pawel (Molecular Biophysics Division. Faculty of Physics. A. Mickiewicz University) ; Jing, H. (NIAID Clinical Genomics Program. National Institutes of Health) ; Tung, W. (NIAID Clinical Genomics Program. National Institutes of Health) ; Meguro, K. (NIAID Clinical Genomics Program. National Institutes of Health) ; Shaw, E. (NIAID Clinical Genomics Program. National Institutes of Health) ; Jing, Huie (NIAID Clinical Genomics Program. National Institutes of Health) ; Tung, Wesley (NIAID Clinical Genomics Program. National Institutes of Health) ; Shafer, S. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Zheng, L. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Zhang, Z. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Kubo, S. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Chauvin, S. D. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Meguro, K. (NIAID Clinical Genomics Program. National Institutes of Health) ; Shaw, Elana (NIAID Clinical Genomics Program. National Institutes of Health) ; Lenardo, M. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Luthers, Christopher R. (Department of Pharmacology & Molecular Therapeutics. Uniformed Services University of the Health Sciences) ; Bauman, Bradly M. (Department of Pharmacology & Molecular Therapeutics. Uniformed Services University of the Health Sciences) ; Shafer, Samantha (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Zheng, Lixin (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Zhang, Zinan (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Kubo, Satoshi (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Chauvin, Samuel D. (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Lenardo, Michael (Laboratory of Immune System Biology. Division of Intramural Research. NIAID. NIH) ; Lack, Justin (NIAID Collaborative Bioinformatics Resource. Frederick National Laboratory for Cancer Research. Leidos Biomedical Research. Inc.) ; Karlins, Eric (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ; Hupalo, Daniel M. (American Genome Center. Uniformed Services University of the Health Sciences) ; Rosenberger, John (American Genome Center. Uniformed Services University of the Health Sciences) ; Sukumar, Gauthaman (American Genome Center. Uniformed Services University of the Health Sciences) ; Wilkerson, Matthew D. (American Genome Center. Uniformed Services University of the Health Sciences) ; Zhang, Xijun (American Genome Center. Uniformed Services University of the Health Sciences) ; Universitat Autònoma de Barcelona
Clinical outcome upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from silent infection to lethal coronavirus disease 2019 (COVID-19). We have found an enrichment in rare variants predicted to be loss-of-function (LOF) at the 13 human loci known to govern Toll-like receptor 3 (TLR3)- and interferon regulatory factor 7 (IRF7)-dependent type I interferon (IFN) immunity to influenza virus in 659 patients with life-threatening COVID-19 pneumonia relative to 534 subjects with asymptomatic or benign infection. [...]
2020 - 10.1126/science.abd4570
Science, Vol. 370 Núm. 6515 (23 2020) , p. eabd4570  
7.
17 p, 2.5 MB Autoantibodies against type I IFNs in patients with life-threatening COVID-19 / Bastard, Paul (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Rosen, Lindsey B. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Zhang, Qian (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Michailidis, Eleftherios (The Rockefeller University. Laboratory of Virology and Infectious Disease) ; Hoffmann, Hans-Heinrich (The Rockefeller University. Laboratory of Virology and Infectious Disease) ; Zhang, Yu (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Dorgham, Karim (Sorbonne Université. Centre d'Immunologie et des Maladies Infectieuses) ; Philippot, Quentin (University of Paris. Imagine Institute) ; Rosain, Jérémie (University of Paris. Imagine Institute) ; Béziat, Vivien (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Manry, Jeremy (University of Paris. Imagine Institute) ; Shaw, Elana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Haljasmägi, Liis (University of Tartu. Institute of Biomedicine and Translational Medicine) ; Peterson, Pärt (University of Tartu. Institute of Biomedicine and Translational Medicine) ; Lorenzo, Lazaro (University of Paris. Imagine Institute) ; Bizien, Lucy (University of Paris. Imagine Institute) ; Trouillet-Assant, Sophie (Lyon University. International Center of Research in Infectiology) ; Dobbs, Kerry (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Almeida de Jesus, Adriana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Belot, Alexandre (Lyon Immunopathology Federation. Hospices Civils de Lyon) ; Kallaste, Anne (Internal Medicine Clinic. Tartu University Hospital) ; Catherinot, Emilie (Hôpital Foch) ; Tandjaoui-Lambiotte, Yacine (Avicenne Hospital. Assistance Publique Hôpitaux de Paris) ; Le Pen, Jérémie (The Rockefeller University. Laboratory of Virology and Infectious Disease) ; Kerner, Gaspard (University of Paris. Imagine Institute) ; Bigio, Benedetta (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Seeleuthner, Yoann (University of Paris. Imagine Institute) ; Yang, Rui (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Bolze, Alexandre (Helix) ; Spaan, András N. (University Medical Center Utrecht) ; Delmonte, Ottavia M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Abers, Michael S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Aiuti, Alessandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ; Casari, Giorgio (Medical Genetics. IRCCS Ospedale San Raffaele) ; Lampasona, Vito (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ; Piemonti, Lorenzo (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ; Ciceri, Fabio (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ; Bilguvar, Kaya (Yale University School of Medicine. Department of Genetics) ; Lifton, Richard P. (Rockefeller University. Laboratory of Human Genetics and Genomics) ; Vasse, Marc (Consorcio Hospital. General Universitario) ; Smadja, David M. (Paris University. European Georges Pompidou Hospital) ; Migaud, Mélanie (University of Paris. Imagine Institute) ; Hadjadj, Jérome (Hôpital Cochin. Department of Internal Medicine) ; Terrier, Benjamin (Université de Paris. Department of Internal Medicine) ; Duffy, Darragh (Pasteur Institute) ; Quintana-Murci, Lluis (Institut Pasteur. Collège de France) ; van de Beek, Diederik (Amsterdam UMC. University Medical Center) ; Roussel, Lucie (McGill University Health Centre) ; Vinh, Donald C. (McGill University Health Centre) ; Tangye, Stuart (Garvan Institute of Medical Research (Darlinghurst, Austràlia)) ; Haerynck, Filomeen (Ghent University Hospital. (Bèlgica)) ; Dalmau, David (Fundació Docència i Recerca Mútua Terrassa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brodin, Petter (Karolinska Institutet (Estocolm, Suècia)) ; Nussenzweig, Michel (Howard Hughes Medical Institute) ; Boisson-Dupuis, Stephanie (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ; Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ; Vogt, Guillaume (University of Paris. Neglected Human Genetics Laboratory) ; Mogensen, Trine Hyrup (Aarhus University) ; Oler, Andrew J. (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ; Gu, Jingwen (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ; Burbelo, Peter D. (Division of Intramural Research. National Institute of Dental Craniofacial Research (NIDCR). NIH) ; Cohen, Jeffrey I. (Laboratory of Infectious Diseases. Division of Intramural Research. NIAID. NIH) ; Biondi, Andrea (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ; Bettini, Laura Rachele (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ; D'Angio, Mariella (University of Milano-Bicocca. Pediatric Department) ; Bonfanti, Paolo (University of Milano-Bicocca. Department of Infectious Diseases) ; Rossignol, Patrick (University of Lorraine. Plurithematic Clinical Investigation Centre) ; Mayaux, Julien (APHP Pitié-Salpêtrière Hospital) ; Rieux-Laucat, Frédéric (Laboratory of Immunogenetics of Pediatric Autoimmune Diseases. INSERM. UMR 1163. University of Paris. Imagine Institute) ; Husebye, Eystein (Karolinska Institutet (Estocolm, Suècia). Department of Medicine) ; Fusco, Francesca (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ; Ursini, Matilde Valeria (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ; Imberti, Luisa (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ; Sottini, Alessandra (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ; Paghera, Simone (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ; Quiros-Roldan, Eugenia (Department of Infectious and Tropical Diseases. University of Brescia. ASST Spedali di Brescia) ; Rossi, Camillo (Direzione Sanitaria. ASST Spedali Civili di Brescia) ; Castagnoli, Riccardo (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ; Montagna, Daniela (Department of Clinical. Surgical. Diagnostic and Pediatric Sciences. University of Pavia) ; Licari, Amelia (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ; Marseglia, Gian Luigi (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ; Duval, Xavier (Centre d'Investigation Clinique. Inserm CIC 1425. Hôpital Bichat Claude Bernard. APHP) ; Ghosn, Jade (Hôpital Bichat) ; Tsang, John S. (Multiscale Systems Biology Section. Laboratory of Immune System Biology. NIAID. NIH) ; Goldbach-Mansky, Raphaela (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Kisand, Kai (Institute of Biomedicine and Translational Medicine. University of Tartu) ; Lionakis, Michail S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Puel, Anne (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ; Zhang, Shein-Ying (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ; Holland, Steven M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Gorochov, Guy (Département d'Immunologie. AP-HP. Hôpital Pitié-Salpétrière) ; Jouanguy, Emmanuelle (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ; Rice, Charles M. (Laboratory of Virology and Infectious Disease. The Rockefeller University) ; Cobat, Aurélie (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ; Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Abel, Laurent (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ; Su, Helen C. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ; Casanova, Jean-Laurent (Pediatric Hematology and Immunology Unit. Necker Hospital for Sick Children. AP-HP) ; The University of Hong Kong HGID Lab ; The University of Hong Kong NIAID-USUHS Immune Response to COVID Group ; COVID Clinicians ; COVID-STORM Clinicians ; Imagine COVID Group ; French COVID Cohort Study Group ; The Milieu Intérieur Consortium ; CoV-Contact Cohort ; Amsterdam UMC Covid-19 Biobank ; COVID Human Genetic Effort ; Universitat Autònoma de Barcelona
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. [...]
2020 - 10.1126/science.abd4585
Science, Vol. 370 Núm. 6515 (september 2020) , p. eabd4585  
8.
12 p, 1.1 MB Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia : a prospective, observational, genetic study / García Laorden, M. Isabel (Hospital Universitario de Gran Canaria Dr. Negrín) ; Rodríguez de Castro, Felipe (Hospital Universitario de Gran Canaria Dr. Negrín) ; Solé Violán, Jordi (Hospital Universitario de Gran Canaria Dr. Negrín) ; Rajas, Olga (Hospital Universitario de la Princesa (Madrid)) ; Blanquer, José (Hospital Clínic Universitari (València)) ; Borderías, Luis (Hospital General Universitario San Jorge (Osca, Aragó)) ; Aspa, Javier (Hospital Universitario de la Princesa (Madrid)) ; Briones, M. Luisa (Hospital Clínic Universitari (València)) ; Saavedra, Pedro (Universidad de Las Palmas de Gran Canaria) ; Marcos Ramos, J. Alberto (Hospital Dr. José Molina Orosa (Lanzarote)) ; González Quevedo, Nereida (Hospital Universitario de Gran Canaria Dr. Negrín) ; Sologuren, Ithaisa (Hospital Universitario de Gran Canaria Dr. Negrín) ; Herrera-Ramos, Estefanía (Hospital Universitario de Gran Canaria Dr. Negrín) ; Ferrer, José M. (Hospital Universitario de Gran Canaria Dr. Negrín) ; Rello, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín)
Introduction: Genetic variability of the pulmonary surfactant proteins A and D may affect clearance of microorganisms and the extent of the inflammatory response. The genes of these collectins (SFTPA1, SFTPA2 and SFTPD) are located in a cluster at 10q21-24. [...]
2011 - 10.1186/cc10030
Critical Care, Vol. 15, Núm. R57 (February 2011) , p. 1-12
2 documents

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