UAB Digital Repository of Documents 8 records found  Search took 0.02 seconds. 
1.
14 p, 1.7 MB Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis : an evaluation of four automated methods against manual reference segmentations in a multi-center cohort / de Sitter, Alexandra (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Verhoeven, Tom (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Burggraaff, Jessica (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Neurology, MS Center Amsterdam) ; Liu, Yaou (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Simoes, Jorge (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Ruggieri, Serena (San Camillo Forlanini Hospital. Department of Neurosciences) ; Palotai, Miklos (Harvard Medical School. Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital) ; Brouwer, Iman (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Versteeg, Adriaan (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Wottschel, Viktor (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Ropele, Stefan (Medical University of Graz. Department of Neurology) ; Rocca, Mara A. (IRCCS San Raffaele Scientific Institute. Neurology Unit) ; Gasperini, Claudio (San Camillo Forlanini Hospital. Department of Neurosciences) ; Gallo, Antonio (University of Campania "Luigi Vanvitelli". Division of Neurology and MRI Research Center, Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences) ; Yiannakas, Marios C. (University College London. Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology) ; Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Enzinger, Christian (University of Graz. Division of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology Medical) ; Filippi, Massimo (Vita-Salute San Raffaele University) ; De Stefano, Nicola (University of Siena. Department of Neurological and Behavioural Sciences) ; Kappos, Ludwig (University Hospital, Kantonsspital. Department of Neurology) ; Frederiksen, Jette L. (Glostrup University Hospital Copenhagen. Department of Neurology) ; Uitdehaag, Bernard M. J. (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Neurology, MS Center Amsterdam) ; Barkhof, Frederik (UCL London. Institutes of Neurology and Healthcare Engineering) ; Guttmann, Charles R. G. (Harvard Medical School. Center for Neurological Imaging, Department of Radiology, Brigham and Women's Hospital) ; Vrenken, Hugo (Amsterdam Neuroscience, Amsterdam UMC, Location VUmc. Department of Radiology and Nuclear Medicine, MS Center Amsterdam) ; Universitat Autònoma de Barcelona
Deep grey matter (DGM) atrophy in multiple sclerosis (MS) and its relation to cognitive and clinical decline requires accurate measurements. MS pathology may deteriorate the performance of automated segmentation methods. [...]
2020 - 10.1007/s00415-020-10023-1
Journal of Neurology, Vol. 267 (july 2020) , p. 3541-3554  
2.
The long-term outcomes of CIS patients in the Barcelona inception cohort : Looking back to recognize aggressive MS / Tintoré, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arrambide, Georgina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Otero-Romero, Susana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carbonell-Mirabent, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Río, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tur, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nos, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arévalo, María Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Anglada, Elisenda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Menendez, Rebeca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Midaglia, Luciana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galán, Ingrid (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castilló, Joaquin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mulero, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Zabalza, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez-Acevedo, Breogan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodriguez, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Espejo, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sequeira, Joao (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mitjana, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; de Barros, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pareto, Deborah (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Auger, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
To explore the long-term outcomes of patients with clinically isolated syndromes from the Barcelona cohort. We selected patients with a follow-up longer than 10 years to (1) estimate the risks of multiple sclerosis (MS) and disability accumulation according to the baseline number of T2 lesions and to compare treated versus untreated patients and early versus delayed treatment, and (2) to study baseline features of patients with aggressive MS (Expanded Disability Status Scale (EDSS) ⩾6. [...]
2019 - 10.1177/1352458519877810
Multiple sclerosis, Vol. 26 (october 2019) , p. 1658-1669  
3.
10 p, 1.4 MB Urgent challenges in quantification and interpretation of brain grey matter atrophy in individual MS patients using MRI / Amiri, Houshang (Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands) ; de Sitter, Alexandra (Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands) ; Bendfeldt, Kerstin (Medical Image Analysis Center (MIAC AG) Basel, Switzerland) ; Battaglini, Marco (Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy) ; Gandini Wheeler-Kingshott, Claudia A.M. (NMR Research Unit, Department of Neuroinflammation, Queen Square MS Centre, UCL Institute of Neurology, London, UK) ; Calabrese, Massimiliano (Multiple Sclerosis Centre, Neurology Section, Department of Neurosciences, Biomedicine and Movements, University of Verona, Italy) ; Geurts, Jeroen J.G. (Anatomy & Neurosciences, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, The Netherlands) ; Rocca, Maria A. (Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Enzinger, Christian (Department of Neurology & Division of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology, Medical University of Graz, Austria) ; de Stefano, Nicola (Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy) ; Filippi, Massimo (Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy) ; Rovira, Álex (Hospital Universitari Vall d'Hebron) ; Barkhof, Frederik (Institutes of Neurology and Healthcare Engineering, UCL, London, UK) ; Vrenken, Hugo (Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands) ; Universitat Autònoma de Barcelona
Atrophy of the brain grey matter (GM) is an accepted and important feature of multiple sclerosis (MS). However, its accurate measurement is hampered by various technical, pathological and physiological factors. [...]
2018 - 10.1016/j.nicl.2018.04.023
NeuroImage, Vol. 19 (april 2018) , p. 466-475  
4.
13 p, 862.2 KB Deep gray matter volume loss drives disability worsening in multiple sclerosis / Eshaghi, Arman (University College London) ; Prados, Ferran (University College London Hospitals) ; Brownlee, Wallace J. (University College London) ; Altmann, Daniel R. (London School of Hygiene & Tropical Medicine) ; Tur Gómez, Carmen (University College London) ; Cardoso, M. Jorge (University College London) ; De Angelis, Floriana (University College London) ; van de Pavert, Steven H. (University College London) ; Cawley, Niamh (University College London) ; De Stefano, Nicola (University of Siena) ; Stromillo, M. Laura (University of Siena) ; Battaglini, Marco (University of Siena) ; Ruggieri, Serena (University of Rome Sapienza) ; Gasperini, Claudio (S Camillo Forlanini Hospital) ; Filippi, Massimo (Vita-Salute San Raffaele University) ; Rocca, Maria A. (Vita-Salute San Raffaele University) ; Rovira, Àlex (Hospital de la Vall d'Hebron) ; Sastre Garriga, Jaume (Hospital de la Vall d'Hebron) ; Vrenken, Hugo (VU University Medical Centre) ; Leurs, Cyra E. (VU University Medical Center) ; Killestein, Joep (VU University Medical Center) ; Pirpamer, Lukas (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Ourselin, Sebastien (University College London Hospitals) ; Wheeler-Kingshott, Claudia A.M. Gandini (C. Mondino National Neurological Institute) ; Chard, Declan (University College London Hospitals) ; Thompson, Alan J. (University College London) ; Alexander, Daniel C. (University College London) ; Barkhof, Frederik (VU University Medical Centre) ; Ciccarelli, Olga (University College London Hospitals) ; Universitat Autònoma de Barcelona
Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with faster disability accumulation in MS. [...]
2018 - 10.1002/ana.25145
Annals of Neurology, Vol. 83, Issue 2 (February 2018) , p. 210-222  
5.
6 p, 152.3 KB Lesion topographies in multiple sclerosis diagnosis / Arrambide, Georgina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tintoré, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Auger, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Río, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castilló, Joaquín (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galán, Ingrid (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nos, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mitjana, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mulero, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; de Barros, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez-Acevedo, Breogán (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Midaglia, Luciana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca)
To assess the contributions of cortico-juxtacortical and corpus callosum lesions to multiple sclerosis diagnosis and to compare the value of ≥1 vs ≥3 periventricular lesions in clinically isolated syndromes (CIS). [...]
2017 - 10.1212/WNL.0000000000004715
Neurology, Vol. 89 (december 2017) , p. 2351-2356  
6.
9 p, 405.7 KB Neurofilament light chain level is a weak risk factor for the development of MS / Arrambide, Georgina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Espejo, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Eixarch, Herena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Villar, Luisa M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alvarez-Cermeño, José C. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Picón, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Kuhle, Jens (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Disanto, Giulio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Kappos, Ludwig (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pareto, Deborah (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Simon, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Río, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nos, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tur, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castilló, Joaquín (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal-Jordana, Angela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galán, Ingrid (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arévalo, Maria J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Auger, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tintoré, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
To determine the prognostic value of selected biomarkers in clinically isolated syndromes (CIS) for conversion to multiple sclerosis (MS) and disability accrual. Data were acquired from 2 CIS cohorts. [...]
2016 - 10.1212/WNL.0000000000003085
Neurology, Vol. 87 (september 2016) , p. 1076-1084  
7.
9 p, 542.1 KB Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis / Cantó, Ester (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tintoré, Mar ; Villar, Luisa Maria (Hospital Ramón y Cajal. Departamento de Neurología) ; Borrás, Eva (Universitat Pompeu Fabra (UPF). Proteomics Unit) ; Álvarez-Cermeño, Jose Carlos (Hospital Ramón y Cajal. Departamento de Neurología) ; Chiva, Cristina (Pniversitat Pompeu Fabra (UPF). Proteomics Unit) ; Sabidó, Eduard (Universitat Pompeu Fabra (UPF). Proteomics Unit) ; Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron. Unitat de Neuroimmunologia Clínica) ; Universitat Autònoma de Barcelona
In a previous proteomics study using pooled cerebrospinal fluid (CSF) samples, we proposed apolipoprotein AI, apolipoprotein AIV, vitronectin, plasminogen, semaphorin 7A, and ala-β-his-dipeptidase as candidate biomarkers associated with the conversion to clinically definite multiple sclerosis (CDMS) in patients with clinically isolated syndromes (CIS). [...]
2014 - 10.1186/s12974-014-0181-8
Journal of neuroinflammation, Vol. 11 (november 2014)  
8.
2 p, 132.8 KB Diagnòstic precoç de l'esclerosi múltiple / Rovira, Àlex (Hospital de la Vall d'Hebron. Unitat de Ressonància Magnètica)
L'esclerosi múltiple afecta predominantment a dones joves, no es coneix el seu origen ni té tractament curatiu, però pot seguir-se el seu desenvolupament amb tècniques de diagnòstic per imatges, com la ressonància magnètica. [...]
2009
UAB divulga, Octubre 2009, p. 1-2  

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